Faculty Publications Oct. 15-22
A Comprehensive Digest of Research Publications From Cedars-Sinai Investigators and a Sampling of Recent Media Coverage Featuring Faculty
This week’s edition of Faculty Publications includes Cedars-Sinai studies that were published Oct. 15-22. If you have a published paper from this period that does not appear on this list, please contact Sue Marone.
Cedars-Sinai in the News
Is Longevity Medicine Going Mainstream? | The New York Times
Sara Espinoza, MD
Creatine Isn’t Just for Athletes. Here’s Who Should Be Taking It (Hint: Probably You) | Los Angeles Times
Tracy Zaslow, MD
Shoulder Replacement Surgery: Types, Recovery Timeline and Costs | U.S. News & World Report
Brian Lee, MD
California’s Early Flu Season: How 4 Systems Are Responding | Becker’s Clinical Leadership
Jonathan Grein, MD
Why Do I Have a (Literal) Pain in My Butt—And How Can I Relieve It? | Prevention
Andrew Bach, DO
Better Conversations, Better Choices: Shared Decision-Making in Prostate Cancer Care | Medscape
Timothy Daskivich, MD
‘That’s What ChatGPT Told Me’: How AI Is Entering the Exam Room | Becker’s Clinical Leadership
Yaron Elad, MD
With Health AI Moving Faster Than its Safeguards, AFROTECHTM Speaker Dr. Tiffani Bright Sees an Opening | AFROTECH
Tiffani Bright, PhD
Can Memory Care Facilities Keep Residents Behind Locked Doors? What Families Should Know | LTC News
Shouri Lahiri, MD
Faculty Publications
Biomedical Sciences
A Single-Cell Atlas of Diabetes-Associated Remodeling in the Human Corneal Limbus. Zha, Daxian, Yizhou Wang, Ruchi Shah, Shaghaiegh M. Ebrahimi, Adam J. Poe, Cynthia Amador, Jake Inzalaco, Andrew Fealy, Onkar B. Sawant, Andrei A. Kramerov, Zhiping P. Wang, Alexander V. Ljubimov, and Mehrnoosh Saghizadeh. The Ocular Surface, October, S1542-0124(26)00127-8.
Inflammatory Biomarkers Show Sex-Specific Associations With Cardiometabolic Disease and Coronary Atherosclerosis as Assessed by Coronary CT Angiography. Bittner, Daniel O., Caroline Roesner, Dorette Raaz-Schrauder, Markus Goeller, Damini Dey, Tobias Kilian, Stephan Achenbach, and Mohamed Marwan. American Journal of Preventive Cardiology 31 (January): 101718.
Maximising the Prognostic Value of Non-Contrast Cardiac CT. Khaing, Phyo H., Tara Zuhair Kassem, Shaun Khanna, Piotr Slomka, and Damini Dey. European Heart Journal. Cardiovascular Imaging, October, jeag284.
The Pyrin Inflammasome Senses OCTN2-Mediated Uptake of Extracellular ʟ-Carnitine From Muscle Injury or Ingestion. Elliott, Eric I., Tomomi M. Yoshida, Susana C. B. R. Nakandakari, Scott Pope, Cuiling Zhang, Timothy Nottoli, Jae Jin Chae, Daniel L. Kastner, Richard A. Flavell, Vishwa Deep Dixit, Vijay A. Rathinam, Fayyaz S. Sutterwala, and Andrew Wang. Cell, October, S0092-8674(26)01117-7.
Toward a Living Meta-Framework for Evaluating Generative AI in Mental Health. Golden, Ashleigh Sarah, and Elias Aboujaoude. Jmir Ai 5 (October): e89211.
Visualization of Post-STEMI Myocardial Infarction and Microvascular Obstruction With Non-Contrast, Free-Breathing Whole-Heart iT2prep-IR BOOST. Liu, Xin, Jifang He, Bowen Zhang, Lu Liang, null Bin Sun, Boqia Xie, Xiuqin Jia, Xiaojuan Guo, Jing An, Chen Zhang, René M. Botnar, Claudia Prieto, Karl P. Kunze, Rohan Dharmakumar, Hsin-Jung Yang, and Qi Yang. Journal of Cardiovascular Magnetic, October, 102814.
