Faculty Publications Oct. 10-17

This week’s edition of Faculty Publications includes Cedars-Sinai studies that were published Oct. 10-17. If you have a published paper from this period that does not appear on this list, please contact Sue Marone.

Cedars-Sinai in the News

New Stents for Infants Mean Kids Could Avoid Series of Open Heart Operations | NBC News Online 
Evan Zahn, MD 

Is Adrenal Fatigue Real? | TIME Online
Anat Ben-Shlomo, MD 

‘Failure to Rescue’: Study Suggests why Women Fare Worse Than Men After Cardiovascular Surgery | STAT News
Joanna Chikwe, MD 

Jim Harbaugh to Return to Sidelines this Week | Good Morning America
Ashkan Ehdaie, MD 

Carpal Tunnel Rates are Up. Experts Blame These 4 Factors. | Yahoo! Life
M. Ramin Modabber, MD 

Faculty Publications

Biomedical Sciences

Cell Therapy for Neurological Disorders. Svendsen, Soshana P., and Clive N. Svendsen. Nature Medicine 30 (10): 2756–70.

Patient-Specific Myocardial Infarction Risk Thresholds From AI-Enabled Coronary Plaque Analysis. Miller, Robert J. H., Nipun Manral, Andrew Lin, Aakash Shanbhag, Caroline Park, Jacek Kwiecinski, Aditya Killekar, Priscilla McElhinney, Hidenari Matsumoto, Aryabod Razipour, Kajetan Grodecki, Alan C. Kwan, Donghee Han, Keiichiro Kuronuma, Guadalupe Flores Tomasino, Jolien Geers, Markus Goeller, Mohamed Marwan, Heidi Gransar, Balaji K. Tamarappoo, Sebastien Cadet, Victor Y. Cheng, Stephan Achenbach, Stephen J. Nicholls, Dennis T. Wong, Lu Chen, J. Jane Cao, Daniel S. Berman, Marc R. Dweck, David E. Newby, Michelle C. Williams, Piotr J. Slomka, and Damini Dey. Circulation. Cardiovascular Imaging 17 (10): e016958.

Myocardial Extracellular Volume Measurement Using Cardiac Computed Tomography.  Muthalaly, Rahul G., Timothy Abrahams, Andrew Lin, Kush Patel, Sean Tan, Damini Dey, Donghee Han, Balaji K. Tamarappoo, Stephen J. Nicholls, and Nitesh Nerlekar. The International Journal of Cardiovascular Imaging, October.

Surface Tension Enables Induced Pluripotent Stem Cell Culture in Commercially Available Hardware During Spaceflight. Mozneb, Maedeh, Madelyn Arzt, Pinar Mesci, Dylan M. N. Martin, Stephany Pohlman, George Lawless, Shankini Doraisingam, Sultan Al Neyadi, Rayyanah Barnawi, Ali Al Qarni, Peggy A. Whitson, John Shoffner, Jana Stoudemire, Stefanie Countryman, Clive N. Svendsen, and Arun Sharma. NPJ Microgravity 10 (1): 97.

Cardiac Surgery

Impact of Hospital Transfers on Cardiac Surgery Outcomes: A Society of Thoracic Surgeons Adult Cardiac Surgery Database Analysis. Ganapathi, Asvin M., Levi N. Bonnell, Michael E. Bowdish, Jeffrey P. Jacobs, Tsuyoshi Kaneko, Bryan A. Whitson, and Robert H. Habib. The Annals of Thoracic Surgery, October, S0003-4975(24)00841-5.

Cardiac Donation After Circulatory Death: Teasing Out the Details. DiChiacchio, Laura, Akbarshakh Akhmerov, and Dominic Emerson. The Annals of Thoracic Surgery, October, S0003-4975(24)00860-9.

Cardiology

Serum Potassium Monitoring Using AI-Enabled Smartwatch Electrocardiograms.  Chiu, I.-Min, Po-Jung Wu, Huan Zhang, J. Weston Hughes, Albert J. Rogers, Laleh Jalilian, Marco Perez, Chun-Hung Richard Lin, Chien-Te Lee, James Zou, and David Ouyang. JACC. Clinical Electrophysiology, September, S2405-500X(24)00752-7.

Unusual Presentation of Metastatic Medullary Thyroid Cancer Involving Bone Marrow, Kidneys, and Adrenal Gland: A Literature Review Based on a Case Report. Ebrahimi, Pouya, Moloud Payab, Alireza Shariati, Neda Alipour, Aysan Nozheh, Seyed Mohammad Tavangar, Homa Taheri, and Mahbube Ebrahimpur. Cancer Reports (Hoboken, N.J.) 7 (10): e70022.

