Faculty Publications Oct. 31-Nov.7

This week’s edition of Faculty Publications includes Cedars-Sinai studies that were published Oct. 31-Nov. 7. If you have a published paper from this period that does not appear on this list, please contact Sue Marone.

Cedars-Sinai in the News

Scientists are Looking Into the Benefits of Growing Human Tissue in Space | NPR Online/Morning Edition
Arun Sharma, PhD 

Cedars-Sinai Establishes New University | Beverly Press/Park LaBrea News
Peter L. Slavin, MD, and Shlomo Melmed, MBChB 

National Academy of Medicine Elects 100 New Members: Part 4 | OncoDaily
David Rowitch, MD, PhD 

Scientists Successfully Reverse Liver Fibrosis in Mice | HealthDay
Shelley Lu, MD 

Why Epilepsy in Children is Easily Missed | BlackDoctor
Deborah Holder, MD 

AI Colonoscopies: More Benign Lesion Removals, Potentially Higher Costs | MedPage Today
Brennan Spiegel, MD 

Can Blood Tests Help Detect Cancer? | HealthCentral
Robert Figlin, MD 

Ozempic May Help With Your Knee Pain Too, According to New Research | Prevention
Bert Mandelbaum, MD

Faculty Publications

Anesthesiology

Rationale for Assessing Preoperative Anxiety as Part of the Preoperative Evaluation Process. White, Paul F., and Ofelia Loani Elvir-Lazo. Journal of Clinical Anesthesia, October, 111656.

Biomedical Sciences

Editorial: Multifaceted Cannabinoids: Regulators of Normal and Pathological Function in Metabolic and Endocrine Organs, Volume II. Meccariello, Rosaria, Kanikkai Raja Aseer, Morvarid Kabir, and Antonietta Santoro. Frontiers in Endocrinology 15: 1503017. Trimodality Therapy for Bladder Cancer. Singh, Parminder, Leslie Ballas, Guru P. Sonpavde, Ronald C. Chen, Rick Bangs, Brian C. Bauman, Himanshu Nagar, Scott E. Delacroix, Seth P. Lerner, and Jason A. Efstathiou. Bladder Cancer (Amsterdam, Netherlands) 10 (3): 199–213.

Targeting erbB Pathways in Breast Cancer: Dual Kinase Inhibition for Brain Metastasis and Prevention of p185HER2/Neu Tumor Development. Goel, Peeyush N., Makoto Katsumata, Wei Qian, Sunil Mathur, Mei Q. Ji, Arabinda Samanta, Payal Grover, George Sgouros, Jenny C. Chang, and Mark I. Greene. Breast Cancer (Dove Medical Press) 16: 725–33.

Multi-Omics After O-GlcNAc Alteration Identified Cellular Processes Promoting Aneuploidy After Loss of O-GlcNAc Transferase. Boyd, Samuel S., Dakota R. Robarts, Khue Nguyen, Maite Villar, Ibtihal M. Alghusen, Manasi Kotulkar, Aspin Denson, Halyna Fedosyuk, Stephen A. Whelan, Norman C. Y. Lee, John Hanover, Wagner B. Dias, Ee Phie Tan, Steven R. McGreal, Antonio Artigues, Russell H. Swerdlow, Jeffrey A. Thompson, Udayan Apte, and Chad Slawson. Molecular Metabolism, October, 102060.

Coronary Plaque Radiomic Phenotypes Predict Fatal or Nonfatal Myocardial Infarction: Analysis of the SCOT-HEART Trial. Kolossváry, Márton, Andrew Lin, Jacek Kwiecinski, Sebastien Cadet, Piotr J. Slomka, David E. Newby, Marc R. Dweck, Michelle C. Williams, and Damini Dey. JACC. Cardiovascular Imaging, October, S1936-878X(24)00376-0.

Diabetes, IL-10 and the Brain’s Microvascular Crisis. Riera, Celine E. Nature Metabolism, November.

Using Extended Reality to Enhance Effectiveness and Group Identification in Remote Group Therapy for Anxiety Disorders: A Critical Analysis. Bouguettaya, Ayoub, and Elias Aboujaoude. JMIR Formative Research 8 (November): e64494.

