Faculty Publications Sept. 12-19

This week’s edition of Faculty Publications includes Cedars-Sinai studies that were published Sept. 12-19. If you have a published paper from this period that does not appear on this list, please contact Sue Marone.

Cedars-Sinai in the News

LA 2028 Olympic Organizers Sign New Corporate Sponsors | Los Angeles Times
Cedars-Sinai is identified as the Official Medical Provider for the 2028 Games.

Dr. George Berci, Whose Innovations Changed Surgery, Dies at 103 | The New York Times Online 
George Berci, MD 

Deep Links Between Alcohol and Cancer are Described in new Report | The New York Times 
Jane Figueiredo, PhD 

Report: Cancer Diagnoses are More Common but so is Surviving | NPR/National Public Radio Online 
Jane Figueiredo, PhD 

Understanding 4 of the Most Common Complications of Hypertrophic Cardiomyopathy | TIME Online
Michelle Kittleson, MD, PhD 

3 GIs Honored for IBD Research | Becker’s GI & Endoscopy
Dermot McGovern, MD, PhD 

‘The Mind is Medicine’: How Virtual Reality Can Cool Bothersome Hot Flashes | Healio
Brennan Spiegel, MD

Faculty Publications

Biomedical Sciences

Accelerated CEST Imaging Through Deep Learning Quantification From Reduced Frequency Offsets. Cheema, Karandeep, Pei Han, Hsu-Lei Lee, Yibin Xie, Anthony G. Christodoulou, and Debiao Li. Magnetic Resonance in Medicine, September.

Relationship Between Plaque Burden and Plaque Vulnerability: Acute Coronary Syndromes Versus Chronic Coronary Syndrome. Kinoshita, Daisuke, Keishi Suzuki, Daichi Fujimoto, Takayuki Niida, Eisuke Usui, Yoshiyasu Minami, Damini Dey, Hang Lee, Iris McNulty, Junya Ako, Maros Ferencik, Tsunekazu Kakuta, and Ik-Kyung Jang. Journal of Cardiovascular Computed Tomography, September, S1934-5925(24)00436-2.

Y-Box Binding Protein 1/Cyclin A1 Axis Specifically Promotes Cell Cycle Progression at G2/M Phase in Ovarian Cancer. Murakami, Yuichi, Daisuke Katsuchi, Taichi Matsumoto, Kuon Kanazawa, Tomohiro Shibata, Akihiko Kawahara, Jun Akiba, Nozomu Yanaihara, Aikou Okamoto, Hiroaki Itamochi, Toru Sugiyama, Atsumu Terada, Shin Nishio, Naotake Tsuda, Kiyoko Kato, Mayumi Ono, and Michihiko Kuwano. Scientific Reports 14 (1): 21701.

Association of Serum Endocannabinoid Levels With Pancreatitis and Pancreatitis-Related Pain. Goodman, Marc T., Christina Lombardi, Alexa Torrens, Catherine Bresee, Jami L. Saloman, Liang Li, Yunlong Yang, William E. Fisher, Evan L. Fogel, Christopher E. Forsmark, Darwin L. Conwell, Phil A. Hart, Walter G. Park, Mark Topazian, Santhi S. Vege, Stephen K. Van Den Eeden, Melena D. Bellin, Dana K. Andersen, Jose Serrano, Dhiraj Yadav, Stephen J. Pandol, Daniele Piomelli, and Consortium for the Study of Chronic Pancreatitis, Diabetes, and Pancreatic Cancer (CPDPC). Cannabis and Cannabinoid Research, September.

Improving on Polygenic Scores across Complex Traits Using Select and Shrink With Summary Statistics (S4) and LDpred2. Tyrer, Jonathan P., Pei-Chen Peng, Amber A. DeVries, Simon A. Gayther, Michelle R. Jones, and Paul D. Pharoah. BMC Genomics 25 (1): 878.