Cardiology
Clinical and Genetic Characteristics of Hereditary Arrhythmias and Cardiomyopathies in the Middle East. Ahmad, Omar, Huzaifa Muhammad, Pattara Rattanawong, Abdullah Alissa, Zuhair Al-Hassnan, Dania Mohty, Bandar Alghamdi, Najmeddine Echahidi, Sumeet S. Chugh, and Win-Kuang Shen. Mayo Clinic Proceedings. Innovations, Quality & Outcomes 10 (6): 100760.
Comparison of AI-Enabled Cardiac Chambers Volumetry Based on Non-Gated Chest CT Scans With Echocardiography: An AI-CVD Study Within the Multi-Ethnic Study of Atherosclerosis (MESA). Mirjalili, Seyed Reza, Kyle Atlas, Anthony P. Reeves, Chenyu Zhang, Jakob Wasserthal, Amir Azimi, Ali Hashemi, Mohammadhossein Mozafarybazargany, Amir Ghaffari Jolfayi, Thomas Atlas, Claudia I. Henschke, David F. Yankelevitz, Javier J. Zulueta, Wenjun Fan, Jeffrey I. Mechanick, Andrea D. Branch, Khurram Nasir, Zahi Fayad, Michael V. McConnell, Jamal S. Rana, Rozemarijn Vliegenthart, David J. Maron, Jagat Narula, Matthew J. Budoff, Roxana Mehran, Kim A. Williams, Prediman K. Shah, Oren Mechanic, Arthur S. Agatston, Robert A. Kloner, Nathan D. Wong, and Morteza Naghavi. American Journal of Preventive Cardiology 31 (January): 101731.
Design of Screening Cardiometabolic Opportunities Using Transformative Echocardiography Artificial Intelligence (SCOUT-Echo-AI). Eusuff, Sahir, Jay Kim, Zara Fatima, Dilek Yalcinkaya, Yuki Sahashi, Alexander Sandhu, Long H. Nguyen, Andrew P. Ambrosy, Paul P. Cheng, Stephanie T. Chang, Alan S. Go, Faraz S. Ahmad, Amanda Cheung, Susan Cheng, Alan C. Kwan, and David Ouyang. American Heart Journal, October, 107628.
Heart Failure and Atrial Fibrillation Prediction From Non-Gated Chest CT Scans Using AI-Based Cardiac Chamber Volumetry: An AI-CVD Study Within the Multi-Ethnic Study of Atherosclerosis (MESA). Mirjalili, Seyed Reza, Kyle Atlas, Anthony P. Reeves, Chenyu Zhang, Jakob Wasserthal, Amir Azimi, Ali Hashemi, Mohammadhossein Mozafarybazargany, Amir Ghaffari Jolfayi, Thomas Atlas, Claudia I. Henschke, David F. Yankelevitz, Javier J. Zulueta, Wenjun Fan, Jeffrey I. Mechanick, Andrea D. Branch, Khurram Nasir, Zahi Fayad, Michael V. McConnell, Jamal S. Rana, Rozemarijn Vliegenthart, David J. Maron, Jagat Narula, Matthew J. Budoff, Roxana Mehran, Kim A. Williams, Prediman K. Shah, Oren Mechanic, Arthur S. Agatston, Robert A. Kloner, Nathan D. Wong, and Morteza Naghavi. American Journal of Preventive Cardiology 31 (January): 101732.
Longitudinal Changes in Left Ventricular Structure and Function During a Dietary Weight-Management Trial in Adults With Heart Failure, Type 2 Diabetes, and Obesity: A Secondary Analysis of Pro-HEART. Evangelista, Lorraine S., Rebecca Meraz, Alona D. Angosta, Angelina P. Nguyen, Kelly L. Wierenga, Jennifer Kawi, Michele A. Hamilton, and Gregg C. Fonarow. Nutrients 18 (19): 3238.
