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May
2025
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Faculty Publications May 15-22

A Comprehensive Digest of Research Publications From Cedars-Sinai Investigators and a Sampling of Recent Media Coverage Featuring Faculty

This week’s edition of Faculty Publications includes Cedars-Sinai studies that were published May 15-22. If you have a published paper from this period that does not appear on this list, please contact Sue Marone.

 

Cedars-Sinai in the News

How Doctors Treat Aggressive Prostate Cancer Like Joe Biden’s | TIME
Robert Figlin, MD

Cancer Diagnosis And a New Book Fuel Questions About Biden’s Decision to Run in 2024 | Los Angeles Times
Howard Sandler, MD 

Biden's Cancer Diagnosis Raises Fresh Questions About His Health in White House | BBC
Robert Figlin, MD 

Is Bleeding During Pregnancy Normal? Here’s What to Know | Self
Mariam Naqvi, MD

This 1 Hobby Is Great For An Aging Brain, According To A New Study | HuffPost
Golnaz Yadollahikhales, MD

How Cedars-Sinai Is Using AI to Reduce Pregnancy-Related Health Risks | BlackDoctor 
Melissa Wong, MD

Proven Stress Management Techniques to Maintain a Healthy Heart | Flow Space
Martha Gulati, MD

Who Needs More Exercise: Women or Men? | Live Science
Martha Gulati, MD; Christine Albert, MD, MPH

Virtual Reality Enhances Patients’ Comfort During OB/GYN Procedures | Medscape
Melissa Wong, MD

 

Faculty Publications

Biomedical Sciences

Language Justice as an Antiracism Institutional Transformation: Institutional Facilitators and Barriers for Community-Engaged Cardiometabolic Health Promotion Research. LeBrón, Alana M. W., Yelba M. Castellon-Lopez, Melody Gonzalez, Julia Mangione, Pamela Pimentel, Aziza Lucas-Wright, Mary Anne Foo, Audrey Kawaiopua Alo, Krystal Lloyd, Dara H. Sorkin, Bernadette Boden-Albala, Keith Norris, Arleen Brown, Sora Park Tanjasiri, and Mona AuYoung. Journal of Clinical and Translational Science 9 (1): e73.

Effect of Low-Dose Colchicine on Pericoronary Inflammation and Coronary Plaque Composition in Chronic Coronary Disease: A Subanalysis of the LoDoCo2 Trial. Fiolet, Aernoud T. L., Andrew Lin, Jacek Kwiecinski, Julie Tutein Nolthenius, Priscilla McElhinney, Kajetan Grodecki, Bas Kietselaer, Tjerk S. Opstal, Jan Hein Cornel, Remco Jj Knol, Jeroen Schaap, Ruud A. H. M. Aarts, Annemieke M. F. A. Tutein Nolthenius, Stefan M. Nidorf, Birgitta K. Velthuis, Damini Dey, and Arend Mosterd. Heart, May, heartjnl-2024-325527.

Deep Learning With Domain Randomization in Image and Feature Spaces for Abdominal Multiorgan Segmentation on CT and MRI Scans. Shi, Yu, Lixia Wang, Touseef Ahmad Qureshi, Zengtian Deng, Yibin Xie, and Debiao Li. Radiology. Artificial Intelligence, May, e240586.

Accelerating CEST MRI With Deep Learning-Based Frequency Selection and Parameter Estimation. Shen, Chushu, Karandeep Cheema, Yibin Xie, Dan Ruan, and Debiao Li. NMR in Biomedicine 38 (7): e70068.

Cardiology

Who Is the Candidate? The Heart Transplant Evaluation Process. Kittleson, Michelle M. Methodist DeBakey Cardiovascular Journal 21 (3): 13–24.

Non-Calcified Coronary Plaque Burden Is Related to Epicardial Adipose Tissue and Peri-Coronary Adipose Tissue Attenuation in Heart Failure With Preserved Ejection Fraction. Iribarren, Ana C., Haider Aldiwani, Panteja Rezaeian, Alan C. Kwan, Varun Pattisapu, Galen Cook-Wiens, Jenna Maughan, Chrisandra Shufelt, Louise Elizabeth Jane Thompson, Balaji Tamaroppoo, Daniel Berman, Damini Dey, C. Noel Bairey Merz, and Janet Wei. International Journal of Heart Failure 7 (2): 116–20.