The Framework for AI Tool Assessment in Mental Health (FAITA - Mental Health): A Scale for Evaluating AI-Powered Mental Health Tools. Golden, Ashleigh, and Elias Aboujaoude. World Psychiatry 23 (3): 444–45.

Cardiac Surgery

Fate of Abstracts Presented at Annual Meetings of The Society of Thoracic Surgeons From 2015 to 2019. Valdes, Carlos A., Ahmet Bilgili, Griffin Stinson, Ramy M. Sharaf, Omar M. Sharaf, Zachary Brennan, Fabian Jimenez-Contreras, Giles J. Peek, Mark S. Bleiweis, Thomas M. Beaver, and Jeffrey Phillip Jacobs. The Annals of Thoracic Surgery, September, S0003-4975(24)00770-7.

Cardiology 

Practice Patterns of Cardiovascular Magnetic Resonance Use in the Diagnosis of Pediatric Myocarditis: A Survey-Based Study. Jacobs, Hannah M., Jonathan H. Soslow, Matthew D. Cornicelli, Shae A. Merves, Ruchira Garg, Mehul D. Patel, Arpit Agarwal, Nilanjana Misra, Michael P. DiLorenzo, M. Jay Campbell, Jeremy Steele, Jennifer Co-Vu, Joshua D. Robinson, Simon Lee, and Jason N. Johnson. Journal of Cardiovascular Magnetic Resonance, September, 101091.

Diet and Risk of Atrial Fibrillation: A Systematic Review. Gawałko, Monika, Melissa E. Middeldorp, Arnela Saljic, John Penders, Thomas Jespersen, Christine M. Albert, Gregory M. Marcus, Christopher X. Wong, Prashanthan Sanders, and Dominik Linz. European Heart Journal, September, ehae551.

Stopping Trials Early for Benefit: Insights From Recent Pivotal Trials in Chronic Kidney Disease. Kaul, Sanjay, and Javed Butler. Journal of the American College of Cardiology 84 (13): 1268–71.

Moving Toward a Consensus: Comparison of the 2023 ESH and 2017 ACC/AHA Hypertension Guidelines. Vemu, Prasantha L., Eugene Yang, and Joseph E. Ebinger. JACC. Advances 3 (10): 101230.

Computational Biomedicine

Data Enhancement in the Age of Spatial Biology. Liao, Linbu, Patrick C. N. Martin, Hyobin Kim, Sanaz Panahandeh, and Kyoung Jae Won. Advances in Cancer Research 163: 39–70.

Association Between Papillary Thyroid Cancer and Primary Aldosteronism in Individuals With Hypertension. Maciel, Ana Alice W., Debora L. S. Danilovic, Ibere C. Soares, Thais C. Freitas, Jessica Okubo, Gustavo F. C. Fagundes, Felipe Freitas-Castro, Lucas S. Santana, Augusto G. Guimaraes, Vinicius F. Calsavara, Felipe L. Ledesma, Luciana A. Castroneves, Fernando M. A. Coelho, Victor Srougi, Fabio Y. Tanno, Jose L. Chambo, Francisco C. Carnevale, João V. Silveira, Fernanda M. Consolim-Colombo, Luiz A. Bortolotto, Luciana P. Brito, Maria Candida B. V. Fragoso, Luciano F. Drager, Celso E. Gomez-Sanchez, Ana Claudia Latronico, Berenice B. Mendonca, Ana O. Hoff, and Madson Q. Almeida. The Journal of Clinical Endocrinology and Metabolism, September, dgae653.

Validation of the BOADICEA Model for Epithelial Tubo-Ovarian Cancer Risk Prediction in UK Biobank. Yang, Xin, Yujia Wu, Lorenzo Ficorella, Naomi Wilcox, Joe Dennis, Jonathan Tyrer, Tim Carver, Nora Pashayan, Marc Tischkowitz, Paul D. P. Pharoah, Douglas F. Easton, and Antonis C. Antoniou. British Journal of Cancer, September.

