Faculty Publications May 1-8

This week’s edition of Faculty Publications includes Cedars-Sinai studies that were published May 1-8. If you have a published paper from this period that does not appear on this list, please contact Sue Marone.

Cedars-Sinai in the News

Legos Can Be More Than Child’s Play for People With Dementia | AARP
Sarah Kremen, MD 

Cedars-Sinai, Redesign Health Launch End-To-End Digital Health Venture Platform | Fierce Healthcare
Peter Slavin, MD 

Travel As Therapy: Insights From a Psychiatrist | L.A. Parent
Nathalie Murphy, MD 

Help, My Baby Won't let Me Pee Alone! Yep, You've Got a Velcro Baby | Baby Center 
Kyle Monk, MD 

Low-Dose Rifaximin Plus N-Acetylcysteine Superior to Rifaximin Alone in IBS-Diarrhea | Healio Gastroenterology 
Mark Pimentel, MD 

Dr. Karyn S. Eilber Shares Her Reaction to Genitourinary Syndrome of Menopause Guidelines | Urology Times
Karyn Eilber, MD 

Cedars-Sinai Appoints Chief AI Health Research Officer | Becker’s Hospital Review
Sumeet Chugh, MD; Jeffrey Golden, MD 

Stem Cell Innovations Open New Doors in Regenerative Medicine | Nature Portfolio
Eduardo Marbán, MD, PhD; Clive Svendsen, PhD; Arun Sharma, PhD

Faculty Publications

Biomedical Sciences

World of Forms: Deformable Geometric Templates for One-Shot Surface Meshing in Coronary CT Angiography. Herten, Rudolf L. M. van, Ioannis Lagogiannis, Jelmer M. Wolterink, Steffen Bruns, Eva R. Meulendijks, Damini Dey, Joris R. de Groot, José P. Henriques, R. Nils Planken, Simone Saitta, and Ivana Išgum. Medical Image Analysis 103 (April): 103582.

Replacing Body Mass Index With Relative Fat Mass to Accurately Estimate Adiposity. Suthahar, Navin, Richard N. Bergman, and Rudolf A. de Boer. Nature Reviews. Endocrinology, May.

A Hierarchical Model of Early Brain Functional Network Development. Gao, Wei. Trends in Cognitive Sciences, May, S1364-6613(25)00080-4.

Immunopathological and Microbial Signatures of Inflammatory Bowel Disease in Partial RAG Deficiency. Castagnoli, Riccardo, Francesca Pala, Poorani Subramanian, Cihan Oguz, Benjamin Schwarz, Ai Ing Lim, Andrew S. Burns, Elena Fontana, Marita Bosticardo, Cristina Corsino, Angelina Angelova, Ottavia M. Delmonte, Luigi D. Notarangelo, et al. The Journal of Experimental Medicine 222 (8): e20241993.

Cardiac Surgery

Long Term Outcomes of Isolated Tricuspid Surgery in 3,706 Patients: Implications for the Future. Nammalwar, Shruthi, Derrick Y. Tam, Sundos Alabbadi, Allen A. Razavi, Aminah Sallam, Irsa Hasan, Dominic Emerson, Michael E. Bowdish, Natalia Egorova, and Joanna Chikwe. The Journal of Thoracic and Cardiovascular Surgery, April, S0022-5223(25)00271-5.

Cardiology

Insights From the Use of Multipolar Mapping During Ablation of Supraventricular and Ventricular Arrhythmias. Braunstein, Eric D., James K. Gabriels, Ashkan Ehdaie, Jonathan Yarnitsky, Hailei Liu, Archana Ramireddy, Xunzhang Wang, and Michael Shehata. Heart Rhythm O2 6 (4): 402–9.

Long-Term Outcomes of Transcatheter Aortic Valve Replacement of Degenerated Aortic Valve Homograft. Pawar, Shubhadarshini, Vivek Patel, Jair Basantes, Ofir Koren, Tarun Chakravarty, Mamoo Nakamura, Wen Cheng, Sabah Skaf, Hasan Jilaihawi, Raj R. Makkar, and Aakriti Gupta. Journal of the Society for Cardiovascular Angiography & Interventions 4 (4): 102631.

Transfer to Hub Hospitals and Outcomes in Cardiogenic Shock. Pawar, Shubhadarshini, Kannu Bansal, J. Dawn Abbott, Manreet K. Kanwar, Navin K. Kapur, Van-Khue Ton, and Saraschandra Vallabhajosyula. Circulation. Heart Failure 18 (4): e012477.

