Faculty Publications Nov. 6-13
A Comprehensive Digest of Research Publications From Cedars-Sinai Investigators and a Sampling of Recent Media Coverage Featuring Faculty
This week’s edition of Faculty Publications includes Cedars-Sinai studies that were published Nov. 6-13. If you have a published paper from this period that does not appear on this list, please contact Sue Marone.
Cedars-Sinai in the News
Video: An Interview With Dr. Chikwe | Cardiology Advisor
Joanna Chikwe, MD
Stopping DOACs After Successful AF Ablation Feasible In Low-Risk Patients: OCEAN | TCTMD
Christine Albert, MD, MPH
The Asher Series Survivorship and Beyond Presented by Oncodaily LA | Oncodaily
Arash Asher, MD
How Does Gravity Harm Health? | European Medical Journal
Brennan Spiegel, MD
The Rise of AI in Healthcare Shows Both Progress and Roadblocks | Managed Healthcare Executive
Elias Aboujaoude, MD
Scientists Just Found a Shockingly Easy Way to Shield Your Brain From Alzheimer’s. And It’s Totally Free | Men’s Health
Vernon Williams, MD
How Health Systems Can Build an AI-Ready Data Infrastructure | TechTarget
Mouneer Odeh, MA
Faculty Publications
Anesthesiology
1-Year Outcomes After Transcatheter Edge-to-Edge Repair in Degenerative MR Stratified by Extent of Cardiac Damage. Al-Abcha, Abdullah, D. Scott Lim, Jörg Hausleiter, Robert L. Smith, Firas Zahr, Scott Chadderdon, Raj Makkar, Moody M. Makar, Ralph Stephan von Bardeleben, Tobias Friedrich Ruf, Theresa Gößler, Robert M. Kipperman, Andrew N. Rassi, Ivy A. Ku, Michael Nabauer, Molly Szerlip, Zuyue Wang, Scott Goldman, Katie M. Hawthorne, Konstantinos Koulogiannis, Leo Marcoff, Linda D. Gillam, Mayra E. Guerrero, and CLASP IID Pivotal Trial Investigators. JACC. Cardiovascular Interventions 18 (21): 2596–2611.
Biomedical Sciences
The Effect of Group Singing Interventions on Health Biomarkers in People With Stigmatising Conditions: A Scoping Review Protocol. Bouguettaya, Ayoub, Kylie Reeves, Phoebe Tat, and Judy Y. Tan. Systematic Reviews 14 (1): 217.
Cardiology
Reducing Inequalities in Cardiovascular Disease: Focus on Marginalized Populations Considering Ethnicity and Race. Anand, Sonia S., Sujane Kandasamy, Miles Marchand, Maryam Kavousi, Martha Gulati, John Deanfield, and Arshed A. Quyyumi. The Lancet Regional Health. Europe 56 (September): 101371.
Novel Technique to Optimize Extravascular Implantable Cardioverter-Defibrillator Implantation With the Use of a Video-Assisted Thoracoscopic Epicardial Access Tool. Ehdaie, Ashkan, Jessica Mao, Archana Ramireddy, Eric Braunstein, Eugenio Cingolani, Michael Shehata, Xunzhang Wang, and Raymond Schaerf. Heart Rhythm, October, S1547-5271(25)02978-9.
From Silence to Storm: Plexin Signaling as a Therapeutic Crossroad. Liu, Xiao, and Peng-Sheng Chen. JACC. Clinical Electrophysiology, October, S2405-500X(25)00801-1.
Special Issue ‘Molecular Advances in Heart Disease: Genomics, Proteomics, and Bioinformatics of Heart Research.’ Fert-Bober, Justyna. International Journal of Molecular Sciences 26 (21): 10492.
A Cross-Sectional Comparison of Invasive and Noninvasive Aortic Pulse Wave Velocity Measurement in Patients With or at Risk for Heart Failure With Preserved Ejection Fraction. Asif, Anum, Michael D. Nelson, Chrisandra Shufelt, T. Jake Samuel, Galen Cook-Wiens, Judy Luu, Benita Tjoe, Balaji Tamarappoo, Daniel S. Berman, C. Noel Bairey Merz, and Janet Wei. Cardiovascular Diagnosis and Therapy 15 (5): 1012–19.