Imaging

Evaluating the Prognostic Effectiveness of Stress SPECT Versus PET Myocardial Perfusion Imaging. Rozanski, Alan, and Daniel Berman. Journal of Nuclear Cardiology, September, 102038.

Coronary Artery Calcium for Risk Stratification Among Persons With Very High HDL Cholesterol. Razavi, Alexander C., Anurag Mehta, Nathan D. Wong, Alan Rozanski, Matthew J. Budoff, Eugenia Gianos, Viola Vaccarino, Marly van Assen, Carlo N. De Cecco, Michael D. Miedema, John A. Rumberger, Martin Bødtker Mortensen, Leslee J. Shaw, Khurram Nasir, Roger S. Blumenthal, Anand Rohatgi, Arshed A. Quyyumi, Laurence S. Sperling, Seamus P. Whelton, Michael J. Blaha, Daniel S. Berman, and Omar Dzaye. JACC. Advances 3 (10): 101217.

Medicine

De Novo and Recurrent Post-Transplant Membranous Nephropathy Cases Show Similar Rates of Concurrent Antibody-Mediated Rejection. Khorsandi, Nikka, Hwarang Stephen Han, Raja Rajalingam, Jun Shoji, and Anatoly Urisman. Frontiers in Nephrology 4: 1438065.

Epigenetic Age Acceleration and Cognitive Performance Over Time in Older Adults. Phyo, Aung Zaw Zaw, Zimu Wu, Sara E. Espinoza, Anne M. Murray, Peter D. Fransquet, Jo Wrigglesworth, Robyn L. Woods, and Joanne Ryan. Alzheimer’s & Dementia (Amsterdam, Netherlands) 16 (3): e70010.

Improvements in Digestive Symptoms After Participation in an App-Based Chronic Digestive Disease Management Program: A Prospective Cohort Evaluation. Bravata, Dena M., Hau Liu, Meghan M. Colosimo, Alexander C. Bullock, Erin Commons, and Mark Pimentel. Cureus 16 (8): e66941.

Future Prospects of Metabolic and Bariatric Surgery: A Comprehensive Review. Hage, Karl, Gerardo Perrotta, Richard S. Betancourt, Jamil Danaf, Aryan Gajjar, Daniel Tomey, Katie Marrero, and Omar M. Ghanem. Healthcare (Basel, Switzerland) 12 (17): 1707.

AI for Multistructure Incidental Findings and Mortality Prediction at Chest CT in Lung Cancer Screening. Marcinkiewicz, Anna M., Mikolaj Buchwald, Aakash Shanbhag, Bryan P. Bednarski, Aditya Killekar, Robert J. H. Miller, Valerie Builoff, Mark Lemley, Daniel S. Berman, Damini Dey, and Piotr J. Slomka. Radiology 312 (3): e240541.

Recent Updates on the Management of Split-Thickness Skin Graft Donor Sites. Markel, Justin E., Jacob D. Franke, Kerri M. Woodberry, and Matthew P. Fahrenkopf. Plastic and Reconstructive Surgery. Global Open 12 (9): e6174.

Gasdermin D and Gasdermin E Are Dispensable for Silica-Mediated IL-1β Secretion From Mouse Macrophages. Leung, Jennifer, Michael Chang, Richard E. Moore, Jargalsaikhan Dagvadorj, Fayyaz S. Sutterwala, and Suzanne L. Cassel. ImmunoHorizons 8 (9): 679–87.

Fecundity and Nutrient Deficiency Following Obesity Treatment: Implications for Young-Onset Cancer Risk in Offspring. Barreto, Savio George, Chris Moy, Stephen J. Pandol, and Lilian Kow. Cancers 16 (17): 3099.