Challenges in Diagnosing Coronary Microvascular Dysfunction and Coronary Vasospasm. Burgess, Sonya, F. Aaysha Cader, Martha Gulati, Nadia R. Sutton, Yolande Appelman, and Shrilla Banerjee. Cardiovascular Revascularization Medicine: Including Molecular Interventions, April, S1553-8389(25)00176-9.

The Role of GLP-1 Receptor Agonists in Heart Failure: Promise and Unanswered Questions. Farkouh, Michael E., and Jairo T. Nunes. JACC. Heart Failure 13 (5): 767–69.

Incidence and Risk Factors of De Novo Postpartum Hypertension: Understanding Links to Long-Term Cardiovascular Risk. Emeruwa, Ukachi N., Ana Çapi, Marni B. Jacobs, Louise C. Laurent, Natalie A. Bello, and Cynthia Gyamfi-Bannerman. JACC. Advances 4 (6 Pt 1): 101756.

Association of Medical Therapies With Survival According to SPECT MPI Findings. Hijazi, Waseem, Yuanchao Feng, Danielle A. Southern, Derek Chew, Neil Filipchuk, Ilias Mylonas, Mustapha Kazmi, Hamid Banijamali, Bryan Har, Matthew James, Stephen Wilton, Piotr J. Slomka, Daniel Berman, and Robert Jh Miller. Journal of Nuclear Cardiology, May, 102229.

Prognostic Implications and Predictive Factors of Subclinical Leaflet Thrombosis Following Valve-in-Valve Transcatheter Aortic Valve Implantation. Nagasaka, Takashi, Vivek Patel, Kazuki Suruga, Yuchao Guo, Ofir Koren, Alon Shechter, Michelle Friedman, Dhairya Patel, Tarun Chakravarty, Wen Cheng, Aakriti Gupta, Hideki Ishii, Hasan Jilaihawi, Mamoo Nakamura, and Raj R. Makkar. EuroIntervention: Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 21 (9): e482–92.

Thrombus Characterisation and Evolution of Hypoattenuating Leaflet Thickening After Transcatheter Aortic Valve Implantation. Grodecki, Kajetan, Damini Dey, Jolien Geers, Jacek Kwiecinski, Guadalupe Flores Tomasino, Vivek Patel, Caroline Park, Emily Xing, Dhairya Patel, Kazuki Suruga, Aakriti Gupta, Mamoo Nakamura, Mitch Gheorghiu, Tarun Chakravarty, Daniel Berman, Piotr Slomka, Hasan Jilaihawi, and Raj R. Makkar. EuroIntervention: Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 21 (9): e471–81.

Unraveling the Rhythm: Sex-Based Molecular Signatures of Sinus Node Function and Arrhythmia Susceptibility. Ikenouchi, Takashi, Thassio Mesquita, and Eugenio Cingolani. Circulation. Arrhythmia and Electrophysiology, May, e013981.

Phenotypic Clustering Analysis of Patients Rejected for Mitral Valve Interventions: Implications for Future Transcatheter Technologies. Ludwig, Sebastian, Augustin Coisne, Kenza Hamzi, Walid Ben Ali, Andrea Scotti, Benedikt Koell, Alison Duncan, Raj Makkar, Mariama Akodad, Sabine Bleiziffer, Georg Nickenig, Tsuyoshi Kaneko, Hendrik Ruge, Matti Adam, Lars Sondergaard, Gry Dahle, Maurizio Taramasso, Thomas Walther, Joerg Kempfert, Jean-François Obadia, Omar Chehab, Gilbert H. L. Tang, Sachin Goel, Neil Fam, Paolo Denti, Fabien Praz, Ralph Stephan von Bardeleben, Jörg Hausleiter, Azeem Latib, Lenard Conradi, Thomas Modine, Théo Pezel, Juan F. Granada, and CHOICE-MI Investigators. European Heart Journal. Cardiovascular Imaging, May, jeaf141.

Computational Biomedicine

Enhancing Clinical Outcome Predictions Through Effective Sample Size Evaluation in Graph-Based Digital Twin Modeling. Li, Xi, Jui-Hsuan Chang, Mythreye Venkatesan, Zhiping Paul Wang, and Jason H. Moore. BioData Mining 18 (1): 30.

Cost-Effectiveness of Preemptive Plerixafor Versus Rescue Plerixafor for Mobilization and Collection of Hematopoietic Stem Cells in Patients with Multiple Myeloma and Lymphoma. Passos, Roselene Mesquita Augusto, Miriam Allein Zago Marcolino, Júlia Augusto Passos, Vinicius Fernando Calsavara, Leila de Lourdes Martins Perobelli, Alessandro Gonçalves Campolina, and Cesar de Almeida-Neto. Journal of Clinical Apheresis 40 (3): e70026.