Beyond Body Mass Index in Heart Transplantation: More Than Meets the Eye. Nguyen, Ann B., and Michelle Kittleson. JACC: Heart Failure, November, 102764.
Opportunistic AI-Derived Adiposity Measures From Coronary Artery Calcium Scans Predict New-Onset Type 2 Diabetes in Adults Without Obesity or Hyperglycemia: Insights From the AI-CVD Study Within MESA. Naghavi, Morteza, Amir Azimi, Kyle Atlas, Anthony P. Reeves, Chenyu Zhang, Jakob Wasserthal, Seyed Reza Mirjalili, Mohammadhossein Mozafarybazargany, Ali Hashemi, Thomas Atlas, Claudia I. Henschke, David F. Yankelevitz, Jeffrey I. Mechanick, Andrea D. Branch, Susan K. Fried, Khurram Nasir, Zahi A. Fayad, Michael V. McConnell, Rozemarijn Vliegenthart, David J. Maron, Jagat Narula, Kim A. Williams, Prediman K. Shah, Matthew J. Budoff, Daniel Levy, Emelia J. Benjamin, Robert A. Kloner, and Nathan D. Wong. Diabetology & Metabolic Syndrome 17 (1): 419.
Efficacy of Acoramidis in Wild-Type and Variant Transthyretin Amyloid Cardiomyopathy: Results From ATTRibute-CM and Its Open-Label Extension. Alexander, Kevin M., Margot K. Davis, Olakunle Akinboboye, John Berk, Kunal Bhatt, Francesco Cappelli, Sarah A. M. Cuddy, Marianna Fontana, Pablo Garcia-Pavia, Julian D. Gillmore, Jan M. Griffin, Justin L. Grodin, Daniel P. Judge, Michel G. Khouri, Kaitlyn Lam, Ahmad Masri, Mathew S. Maurer, Laura Obici, Frederick L. Ruberg, Nitasha Sarswat, Keyur Shah, Prem Soman, Lily Stern, Richard Wright, Kuangnan Xiong, Xiaofan Cao, Ted Lystig, Jean-François Tamby, Adam Castaño, Leonid Katz, Uma Sinha, Jonathan C. Fox, Scott D. Solomon, and Martha Grogan. JAMA Cardiology, November, e254477.
Comprehensive Echocardiogram Evaluation With View Primed Vision Language AI. Vukadinovic, Milos, I.-Min Chiu, Xiu Tang, Neal Yuan, Tien-Yu Chen, Paul Cheng, Debiao Li, Susan Cheng, Bryan He, and David Ouyang. Nature, November.
Computational Biomedicine
Evaluating Breast Cancer Screening Consortium and MammoRisk Plus Polygenic Risk Score 313 for Breast Cancer Risk Prediction in UK Biobank. Rassy, Elie, Suzette Delaloge, Mojgan Karimi, Thérèse Truong, Emilien Gauthier, Stéphane Ragusa, Damien Drubay, Paul Pharoah, Stefan Michiels, and Maryam Karimi. European Journal of Cancer (Oxford, England: 1990) 231 (November): 116096.
Detecting Transthyretin Cardiac Amyloidosis With Artificial Intelligence: A Nonrandomized Clinical Trial. Jain, Sneha S., Tony Sun, Emma Pierson, Francisco Roedan Oliver, Paloma Malta, Michelle Castillo, Ningxin Wan, Shudhanshu Alishetti, Heidi Hartman, Joshua Finer, Kathleen L. Brown, Vijendra Ramlall, Nicholas Tatonetti, Noémie Elhadad, Fatima Rodriguez, Ronald Witteles, Parag Goyal, Shunichi Homma, Andrew J. Einstein, Mathew S. Maurer, Pierre Elias, and Timothy J. Poterucha. JAMA Cardiology, November, e254591.