Impact of Elevated Serum Triglycerides on Children With Acute Recurrent or Chronic Pancreatitis From INSPPIRE-2. Sellers, Zachary M., Matthew J. Giefer, Fuchenchu Wang, Gretchen A. Cress, Maisam A. Abu-El-Haija, Ankur Chugh, Reuven Z. Cohen, Elissa M. Downs, Douglas S. Fishman, A. Jay Freeman, Cheryl E. Gariepy, Tanja Y. Gonska, Amit S. Grover, Doug Lindblad, Quin Y. Liu, Asim Maqbool, Jacob A. Mark, Brian A. McFerron, Megha S. Mehta, Veronique D. Morinville, Kenneth Ng, Robert A. Noel, Chee Y. Ooi, Emily R. Perito, Madhura Y. Phadke, Wenly Ruan, Sarah Jane Schwarzenberg, David M. Troendle, Michael Wilschanski, Yuhua Zheng, Ying Yuan, Mark E. Lowe, Aliye Uc, and Consortium for the Study of Chronic Pancreatitis, Diabetes and Pancreatic Cancer. The Journal of Pediatrics, September, 114298.

Effect of Semaglutide on Physical Function, Body Composition, and Biomarkers of Aging in Older Adults With Overweight and Insulin Resistance: Protocol for an Open-Labeled Randomized Controlled Trial. Cortes, Tiffany M., Libia Vasquez, Monica C. Serra, Ronna Robbins, Allison Stepanenko, Kevin Brown, Hannah Barrus, Annalisa Campos, Sara E. Espinoza, and Nicolas Musi. JMIR Research Protocols 13 (September): e62667.

Population-Based Screening Cohort Study Reveals No Association Between Monoclonal Gammopathy of Undetermined Significance (MGUS), Smoldering Multiple Myeloma (SMM), Multiple Myeloma (MM), and Alopecia. Sharma, Divija, Benjamin Ungar, Jonas A. Adalsteinsson, Jon Kristinn Sigurdsson, Kelley Sharp, Sigrún Thorsteinsdóttir, Saemundur Rögnvaldsson, Ásdís R. Þórðardóttir, Brynjar Viðarsson, Páll T. Önundarson, Bjarni A. Agnarssond, Margrét Sigurðardóttird, Ingunn Þorsteinsdóttir, Ísleifur Ólafsson, Elías Eyþórsson, Ásbjörn Jónsson, Andri Ólafsson, Gauti Kjartan Gíslason, Ola Landgren, Malin Hulcrantz, Brian Gm Durie, Stephen Harding, Thorvardur Jon Love, and Sigurdur Yngvi Kristinsson. Archives of Dermatological Research 316 (9): 627.

Anti-CD38 Monoclonals for Treatment of Antibody-Mediated Rejection in Renal Allografts. Jordan, Stanley C. Transplantation, September.

Revised REACH-B Model for Hepatocellular Carcinoma Risk Prediction in Patients With Chronic Hepatitis B. Yang, Ju Dong, and Patrick S. Kamath. Annals of Internal Medicine, September.

A Novel Murine Syngeneic CD8 Peripheral T-Cell Lymphoma Model With Preclinical Applications. Milshteyn, Larry, Anton Villamejor, Akil Merchant, and Joseph Lownik. Leukemia & Lymphoma, September, 1–7.

Low Booster Uptake in Cancer Patients Despite Health Benefits. Figueiredo, Jane C., Julia Levy, So Yung Choi, Alexander M. Xu, Noah M. Merin, Omid Hamid, Tucker Lemos, Nathalie Nguyen, Maimoona Nadri, Alma Gonzalez, Simeon Mahov, Justin M. Darrah, Jun Gong, Ronald L. Paquette, Alain C. Mita, Robert A. Vescio, Sarah J. Salvy, Inderjit Mehmi, Andrew E. Hendifar, Ronald Natale, Warren G. Tourtellotte, V. Krishnan Ramanujan, Carissa A. Huynh, Kimia Sobhani, Karen L. Reckamp, and Akil A. Merchant. iScience 27 (9): 110596.