Long-Term Safety and Procedural Performance of an Interatrial Shunt for Heart Failure According to Ejection Fraction. Rodés-Cabau, Josep, Gregg W. Stone, Saibal Kar, Stefan Verheye, Ariel Roguin, Jeroen Bax, Antoni Bayes-Genis, Julio Nunez, Jeremiah Depta, Michal Laufer-Perl, Gil Moravsky, Alicia Romero, Edgard Prihadi, Eugene S. Chung, Matthew J. Price, Michael Chenier, Dimitry Schewel, Sachin Kumar, Stephan Kische, Kunjan Bhatt, Kevin S. Shah, Daniel J. Donovan, Suzanne Hendrix, Patrick O’Keefe, William T. Abraham, Michael R. Zile, Stefan D. Anker, Neal L. Eigler, JoAnn Lindenfeld, and RELIEVE-HF Investigators. JACC. Heart Failure, October, 103375.
Psychosocial Vulnerability and Immediate Emotional Triggers Preceding Sudden Cardiac Arrest. Pope, Marita Knudsen, Harpriya Chugh, Audrey Uy-Evanado, Kotoka Nakamura, Angelo Salvucci, Jonathan Jui, Kyndaron Reinier, and Sumeet S. Chugh. JACC. Clinical Electrophysiology, October, S2405-500X(26)00867-4.
Transcatheter Edge-to-Edge Repair in Advanced Heart Failure and Ventricular Dysfunction: An Evolving Heart Team Strategy. AlBadri, Ahmed, Moody Makar, James Burke, Salvotore Mannino, Jennifer Giuseffi, Rajnish Prasad, Gagandeep Joshi, and Abdul Latif Bikak. JACC. Case Reports, October, 110759.
Vascular Risk Factors and Late-Onset Epilepsy. Choi, Hyunmi, Jose Gutierrez, Tian Wang, Minghua Liu, Cheng-Shiun Leu, Sylwia Misiewicz, Jiying Han, Natalie A. Bello, Mary L. Biggs, Emily M. Briceño, Adam M. Brickman, James F. Burke, Ligong Chen, Lisandro D. Colantonio, Stefany P. Diaz Andino, Mitchell S. V. Elkind, Annette L. Fitzpatrick, Christopher Gonzalez Corona, Rebecca F. Gottesman, Alden L. Gross, Lei Huang, Emily L. Johnson, W. Craig Johnson, Deborah A. Levine, W. T. Longstreth, Sofia Pelagalli Maia, Richard P. Mayeux, Brian C. Petersen, Oluwadamilola Obalana, Dolly Reyes-Dumeyer, Tatjana Rundek, Danurys Sanchez, Steven J. Shea, Kevin Strobino, Sarah E. Tom, Carolyn W. Zhu, and Evan L. Thacker. JAMA Neurology, October.
Whole Heart Atherosclerosis Volume and Risk for Major Adverse Cardiovascular Events Across the Clinical Likelihood for Obstructive CAD; the CONFIRM2 Study. Rosendael, Alexander van, Rine Nakanishi, Jeroen J. Bax, Gianluca Pontone, Saima Mushtaq, Ronny R. Buechel, Christoph Gräni, Gudrun Feuchtner, Pietro G. Lacaita, Amit R. Patel, Cristiane C. Singulane, Andrew D. Choi, Ibrahim Danad, et al. American Journal of Preventive Cardiology 31 (January): 101712.
Imaging
Giant Infected Splenic Pseudocyst Complicated by Rupture in a Patient With Chronic Q Fever. Lee, Jonathan, Michelle Chen, Travis H. Smith, Eric D. Cyphers, Adam T. Miller, Tapas Tejura, Monica Deshmukh, and Ali Gholamrezanezhad. Radiology Case Reports 21 (12): 6439–44.