Medicine
Efficacy and Safety of Glucagon-Like Peptide-1 Receptor Agonists for Obesity Management in Adults With and Without Type 2 Diabetes: A Systematic Review. Velji-Ibrahim, Jena, Dhruvil Radadiya, Kalpit Devani, Harsh Patel, Piyush Nathani, Cesare Hassan, Nicola Pugliese, Christopher Thompson, and Prateek Sharma. Journal of Obesity 2025: 3897161.
Epcoritamab Plus Gemcitabine and Oxaliplatin Versus Rituximab Plus Gemcitabine and Oxaliplatin in Transplant-Ineligible Relapsed/Refractory Diffuse Large B-Cell Lymphoma: A Match-Adjusted Comparative Analysis. Munoz, Javier, Allison Rosenthal, Andrew Ip, Justin M. Darrah, Tongsheng Wang, Guihua Zhang, Alex Mutebi, Tychell Branchcomb, Zhijie Ding, Anindit Chhibber, Fernando Rivas Navarro, Malene Risum, Mohammad Atiya, Samantha Brodkin, Anthony Wang, Abualbishr Alshreef, Diala Harb, Mariana Sacchi, Daniela Hoehn, and Yasmin H. Karimi. Clinical Lymphoma, Myeloma & Leukemia, October, S2152-2650(25)04247-8.
IgG N-Glycan Profiles in Mothers and Infants Postpartum in the Context of Maternal Obesity and Gestational Diabetes. Farkas, Anna, Oksana Matsyura, Lesya Besh, Andras Guttman, and Sandor G. Vari. International Journal of Molecular Sciences 26 (21): 10641.
From Fibroblast Foci to Dense Scars: PAK2-Activated Fibroblasts Drive Fibrosis Progression in Idiopathic Pulmonary Fibrosis. Zhang, Xuexi, Xue Liu, and Paul W. Noble. The European Respiratory Journal 66 (5): 2501549.
The Expanding Landscape of Next-Generation EGFR Tyrosine Kinase Inhibitors: Have We Reached Capacity? Sankar, Kamya, Barliz Waissengrin, and Karen L. Reckamp. Journal of Thoracic Oncology 20 (11): 1569–72.
Lessons Learned From Physician-Performed High-Resolution Esophageal Manometries. Wongjarupong, Nicha, Ali Rezaie, Mark Pimentel, Bianca W. Chang, Yin Chan, Jane E. Lim, Alice C. Huang, and Amrit K. Kamboj. Diseases of the Esophagus 38 (6): doaf094.
Selective Inhibition of Long Isoforms of Phosphodiesterase 4D Mitigates Liver Fibrosis in Mouse Models. Kim, Jeonghan, Heeeun Yoon, Seoung Chan Joe, Antoine Smith, Jinsung Park, Geunhye Hong, Ji Myeong Ha, Eun Bae Kim, Ekihiro Seki, Myung K. Kim, Hae-Ock Lee, Ho-Shik Kim, and Jay H. Chung. The Journal of Clinical Investigation, November, e182571.
Trends in Concurrent Psychiatric Comorbidities in Alcohol-Associated Liver Disease: A Nationwide Study from 2015-2023. Chan, Shu-Yen, Yee Hui Yeo, Hyunseok Kim, Molly Delk, Natchaya Polpichai, Pojsakorn Danpanichkul, and Peng-Sheng Ting. Digestive Diseases and Sciences, November.
Impact of Statins on Progression of Coronary Artery Calcium Composition and Density as Assessed by Noncontrast CT. Giovannucci, Julian, Aakash Shanbhag, Wei Hong, Yuanqi Yong, Sow Neng Pang, Seamus Heanue, Anawar Maung, Katherine Tsigaridis, Rohullah Sultani, Kyrillos Kaleeny, Robert Jh Miller, Donghee Han, Daniel S. Berman, Michelle C. Williams, Damini Dey, Stephen J. Nicholls, Piotr J. Slomka, Nitesh Nerlekar, and Andrew Lin. The International Journal of Cardiovascular Imaging, November.
