Faculty Publications June 5-12
A Comprehensive Digest of Research Publications From Cedars-Sinai Investigators and a Sampling of Recent Media Coverage Featuring Faculty
This week’s edition of Faculty Publications includes Cedars-Sinai studies that were published June 5-12. If you have a published paper from this period that does not appear on this list, please contact Sue Marone.
Cedars-Sinai in the News
Valence Sams Receives a Triple Organ Transplant At Cedars-Sinai | NBC Nightly News
Nicholas Nissen, MD
Avoid This 1 Type of Salt to Protect Your Heart Health, Cardiologist Says | Today
Susan Cheng, MD
AI, the Disruptor in Chief | Politico
Elias Aboujaoude, MD
The Next-Gen Sweetener You May Be Eating—And Inhaling | WebMD
Ruchi Mathur, MD
SWOG S2302 Pragmatica-Lung Study Design Still Significant Even With Negative Results In Advanced NSCLC | The ASCO Post
Karen Reckamp, MD
El Verano: Un Nuevo Reto Para los Niños Afectados Por los Incendios Forestales En Los Ángeles | Enlace Judío
Eugene Kim, MD
The Promise of Precise Medicine: Targeted Radiotherapy Pluvicto Shows More Progress in Treating Advanced Prostate Cancer | SurvivorNet
Stephen Freedland, MD
Why Pulsed Field Ablation for Afib Is the New Go-To Treatment | HealthCentral
Michael Shehata, MD
Faculty Publications
Anesthesiology
Leaflet Modification During Transcatheter Aortic Valve-in-Valve Replacement - Imaging Guidance for the ShortCutTM Procedure. Ternacle, Julien, Marian Kukucka, Benjamin Seguy, Sabah Skaf, Moody Makar, Shemy Carasso, Daniel Kalbacher, Thomas Modine, Susheel Kodali, Didier Tchetche, Danny Dvir, and Philippe Pibarot. Journal of the American Society of Echocardiography, June, S0894-7317(25)00290-1.
Biomedical Sciences
Tumoricidal Efficacy of Artesunate-Eluting Microsphere: Differential Role of Bax/Bak in Orchestration of Cell Death Pathways. Helmueller, Sarah, Sanghee Lee, Xinxin Song, Dong-Hyun Kim, and Yong J. Lee. Biomaterials Research 29: 0217.
Sex Differences in Brain-Behavior Relationships in the First 2 Years of Life. Fenske, Sonja J., Janelle Liu, Haitao Chen, Marcio A. Diniz, Rebecca L. Stephens, Emil Cornea, John H. Gilmore, and Wei Gao. Cerebral Cortex (New York, N.Y.: 1991) 35 (6): bhaf133.
Targeting the Interaction Between Long Noncoding RNA XR_001779380 and Prdm1 to Enhance IFN-γ Immunity in Murine Neonatal Intestinal Epithelial Cells. Jin, Kehua, Ai-Yu Gong, Shuhong Wang, Gislaine A. Martins, Juliane K. Strauss-Soukup, Roberta M. O’Connor, and Xian-Ming Chen. mBio, June, e0077325.
Caspase-1-Dependent Pyroptosis Converts αSMA+ CAFs Into Collagen-IIIhigh iCAFs to Fuel Chemoresistant Cancer Stem Cells. Gao, Hongbo, Stephen Q. R. Wong, Ethan Subel, Yung Hsing Huang, Yu-Cheng Lee, Kazukuni Hayashi, Mark Ellie Alonzo, Mustafa Karabicici, Xen Ping Hoi, Armine Kasabyan, Qianxing Mo, Zachary Melchiode, Ziad El-Zaatari, Steven Shen, Raj Satkunasivam, Fotis Nikolo, and Keith Syson Chan. Science Advances 11 (24): eadt8697.
Cardiology
Summary of the International Society for Heart and Lung Transplantation Consensus Conference on Emerging Understanding of Antibodies and Antibody-Mediated Rejection in Heart Transplantation. Kobashigawa, Jon, Andreas Zuckermann, Adriana Zeevi, Markus J. Barten, Patricia P. Chang, Monica Colvin, Guillaume Coutance, Anne Dipchand, Stephan Ensminger, Marta Farrero, Marlena Habal, Anne Halpin, Annette M. Jackson, Yosef Manla, Kavitha Muthiah, Luciano Potena, Elaine F. Reed, Kelly Schlendorf, Palak Shah, Anat Tambur, Simon Urschel, Steven Webber, Lori West, Jong-Chan Youn, Jignesh Patel, and Consensus Conference participants. The Journal of Heart and Lung Transplantation, April, S1053-2498(25)01775-9.