Cardiac Surgery

Valve Sparing Aortic Root Replacement In ATAAD: A Superior Long-Term Solution. Cohen, Robbin G. The Annals of Thoracic Surgery, October, S0003-4975(24)00881-6.

Cardiology

Transcatheter Interventions in Tricuspid Regurgitation: Shifting the Focus Beyond Quantity of Life to Quality of Life. Gupta, Aakriti, Celina Yong, and Rasha Al-Lamee. Journal of the American College of Cardiology, October, S0735-1097(24)10053-8.

Quality of Life After Transcatheter Tricuspid Valve Replacement: 1-Year Results From TRISCEND II Pivotal Trial. Arnold, Suzanne V., Rebecca T. Hahn, Vinod H. Thourani, Raj Makkar, Moody Makar, Rahul P. Sharma, Christiane Haeffele, Charles J. Davidson, Akhil Narang, Brian O’Neill, James Lee, Pradeep Yadav, Firas Zahr, Scott Chadderdon, Mackram Eleid, Sorin Pislaru, Robert Smith, Molly Szerlip, Brian Whisenant, Nishant Sekaran, Santiago Garcia, Terri Stewart-Dehner, Paul A. Grayburn, Anna Sannino, Clayton Snyder, Yiran Zhang, Michael J. Mack, Martin B. Leon, Philipp Lurz, Susheel Kodali, David J. Cohen, and TRISCEND II Pivotal Trial Investigators. Journal of the American College of Cardiology, October, S0735-1097(24)09954-6.

Sudden Death in Obesity: Mechanisms and Management. Holmstrom, Lauri, Juhani Junttila, and Sumeet S. Chugh. Journal of the American College of Cardiology, October, S0735-1097(24)08510-3.

Classification of Primary Mitral Regurgitation Using Extramitral Cardiac Involvement in Patients Undergoing Transcatheter Edge-to-Edge Repair. Kaewkes, Danon, Alon Shechter, Vivek Patel, Ofir Koren, Keita Koseki, Tarun Chakravarty, Mamoo Nakamura, Moody Makar, and Raj Makkar. Catheterization and Cardiovascular Interventions, October.

The Mitochondrial Citrate Carrier SLC25A1 Regulates Metabolic Reprogramming and Morphogenesis in the Developing Heart. Ohanele, Chiemela, Jessica N. Peoples, Anja Karlstaedt, Joshua T. Geiger, Ashley D. Gayle, Nasab Ghazal, Fateemaa Sohani, Milton E. Brown, Michael E. Davis, George A. Porter, Victor Faundez, and Jennifer Q. Kwong. Communications Biology 7 (1): 1422.

Editors’ Note. Kittleson, Michelle. The Journal of Heart and Lung Transplantation 43 (11): 1818–19.

Continuous Versus Intermittent Blood Pressure Monitoring in Postpartum Preeclampsia With Severe Features. Woolcock Martinez, Helen, Noora Haghighi, Anne-Sophie van Wingerden, Michael Kirschner, Whitney Alexandra Booker, Natalie A. Bello, Nils Petersen, and Eliza Miller. American Journal of Perinatology, November.

Artificial Intelligence Applied to Coronary Artery Calcium Scans (AI-CAC) Significantly Improves Cardiovascular Events Prediction. Naghavi, Morteza, Anthony P. Reeves, Kyle Atlas, Chenyu Zhang, Thomas Atlas, Claudia I. Henschke, David F. Yankelevitz, Matthew J. Budoff, Dong Li, Sion K. Roy, Khurram Nasir, Sabee Molloi, Zahi Fayad, Michael V. McConnell, Ioannis Kakadiaris, David J. Maron, Jagat Narula, Kim Williams, Prediman K. Shah, Daniel Levy, and Nathan D. Wong. NPJ Digital Medicine 7 (1): 309.