Racial and Ethnic Disparities in Pandemic-Onset Disorders of Gut-Brain Interaction: Results From a Nationwide Survey. Yang, Yixin, Brennan M. R. Spiegel, William D. Chey, So Yung Choi, and Christopher V. Almario. Neurogastroenterology and Motility, November, e70200.
Taste Disorders in Cancer Patients and Current Therapeutic Approaches: A Narrative Review of an Understudied Topic in Supportive Care. Barasch, Andrei, and Joel B. Epstein. Supportive Care in Cancer 33 (12): 1024.
TH17 Cells Converted Into exTH17 Cells Sustain Rheumatoid-like IL-17-Independent Inflammatory Arthritis. Zoccheddu, Martina, Kensuke Suga, Amara Seng, Mattias N. D. Svensson, Paramita Dutta, Sanaz Panahandeh, Hadijat-Kubura Moradeke Makinde, Myungja Ro, Yizhou Wang, Hyobin Kim, Zbigniew Mikulski, Katarzyna Dobaczewska, Francesca Ingegnoli, Ruth Minsha, John F. Seagrist, Mary Carns, Kathleen Aren, Salina Dominguez, Mohammad Daud Khan, Angela Denn, Roberto Caporali, Pietro Simone Randelli, David A. McBride, Arthur M. Mandelin, Carla Marie Cuda, Zhiping Paul Wang, Jason H. Moore, Nisarg J. Shah, Kyoung Jae Won, Deborah R. Winter, Ferhat Ay, Harris Perlman, and Nunzio Bottini. Science Immunology 10 (113): eadm7800.
Age- and Sex-Specific Lipoprotein Profiles in General and Cardiometabolic Population Cohorts. Conde, Ricardo, Rubén Gil-Redondo, Maider Bizkarguenaga, Samantha Lodge, Phillip Nitschke, Ángela de Diego, Beatriz González-Valle, Jennie Hui, Michael L. Hunter, Bu B. Yeap, Ana Cenarro, Virginia Lope, Hansjörg Habisch, Christoph Haudum, Nicolas Verheyen, Barbara Obermayer-Pietsch, María José Zaro Bastanzuri, María Reyes González Fernández, Daniel Fernández-Bergés, Ane Miren Salazar, Maria Pilar Sorando-Fernandez, Susana Meijide, Gonzalo Hernandez, Eunate Arana, Maria Luisa Seco, Adriana Sousa, Nádia Oliveira, Ignacio Verde, Tobias Madl, Miguel Unda-Urzaiz, Arkaitz Carracedo, Tammo Diercks, Adela Castelló, Hartmut Schäfer, Manfred Spraul, Claire Cannet, Nieves Embade, Luca Valenti, Fernando Civeira, Shelly C. Lu, Elaine Holmes, Julien Wist, Jeremy K. Nicholson, José M. Mato, and Oscar Millet. EBioMedicine 122 (November): 106021.
Genetic Susceptibility and Validation of Angiographic Patterns in Takayasu Arteritis. Casares-Marfil, Desiré, K. Bates Gribbons, Guher Saruhan-Direskeneli, Sema Kaymaz-Tahra, Kaitlin A. Quinn, Fatma Alibaz-Oner, Peter C. Grayson, Haner Direskeneli, Amr H. Sawalha, Peter A. Merkel, and Turkish Takayasu Arteritis Study Group and the Vasculitis Clinical Research Consortium. Journal of Autoimmunity 157 (November): 103496.
Reply to Correspondence to ‘Predictive Machine Learning Model in Intensive Care Unit Patients With Acute-on-Chronic Liver Failure and Two or More Organ Failures.’ Zhang, Mengyi, Yee Hui Yeo, Jian Zu, Jonel Trebicka, and Fanpu Ji. Clinical and Molecular Hepatology, November.
Real-World Treatment Patterns and Clinical Outcomes in Patients With Extensive-Stage Small Cell Lung Cancer Treated With First-Line Platinum-Based Chemotherapy and ≥ 2 Subsequent Lines of Therapy in the United States. Sankar, Kamya, Sudhir Unni, Marian Eberl, Hoa Le, Tara Herrmann, Boris Gorsh, Mei Tang, Friso Coerts, and Sajid Ahmed. Advances in Therapy, November.