Neurology 

Site- and Frequency-Specific Enhancement of Visual Search Performance With Online Individual Alpha Frequency (IAF) Repetitive Transcranial Magnetic Stimulation (rTMS) to the Inferior Frontal Junction. Luber, Bruce, Lysianne Beynel, Zhi-De Deng, Lawrence Gregory Appelbaum, Tristan Jones, Austin Harrison, David L. K. Murphy, Eric Lo, Richard A. McKinley, and Sarah H. Lisanby. Cerebral Cortex (New York, N.Y.: 1991) 34 (9): bhae371.

Neurosurgery

Mechanical Thrombectomy Versus Intravenous Thrombolysis in Distal Medium Vessel Acute Ischemic Stroke: A Multinational Multicenter Propensity Score-Matched Study. Salim, Hamza Adel, Vivek Yedavalli, Basel Musmar, Nimer Adeeb, Muhammed Amir Essibayi, Kareem El Naamani, Nils Henninger, Sri Hari Sundararajan, Anna Luisa Kühn, Jane Khalife, Sherief Ghozy, Luca Scarcia, MAD MT Investigators, et al. Journal of Stroke, September.

Predictive Value of Follow-up Infarct Volume on Functional Outcomes in Middle Cerebral Artery M2 Segment Vessel Occlusion Stroke Treated With Mechanical Thrombectomy. Yedavalli, Vivek, Hamza Adel Salim, Basel Musmar, Nimer Adeeb, Kareem El Naamani, Nils Henninger, Sri Hari Sundararajan, Anna Luisa Kühn, Jane Khalife, Sherief Ghozy, Luca Scarcia, Benjamin Yq Tan, Adam A. Dmytriw, et al. European Stroke Journal, September, 23969873241275531.

OBGYN

Financial Toxicity: Moving From Describing the Problem Toward Developing Interventions. Liang, Margaret I. Gynecologic Oncology 189 (October): A1–2.

Orthopaedics

Knee Osteoarthritis: Disease Burden, Available Treatments, and Emerging Options. Langworthy, Michael, Vinod Dasa, and Andrew I. Spitzer. Therapeutic Advances in Musculoskeletal Disease 16: 1759720X241273009.

Injectable PLGA Microscaffolds With Laser-Induced Enhanced Microporosity for Nucleus Pulposus Cell Delivery. Nakielski, Paweł, Alicja Kosik-Kozioł, Chiara Rinoldi, Daniel Rybak, Namdev More, Jacob Wechsler, Tomasz P. Lehmann, Maciej Głowacki, Bogusz Stępak, Magdalena Rzepna, Martina Marinelli, Massimiliano Lanzi, Dror Seliktar, Sarah Mohyeddinipour, Dmitriy Sheyn, and Filippo Pierini. Small, September, e2404963.

Radiographic Accuracy of Identifying Anterolateral Tibial Plafond Involvement in Pronation Abduction Ankle Fractures. Robles, Abrianna S., Zachary A. Rockov, Melissa M. Gross, Brett A. Ewing, Charles M. Lieder, Brian M. Weatherford, Ashley E. Levack, John M. Garlich, Justin M. Haller, Jeffrey S. Earhart, and Geoffrey S. Marecek. Journal of Orthopaedic Trauma, September.

Pathology and Laboratory Medicine

Accuracy and Efficacy of Ion Robotic-Assisted Bronchoscopic Fine Needle Aspiration of Lung Lesions. Boac, Bernadette M., Manita Kanathanavanich, Xiaomo Li, Taryne Imai, Xuemo Fan, Ann E. Walts, Alberto M. Marchevsky, and Shikha Bose. Journal of the American Society of Cytopathology, August, S2213-2945(24)00191-1.

Characterizing Veteran Suicide Decedents That Were Not Classified as High-Suicide-Risk. Levis, Maxwell, Monica Dimambro, Joshua Levy, Vincent Dufort, Abby Fraade, Max Winer, and Brian Shiner. Psychological Medicine, September, 1–10.