Antecedent Flu-Like Illness and Onset of Idiopathic Dilated Cardiomyopathy: The DCM Precision Medicine Study. Ni, Hanyu, Jinwen Cao, Daniel D. Kinnamon, Elizabeth Jordan, Garrie J. Haas, Mark Hofmeyer, Evan P. Kransdorf, Jamie Diamond, Anjali Owens, Brian Lowes, Douglas Stoller, W. H. Wilson Tang, Mark H. Drazner, Palak Shah, Jane E. Wilcox, Stuart D. Katz, Javier Jimenez, Supriya Shore, Daniel P. Judge, Jonathan O. Mead, Jason Cowan, Patricia K. Parker, Gordon S. Huggins, and Ray E. Hershberger. Circulation. Heart Failure 18 (5): e012602.

Deep Learning on Electrocardiogram Waveforms to Stratify Risk of Obstructive Stable Coronary Artery Disease. Trivedi, Rishi K., I. Min Chiu, John Weston Hughes, Albert J. Rogers, and David Ouyang. European Heart Journal. Digital Health 6 (3): 456–65.

Epidemiology of Valvular Heart Disease in Asia Pacific Region. So, Kent Chak-Yu, Jonathan Yap, Guang-Yuan Song, Karl Poon, Shih-Hsien Sung, Mann Chandavimol, Kentaro Hayashida, Duk-Woo Park, See-Hooi Ewe, Mi Chen, Vyanne Hei-Tung Chan, Juri Iwata, Tarinee Tangcharoen, Paul Tern, Han-Su Park, Mirvat Alasnag, Yohei Ohno, Jimmy Kim Fatt Hon, Rohan Bhagwandeen, Minoru Tabata, Alex Pui-Wai Lee, Hasan Jilaihawi, Dee Dee Wang, Gilbert H. L. Tang, D. Scott Lim, Thomas Modine, and Yat-Yin Lam. JACC. Asia, May, S2772-3747(25)00224-8.

Recommendations to Overcome Barriers to Transplant Fellowship Training: A Report from the American Society of Transplantation Fellows Task Force. Kobashigawa, Jon, Josh Levitsky, Neeraj Singh, Kiran Khush, Sean Pinney, Elizabeth Aby, Aasim Afzal, Deborah Adey, Anshul Bhalla, Mona Doshi, Samira Farouk, Alyson Fox, Shelley Hall, Michelle Kittleson, Lindsay King, Alexander Kuo, Deborah Levine, Yosef Manla, Jamak Modaresi, Arjmand Mufti, Prince Mohan Anand, Michael Nurok, Jp Norvell, Neehar Parikh, Anjana Pillai, Faruq Pradhan, Allison Ramsey, Milagros Samaniego-Picota, Ishna Poojary-Hohman, Manpreet Samra, Deirdre Sawinski, Kelly Schlendorf, Stuart Sweet, Bekir Tanriover, Sarthak Virmani, and Roy D. Bloom. American Journal of Transplantation, May, S1600-6135(25)00261-8.

Ratio of Interventricular Septal Thickness to Global Longitudinal Strain Accurately Identifies Cardiac Amyloidosis. Cao, Louie, Gloria J. Hong, Michael Abiragi, Jonathan Le, P. Ryan Tacon, I.-Min Chiu, Jignesh Patel, Lily K. Stern, Chathuri Daluwatte, David Ouyang, and Piero Ricchiuto. Open Heart 12 (1): e003120.

Sex Differences in the Impact of Exercise Volume on Subclinical Coronary Atherosclerosis: A Meta-Analysis. Abdelaziz, Ahmed, Ahmed Elshahat, Ahmed Farid Gadelmawla, Muhammad Desouky, Abdelrahman H. Hafez, Mohamed Abdelaziz, Noha Hammad, Dua Eldosoky, Kirtipal Bhatia, Annalisa Filtz, Daniel Lorenzatti, Toshiki Kuno, Salim S. Virani, Martha Gulati, Michel D. Shapiro, Carl J. Lavie, and Leandro Slipczuk. JACC. Advances 4 (6 Pt 1): 101786.