Medicine

Outcomes of Isolated Tricuspid Replacement Versus Repair Among Older Patients With Tricuspid Regurgitation in the United States. Shimoda, Tomonari M., Hiroki A. Ueyama, Yoshihisa Miyamoto, Atsuyuki Watanabe, Hiroshi Gotanda, Sammy Elmariah, Yujiro Yokoyama, Shinichi Fukuhara, Tsuyoshi Kaneko, Toshiki Kuno, and Yusuke Tsugawa. JTCVS Open 24 (April): 127–46.

Diagnosis and Management of Gastroesophageal Reflux Disease: A Concise Review for Clinicians. Phillips, Hannah R., Amrit K. Kamboj, and Cadman L. Leggett. Mayo Clinic Proceedings, April, S0025-6196(25)00101-6.

MicroRNA Sequencing of Serum Exosomes Reveals miR205-5p as an Anti-Fibrogenic Factor Against Intestinal Fibrosis in Crohn’s Disease. Xie, Ying, Mieke van Daelen, Rebecca Park, Isabella Almaraz, Lindsey Fontenot, Florian Rieder, Wendy Ho, Berkeley Limketkai, David Q. Shih, Minjie Wei, Yiling Li, and Hon Wai Koon. International Journal of Molecular Sciences 26 (8): 3778.

Immunotherapy in Breast Cancer: Beyond Immune Checkpoint Inhibitors. Choi, Yeonjoo, Jiayi Tan, David Lin, Jin Sun Lee, and Yuan Yuan. International Journal of Molecular Sciences 26 (8): 3920.

Correlation Between Ultrasound-Based Hepatic Steatosis Grade and Thyroid Hormone Levels. Zhang, Xuanxuan, Meijuan Jiang, Wei Zhu, Shouxing Xu, Wenqian Wang, Bin Ying, Xiaoting Chen, Shanshan Zhang, Jianlian Pan, Kai Zhang, Frank Tacke, Ju Dong Yang, and Jian Chen. Gland Surgery 14 (4): 72637–737.

Efficacy of Steroid Pulse to Treat Borderline T-Cell Mediated Rejection on Protocol Kidney Allograft Biopsy. Kirn, Georgia, Sindhu Chandran, Raja Rajalingam, and Sandy Feng. Clinical Transplantation 39 (5): e70171.

Virtual Reality for Menopause Symptom Management: Opportunities, Challenges, and Next Steps. Safwan, Nancy, Karisma K. Suchak, Omer Liran, Sheryl A. Kingsberg, Brennan M. R. Spiegel, Chrisandra L. Shufelt, and Stephanie S. Faubion. Menopause (New York, N.Y.) 32 (5): 475–80.

Muscle Metabolic Resilience and Enhanced Exercise Adaptation by Esr1-Induced Remodeling of Mitochondrial Cristae-Nucleoid Architecture in Males. Zhou, Zhenqi, Timothy M. Moore, Alexander R. Strumwasser, Vicent Ribas, Hirotaka Iwasaki, Noelle Morrow, Alice Ma, Peter H. Tran, Jonathan Wanagat, Thomas Q. de Aguiar Vallim, Bethan Clifford, Zhengyi Zhang, Tamer Sallam, Brian W. Parks, Karen Reue, Orian Shirihai, Rebeca Acin-Perez, Marco Morselli, Matteo Pellegrini, Sushil K. Mahata, Frode Norheim, Mingqi Zhou, Marcus M. Seldin, Aldons J. Lusis, Cathy C. Lee, Mark O. Goodarzi, Jerome I. Rotter, Joshua R. Hansen, Ben Drucker, Tyler J. Sagendorf, Joshua N. Adkins, James A. Sanford, Francesco J. DeMayo, Sylvia C. Hewitt, Kenneth S. Korach, and Andrea L. Hevener. Cell Reports. Medicine, May, 102116.

Tracking Anti-Cytolethal Distending Toxin B and Anti-Vinculin Over Time and Their Roles in Symptoms. Sharabi, Eden, Jonathan A. Busam, Kushagra Mathur, Ali Rezaie, Ruchi Mathur, Ava Hosseini, Mohamad Rashid, and Mark Pimentel. Digestive Diseases and Sciences, May.

Surgical Outcomes of Robotic Bilateral Nephrectomy Compared to Open Surgery in Adult Polycystic Kidney Disease. Castaneda, Peris, John Masterson, Aurash Naser-Tavakolian, Irene Kim, Reiad Najjar, and Amit Gupta. World Journal of Urology 43 (1): 270.

