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March
2025
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Faculty Publications March 13-20

A Comprehensive Digest of Research Publications From Cedars-Sinai Investigators and a Sampling of Recent Media Coverage Featuring Faculty

This week’s edition of Faculty Publications includes Cedars-Sinai studies that were published March 13-20. If you have a published paper from this period that does not appear on this list, please contact Sue Marone.

 

Cedars-Sinai in the News

Front-Line Healthcare Workers Reflect on Early Days of COVID 5 Years After WHO Declared Pandemic | ABC News
Kimberly Shriner, MD 

Single-neuron Recordings Are Helping To Unravel Complexities of Human Cognition | The Transmitter
Ueli Rutishauser, PhD 

Is Alzheimer’s Hereditary? Expert Breaks Down the Risks | Prevention
Zaldy Tan, MD, MPH 

North Texas Mother Hopes 14-Year Journey With Rare Heart Disease Inspires Others | Fox4 News
Tyler Gunn, MD 

These Subtle Differences Between Coughs Can Reveal a lot About Your Illness | HuffPost
Jiyeon Seo, MD

Mixed Results for Therapeutic Candidates for Platinum-Resistant Ovarian Cancer | MedPageToday
BJ Rimel, MD

 Is There a Best Diet for Atrial Fibrillation? | Health Central
Christine Albert, MD, MPH 

AI-Enhanced Echocardiography: A Game-Changer for Opportunistic Liver Disease Detection? | Medscape 
Alan C. Kwan, MD

 

Faculty Publications

Anesthesiology

Pain During Cesarean Delivery: Tools for Doing Better. Zakowski, M., M. A. Lee, and M. Hofkamp. International Journal of Obstetric Anesthesia 62 (January): 104328.

Effect of IV Acetaminophen Administration in the Perioperative Period on the Quality of Postoperative Pain Relief and Adverse Side Effects. Elvir-Lazo, Ofelia Loani, Alicia L. Romero-Navarro, Pravjit Bhatti, Sana Zubair, Roya Yumul, and Paul F. White. Journal of Surgery and Research 8 (1): 145–57.

Biomedical Sciences

LGB (Lesbian, Gay, and Bisexual) State Policy Protections and Substance Use Disparities. Guan, Alice, Paul Wesson, David V. Glidden, Rita Hamad, Judy Y. Tan, and Scarlett L. Gomez. Health Affairs Scholar 3 (3): qxaf029.

AI-Driven Report-Generation Tools in Mental Healthcare: A Review of Commercial Tools. Bouguettaya, Ayoub, Victoria Team, Elizabeth M. Stuart, and Elias Aboujaoude. General Hospital Psychiatry 94 (March): 150–58.

Comprehensive Proteomics Metadata and Integrative Web Portals Facilitate Sharing and Integration of LINCS Multiomics Data. Vidović, Dušica, Behrouz Shamsaei, Stephan C. Schürer, Phillip Kogan, Szymon Chojnacki, Michal Kouril, Mario Medvedovic, Wen Niu, Evren U. Azeloglu, Marc R. Birtwistle, Yibang Chen, Tong Chen, Michael J. MacCoss, et al. Molecular & Cellular Proteomics: MCP, March, 100947.

Differential Impact of Recent Heavy Drinking on First and Recurrent Acute Pancreatitis. Jeon, Christie Y., Yu Ye, Georgios I. Papachristou, James L. Buxbaum, Joseph R. Pisegna, Cheryl J. Cherpitel, Esther A. Adeniran, Minoti Apte, Eleanor Chang, Anil K. Dasyam, Gayathri D. Jalluri, Charlotte A. Lansky, Aurelia Lugea, Zarine K. Shah, Richard T. Waldron, Stephen J. Pandol, and Dhiraj Yadav. Alcohol, Clinical & Experimental Research, March.

Improving Fat Saturation Robustness in Outer Extremity MRI With a Local Shim Coil Insert. Long, Ziyang, Hsin-Jung Yang, Nader Binesh, Archana Vadiraj Malagi, Yun Shang, Li-Ting Huang, Jeremy Zepeda, Fardad Michael Serry, Debiao Li, and Hui Han. Magnetic Resonance in Medicine, March.