Improving Cardiovascular Clinical Competencies for the Menopausal Transition: A Focus on Cardiometabolic Health in Midlife. Dastmalchi, Lily N., Martha Gulati, Rebecca C. Thurston, Emily Lau, Amy Sarma, Cherie Q. Marfori, Allison E. Gaffey, Stephanie Faubion, Deepika Laddu, Chrisandra L. Shufelt, and Garima Sharma. JACC. Advances, May, 101791.

Arteries and Hearts in Motion: Sex Differences in Exercise-Mediated Protection Against Atherosclerotic Cardiovascular Disease Risk. Clayton, Zachary S., Mackenzie N. Kehmeier, Ryan Rosenberry, Emily A. Larson, Amélie Debray, Susan Cheng, and Kerrie L. Moreau. Current Atherosclerosis Reports 27 (1): 56.

Large Language Model Comparisons between English and Chinese Query Performance for Cardiovascular Prevention. Ji, Hongwei, Xiaofei Wang, Ching-Hui Sia, Jonathan Yap, Soo Teik Lim, Andie Hartanto Djohan, Yaowei Chang, Ning Zhang, Mengqi Guo, Fuhai Li, Zhi Wei Lim, Ya Xing Wang, Bin Sheng, Tien Yin Wong, Susan Cheng, Khung Keong Yeo, and Yih-Chung Tham. Communications Medicine 5 (1): 177.

Validation of a Novel Risk Prediction Score for Sudden Cardiac Death in the Framingham Heart Study. Truyen, Thien Tan Tri Tai, Honghuang Lin, Marco Mathias, Harpriya Chugh, Kyndaron Reinier, Emelia J. Benjamin, and Sumeet S. Chugh. Circulation. Arrhythmia and Electrophysiology, May, e013647.

Refractory Angina in Women With Ischemia and No Obstructive Coronary Artery Disease - A Report from the Women’s Ischemia Syndrome Evaluation-Coronary Vascular Dysfunction (WISE-CVD) Study. Luu, Judy M., Janet Wei, Chrisandra Shufelt, Anum Asif, Benita Tjoe, Galen Cook-Wiens, Eileen M. Handberg, Puja K. Mehta, Jenna Maughan, Daniel S. Berman, Louise E. J. Thomson, Carl J. Pepine, and C. Noel Bairey Merz. American Heart Journal Plus: Cardiology Research and Practice 54 (June): 100547.

Computational Biomedicine

Biomedical Text Normalization Through Generative Modeling. Berkowitz, Jacob S., Apoorva Srinivasan, Jose Miguel Acitores Cortina, Yasaman Fatapour, and Nicholas P. Tatonetti. Journal of Biomedical Informatics, May, 104850.

Imaging

The Role of Ferumoxytol-Enhanced MR Venography in Transvenous Embolization of Cerebrospinal Fluid-Venous Fistulas. Galvan, Javier L., Theodore W. Hagens, Rola Saouaf, Wouter I. Schievink, and Marcel M. Maya. AJNR. American Journal of Neuroradiology, May, ajnr.A8837.

Medicine

Postdischarge Alcohol Cessation and Psychiatric Referrals in Alcoholic Liver Disease. Chan, Shu-Yen, Yee Hui Yeo, Hyunseok Kim, Natchaya Polpichai, Yueh-Ting Tsai, and Peng-Sheng Ting. JAMA Network Open 8 (5): e2511619. 

Plain Language Summary of MARIPOSA-2: Amivantamab-Chemotherapy Either With or Without Lazertinib for Treatment of Non-Small-Cell Lung Cancer. Passaro, Antonio, Alexis B. Cortot, Ryan D. Gentzler, Karen L. Reckamp, Sujay Shah, William Nassib William, and Byoung Chul Cho. Future Oncology (London, England), May, 1–16.