Dysregulation of Protein SUMOylation Networks in Huntington’s Disease R6/2 Mouse Striatum.  Kachemov, Marketta, Vineet Vaibhav, Charlene Smith, Niveda Sundararaman, Marie Heath, Devon F. Pendlebury, Andrea Matlock, Alice Lau, Eva Morozko, Ryan G. Lim, Jack Reidling, Joan S. Steffan, Jennifer E. Van Eyk, and Leslie M. Thompson. Brain: A Journal of Neurology, October, awae319.

Multicenter Pivotal Study of the Alterra Adaptive Prestent for the Treatment of Pulmonary Regurgitation. Dimas, V. Vivian, Vasilis Babaliaros, Dennis Kim, D. Scott Lim, Gareth Morgan, Thomas K. Jones, Aimee K. Armstrong, Darren Berman, Jamil Aboulhosn, Vaikom S. Mahadevan, Matthew J. Gillespie, David Balzer, Thomas Zellers, Xiao Yu, Girish Shirali, Anitha Parthiban, Jonathan Leipsic, Philipp Blanke, Evan Zahn, and Shabana Shahanavaz. JACC. Cardiovascular Interventions 17 (19): 2287–97.

Steps Towards Curing Yentl Syndrome: Appraising Sex Differences in Circulating Proteins and Incident Myocardial Infarction. Barton, Anna K., Emily S. Lau, and Martha Gulati. European Heart Journal, October, ehae657.

Cardio-Oncology and Heart Failure: AL Amyloidosis for the Heart Failure Clinician: A Supplement to the Scientific Statement From the Heart Failure Society of America. Bloom, Michelle Weisfelner, Jacqueline B. Vo, Jo E. Rodgers, Alana M. Ferrari, Anju Nohria, Anita Deswal, Richard K. Cheng, Michelle M. Kittleson, Jenica N. Upshaw, Nicolas Palaskas, Anne Blaes, Sherry-Ann Brown, Bonnie Ky, Daniel Lenihan, Mathew S. Maurer, Anecita Fadol, Kerry Skurka, Christine Cambareri, and Ana Barac. Journal of Cardiac Failure, October, S1071-9164(24)00364-6.

Optical Spectroscopic Detection and Typing of Cardiac Amyloidosis. Mukherjee, Sudipta S., Joseph J. Maleszewski, Daniel Luthringer, Matthew P. Confer, Anirudh Mittal, Surendra Dasari, Ellen D. McPhail, Suraj Kapa, Thenkurussi Kesavadas, Andre Kajdacsy-Balla, Evan Kransdorf, Jai Raman, and Rohit Bhargava. Circulation 150 (16): 1299–1301.

Postpartum Blood Pressure Variability and Heart Rate Variability in Preeclampsia. Wingerden, Anne-Sophie van, Maria Katsidoniotaki, Noora Haghighi, Casandra Almonte, Helen Woolcock Martinez, Eduard Valdes, Pedro Castro, Aymen Alian, Whitney Booker, Natalie Bello, Randolph S. Marshall, Ioannis A. Kougioumtzoglou, Nils Petersen, and Eliza Miller. Hypertension (Dallas, Tex.: 1979), October.

Prospective Clinical Evaluation of Deep Learning for Ultrasonographic Screening of Abdominal Aortic Aneurysms. Chiu, I.-Min, Tien-Yu Chen, You-Cheng Zheng, Xin-Hong Lin, Fu-Jen Cheng, David Ouyang, and Chi-Yung Cheng. NPJ Digital Medicine 7 (1): 282.

Computational Biomedicine

Race and Ethnicity and Clinician Linguistic Expressions of Doubt in Hospital Admission Notes.  Lee, Courtney R., Jaya Aysola, Xinwei Chen, Eden Addisu, Ari Klein, Davy Weissenbacher, Graciela Gonzalez-Hernandez, and Gary E. Weissman. JAMA Network Open 7 (10): e2438550.

PAGER: A Novel Genotype Encoding Strategy for Modeling Deviations From Additivity in Complex Trait Association Studies. Freda, Philip J., Attri Ghosh, Priyanka Bhandary, Nicholas Matsumoto, Apurva S. Chitre, Jiayan Zhou, Molly A. Hall, Abraham A. Palmer, Tayo Obafemi-Ajayi, and Jason H. Moore. BioData Mining 17 (1): 41.