Impact of a Chronic Total Occlusion on Outcomes After FFR-Guided PCI or Coronary Bypass Surgery: A FAME 3 Substudy. Otsuki, Hisao, Kuniaki Takahashi, Frederik M. Zimmermann, Kreton Mavromatis, Adel Aminian, Nikola Jagic, Jan-Henk E. Dambrink, Petr Kala, Philip MacCarthy, Nils Witt, Yuhei Kobayashi, Tatsunori Takahashi, Y. Joseph Woo, Alan C. Yeung, Bernard De Bruyne, Nico H. J. Pijls, William F. Fearon, and FAME 3 Trial Investigators. Circulation. Cardiovascular Interventions, November, e014300.

Integration of Point-of-Care Ultrasound in a Nurse Practitioner-Led Heart Failure Clinic. Craigo, Christina Light, Theresa Brown, Ilan Kedan, Deborah Koniak-Griffin, and Holli A. DeVon. Journal of the American Association of Nurse Practitioners, November.

Computational Biomedicine

Germline Copy Number Variants and Endometrial Cancer Risk. Stylianou, Cassie E., George A. R. Wiggins, Vanessa L. Lau, Joe Dennis, Andrew N. Shelling, Michelle Wilson, Peter Sykes, Frederic Amant, Daniela Annibali, Wout De Wispelaere, Douglas F. Easton, Peter A. Fasching, Dylan M. Glubb, Ellen L. Goode, Diether Lambrechts, Paul D. P. Pharoah, Rodney J. Scott, Emma Tham, Ian Tomlinson, Manjeet K. Bolla, Fergus J. Couch, Kamila Czene, Thilo Dörk, Alison M. Dunning, Olivia Fletcher, Montserrat García-Closas, Reiner Hoppe, ABCTB Investigators, Helena Jernström, Rudolf Kaaks, Kyriaki Michailidou, Nadia Obi, Melissa C. Southey, Jennifer Stone, Qin Wang, Amanda B. Spurdle, Tracy A. O’Mara, John Pearson, and Logan C. Walker. Human Genetics, November.

Imaging

Clinical Correlates of a Single-Item Physical Activity Questionnaire Among Patients Undergoing Stress SPECT Myocardial Perfusion Imaging. Rozanski, Alan, Heidi Gransar, Robert Jh Miller, Donghee Han, Sean Hayes, John Friedman, Louise Thomson, and Daniel Berman. Journal of Nuclear Cardiology, October, 102066.

Prognostic Value of Left Ventricular Mass Measured on Coronary Computed Tomography Angiography. Abiragi, Michael, Melanie Chen, Billy Lin, Heidi Gransar, Damini Dey, Piotr Slomka, Sean W. Hayes, Louise E. Thomson, John D. Friedman, Daniel S. Berman, and Donghee Han. Journal of Cardiovascular Computed Tomography, November, S1934-5925(24)00460-X.

Medicine

Hepatocellular Carcinoma Risk Prediction and Early Detection in Patients With Metabolic Dysfunction Associated Steatotic Liver Disease. Liang, Jeff, Naomy Kim, and Ju Dong Yang. Translational Gastroenterology and Hepatology 9: 67.

A Case of Rapidly Progressive Unilateral Non-Nephrogenic Hemorrhagic Bullous Calciphylaxis Responding to Systemic Sodium Thiosulfate Therapy. Wetstone, Rachel, Rebecca Yim, Colleen Gabel, Kaitlyn Yim, Patrick O’Donnell, and Fnu Nutan. Wounds: A Compendium of Clinical Research and Practice 36 (10): 338–41.

Triple Combination of Hepatic Arterial Infusion Chemotherapy, Immune Checkpoint Inhibitors, and Tyrosine Kinase Inhibitors for Treatment of Advanced Hepatocellular Carcinoma: More Robust Evidence Is Still Needed. Rezaee-Zavareh, Mohammad Saeid, and Ju Dong Yang. Chinese Clinical Oncology 13 (5): 77.

Liver Cancer in 2021: Global Burden of Disease Study. Tan, En Ying, Pojsakorn Danpanichkul, Jie Ning Yong, Zhenning Yu, Darren Jun Hao Tan, Wen Hui Lim, Benjamin Koh, Ryan Yan Zhe Lim, Ethan Kai Jun Tham, Kartik Mitra, Asahiro Morishita, Yao-Chun Hsu, Ju Dong Yang, Hirokazu Takahashi, Ming-Hua Zheng, Atsushi Nakajima, Cheng Han Ng, Karn Wijarnpreecha, Mark D. Muthiah, Amit G. Singal, and Daniel Q. Huang. Journal of Hepatology, October, S0168-8278(24)02652-7.