Medicine
Cobimetinib + Vemurafenib in Patients With BRAF V600E-Mutant Papillary Thyroid and Biliary Tract Cancers: Results From the TAPUR Study. Diamond-Rossi, Samantha A., Michael Rothe, Elizabeth Garrett-Mayer, Evan Pisick, Jonathan Bleeker, Apar Kishor Ganti, Funda Meric-Bernstam, Justin T. Moyers, Suresh G. Nair, Kunal C. Kadakia, Nitin Rohatgi, Vaibhav Sahai, Namrata Vijayvergia, Philip J. Gold, Manish R. Sharma, Dominique C. Hinshaw, Abigail Gregory, Gina N. Grantham, Susan Halabi, and Richard L. Schilsky. JCO Precision Oncology 10 (10): e2600703.
Movement Regimens Drive Region-Specific Humeral Adaptation: Whole-Bone Insights From an Experimental Animal Model. Bergren, Sarah, Tea Jashashvili, Mark Dowdeswell, and Kristian J. Carlson. Bone, October, 118139.
Nationwide Trends of Six Medications for Alcohol Use Disorder Prescriptions Post-Discharge in Patients Hospitalized With Alcohol-Associated Liver Disease between 2015 and 2024. Chan, Shu-Yen, Yee Hui Yeo, Hsien Yao Yang, Wei Zhang, and Peng-Sheng Ting. Drug and Alcohol Dependence 288 (October): 113376.
New Horizons in Pharmacotherapy for Cushing’s Disease and Acromegaly. Fleseriu, Maria, Shlomo Melmed, and Artak Labadzhyan. Endocrine-Related Cancer, October, ERC-26-0317.
Neurology
Feasibility of High-Intensity Interval Exercise in Young Adult Survivors of Pediatric Brain Tumor and Young Adults With Isocitrate Dehydrogenase-Mutant Gliomas (HYPE): Protocol for a Randomized Controlled Trial. Cox, Elizabeth, Meghan Tahbaz, Ellaney Matarese, Rebekah L. Wilson, L. Nicolas Gonzalez Castro, Hajime Uno, Tabitha Cooney, Jordan Lane, Mary K. Norris, Kira Bona, Rahela Aziz-Bose, and Christina M. Dieli-Conwright. JMIR Research Protocols 15 (October): e88718.
H3K9me3 Inhibition Reverses Alzheimer’s Progression by Restoring Synaptic and Immune Proteostasis Across the Brain-Retina Axis. Fuchs, Dieu-Trang, Jean-Philippe Vit, Altan Rentsendorj, Yosef Koronyo, Julia Sheyn, Bhakta Prasad Gaire, Saba Shahin, Haoshen Shi, Oksana Chepurna, Miyah R. Davis, Jered W. Wilson, Stuart L. Graham, Vivek K. Gupta, Lon S. Schneider, Michael T. Kleinman, Tao Sun, Margaret Fahnestock, David A. Horne, Mehdi Mirzaei, Keith L. Black, and Maya Koronyo-Hamaoui. Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association 22 (10): e71918.
Integration of Neuroimaging Signatures of Aging and Alzheimer’s With Fluid Biomarkers. Gonzales, Mitzi M., Ngoc Huynh Ho, David H. Wang, Tanweer Rashid, Sachintha R. Brandigampala, Mengjin Dong, David Martinez, Sokratis Charisis, Timothy J. Hohman, Sudha Seshadri, Christos Davatzikos, Gladys Maestre, Tiffany F. Kautz, Ashley LaRoche, Vanessa M. Young, Anna Campbell Sullivan, Kristine Yaffe, Jon B. Toledo, Alzheimer’s Disease Neuroimaging InitiativeHABS‐HD Study Team, and Mohamad Habes. Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association 22 (10): e71889.