Provider Perceptions and Insights on Polygenic Risk Scores for Colorectal Cancer: A Qualitative Study. Esmundo, Shenazar, Nenette Caceres, Charité Ricker, Gregory E. Idos, Nicole C. Loroña, Yelba Castellon-Lopez, Stephanie L. Schmit, Cathy D. Meade, Clement K. Gwede, Nathalie T. Nguyen, and Jane C. Figueiredo. Journal of Genetic Counseling 34 (6): e70135.
Neurosurgery
Utility of Combining Frailty and Comorbid Disease Indices to Better Predict Outcomes Following Craniotomy for Pediatric Primary Brain Tumors. Nguyen, Alan, Michelot Michel, Shane Shahrestani, Andre Boyke, Catherine M. Garcia, Simon Menaker, Moise Danielpour, and David Bonda. Pediatric Neurosurgery, October, 1–9.
Abdominal Pseudocyst Post Ventriculoperitoneal Shunt: A Systematic Review. Almahrouqi, Omar, Juhaina Al Raisi, Eman Almusilhi, Reema Al Majarafi, Baraea Al-Farsi, Malak Al Ismaili, and Tariq D. Al-Saadi. Neurology India 73 (6): 1134–40.
OBGYN
Postcesarean Delivery Use of a Modified FAST (Focused Assessment With Sonography for Trauma) Examination. Treacy, Laura, Rachel Newman, Naomi Greene, and Kimberly Gregory. Obstetrics and Gynecology, November.
Orthopaedics
Prediction of Short-Term Postoperative Complications Following Open Reduction Internal Fixation of Ankle Fractures. Agarwalla, Avinesh, Anirudh K. Gowd, Elizabeth A. Cody, Eric W. Tan, Alexander B. Peterson, and Joseph N. Liu. The Journal of the American Academy of Orthopaedic Surgeons, October.
Intramedullary Nail Fixation of Operative Tibia Fractures Distal to a Total Knee Arthroplasty. Metcalf, Kathryn, Mir Ibrahim Sajid, Meghan McCaskey, Brian Johnson, Michael Beltran, Margaret Sinkler, George Ochenjele, Roman Natoli, Jan Szatkowski, Mackinzie Stanley, Milton Little, and Hassan R. Mir. European Journal of Orthopaedic Surgery & Traumatology: Orthopedie Traumatologie 36 (1): 11.
Pathology and Laboratory Medicine
Impaired Kidney Function With Kidney Tubular Vacuolization and Crystals in Adult Refsum Disease: A Case Report. Lee, Chen Yu Jamie, Mark D. Elliott, Anna Lehman, Myriam Farah, Susanna A. McRae, and Maziar Riazy. Kidney Medicine 7 (11): 101107.
Neoadjuvant Antiandrogen Therapy With or Without MEK or SRC Inhibition for Unfavorable-Risk Prostate Cancer: A Phase 2 Randomized Clinical Trial. Agrawal, Raag, Adam B. Weiner, Julie Livingstone, Aydin Pooli, Rong Rong Huang, Huihui Ye, Anthony Sisk, David A. Elashoff, Paul C. Boutros, Matthew B. Rettig, and Robert E. Reiter. European Urology Oncology, November, S2588-9311(25)00287-1.
Visit-to-Visit Blood Pressure Variability and Dementia Risk After Considering Antihypertensive Treatment: Real-World Data From the Japanese National Health Insurance. Satoh, Michihiro, Hiroki Nobayashi, Shingo Nakayama, Yutaro Iwabe, Takahito Yagihashi, Seiya Izumi, Takahisa Murakami, Yuya Suzuki, Maya Toyama, Tomoko Muroya, Takayoshi Ohkubo, and Hirohito Metoki. Hypertension Research, November.
Pediatrics
Editorial: Phenotypic Transitions and Endothelial Dysfunction in Cardiovascular Diseases: Mechanisms, Therapeutic Targets, and Modulation. Pernomian, Laena, Vanessa de Fátima Borges, Gerson Jhonatan Rodrigues, and Cristina Espinosa-Diez. Frontiers in Physiology 16: 1720883.