Risk of Hepatocellular Carcinoma in Subcentimeter Liver Nodules Identified on Surveillance Ultrasound: A Systematic Review. Koo, Eden, Karim Seif El Dahan, Darine Daher, Nicole E. Rich, Sukul Mittal, Ju Dong Yang, Neehar D. Parikh, and Amit G. Singal. Clinical Gastroenterology and Hepatology, October, S1542-3565(24)00976-5.

Willingness of Women at Increased Risk of Breast Cancer to Participate in Prevention Trials. Mastrogiacomo, Cecilia N., Alexa Courtepatte, Anne Moyer, Christina Preece, Patricia Thompson, and Alison Stopeck. JCO Oncology Practice, October, OP2400487.

ACR Appropriateness Criteria® Altered Mental Status, Coma, Delirium, and Psychosis: 2024 Update. Expert Panel on Neurological Imaging, Bruno P. Soares, Robert Y. Shih, Pallavi S. Utukuri, Megan Adamson, Matthew J. Austin, Richard K. J. Brown, Judah Burns, Kelsey Cacic, Sammy Chu, Cathy Crone, Jana Ivanidze, Christopher D. Jackson, Aleks Kalnins, Christopher A. Potter, Sonja Rosen, Karl A. Soderlund, Ashesh A. Thaker, Lily L. Wang, and Bruno Policeni. Journal of the American College of Radiology: JACR 21 (11S): S372–83.

Machine Learning-Based Clustering Identifies Obesity Subgroups With Differential Multi-Omics Profiles and Metabolic Patterns. Anwar, Mohammad Y., Heather Highland, Victoria Lynn Buchanan, Mariaelisa Graff, Kristin Young, Kent D. Taylor, Russell P. Tracy, Peter Durda, Yongmei Liu, Craig W. Johnson, Francois Aguet, Kristin G. Ardlie, Robert E. Gerszten, Clary B. Clish, Leslie A. Lange, Jingzhong Ding, Mark O. Goodarzi, Yii-Der Ida Chen, Gina M. Peloso, Xiuqing Guo, Maggie A. Stanislawski, Jerome I. Rotter, Stephen S. Rich, Anne E. Justice, Ching-Ti Liu, and Kari North. Obesity (Silver Spring, Md.) 32 (11): 2024–34.

Pan-Cancer Survival Impact of Immune Checkpoint Inhibitors in a National Healthcare System. Miller, Sean R., Matthew Schipper, Lars G. Fritsche, Ralph Jiang, Garth Strohbehn, Erkin Ötleş, Benjamin H. McMahon, Silvia Crivelli, Rafael Zamora-Resendiz, Nithya Ramnath, Shinjae Yoo, Xin Dai, Kamya Sankar, Donna M. Edwards, Steven G. Allen, Michael D. Green, and Alex K. Bryant. Cancer Medicine 13 (21): e70379.

Factor 3 Regulates Airway Engraftment by Human Bronchial Basal Cells. Reynolds, Susan D., Cynthia L. Hill, Alfahdah Alsudayri, Jacob T. Stack, Kimberly M. Shontz, Gianni Carraro, Barry R. Stripp, and Tendy Chiang. Stem Cells Translational Medicine, November, szae084.

IFSO Bariatric Endoscopy Committee Evidence-Based Review and Position Statement on Endoscopic Sleeve Gastroplasty for Obesity Management. Dayyeh, Barham K. Abu, Christine Stier, Aayed Alqahtani, Reem Sharaiha, Mohit Bandhari, Silvana Perretta, Sigh Pichamol Jirapinyo, Gerhard Prager, and Ricardo V. Cohen. Obesity Surgery, November.