The Journey to Building a Diverse, Equitable, and Inclusive American Medical Informatics Association. Bright, Tiffani J., Oliver J. Bear Don’t Walk Iv, Carl Erwin Johnson, Carolyn Petersen, Patricia C. Dykes, Krista G. Martin, Kevin B. Johnson, Lois Walters-Threat, Catherine K. Craven, Robert J. Lucero, Gretchen P. Jackson, and Rubina F. Rizvi. Journal of the American Medical Informatics Association: JAMIA, October, ocae258.

High vs. Low Intensity Behavior Therapy Delivered to Adolescents With ADHD: Potential Adverse Long-Term Effects on Substance Use Outcomes. Kelley, Megan, Margaret H. Sibley, Stefany J. Coxe, Hana Basu, Samantha M. Margherio, Steven W. Evans, and Frances L. Wang. Research on Child and Adolescent Psychopathology, October.

Medicine

Macrophages in Lung Repair and Fibrosis. Jannini-Sá, Yago A. P., Brecht Creyns, Cory M. Hogaboam, William C. Parks, and Miriam S. Hohmann. Results and Problems in Cell Differentiation 74: 257–90.

Palbociclib in Patients With Head and Neck Cancer and Other Tumors With CDKN2A Alterations: Results From the Targeted Agent and Profiling Utilization Registry Study. Worden, Francis P., Evan Pisick, Michael Rothe, Pam K. Mangat, Elizabeth Garrett-Mayer, Maged F. Khalil, Daniel R. Carrizosa, Jessica R. Bauman, Rom S. Leidner, Herbert L. Duvivier, Siqing Fu, Min S. Park, Kathleen J. Yost, Carmen J. Calfa, Alissa S. Marr, Ani S. Balmanoukian, Deepti Behl, Timothy L. Cannon, Lisle Nabell, Steven Francis Powell, Ramya Thota, Dominique C. Hinshaw, Abigail Gregory, Gina N. Grantham, Susan Halabi, and Richard L. Schilsky. JCO Precision Oncology 8 (October): e2400477.

Recovery From COVID-19-Related Disruptions in Cancer Detection. Kim, Uriel, Johnie Rose, Bryan T. Carroll, Richard S. Hoehn, Eric Chen, Jeremy S. Bordeaux, and Siran M. Koroukian. JAMA Network Open 7 (10): e2439263.

Meeting Report From the 2023 Cure Ocular Melanoma (CURE OM) Global Science Meeting, Philadelphia, PA, November 2023. Seedor, Rino S., Andrew E. Aplin, Corine Bertolotto, Richard D. Carvajal, Nigel Deacon, Katie Doble, Omid Hamid, Rizwan Haq, Miriam Kadosh, Shaheer Khan, Jacqueline Kraska, Jose Lutzky, Meredith McKean, Kamaneh Montazeri, Justin Moser, Michael Onken, Marlana Orloff, Joseph J. Sacco, Keiran Smalley, and Sara M. Selig. Pigment Cell & Melanoma Research, October.

High-Dimensional Analysis of NK Cells in Kidney Transplantation Uncovers Subsets Associated With Antibody-Independent Graft Dysfunction. Ruan, Dan Fu, Miguel Fribourg, Yuko Yuki, Yeon-Hwa Park, Maureen P. Martin, Haocheng Yu, Geoffrey C. Kelly, Brian H. Lee, Ronaldo M. de Real, Rachel Lee, Daniel Geanon, Seunghee Kim-Schulze, Nicholas Chun, Paolo Cravedi, Mary Carrington, Peter S. Heeger, and Amir Horowitz. JCI Insight, October, e185687.

A Case of Adenosquamous Pancreatic Cancer With a KRAS G12C Mutation With an Exceptional Response to Immunotherapy.  Ahmed, Murtaza, Brent K. Larson, Arsen Osipov, Nilofer Azad, and Andrew Hendifar. Oncotarget 15 (October): 741–47.

Competing and Noncompeting Risk Models for Predicting Kidney Allograft Failure. Truchot, Agathe, Marc Raynaud, Ilkka Helanterä, Olivier Aubert, Nassim Kamar, Gillian Divard, Brad Astor, Christophe Legendre, Alexandre Hertig, Matthias Buchler, Marta Crespo, Enver Akalin, Gervasio Soler Pujol, Maria Cristina Ribeiro de Castro, Arthur J. Matas, Camilo Ulloa, Stanley C. Jordan, Edmund Huang, Ivana Juric, Nikolina Basic-Jukic, Maarten Coemans, Maarten Naesens, John J. Friedewald, Helio Tedesco Silva, Carmen Lefaucheur, Dorry L. Segev, Gary S. Collins, and Alexandre Loupy. Journal of the American Society of Nephrology: JASN, October.