Repair of a Broad, Multisubunit Defect Involving the Mucosal and Cutaneous Lip, Oral Commissure, and Cheek. Sharma, Ajay N., Amanda H. Rosenthal, and Nima M. Gharavi. Dermatologic Surgery, May.

The Growth Hormone-IGF-1 Axis Is a Risk Factor for Long-Term Kidney Allograft Failure. Cusick, Matthew, Viji Nair, Damian Fermin, John Hartman, Jeffrey A. Beamish, Zeguo Sun, Zhongyang Zhang, Edgar Otto, Rajasree Menon, Sudha Nadimidla, Nicholas Demchuk, Kelly Shaffer, Peter Heeger, Weija Zhang, Madhav C. Menon, Matthias Kretzler, Roger C. Wiggins, and Abhijit S. Naik. JCI Insight, May, e188485.

2024 American College of Rheumatology (ACR) Guideline for the Screening, Treatment, and Management of Lupus Nephritis. Sammaritano, Lisa R., Anca Askanase, Bonnie L. Bermas, Maria Dall’Era, Alí Duarte-García, Linda T. Hiraki, Brad H. Rovin, Mary Beth F. Son, Anthony Alvarado, Cynthia Aranow, April Barnado, Anna Broder, Reem A. Mustafa, et al. Arthritis & Rheumatology (Hoboken, N.J.), May.

Consensus and Controversies about Diagnosing GH Deficiency: A Delphi Survey by the GH Research Society. Arlien-Søborg, M. C., S. Radovick, M. C. S. Boguszewski, M. Bidlingmaier, G. Johannsson, A. Grimberg, K. K. Y. Ho, B. M. K. Biller, C. S. Choong, A. R. Hoffman, P. Backeljauw, C. L. Boguszewski, J. Bollerslev, T. Brue, P. Chanson, E. Christ, S. Cianfarani, P. E. Clayton, P. Cohen, A. Dauber, M. Fleseriu, J. Gebauer, A. Giustina, C. E. Higham, R. Horikawa, C. Höybye, A. Juul, M. Lodish, X. Luo, N. Mauras, K. K. Miller, S. Melmed, S. J. C. M. M. Neggers, N. Karavitaki, R. Rosenfeld, R. Ross, L. Savendahl, K. Schilbach, P. F. Collett-Solberg, C. J. Strasburger, N. A. Tritos, H. M. van Santen, K. C. J. Yuen, and J. O. L. Jorgensen. Pituitary 28 (3): 57.

Outcomes of Brexucabtagene Autoleucel in Relapsed/Refractory Acute Lymphoblastic Leukemia Patients With CNS Involvement. Muhsen, Ibrahim N., Gregory W. Roloff, Rawan G. Faramand, Tamer Othman, Yannis K. Valtis, Noam E. Kopmar, Simone E. Dekker, Matthew Connor, Santiago Mercadal, Timothy E. O’Connor, Kaitlyn C. Dykes, Mohamed Ahmed, Nikeshan Jeyakumar, Amy Zhang, Katharine Miller, Katherine C. Sutherland, Caitlin Guzowski, Vishal K. Gupta, Navneet S. Majhail, Minoo Battiwalla, Melhem M. Solh, Shahbaz A. Malik, John Mathews, Caspian Oliai, Paul J. Shaughnessy, Luke Mountjoy, Catherine J. Lee, Aaron C. Logan, Stephanie B. Tsai, Jessica T. Leonard, Marc S. Schwartz, Joshua P. Sasine, Muthu Kumaran, Noelle V. Frey, Jae H. Park, Divya Koura, Ryan D. Cassaday, Bijal D. Shah, Ibrahim Aldoss, Lori S. Muffly, and LaQuisa C. Hill. Blood Advances, May, bloodadvances.2024015779.

Use of Inhaled Treprostinil in Lung Transplant Candidates With Pulmonary Hypertension Associated With Interstitial Lung Disease. Yuen, Alexander D., Lorenzo Zaffiri, Victor Tapson, Reinaldo Rampolla, and Yuri Matusov. Respiratory Care, May.

Orthopaedics

Bioabsorbable PLA/PHA Composite Pins for Orthopedic Applications: In Vitro and in Vivo Study. Sim, Eun Jung, Kumaresan Sakthiabirami, Tae Gon Jung, Seong Kyeong Jo, Su Jung Lee, Pai Xu, Ha Kyoung Sung, Eun Hye Lee, Ki Chull Yoon, Kwan Su Kang, Yong Hoon Jeong, David B. Thordarson, Choong Sik Lee, Sung Min Kim, Chan Kang, Jae Hwang Song, and Won Ho Park. Journal of Industrial and Engineering Chemistry 146 (June): 861–70.