Role of Bariatric Surgery in Patients With Advanced Heart Failure. Kim, Darae, In-Cheol Kim, Jong-Chan Youn, Jin-Jin Kim, Mi-Hyang Jung, Jin-Oh Choi, Daniel Seong Kyu Kim, Mason Lee, Evan P. Kransdorf, David H. Chang, Michelle M. Kittleson, Michele Hamilton, Jignesh K. Patel, Fardad Esmailian, and Jon A. Kobashigawa. Surgery for Obesity and Related Diseases, May, S1550-7289(25)00717-8.
South Asians and Cardiometabolic Health: A Framework for Comprehensive Care for the Individual, Community, and Population - An American Society for Preventive Cardiology Clinical Practice Statement. Rohatgi, Anand, Sonia S. Anand, Meghana Gadgil, Unjali P. Gujral, Sneha S. Jain, Zulqarnain Javed, Manish Jha, Parag H. Joshi, Venkat Sanjay Manubolu, Khurram Nasir, Pradeep Natarajan, Neha Pagidipati, Latha Palaniappan, Aniruddh P. Patel, Priyanka Satish, Nilay S. Shah, Garima Sharma, Madhukar H. Trivedi, Salim S. Virani, Martha Gulati, and Jaideep Patel. American Journal of Preventive Cardiology 22 (June): 101000.
Prognostic Value of Plaque Burden Assessed by Coronary CT Angiography in Known Coronary Artery Disease. Cho, Sung Woo, Tina Torbati, Su Nam Lee, Heidi Gransar, Damini Dey, Piotr Slomka, Sean W. Hayes, John D. Friedman, Louise E. J. Thomson, Alan Rozanski, Rebekah Park, Daniel S. Berman, and Donghee Han. Journal of Cardiovascular Computed Tomography, June, S1934-5925(25)00343-0.
3-Year Outcomes of Mitral Valve-in-Valve Therapy Using Balloon-Expandable Transcatheter Valves in the United States. Eleid, Mackram F., Amar Krishnaswamy, Samir Kapadia, Pradeep Yadav, Vivek Rajagopal, Raj Makkar, Curtiss Stinis, Stanley Chetcuti, Andrew Morse, Tiberio Frisoli, Antonio H. Frangieh, Amr E. Abbas, Brian Whisenant, William W. O’Neill, Mayra E. Guerrero, Evelio Rodriguez, Susheel Kodali, Gorav Ailawadi, and Charanjit S. Rihal. JACC. Cardiovascular Interventions 18 (11): 1454–66.
Optimization of Renin-Angiotensin-Aldosterone Inhibitor Therapies for Evidence-Based Indications: A Call to Action From the Cardio-Kidney Community. Pecoits-Filho, Roberto, Michelle M. Y. Wong, Monica Moorthy, Debasish Banerjee, Suman Behera, Viviane Calice-Silva, Mogamat-Yazied Chothia, Gates B. Colbert, Martha Gulati, Charles A. Herzog, Fadi Jouhra, Edgar V. Lerma, Charu Malik, Kershaw V. Patel, Amina Rakisheva, Giuseppe M. C. Rosano, Priyanka Satish, Henry H. L. Wu, and Angela Yee-Moon Wang. ESC Heart Failure, June.
Reply: Donor Selection for Heart Transplantation and Regulatory Ghosts? Debunking the Myth of ‘No Oversight’ in European Heart Transplantation. Jain, Rashmi, Evan P. Kransdorf, and Jon A. Kobashigawa. JACC. Heart Failure 13 (8): 102509.
Aging and Sinus Node Dysfunction: Mechanisms and Future Directions. Mesquita, Thassio, Rodrigo Miguel-Dos-Santos, and Eugenio Cingolani. Clinical Science (London, England: 1979) 139 (11): CS20231025.
The 4 Longest Days. Kittleson, Michelle M. Journal of the American College of Cardiology 85 (23): 2337–38.