Cardiac Surgery

Mortality and Stroke After Routine Left Atrial Appendage Occlusion in Patients Undergoing Isolated Mitral Repair Without Atrial Fibrillation in the United States. Tam, Derrick Y., Aminah Sallam, Qiudong Chen, George Gill, Armin Kiankhooy, Stephen E. Fremes, Mario Gaudino, Richard Whitlock, Michael E. Bowdish, and Joanna Chikwe. The Journal of Thoracic and Cardiovascular Surgery, March, S0022-5223(25)00204-1.

Cardiology

Prescription of Pregabalin for Prevention of Acute Post-Mastectomy Pain Syndrome (APMPS): A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Ganduboina, Rohit, Palak Dutta, Shubhadarshini G. Pawar, and Indraneil Mukherjee. Annals of Medicine and Surgery (2012) 87 (2): 830–37.

Are ORBITA Trials Practice-Changing? Zores, Florian, and Sanjay Kaul. Progress in Cardiovascular Diseases, March, S0033-0620(25)00034-9.

Clinical Standards in Angina and Non-Obstructive Coronary Arteries: A Clinician and Patient Consensus Document. Berry, Colin, Paolo G. Camici, Filippo Crea, Maria George, Juan Carlos Kaski, Peter Ong, Carl J. Pepine, Annette Pompa, Udo Sechtem, Hiroaki Shimokawa, Christopher Zeitz, Javier Escaned, Tim P. van de Hoef, John F. Beltrame, C. Noel Bairey Merz, and Coronary Vasomotor Disorders International Study (COVADIS) Group. International Journal of Cardiology, March, 133162.

Advances in Our Understanding of Cardiovascular Diseases After Preeclampsia. Countouris, Malamo E., and Natalie A. Bello. Circulation Research 136 (6): 583–93.

Antiarrhythmic Effects of Mirabegron on Ventricular Fibrillation in Langendorff-Perfused Rabbit Ventricles. Liu, Xiao, Yen-Ling Sung, Liyang Zhang, Shuai Guo, Minjing Yang, James E. Tisdale, Zhenhui Chen, Joshua I. Goldhaber, Michael Rubart, Xiaochun Li, and Peng-Sheng Chen. The Journal of Physiology, March.

GenomicGapID: Leveraging Spatial Distribution of Conserved Genomic Sites for Broad-Spectrum Microbial Identification. Asthana, Vishwaratn, Pallavi Bugga, Clara Elaine Smith, Catherine Wellman, Zachary Dwight, Piyush Ranjan, Erika Martínez Nieves, Robert P. Dickson, and J. Scott VanEpps. Microbiology Spectrum, March, e0281724.

Lifelong Care of Females With Congenital Heart Disease. Tompkins, Rose, Prashanth Venkatesh, Adam J. Small, and Dan G. Halpern. Circulation Research 136 (6): 553–65.

Cardiac Auscultation Skills Among Medical Trainees. Zhang, Neil S., Joy Y. Yang, Joshua I. Goldhaber, Binh An P. Phan, and Melvin D. Cheitlin. American Heart Journal, March, S0002-8703(25)00085-7.

Myocardial Proteome in Human Heart Failure With Preserved Ejection Fraction. Jani, Vivek P., Edwin J. Yoo, Aleksandra Binek, Alina Guo, Julie S. Kim, Jennifer Aguilan, Mohammad Keykhaei, Sydney R. Jenkin, Simone Sidoli, Kavita Sharma, Jennifer E. Van Eyk, David A. Kass, and Virginia S. Hahn. Journal of the American Heart Association 14 (6): e038945.

Myocardial Biomarkers in Coronary Microvascular Dysfunction: Response to Ranolazine. Hampilos, Katherine E., Anum Asif, Puja K. Mehta, Daniel S. Berman, Galen Cook-Wiens, Michael D. Nelson, Carl J. Pepine, C. Noel Bairey Merz, and Janet Wei. American Heart Journal Plus: Cardiology Research and Practice 52 (April): 100513.

Computational Biomedicine

An Open Letter to Graduate Students and Other Procrastinators: It’s Time to Write. Hazelett, Dennis J. Nature Biotechnology 43 (3): 447–50.