Metabolic Syndrome and Risks of Breast Cancer Outcomes for Luminal, Triple-Negative, and HER2-Overexpressing Subtypes. Loroña, Nicole C., Megan Othus, Kathleen E. Malone, Hannah M. Linden, Mei-Tzu C. Tang, and Christopher I. Li. Cancer Epidemiology, Biomarkers & Prevention: A Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology, November.

Cardiac Motion Correction With a Deep Learning Network for Perfusion Defect Assessment in SPECT Myocardial Perfusion Imaging. Zhang, Xirang, Yongyi Yang, P. Hendrik Pretorius, Piotr J. Slomka, and Michael A. King. Journal of Nuclear Cardiology, November, 102071.

Recommendations for Aligned Nomenclature of Peripheral Nervous System Disorders Across Rheumatology and Neurology. Noaiseh, Ghaith, Anahita Deboo, Jennifer K. King, Arun Varadhachary, George Sarka, Brent P. Goodman, Katherine M. Hammitt, Julie Frantsve-Hawley, Robert Fox, Matthew C. Baker, Stamatina Danielides, Steven Mandel, Pantelis P. Pavlakis, R. Hal Scofield, Daniel J. Wallace, Nancy Carteron, and Steven Carsons. Arthritis & Rheumatology (Hoboken, N.J.), November.

Extended Monitoring for Transition to Oral Corticosteroids in Acute Severe Ulcerative Colitis May Be Unnecessarily Prolonging Length of Stay. Ear, Sapphire, James Cordero, Ryan McConnell, Fernando Velayos, Uma Mahadevan, and Sara Lewin. Digestive Diseases and Sciences, November.

Phase II Randomized Study of Maintenance Atezolizumab (A) Versus Atezolizumab + Talazoparib (AT) in Patients With SLFN11 Positive Extensive Stage Small Cell Lung Cancer. S1929. Karim, Nagla Abdel, Jieling Miao, Karen L. Reckamp, Carl M. Gay, Lauren A. Byers, Ying-Qi Zhao, Mary W. Redman, Daniel R. Carrizosa, Wei-Lien Wang, William J. Petty, Kathan Mehta, Bryan A. Faller, Edem S. Agamah, Samer S. Kasbari, Rajini K. Malisetti, Atul Kumar, John Schallenkamp, Krishna C. Alluri, Jhanelle E. Gray, and Karen Kelly. Journal of Thoracic Oncology, November, S1556-0864(24)02431-6.

Bacterial Contamination of Autologous Blood Salvaged During Deceased Donor Liver Transplantation: A Prospective Observational Study. Kim, Doyeon, Sangbin Han, Ju Dong Yang, Ji-Hye Kwon, Gyu-Sung Choi, Jong Man Kim, Yoon Joo Chung, Chisong Chung, Justin S. Ko, Mi Sook Gwak, Jae-Won Joh, and Gaab Soo Kim. Scientific Reports 14 (1): 26785.

Qualitative and Quantitative Analysis of 18F-GP1 Positron Emission Tomography in Thrombotic Cardiovascular Disease. Whittington, Beth, Evangelos Tzolos, Shruti Joshi, Rong Bing, Jack Andrews, Krithika Loganath, Neil Craig, Craig Balmforth, Laura Clark, Christophe Lucatelli, Mark G. MacAskill, Adriana A. S. Tavares, Tim Clark, Nicholas L. Mills, Jennifer Nash, Damini Dey, Piotr J. Slomka, Norman Koglin, Andrew W. Stephens, Marc R. Dweck, Michelle C. Williams, William Whiteley, Edwin J. R. van Beek, Joanna M. Wardlaw, and David E. Newby. Scientific Reports 14 (1): 26792.

Cognitive Decline in Cushing’s Syndrome: A Systematic Review. Katragadda, Anila, Jessica Kunadia, Polly Kirsch, Brenda Dorcely, Shruti Shah, Zachary Henig, Asha Job, Richard A. Feelders, and Nidhi Agrawal. Journal of Neuroendocrinology, November, e13466.