Regulation of the NLRP3 Inflammasome by Autophagy and Mitophagy. Gupta, Suman, Suzanne L. Cassel, Fayyaz S. Sutterwala, and Jargalsaikhan Dagvadorj. Immunological Reviews,

Unraveling the Hepatoprotective and Anti-Pancreatic Cancer Potential of Caralluma Europaea: A Comprehensive in Vivo, in Vitro and in Silico Evidence. Amrati, Fatima Ez-Zahra, Adrian Lim, Meryem Slighoua, Mohamed Chebaibi, Ibrahim Mssillou, Aziz Drioiche, Francesca Di Cristo, Yazeed A. Al-Sheikh, Mourad A. M. Aboul-Soud, Mouad Edderkaoui, and Dalila Bousta. Drug and Chemical Toxicology, October, 1–16.

Imaging in Inflammatory Bowel Disease. Kumar, Rashmi, Gil Y. Melmed, and Phillip Gu. Rheumatic Diseases Clinics of North America 50 (4): 721–33.

Neurology

Multicenter Validation of Automated Detection of Paramagnetic Rim Lesions on Brain MRI in Multiple Sclerosis. Chen, Luyun, Zheng Ren, Kelly A. Clark, Carolyn Lou, Fang Liu, Quy Cao, Abigail R. Manning, Melissa L. Martin, Elaina Luskin, Carly M. O’Donnell, Christina J. Azevedo, Peter A. Calabresi, Leorah Freeman, Roland G. Henry, Erin E. Longbrake, Jiwon Oh, Nico Papinutto, Michel Bilello, Jae W. Song, Marwa Kaisey, Nancy L. Sicotte, Daniel S. Reich, Andrew J. Solomon, Daniel Ontaneda, Pascal Sati, Martina Absinta, Matthew K. Schindler, Russell T. Shinohara, and NAIMS Cooperative. Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging, October.

Neurosurgery

Gender Differences in Operative Autonomy Using the Surgical Autonomy Program: A Multicenter Study. Kirsch, Elayna P., Vishal Venkatraman, Di Deng, Katherine E. McDaniel, Alexander D. Suarez, Sean M. Lew, Josiah Orina, Howard Silberstein, Ira Goldstein, Grahame Gould, Chirag D. Gandhi, Chirag Patil, Bradley A. Dengler, Rajeev Dharmapurikar, Shivanand P. Lad, and Michael M. Haglund. Journal of Graduate Medical Education 16 (5): 517–24.

Social Status as a Latent Variable in the Amygdala of Observers of Social Interactions. Lee, SeungHyun, Ueli Rutishauser, and Katalin M. Gothard. Neuron, October, S0896-6273(24)00658-5.

Persistent Activity During Working Memory Maintenance Predicts Long-Term Memory Formation in the Human Hippocampus.  Daume, Jonathan, Jan Kamiński, Yousef Salimpour, Andrea Gómez Palacio Schjetnan, William S. Anderson, Taufik A. Valiante, Adam N. Mamelak, and Ueli Rutishauser. Neuron, October, S0896-6273(24)00661-5.

Additional Diagnostic Value of Cone Beam CT Myelography Performed After Digital Subtraction Myelography for Detecting CSF-Venous Fistulas. Madhavan, Ajay A., Niklas Lutzen, Jeremy K. Cutsforth-Gregory, Wouter I. Schievink, Michelle L. Kodet, Ian T. Mark, Pearse P. Morris, Steven A. Messina, John T. Wald, and Waleed Brinjikji. AJNR. American Journal of Neuroradiology, October, ajnr.A8535.

OBGYN

Short Term Outcomes of Minimally Invasive Total Versus Supracervical Hysterectomy for Uterine Fibroids: A NSQIP Study. Meyer, Raanan, Kacey M. Hamilton, Rebecca Schneyer, Gabriel Levin, Mireille D. Truong, Kelly N. Wright, and Matthew T. Siedhoff. American Journal of Obstetrics and Gynecology, October, S0002-9378(24)01054-8.

Postoperative Outcomes in Minimally Invasive Total Versus Supracervical Hysterectomy for Endometriosis: A NSQIP Study. Meyer, Raanan, Jill McDonnell, Kacey M. Hamilton, Rebecca J. Schneyer, Gabriel Levin, Kelly N. Wright, and Matthew T. Siedhoff. Archives of Gynecology and Obstetrics, October.