Medicine

A Phase IIa Clinical Trial to Evaluate the Effects of Anti-Retroviral Therapy in Alzheimer’s Disease (ART-AD). Sullivan, A. Campbell, Gabrielle Zuniga, Paulino Ramirez, Roman Fernandez, Chen-Pin Wang, Ji Li, Lisa Davila, Kristine Pelton, Sandra Gomez, Claira Sohn, Elias Gonzalez, Marisa Lopez-Cruzan, David A. Gonzalez, Alicia Parker, Eduardo Zilli, Gabriel A. de Erausquin, Sudha Seshadri, Sara Espinoza, Nicolas Musi, and Bess Frost. NPJ Dementia 1 (1): 2.

Multi-Centered Clinical Validation Demonstrating Superior Precision in Lupus Diagnosis: T Cell Autoantibodies and TC4d Outperform Conventional Lupus Erythematosus Biomarkers. Kyttaris, Vasileios, Daniel J. Wallace, Arezou Khosroshahi, Andrew Concoff, Nicole Wilson, Chau Ching Liu, Susan Manzi, Joseph Ahearn, Sepehr Taghavi, Touba Warsi, Stanley Park, Christine Schleif, Brittany D. Partain, and Tyler O’Malley. Frontiers in Immunology 16: 1518208.

The Association Between Nutrient Patterns and Hospital Stay Duration and Symptoms in COVID-19 in Iranian Patients: Cross-Sectional Study. Mirzababaei, Atieh, Farideh Shiraseb, Azam Mohamadi, Mahya Mehri Hajmir, Sara Ebrahimi, Zeinab Zarrinvafa, Elham Kazemian, Amir Mehrvar, and Khadijeh Mirzaei. Frontiers in Nutrition 12: 1542449.

Clinical Outcomes and Molecular Characteristics of Lung-Only and Liver-Only Metastatic Pancreatic Cancer: Results From a Real-World Evidence Database. Levi, Abrahm, Edik Blais, John Davelaar, Matthew I Ebia, Angela Minasyan, Nima Nikravesh, Gillian Gresham, Lei Zheng, Jennifer W Chuy, Rachna T Shroff, Raymond Couric Wadlow, Patricia DeArbeloa, Lynn McCormick Matrisian, Emmanuel Petricoin, Michael J Pishvaian, Jun Gong, Andrew Eugene Hendifar, and Arsen Osipov. The Oncologist 30 (3): oyaf007.

Associations of Sociodemographic, Clinical Factors and HLA-B Alleles With Enthesitis and Peripheral Arthritis in Patients With Ankylosing Spondylitis. Naovarat, Benjamin Sornrung, Lianne Gensler, Michael Ward, Mark Hwang, Amirali Tahanan, Mohammad Hossein Rahbar, Mariko Ishimori, MinJae Lee, Matthew A. Brown, Michael H. Weisman, and John D. Reveille. RMD Open 11 (1): e004589.

CD105 Blockade Restores Osimertinib Sensitivity in Drug-Resistant EGFR-Mutant Non-Small Cell Lung Cancer. Thiruvalluvan, Manish, Sandrine Billet, Zhenqiu Liu, Joseph Lownik, Barliz Waissengrin, Hyoyoung Kim, Anton L. Villamejor, Larry Milshteyn, Xiamo Li, Matthew Gayhart, Manuel Araña, Kamya Sankar, Edwin M. Posadas, Jean Lopategui, Sungyong You, Karen L. Reckamp, and Neil A. Bhowmick. Drug Resistance Updates: Reviews and Commentaries in Antimicrobial and Anticancer Chemotherapy 81 (March): 101237.

Holistic AI Analysis of Hybrid Cardiac Perfusion Images for Mortality Prediction. Marcinkiewicz, Anna M., Wenhao Zhang, Aakash Shanbhag, Robert J. H. Miller, Mark Lemley, Giselle Ramirez, Mikolaj Buchwald, Aditya Killekar, Paul B. Kavanagh, Attila Feher, Edward J. Miller, Andrew J. Einstein, Terrence D. Ruddy, Joanna X. Liang, Valerie Builoff, David Ouyang, Daniel S. Berman, Damini Dey, and Piotr J. Slomka. NPJ Digital Medicine 8 (1): 158.