Pathology and Laboratory Medicine

Perspective on the Use of Fluorescence Molecular Imaging for Peripheral and Deep En Face Margin Assessment. Nguyen, Hang M., Veronica C. Torres, Joshua Levy, Eunice Y. Chen, Matthew LeBoeuf, and Kimberley S. Samkoe. Journal of Biomedical Optics 30 (Suppl 1): S13711.

A Descriptive 5-Year Analysis of the Demographics and Therapies for Patients With Immune Thrombotic Thrombocytopenic Purpura in the USA: A Multicenter Study of 390 Disease Episodes From 2017 to 2021. Jacobs, Jeremy W., Brian D. Adkins, Garrett S. Booth, Caroline G. Stanek, Elizabeth S. Allen, Brenda J. Grossman, Laura D. Stephens, Elizabeth P. Crowe, Laetitia Daou, Marisa B. Marques, Rance C. Siniard, Lisa R. Wallace, Chisa Yamada, Miriam Andrea Duque, Yanyun Wu, Omar Aljuboori, Thomas J. Harrington, Diana M. Byrnes, Quentin Eichbaum, Cristina A. Figueroa Villalba, Justin E. Juskewitch, Ellen Klapper, Ingrid Perez-Alvarez, Monica S. Klein, Fatima Aldarweesh, Rahaf Alkhateb, Meredith G. Parsons, Annette J. Schlueter, Christopher A. Tormey, Allison P. Wheeler, Amy A. Powers, Christopher B. Webb, Sean G. Yates, Evan M. Bloch, and Jay S. Raval. Journal of Clinical Apheresis 40 (2): e70017.

Pediatrics

Compound Heterozygous MRPS14 Variants Associated With Leigh Syndrome. Otero, Maria Gabriela, Christina Freeman, Ruchi Shah, Renkui Bai, Hong Cui, Marian Castro, Zachary Myers, Eric Choy, Derek Chan, Molly Easter, Sophia Y. Zhao, Madeline Babros, Ruchi Garg, Matthew Deardorff, Franklin Moser, and Tyler Mark Pierson. Annals of Clinical and Translational Neurology, May.

Radiation Oncology

A Resident’s Guide to Evaluation of Prostate High Dose Rate Brachytherapy Treatment Plans: An American Brachytherapy Society Technical Report. Sherwani, Zohaib, Ulysses Gardner, Irina Vergalasova, Hong Zhang, Daniel Song, Surendra Prajapati, Pretesh Patel, Mitchell Kamrava, and Lara Hathout. Practical Radiation Oncology, April, S1879-8500(25)00116-X.

Surgery

A New Method for Preparation of Decellularized Human Scaffolds for Facial Reconstruction. Lupon, Elise, Aylin Acun, Alec R. Andrews, Ruben Oganesyan, Hyshem H. Lancia, Laurent Lantieri, Mark A. Randolph, Curtis L. Cetrulo, Alexandre G. Lellouch, and Basak E. Uygun. Current Issues in Molecular Biology 47 (4): 275.

Single-Stage Latissimus-Implant Breast Reconstruction Is Safe and Reliable: A Single Surgeon Series of 207 Flaps. Aref, Youssef, Yasmina Samaha, Hamzah Almadani, Brianne Mitchell, Edward C. Ray, Randolph Sherman, and Philip S. Brazio. Annals of Plastic Surgery 94 (5S Suppl 3): S457–64.

The Landmark Series: Surgical Management of Functioning and Non-Functioning Pancreatic Neuroendocrine Tumors. Tobias, Joseph, Callisia N. Clarke, Alexandra Gangi, and Xavier M. Keutgen. Annals of Surgical Oncology, May.

Epigenetic Mechanisms in Melanoma Development and Progression. Joo, Hyunjeong, Ximena Diaz Olea, Aojia Zhuang, Bin Zheng, Hyungsoo Kim, and Ze’ev A. Ronai. Trends in Cancer, May, S2405-8033(25)00099-8.

Artificial Intelligence Performs Well for Patient-Level Education of Benign Anorectal Conditions. Marty, Makenna, Seija Maniskas, Jonathan Zuo, Gabriel Akopian, and Adam Truong. The American Surgeon, May, 31348251337156.

Urology

Overtreatment of Prostate Cancer in Men With Limited Life Expectancy-A Global Phenomenon? Daskivich, Timothy J., and John T. Leppert. JAMA Network Open 8 (5): e258576.

Overtreatment in Prostate Cancer: An Overused Term-Reply. Daskivich, Timothy J., and John T. Leppert. JAMA Internal Medicine, May.

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