AI-Based Volumetric Six-Tissue Body Composition Quantification from CT Cardiac Attenuation Scans for Mortality Prediction: A Multicentre Study. Yi, Jirong, Anna M. Marcinkiewicz, Aakash Shanbhag, Robert J. H. Miller, Jolien Geers, Wenhao Zhang, Aditya Killekar, Nipun Manral, Mark Lemley, Mikolaj Buchwald, Jacek Kwiecinski, Jianhang Zhou, Paul B. Kavanagh, Joanna X. Liang, Valerie Builoff, Terrence D. Ruddy, Andrew J. Einstein, Attila Feher, Edward J. Miller, Albert J. Sinusas, Daniel S. Berman, Damini Dey, and Piotr J. Slomka. The Lancet. Digital Health, May, 100862.

Utilization and Outcomes of Mohs Micrographic Surgery Versus Wide Local Excision in Sebaceous Carcinoma: A Retrospective Cohort Analysis. Zhou, Maggie H., Vijay Kodumudi, Nima Gharavi, and Amanda Rosenthal. Journal of the American Academy of Dermatology, May, S0190-9622(25)02117-6.

An Evaluation of Patritumab Deruxtecan for the Treatment of EGFR-Mutated Non-Small Cell Lung Cancer. Waissengrin, Barliz, and Karen L. Reckamp. Expert Opinion on Biological Therapy, May.

Perioperative Management of Patients Taking Glucagon-like Peptide 1 Receptor Agonists: Society for Perioperative Assessment and Quality Improvement (SPAQI) Multidisciplinary Consensus Statement. Oprea, Adriana D., Laura J. Ostapenko, BobbieJean Sweitzer, Angela Selzer, Joan M. Irizarry-Alvarado, Maria D. Hurtado Andrade, Carlos E. Mendez, Kristen D. Kelley, Erin Stewart, Claudia R. Fernandez Robles, Ryan M. Chadha, Michael Camilleri, Ruchi Mathur, Guillermo E. Umpierrez, and David L. Hepner. British Journal of Anaesthesia, May, S0007-0912(25)00214-4.

How I Do It: Best Practices for Right Heart Catheterization in the Diagnosis of Pulmonary Hypertension. Matusov, Yuri, Nicholas A. Kolaitis, Dael Geft, Jacqueline DesJardin, Christopher Barnett, Antoine Hage, Teresa De Marco, and Michael I. Lewis. Chest, May, S0012-3692(25)00579-3.

Immune-Mediated Adverse Events and Overall Survival With Tremelimumab Plus Durvalumab and Durvalumab Monotherapy in Unresectable Hepatocellular Carcinoma: HIMALAYA Phase 3 Randomized Clinical Trial. Lau, George, Bruno Sangro, Ann-Lii Cheng, Masatoshi Kudo, Robin Kate Kelley, Won Young Tak, Antonio Gasbarrini, Maria Reig, Ho Yeong Lim, David Tougeron, Enrico N. De Toni, Vincent C. Tam, Kabir Mody, Jun Gong, Oxana V. Crysler, Wattana Sukeepaisarnjaroen, Oleg Lipatov, Manabu Morimoto, Isabelle Archambeaud, Valentina Burgio, Le Thi Tuyet Phuong, Yee Chao, Jean-Marie Peron, Marie-Luise Berres, Yoo-Joung Ko, Di Ran, Mallory Makowsky, Alejandra Negro, and Ghassan K. Abou-Alfa. Hepatology, May.

Immune-Related Adverse Events Are Associated With Improved Outcomes after Immune Checkpoint Inhibitor Treatment in Hepatocellular Carcinoma: A Systematic Review and Meta-Analysis. Hwang, Soo Young, Mohammad Saeid Rezaee-Zavareh, Abdelrahman M. Attia, Emily A. Kaymen, Nguyen Tran, Ghassan K. Abou-Alfa, Neehar D. Parikh, Amit G. Singal, and Ju Dong Yang. The American Journal of Gastroenterology, May.

Posterior Pituitary Tumors: An Entity Unto Itself. Cooper, Odelia. Pituitary 28 (3): 60.