Heterogeneous Effects of Genetic Variants and Traits Associated With Fasting Insulin on Cardiometabolic Outcomes. Sevilla-González, Magdalena, Kirk Smith, Ningyuan Wang, Aubrey E. Jensen, Elizabeth M. Litkowski, Hyunkyung Kim, Daniel A. DiCorpo, Sarah Hsu, Jinrui Cui, Ching-Ti Liu, Chenglong Yu, John J. McNeil, Paul Lacaze, Kenneth E. Westerman, Kyong-Mi Chang, Philip S. Tsao, Lawrence S. Phillips, Mark O. Goodarzi, Rob Sladek, Jerome I. Rotter, Josée Dupuis, Jose C. Florez, Jordi Merino, James B. Meigs, Jin J. Zhou, Sridharan Raghavan, Miriam S. Udler, and Alisa K. Manning. Nature Communications 16 (1): 2569.

Receiving Immunotherapy for the Treatment of Advanced Renal Cell Carcinoma Is Associated With Higher Burden of Illness, Coagulopathy, Cardiac Arrhythmia, and Disparities. Eichhorn, Susan, Roberto Pili, Joel B. Epstein, Richa Rajesh, and Poolakkad S. Satheeshkumar. Supportive Care in Cancer, 33 (4): 285.

Endocrine-Exocrine miR-503-322 Drives Aging-Associated Pancreatitis via Targeting MKNK1 in Acinar Cells. Liu, Kerong, Tingting Lv, Lu He, Wei Tang, Yan Zhang, Xiao Xiao, Yating Li, Xiaoai Chang, Shusen Wang, Stephen J. Pandol, Ling Li, Xiao Han, and Yunxia Zhu. Nature Communications 16 (1): 2613.

Frailty Incidence by Diabetes Treatment Regimens in Older Adults With Diabetes Mellitus in the ASPirin in Reducing Events in the Elderly Study. Espinoza, Sara E., Jonathan C. Broder, Rory Wolfe, Michael E. Ernst, Raj C. Shah, Suzanne G. Orchard, Robyn L. Woods, Joanne Ryan, and Anne Murray. GeroScience, March.

Global Burden and Cross-Country Inequalities in Urinary Tumors From 1990 to 2021 and Predicted Incidence Changes to 2046. Feng, De-Chao, Deng-Xiong Li, Rui-Cheng Wu, Jie Wang, Yu-Han Xiao, Koo Han Yoo, Xing Ye, Wu-Ran Wei, De-Pei Kong, and Zhou-Ting Tuo. Military Medical Research 12 (1): 12.

Reducing Catheter-Associated Urinary Tract Infection Rates in Surgical Critical Care Units via an Informal Catheter Exchange Protocol. Shen, Aricia, Ryan Raypon, Meghan Madhusudhan, Michael Nurok, Tejal Brahmbhatt, Jonathan D. Grein, Galinos Barmparas, and Michael A. Ben-Aderet. Infection Control and Hospital Epidemiology, March, 1–3.

Safety and Efficacy of Long-Term Treatment of Type 1 Plasminogen Deficient Patients With Intravenous Plasminogen Replacement Therapy. Shapiro, Amy D., Heather McDaniel, Robert W. Decker, Charles Nakar, Jeremy Lorber, Neelam Thukral, Joseph M. Parker, and Karen Thibaudeau. Haemophilia: March.

Advance Care Planning Before and After In-Hospital Cardiac Arrest. Polyak, Alexander, Phillip Ryan Tacon, Zachary Krom, Oren Friedman, James Mirocha, and Yuri Matusov. The American Journal of Hospice & Palliative Care, March, 10499091251328019.

Immune Checkpoint Inhibitor Therapy for Aggressive Pituitary Neuroendocrine Tumors. Lin, Andrew L., Vasilisa Rudneva, Adam Newton, Nazanin K. Majd, Rajiv Magge, Soma Sengupta, Bernard Goichot, Anna Piotrowski, Igor Gavrilovic, Odelia Cooper, Marc Rosenblum, Thomas Kaley, Ingo Mellinghoff, Robert J. Young, Mark T. A. Donoghue, Viviane Tabar, and Eliza B. Geer. The Journal of Clinical Endocrinology and Metabolism, March, dgaf178.