Risk Factors for Loss of Varicella Immunity After Pediatric Kidney Transplantation. Pizzo, Helen, Priya R. Soni, Santhosh Nadipuram, James Mirocha, Jonathan Garrison, Sherlyn Hilario, and Dechu Puliyanda. Pediatric Nephrology (Berlin, Germany), November.
Radiation Oncology
The Potential of (177Lu)-PSMA-617 in the First-Line Combination Therapy With Enzalutamide for Metastatic Castration-Resistant Prostate Cancer: Clinical Insights From the ENZA-p Trial. Zheng, Renning, Stephen J. Freedland, and Anthony T. Nguyen. Chinese Clinical Oncology 14 (5): 63.
Trends in Prostate Brachytherapy Utilization in The United States and Implications for Resident Training: Prostate Brachytherapy and Resident Training. Isaac, Evrosina I., Mustafa Basree, Peter F. Orio, Catheryn M. Yashar, and Mitchell Kamrava. Practical Radiation Oncology, November, S1879-8500(25)00260-7.
Reply to Dedeepya et al. Comment on ‘High-Dose-Rate (HDR) Brachytherapy Boost in Combination With External Beam Radiotherapy for Localized Prostate Cancer.’ Patel, Sagar A., and Mitchell R. Kamrava. Brachytherapy, November, S1538-4721(25)00320-4.
Surgery
Outcomes From Referral to Transplant for Patients With MASLD: A California Liver Network Study. Lim, Tiffany Y., Justin A. Steggerda, Hirsh Trivedi, Michael Luu, Aarshi Vipani, Michie A. Adjei, Jasleen Singh, Kali Zhou, Allison Kwong, Monica Tincopa, Irine Vodkin, Veeral Ajmera, Neil Mehta, Chris E. Freise, Mignote Yilma, Ryutaro Hirose, Alexander Kuo, and Steven A. Wisel. Journal of Clinical Medicine 14 (21): 7841.
Surgical Oncologists for Sustainability: A Statement From the SSO Surgical Oncologists for Sustainability Committee. Gabriel, Emmanuel M., Kathryn T. Chen, Miral Amin, Rebecca Ann Craufurd Auer, Ricardo Julio Bello, Russell S. Berman, Pam Hayden, Kayleigh Herrick-Reynolds, Tari A. King, Ioannis T. Konstantinidis, Kayla Laraia, Gary N. Mann, Corbin Morris, Colette Pameijer, Ranjna Sharma, Georgios Tsoulfas, Jaeyun Jane Wang, and E. Shelley Hwang. Annals of Surgical Oncology, November.
Buccal Fat Pad Modification in Aesthetic Facial Surgery. Wang, Lexie Lulu, and Babak Azizzadeh. Facial Plastic Surgery Clinics of North America 34 (1): 51–54.
Comprehensive Midface and Periorbital Rejuvenation. Azizzadeh, Babak. Facial Plastic Surgery Clinics of North America 34 (1): xv–xvi.
Extended Deep Plane Facelift and Structural Neck Contouring: Technical Considerations for Comprehensive Surgical Facial Rejuvenation. VandeWater, Tracy, and Babak Azizzadeh. Facial Plastic Surgery Clinics of North America 34 (1): 1–16.
Urology
Vaginal Mesh Exposure After Single-Incision vs Full-Length Midurethral Sling Placement: A Retrospective Cohort Study. Kirschenbaum, Matthew P., Rachel Caskey, and Karyn S. Eilber. International Urogynecology Journal, November.
ONECUT2: A Validated Drug Target and Lineage Plasticity Driver in Prostate Cancer and Other Malignancies. Freeman, Michael R., Lillian M. Perez, Qian Yang, Chen Qian, Ramachandran Murali, Mirja Rotinen, Edwin M. Posadas, Dolores Di Vizio, Stephen J. Freedland, and Sungyong You. Endocrine-Related Cancer, November, ERC-25-0272.
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