Representation of Women and Racial Minorities in SGLT2 Inhibitors and Heart Failure Clinical Trials. Gupta, Rahul, Chukwuemeka Umeh, Tamanna Mohta, Ajay Vaidya, Aaron Wolfson, Jonathan Nattiv, Harpreet Bhatia, Gagan Kaur, Raghav Dhawan, Puja Darji, Benson Eghreriniovo, Eseosa Sanwo, Priya Hotwani, Payaam Mahdavian, Sabina Kumar, and Bhoodev Tiwari. International Journal of Cardiology. Heart & Vasculature 55 (December): 101539.

Neurosurgery

Indication-Based Analysis of Laser Interstitial Thermal Therapy: A Propensity Score-Matched Comparison of Outcomes for Brain Tumor Versus Epilepsy Indications. Miller, Andrew M., Shane Shahrestani, Michelot Michel, John S. Yu, and Adam Mamelak. Neurosurgical Focus 57 (5): E8.

Obstructive Hydrocephalus of Uncommon Etiology: Case Report and Neurosurgical Management of Aqueductal Web Presenting in Adolescence. Masarwy, Aseel, Christopher Watterson, Andre Boyke, David Bonda, and Moise Danielpour. Child’s Nervous System: ChNS, November.

Nursing

Normalcy Among Individuals Living With Long-Term Mechanical Circulatory Support: A Reflexive Thematic Analysis. Dzou, Tiffany, and Huibrie C. Pieters. Journal of Advanced Nursing, November.

Orthopaedics

Spondylolisthesis in Young Patients in a Large National Cohort: Reoperation Rate Depends on Surgical Approach. Nilssen, Paal K., Nakul Narendran, Ryan A. Finkel, Kenneth D. Illingworth, and David L. Skaggs. The Journal of Bone and Joint Surgery. American Volume, October.

Prolotherapy in the Treatment of Sports-Related Tendinopathies: A Systematic Review of Randomized Controlled Trials. Capotosto, Salvatore, Alireza K. Nazemi, David E. Komatsu, and James Penna. Orthopaedic Journal of Sports Medicine 12 (11): 23259671241275087.

Pediatrics

Effective Drug Design Screening in Bacterial Glycolytic Enzymes via Targeting Alternative Allosteric Sites. Turkmenoglu, Ipek, Gamze Kurtulus, Cenk Sesal, Ozge Kurkcuoglu, Merve Ayyildiz, Serkan Celiker, Fatih Ozhelvaci, Xin Du, George Y. Liu, Moshe Arditi, and Ebru Demet Akten. Archives of Biochemistry and Biophysics 762 (October): 110190.

Surgery

Dynamic Evolution of Fibroblasts Revealed by Single Cell RNA Sequencing of Human Pancreatic Cancer. Dimitrieva, Slavica, Jon M. Harrison, Jonathan Chang, Michelle Piquet, Mari Mino-Kenudson, Millicent Gabriel, Vivek Sagar, Heiko Horn, Kasper Lage, Julie Kim, Gang Li, Shaobu Weng, Cynthia Harris, Anupriya S. Kulkarni, David T. Ting, Motaz Qadan, Peter J. Fagenholz, Cristina R. Ferrone, Angelo L. Grauel, Tyler Laszewski, Alina Raza, Markus Riester, Tim Somerville, Joel P. Wagner, Glenn Dranoff, Jeffrey A. Engelman, Audrey Kauffmann, Rebecca Leary, Andrew L. Warshaw, Keith D. Lillemoe, Carlos Fernandez-Del Castillo, David A. Ruddy, Andrew S. Liss, and Viviana Cremasco. Cancer Research Communications, November.

Interdisciplinary Operating Room Ergonomics Needs and Priorities: A Survey of Operating Room Staff. Mah, Alexis, Fahad Alam, Jeremie Larouche, Marie-Antonette Dandal, Tara Cohen, Susan Hallbeck, Hamid Norasi, Csilla Kallocsai, Sapna Sriram, James D. Helman, and Julie Hallet. Annals of Surgery, November.

Urology

Prostate Cancer in Transgender Women - Challenges in Research and Clinical Care. Nik-Ahd, Farnoosh, Jennifer T. Anger, Matthew R. Cooperberg, and Stephen J. Freedland. Nature Reviews. Urology, November.