Neurology

Paraneoplastic Leucine Zipper 4 IgG Associated Motor-Predominant Polyradiculoneuropathy. Panrudkevich, Alex, Duaa Jabari, Brendan Putko, Catherine Daley, Richard A. Lewis, Divyanshu Dubey, and Marcus V. Pinto. Journal of the Peripheral Nervous System: JPNS 30 (1): e70013.

Neurosurgery

Quality Improvement in Neurosurgery: A Systematic Review. Madan, Mohamed M., Ahmed M. Alshereiqi, Noor M. Abdulla, Maryam Albreiki, and Tariq Al-Saadi. Medicine International 5 (3): 23.

Blood-Brain Barrier Crossing Biopolymer Activates Immunity in Primary Brain Lymphoma by Targeting c-Myc and α-PD-1: Artificial Intelligence Analysis. Ljubimov, Vladimir A., Tao Sun, Jiawei Wang, Lian Li, Paul Z. Wang, Alexander V. Ljubimov, Eggehard Holler, Keith L. Black, Jindřich Kopeček, Julia Y. Ljubimova, and Jiyuan Yang. Journal of Controlled Release, March, 113611.

Long-Term Reoperation Rates After Single-Level Lumbar Discectomy: A Nationwide Cohort Study. Etigunta, Suhas K., Andy M. Liu, Adeesya Gausper, Vivien Chan, Justin Scheer, Tiffany Perry, David L. Skaggs, Corey Walker, and Alexander Tuchman. Spine, March.

Cost of Pediatric Traumatic Brain Injury in Developing Countries: A Retrospective Cohort Study. Al Fudhaili, Aisha Nasser, Sara Salim Al Mashrafi, Ahad Nasser Al Ghammari, Aisha Khalifa Al Saadi, Fatema Taheri Boriawala, and Tariq Al-Saadi. Child’s Nervous System: ChNS: 41 (1): 134.

Author Response to Letter to the Editor Regarding ‘Comparison of Rostral Facet Joint Violations in Robotic- and Navigation-Assisted Pedicle Screw Placement for Adult Lumbar Spine Instrumentation.’ Perry, Tiffany G., Paal K. Nilssen, Alexander Tuchman, and David L. Skaggs. The Spine Journal: 25 (4): 854–56.

OBGYN

Potential Glycobiomarkers in Maternal Obesity and Gestational Diabetes During Human Pregnancy. Farkas, Anna, Andrea Suranyi, Balint Kolcsar, Zita Gyurkovits, Zoltan Kozinszky, Sandor G. Vari, and Andras Guttman. Journal of Clinical Medicine 14 (5): 1626.

Trends and Outcomes of Minimally Invasive Hysterectomy Among Older Women. Meyer, Raanan, Ogechukwu Ezike, Katharine Ciesielski, Nhat Ngo, Shainlee Taing, Walter Gotlieb, and Gabriel Levin. Maturitas 196 (March): 108244.

Content, Quality, and Reliability of Endometriosis Videos on YouTube. McGough, Alexandra, Rebecca J. Schneyer, Kacey M. Hamilton, Gabriel Levin, Matthew T. Siedhoff, Kelly N. Wright, and Raanan Meyer. Journal of Obstetrics and Gynaecology Canada: JOGC = Journal d’obstetrique et Gynecologie Du Canada: JOGC, March, 102814.

Fertility Preservation in People With Cancer: ASCO Guideline Update. Su, H. Irene, Christina Lacchetti, Joseph Letourneau, Ann H. Partridge, Rubina Qamar, Gwendolyn P. Quinn, Joyce Reinecke, James F. Smith, Megan Tesch, W. Hamish Wallace, Erica T. Wang, and Alison W. Loren. Journal of Clinical Oncology, March, JCO2402782.

Orthopaedics

Facet Joint Loading after 1-, 2- and 3-Level Cervical Disc Arthroplasty: A Comparison of Spiked Versus Keeled Baseplates. Cuellar, Jason M., Todd Lanman, Nicole Mottole, Michael Wernke, Elizabeth Carruthers, and Antonio Valdevit. North American Spine Society Journal 19 (September): 100512.