Foundations and Strategic Vision of the Canadian Translational Geroscience Network. Hajj-Boutros, Guy, Andréa Faust, John Muscedere, Perry Kim, Gilles Gouspillou, Lea Harrington, James L. Kirkland, George A. Kuchel, Jeremy Van Raamsdonk, R. Jane Rylett, Chantal Autexier, Louis R. Lapierre, Michael Kobor, Mohammad Auais, Ann Beliën, Jeroen Aerssens, George Sutphin, Kenneth Rockwood, Alexandra Papaioannou, Marc Sim, Jamie Justice, Nancy Mayo, and Gustavo Duque. The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences, May, glaf111.

Integrated Single-Cell Multiome Analysis Reveals Muscle Fiber-Type Gene Regulatory Circuitry Modulated by Endurance Exercise. Rubenstein, Aliza Batya, Gregory R. Smith, Zidong Zhang, Xi Chen, Toby Leigh Chambers, Frederique Ruf-Zamojski, Natalia Mendelev, Wan Sze Cheng, Michel Zamojski, Mary Anne S. Amper, Venugopalan D. Nair, Andrew Reid Marderstein, Stephen B. Montgomery, Olga G. Troyanskaya, Elena Zaslavsky, Todd Trappe, Scott Trappe, and Stuart C. Sealfon. Genome Research, May, gr.280051.124.

The Kidney Disease Screening and Awareness Program (KDSAP): Transforming Community Outreach and Inspiring Interest in Nephrology. Shah, Kavya M., Jacqueline Lee, Benjamin J. Lee, Ming-Yan Jiang, and Li-Li Hsiao. Clinical Journal of the American Society of Nephrology: CJASN, May.

Neurology

Rapamycin Treatment for Alzheimer’s Disease and Related Dementias: A Pilot Phase 1 Clinical Trial. Gonzales, Mitzi M., Valentina R. Garbarino, Tiffany F. Kautz, Xuemei Song, Marisa Lopez-Cruzan, Leslie Linehan, Candice E. Van Skike, Gabriel A. De Erausquin, Veronica Galvan, Miranda E. Orr, Nicolas Musi, Yingxin He, Randall J. Bateman, Chen-Pin Wang, Sudha Seshadri, Ellen Kraig, and Dean Kellogg. Communications Medicine 5 (1): 189.

Neurosurgery

Conebeam CT Myelography for the Detection of Spinal CSF Leaks. Madhavan, Ajay A., Michelle L. Kodet, Waleed Brinjikji, Ian T. Mark, and Wouter I. Schievink. AJNR. American Journal of Neuroradiology, May.

OBGYN

Improving Inpatient Postpartum Depression Screening: Results From a Quality Improvement Initiative. Woofter, Rebecca, Gwendolyn Hill, Emily Wong, Tiffani J. Bright, Catherine Bresee, Sarah J. Kilpatrick, and Eynav E. Accortt. Archives of Women’s Mental Health, May.

Application of Generative AI to Enhance Obstetrics and Gynecology Research. Kawakita, Tetsuya, Meilssa S. Wong, Kelly S. Gibson, Megha Gupta, Alexis Gimovsky, Hind N. Moussa, and Hye Heo. American Journal of Perinatology, May.

Pathology and Laboratory Medicine

Phospho-RPA2 Predicts Response to Platinum and PARP Inhibitors in Homologous Recombination-Proficient Ovarian Cancer. Schab, Angela, Amanda Compadre, Rebecca Drexler, Megan Loeb, Kevin Rodriguez, Joshua Brill, Shariska Harrington, Carmen Sandoval, Brooke Sanders, Lindsay Kuroki, Carolyn McCourt, Andrea R. Hagemann, Premal Thaker, David Mutch, Matthew Powell, Violeta Serra, Ian S. Hagemann, Ann E. Walts, Beth Y. Karlan, Sandra Orsulic, Katherine Fuh, Lulu Sun, Priyanka Verma, Elena Lomonosova, Peinan Zhao, Dineo Khabele, and Mary M. Mullen. The Journal of Clinical Investigation, May, e189511.