Acceptance of Emerging Renal Oncocytic Neoplasms: A Survey of Urologic Pathologists. Mohanty, Sambit K., Anandi Lobo, Shilpy Jha, Ankur R. Sangoi, Mahmut Akgul, Kiril Trpkov, Ondrej Hes, Rohit Mehra, Michelle S. Hirsch, Holger Moch, Steven C. Smith, Rajal B. Shah, Sean R. Williamson, et al. Virchows Archiv: An International Journal of Pathology, September.

Maternal Glucose Levels and Late Pregnancy Circulating Extracellular Vesicle and Particle miRNAs in the MADRES Pregnancy Cohort. Anderson, Elizabeth C., Helen B. Foley, Joshua J. Levy, Megan E. Romano, Jiang Gui, Jessica L. Bentz, Luis E. Maldonado, Shohreh F. Farzan, Theresa M. Bastain, Carmen J. Marsit, Carrie V. Breton, and Caitlin G. Howe. Epigenetics 19 (1): 2404198.

Radiation Oncology

Long-Term Follow-Up With Brachytherapy Salvage Reirradiation. Kamrava, Mitchell. Journal of Clinical Oncology, September, JCO2400930.

Surgery

Antimicrobial Prescription Patterns for Acute Sinusitis 2015-2022: A Comparison to Published Guidelines. Dhar, Sarit, Dhruv S. Kothari, Ana L. Tomescu, Brian D’Anza, Kenneth Rodriguez, Anthony Sheyn, and Sanjeet V. Rangarajan. American Journal of Rhinology & Allergy, September, 19458924241280379.

Ponsegromab for the Treatment of Cancer Cachexia. Groarke, John D., Jeffrey Crawford, Susie M. Collins, Shannon Lubaczewski, Eric J. Roeland, Tateaki Naito, Andrew E. Hendifar, Marie Fallon, Koichi Takayama, Timothy Asmis, Richard F. Dunne, Isik Karahanoglu, Carrie A. Northcott, Magdalena A. Harrington, Michelle Rossulek, Ruolun Qiu, and Aditi R. Saxena. The New England Journal of Medicine, September.

Robotic and Laparoscopic Adrenalectomy for Pheochromocytoma: An International Multicenter Study. Parente, Alessandro, Kevin Verhoeff, Yanbo Wang, Nanya Wang, Zhicheng Wang, Maciej Śledziński, Andrzej Hellmann, Marco Raffaelli, Francesco Pennestrì, Mark Sywak, Alexander J. Papachristos, Fausto F. Palazzo, International Pheo Study Group, et al. European Urology Focus, September, S2405-4569(24)00168-8.

Hidden Hernias Hurt: A Plea for Early Diagnosis and Treatment of Occult Inguinal Hernias. Wong, Harry J., Cherin Oh, and Shirin Towfigh. Surgical Endoscopy, September.

Urology

Fatigue Management in Advanced Prostate Cancer: Real-World Insights From Qualitative Interviews With Patients. Freedland, Stephen J., Marty Chakoian, Ted Wells, Nader El-Chaar, Alexandra Colon, Dina Elsouda, and Agnes Hong. Clinical Genitourinary Cancer 22 (6): 102209.

Real-World Outcomes Following Biochemical Recurrence After Definitive Therapy With a Short Prostate-Specific Antigen Doubling Time: Potential Role of Early Secondary Treatment. Freedland, Stephen J., Wei Gao, Angela Lax, Hongbo Yang, Krishnan Ramaswamy, David Russell, Agnes Hong, and Jasmina I. Ivanova. Prostate Cancer and Prostatic Diseases, September.

Microglial and Neuronal Fates Following Inhibition of CSF-1R in Synucleinopathy Mouse Model. Iba, Michiyo, Yeon-Joo Lee, Liam Horan-Portelance, Katherine Chang, Marcell Szabo, Robert A. Rissman, Sungyong You, Eliezer Masliah, and Changyoun Kim. Brain, Behavior, and Immunity, September, S0889-1591(24)00619-6.