Long-Term Bladder, Bowel, and Ambulatory Function After Sacrectomy Surgery. Coan, Joshua M., Jordan O. Gasho, Joseph J. Connolly, Santiago A. Lozano-Calderon, Kevin A. Raskin, Joseph H. Schwab, and Daniel G. Tobert. Spine, March.

Angiotensin-Converting Enzyme Inhibition as a Potential Risk Factor for Periprosthetic Joint Infection Following Total Knee Arthroplasty. Trikha, Rishi, Nicolas Cevallos, Alan L. Zhang, Sanjiv M. Narayan, Christos Photopoulos, Alexandra Stavrakis, and Nicholas M. Bernthal. Arthroplasty Today 32 (April): 101641.

Association of Knee Osteoarthritis Treatment Types, Patient Characteristics, and Medical History With Subsequent Risk for Total Knee Arthroplasty: Data From a New Real-World Registry. Concoff, Andrew L., Jennifer H. Lin, Andrew I. Spitzer, Vinod Dasa, Adam Rivadeneyra, David Rogenmoser, Mitchell K. Ng, Mary DiGiorgi, Stan Dysart, Joshua Urban, William M. Mihalko, and Michael A. Mont. Arthroplasty Today 32 (April): 101643.

Improved Sleep Associated With Triamcinolone Acetonide Extended-Release Injections for Knee Osteoarthritis: Use of a New Real-World Registry. Mont, Michael A., Jennifer H. Lin, Andrew I. Spitzer, Vinod Dasa, Adam Rivadeneyra, David Rogenmoser, Andrew L. Concoff, Mitchell K. Ng, Mary DiGiorgi, Stan DySart, Joshua Urban, and William M. Mihalko. Arthroplasty Today 32 (April): 101655.

Pathology and Laboratory Medicine

Carbamylated Albumin, Heart Failure, and Mortality in Patients Undergoing Coronary Angiography. Yazdani, Babak, Graciela E. Delgado, Anders H. Berg, Christoph Wanner, Bernhard K. Krämer, Winfried März, Marcus E. Kleber, and Christiane Drechsler. Clinical Chemistry, March, hvaf021.

Radiation Oncology

FDG PET/CT Images Demonstrating Subclinical Pancreatitis in a Patient on a GLP-1 Receptor Agonist. Lenkov, Robert, Tyler Berman, Inderjit Mehmi, and Pareen Mehta. Clinical Nuclear Medicine, March.

Surgery

CT Pan-Scanning Versus Targeted Imaging Among Older Adults After Ground Level Falls. Touponse, Gavin, Jeff Choi, Christian Calderon, Sofia E. Luna, Lakshika Tennakoon, and Ara Ko. Trauma Surgery & Acute Care Open 10 (1): e001534.

A Guide to the Implementation and Design of Ex Vivo Perfusion Machines for Vascularized Composite Allotransplantation. Berkane, Yanis, Haizam Oubari, Nicolas Bertheuil, and Alexandre G. Lellouch. Plastic and Reconstructive Surgery. Global Open 13 (3): e6624.

Advancements in Face Lift Techniques: Preservation Face Lift With a Rotating Pedicle Flap. Sadati, Kevin, Olivier Mathieu, Curtis L. Cetrulo, and Alexandre G. Lellouch. Plastic and Reconstructive Surgery. Global Open 13 (3): e6619.

Simultaneous Vascularized Lymph Node Transfer and Breast Reconstruction: A Systematic Review. Almadani, Hamzah, Jocelyn Lu, Sara Bokhari, Christiane How-Volkman, and Philip S. Brazio. Journal of Clinical Medicine 14 (5): 1694.

Trials and Tribulations of a Urinary Incontinence Screening Tool. Kanji, Falisha F., Tara Cohen, Claire S. Burton, Catherine Bresee, Joshua Pevnick, Teryl Nuckols, Neil Wenger, and Jennifer T. Anger. Urogynecology (Philadelphia, Pa.), March.

Long Non-Coding RNA AC133552.2: Biomarker and Therapeutic Target in Osteosarcoma via PANoptosis Gene Screening. Zhao, Wenrui, Yameng Wang, Junchao Zhu, Shahrzad Arya, Guowen Huang, Shengqin Li, Qi Chen, Xijuan Liu, Jinghong Yuan, and Jingyu Jia. Scientific Reports 15 (1): 9180.