Pediatrics

Current Approaches to the Treatment of Pediatric Soft Tissue Sarcomas: Rhabdomyosarcoma and Nonrhabdomyosarcoma Soft Tissue Sarcomas. Weiss, Aaron R., Andrea Ferrari, Leo Mascarenhas, and Gianni Bisogno. Hematology/Oncology Clinics of North America, May, S0889-8588(25)00042-5.

Partially Differentiated Ileal and Distal-Colonic Human F508del-Cystic Fibrosis-Enteroids Secrete Fluid in Response to Forskolin and Linaclotide. Rong, Yan, Zixin Zhang, Hugo R. de Jonge, Ruxian Lin, Huimin Yu, Rafiq Sarker, Dario Boffelli, Rachel K. Zwick, Ophir D. Klein, Chung-Ming Tse, Mark Donowitz, and Varsha Singh. iScience 28 (5): 112453.

Psychiatry & Behavioral Neurosciences

Regression-Based Normative Data for the Perri Spanish Auditory Verbal Learning and Memory Test in Early-To-Midlife Mexican Adults. Villaseñor-Cabrera, Teresita J, Karen A Sanchez-Jacuinde, Miriam E Jiménez-Maldonado, Alejandra Morlett-Paredes, Enrique López, Genoveva Rizo-Rodriguez, Jose A Navarro-Rincon, Fabiola Gonzalez-Ponce, Mario A Mireles-Ramírez, Miguel Ángel Macías-Islas, Jazmin Marquez-Pedroza, Martha Rocio Hernandez-Preciado, and Edgar R Valdivia-Tangarife. NeuroRehabilitation, May, 10538135251339359.

Radiation Oncology

Patient-Reported Outcomes With Stereotactic Intensity Modulated Radiotherapy After Radical Prostatectomy: A Nonrandomized Clinical Trial. Nikitas, John, Leslie K. Ballas, Tahmineh Romero, Connor Lynch, Ting Martin Ma, Luca F. Valle, Ankush Sachdeva, Natalie Chong, Vince Basehart, Antonio Franco, Robert Reiter, Christopher Saigal, Karim Chamie, Mark S. Litwin, Nicholas M. Donin, Matthew Rettig, Nicholas G. Nickols, Minsong Cao, Stanley L. Liauw, Michael L. Steinberg, and Amar U. Kishan. JAMA Oncology, May, e251059.

Radiate Equity: The Inclusion of Radiation Oncology and Other Specialties in Lymphoma Collaborative Groups. Saifi, Omran, Chelsea C. Pinnix, Chris R. Kelsey, Leslie K. Ballas, Sarah A. Milgrom, Ranjana Advani, Margaret T. Kasner, Stella Flampouri, Stephanie A. Terezakis, Mark Sellmyer, John P. Plastaras, and Bradford S. Hoppe. The Lancet. Haematology, May, S2352-3026(25)00080-8.

Surgery

‘How Are We Going to Harm the next Trauma Patient?’ Trauma Care Providers’ Perspective on Potential Harm to Trauma Patients. Barmparas, Galinos, Bryce Rh Robinson, Babak Sarani, Aaron R. Jensen, Todd W. Costantini, and Avery B. Nathens. Trauma Surgery & Acute Care Open 10 (2): e001628.

Chronic Rejection Models for Vascularized Composite Tissue Allotransplantation. Fisher, Daniel T., Emily Mackey, Eugene Kononov, Paul N. Bogner, Umesh Sharma, Han Yu, Curtis L. Cetrulo, Mukund Seshadri, Pawel Kalinski, Joseph J. Skitzki, Elizabeth A. Repasky, and Minhyung Kim. Scientific Reports 15 (1): 16882.

Contemporary Biology, Management, and Outcomes of Renal Medullary Carcinoma in Children and Adults: A Pediatric Surgical Oncology Research Collaborative Study. Beckhorn, Catherine B., Marcus M. Malek, Harold N. Lovvorn, Harold J. Leraas, Katlyn G. McKay, Nelly-Ange T. Kontchou, Zachary J. Kastenberg, David W. Hoyt, Jonathan P. Roach, Emily K. Myers, Nicholas G. Cost, Bhargava Mullapudi, Elisabeth T. Tracy, et al. Pediatric Blood & Cancer, May, e31774.
 

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