Orthopaedics and Sports Medicine
Impact of Age at Surgery on Perioperative Outcomes After Posterior Spinal Fusion for Neuromuscular Scoliosis. Chan, Vivien, Prudhvi Kodali, Sophie Nuytten, Justin L. Reyes, Mehdi Elfilali, Michael G. Vitale, Zeeshan M. Sardar, and David L. Skaggs. Journal of the Pediatric Orthopaedic Society of North America 17 (November): 100457.
Pathology and Laboratory Medicine
Integrating ctDNA-Based ESR1m Monitoring into First-Line Care for ER+, HER2- Advanced Breast Cancer: A Consensus Workflow. Abdou, Yara, Amber Cipriani, Trevor Feinstein, Ryan Haumschild, Mabel Mardones, Joanne Mortimer, and Eric Vail. The Oncologist, October, oyag411.
Microvascular Inflammation in Kidney Transplants: Finally an Effective Treatment? Haas, Mark, Jean Hou, and Agnes B. Fogo. Kidney International 110 (5): 1102–5.
Renal Tubule-Specific Nrf2 Deletion Ameliorates Diabetic Kidney Disease by Attenuating Glomerular Hypertension and Kidney Injury in a Mouse Model of Diabetes. Su, Ke, Jing Zhou, Yuchao Pang, Shiao-Ying Chang, Min-Chun Liao, Wen-Xia Yang, Shuiling Zhao, Junzheng Peng, Daniel N. Leal, Michifumi Yamashita, Kana N. Miyata, Janos G. Filep, Julie R. Ingelfinger, Shao-Ling Zhang, and John S. D. Chan. Diabetologia, October.
Radiation Oncology
Dose Mapping and Accumulation for Re-Irradiation of Lung Cancers: Methodological Principles, Uncertainties, Quality Assurance, and Practical Clinical Considerations. Rosu-Bubulac, Mihaela, Hualiang Zhong, and Indrin Julian Chetty. Journal of Clinical Medicine 15 (19): 7527.
Radiation Vasculopathy of the Coronary Arteries: State-of-the Art Review. Xia, Jeffrey, Jean Kim, Abhishek Sharma, Benjamin Yang, Prasanna G. Alluri, Katelyn Atkins, Eric D. Miller, Terence M. Williams, Daniel Addison, Amit Arbune, Alvin Chandra, Efstratios Koutroumpakis, Kathleen W. Zhang, and Vlad G. Zaha. Circulation 154 (16): 1627–45.
Surgery
A Rare Case of Gallbladder Torsion With Incidental Stage IIIB Gallbladder Adenocarcinoma. Marty, Makenna, Jonathan Zuo, Linan Wang, and Marc A. Attiyeh. Journal of Surgical Case Reports 2026 (10): rjag929.
Accuracy, Potential Harm, Weight Stigma, and Commercial Influence in Short-Form Social Media Content on Incretin-Based Therapies for Obesity. Yoon, Yeo-Jun, Amanda Velazquez, Sehej-Leen Parmar, Katayoun Lotfi, Denise Wong, Cagney Cristancho, Katherine Salim, Seongwon Jeon, Sangmo Hong, Hyungoo Shin, Caroline M. Apovian, and Dong Wook Kim. Frontiers in Endocrinology 17: 1844311.
Management of Acquired Velopharyngeal Insufficiency in Adults: A Systematic Review and Meta-Analysis. Kothari, Dhruv Shreedhar, Arash Abiri, Jon Mallen-St Clair, and Neelaysh Vukkadala. The Laryngoscope, October.
Technical Versatility of Pedicled Latissimus Dorsi-Based Flaps for Refractory Spinal CSF Leaks: A Three-Case Series. Satea, Murtaja, José Maria Zepeda Torres, Alaa Ibrahim Mohammed Jorani, Ahmed Mohammed Khaffaf, Jonathan Mokhtar, Elio Nader, Haïzam Oubari, and Alexandre G. Lellouch. JPRAS Open 0 (0).
Cedars-Sinai Health Sciences University is advancing groundbreaking research and educating future leaders in medicine, biomedical sciences and allied health sciences. Learn more about the university.