Orthopaedics

Comparison of Outcomes for Patients Treated by Allopathic vs Osteopathic Surgeons. Russell, Tara A., Ryu Yoshida, Mauranda Men, Ruixin Li, Melinda Maggard-Gibbons, Christian de Virgilio, Marcia M. Russell, and Yusuke Tsugawa. JAMA Surgery, October.

Pathology and Laboratory Medicine

Rapidly Progressive Primary Cutaneous Gamma Delta T-Cell Lymphoma With FYN Gene Alteration. Azimpouran, Mahzad, Chau M. Bui, Bonnie Balzer, and Sumire Kitahara. The American Journal of Dermatopathology, October.

Pediatrics

Management of Postural Orthostatic Tachycardia Syndrome in Pediatric Patients: A Clinical Review. Huynh, Peter, Alex Brown, Lauren Campisi, Allison Mruk, Tran Nguyen, Mike Raschka, and Titilola Afolabi. The Journal of Pediatric Pharmacology and Therapeutics: JPPT: The Official Journal of PPAG 29 (5): 456–67.

Outcomes of Relapsed Favorable-Histology Wilms Tumor in Non-Clinical Trial Setting.  Schneller, Netta, Najat Daw, Whitney Throckmorton, Elizabeth Mullen, Kylene DeSmith, Leo Mascarenhas, Cameron O’Connell, Conrad V. Fernandez, Kathryn S. Sutton, and Rajkumar Venkatramani. Pediatric Blood & Cancer, October, e31347.

Radiation Oncology

MUsculo-Skeleton-Aware (MUSA) Deep Learning for Anatomically Guided Head-and-Neck CT Deformable Registration. Liu, Hengjie, Elizabeth McKenzie, Di Xu, Qifan Xu, Robert K. Chin, Dan Ruan, and Ke Sheng. Medical Image Analysis 99 (September): 103351.

Development of an EGSnrc Multi-Leaf Collimator Component Module and Treatment Head Model for a Low-Field MRI Linear Accelerator. Etienne, Thomas, Joshua Kim, Kundan Thind, and Indrin J. Chetty. Medical Physics, October.

Surgery

Analgesic Use of Virtual Reality for Burn Dressing Changes in Low- and Middle-Income Countries: A Feasibility Study. Brown, Theodore, Alli Dee, Meghan McCullough, Pedro Santos, and David Kulber. Plastic and Reconstructive Surgery. Global Open 12 (10): e6226.

Predictors of Malignant Transformation in Mucinous Pancreatic Cystic Neoplasm: A Systemic Review and Meta-Analysis. Solis-Pazmino, Paola, Camila Pazmino, Orly Termeie, Kristina La, Eduardo Pilatuna, Belen Tite, Luis Figueroa, Magno Guarconi, Jon Harrison, Yosef Nasseri, Joshua Ellenhorn, and Brendan C. Visser. Surgical Oncology 57 (October): 102153.

Incidence and Outcomes of Pregnant Trauma Patients With Positive Urine Toxicology: A Southern California Multicenter Study. Clark, Isabel, Jeffry Nahmias, Mallory Jebbia, Negaar Aryan, Alexa N. Lucas, Nicole Fierro, Navpreet K. Dhillon, Eric J. Ley, Jennifer Smith, Sigrid Burruss, Alden Dahan, Arianne Johnson, William Ganske, Walter L. Biffl, Dunya Bayat, Matthew Castelo, Diane Wintz, Kathryn B. Schaffer, Dennis J. Zheng, Areti Tillou, Raul Coimbra, Rahul Tuli, Jarrett E. Santorelli, Brent Emigh, Morgan Schellenberg, Kenji Inaba, Thomas K. Duncan, Graal Diaz, Erika Tay-Lasso, Danielle C. Zezoff, and Areg Grigorian. The American Surgeon, October, 31348241290612.

Staged Nipple Delay Procedure Expands Candidacy for Nipple-Sparing Mastectomy. Wang, Xuanji, Jordan Jackson, Christina Weed, Marissa K. Boyle, Farin F. Amersi, James Mirocha, Armando E. Giuliano, and Alice P. Chung. Annals of Surgical Oncology, October.

Presentation and Optimal Management of Anterior and Central Skull Base Osteoradionecrosis: Systematic Review and Meta-Analysis. Shah, Sunny R., Arthur Wu, Raj Sindwani, and Dennis Tang. The Laryngoscope, October.