Parasympathetic Response in Women With Coronary Vascular Dysfunction During Mental Stress Compared to Those With Non-Cardiac Chest Pain and Reference Controls. Mehta, Puja K., Shafa-At A. Sheikh, Esha K. Dave, Rahim K. Shakoor, Tina Torbati, Amit Shah, Marc D. Thames, Liu Qiang, Yi-An Ko, Janet Wei, Chrisandra Shufelt, Michael D. Nelson, Bruce Samuels, Babak Azarbal, Jeanie Park, Michael R. Irwin, David S. Krantz, and C. Noel Bairey Merz. International Journal of Cardiology. Heart & Vasculature 59 (August): 101673.
Computational Biomedicine
Leveraging Social Determinants of Health in Alzheimer’s Research Using LLM-Augmented Literature Mining and Knowledge Graphs. Shang, Tianqi, Shu Yang, Weiqing He, Tianhua Zhai, Dawei Li, Bojian Hou, Tianlong Chen, Jason H. Moore, Marylyn D. Ritchie, and Li Shen. AMIA Joint Summits on Translational Science Proceedings. AMIA Joint Summits on Translational Science 2025: 491–500.
Ovarian Cancer Risk and Survival According to Tumor Sex Hormone Receptor Expression: An Ovarian Cancer Association Consortium and Ovarian Tumor Tissue Analysis Consortium Pooled Analysis. Fu, Zhuxuan, Lauren Borho, Sarah E. Taylor, Linda E. Kelemen, Anna DeFazio, Penelope M. Webb, Martin Köbel, Nicola S. Meagher, Renhua Na, Antonis C. Antoniou, Alison H. Brand, Catherine J. Kennedy, Francesmary Modugno, et al. Gynecologic Oncology 198 (June): 112–29.
Medicine
Caregiver Burden in Lung Transplantation: A Review. Sankar, Keerthana, Anne Johnson, Kathryn McRae, Reinaldo Rampolla, and Nicholas A. Kolaitis. JHLT Open 8 (May): 100239.
The Safety of Pharmacotherapy for Irritable Bowel Syndrome: A Systematic Review and Meta-Analysis. Busam, Jonathan A., Nisha Batta, Eric D. Shah, LiJin Joo, Caroline Marshall, Ali Rezaie, and Mark Pimentel. The American Journal of Gastroenterology, June.
Multiparametric Magnetic Resonance Imaging May Improve Detection of Patients With At-Risk MASH: Real World Experience in Hepatology Clinics. Phipps, Meaghan M., Tatiana Hage, Emily Truong, Ju Dong Yang, Lauren Nicolosi, Andrea Dennis, Elizabeth Shumbayawonda, Prashant Pandya, and Julia Wattacheril. Digestive and Liver Disease, June, S1590-8658(25)00794-7.
Pretransplant Natural Antibody Levels Identify a Subset of Deceased Donor Kidney Transplant Recipients That Benefit From Infliximab Induction. Petr, Vojtech, Filip Tichanek, Samuel L. Liu, Felix Poppelaars, Brandon Renner, Jennifer Laskowski, Shrey Purohit, Ming Zhao, Diana Jalal, Peter S. Heeger, and Joshua M. Thurman. American Journal of Transplantation, June, S1600-6135(25)00295-3.
82Rb PET Myocardial Blood Flow Quantification: Influence of Arterial Input Curve Quality on Diagnostic Accuracy. Fujito, Hidesato, Mark Lemley, Valerie Builoff, Wenhao Zhang, Keiichiro Kuronuma, Giselle Ramirez, Aditya Killekar, Joanna X. Liang, Paul Kavanagh, Mark C. Hyun, Sean W. Hayes, Louise E. J. Thomson, John D. Friedman, Serge D. Van Kriekinge, Marcelo F. Di Carli, Damini Dey, Daniel S. Berman, and Piotr J. Slomka. Journal of Nuclear Cardiology, June, 102270.
Priming With Specific Context Improves Large Language Model Performance on Nuclear Cardiology Board Preparation Test. Hijazi, Waseem, Valerie Builoff, Aditya Killekar, Aakash Shanbhag, Robert Jh Miller, Damini Dey, Joanna X. Liang, Kathleen Flood, Daniel Berman, Jamieson M. Bourque, Lawrence M. Phillips, Panithaya Chareonthaitawee, and Piotr J. Slomka. Journal of Nuclear, June, 102269.
Uncovering PD-L1 Among Immune Cell Predictive Biomarkers and Actionable Genetic Alterations in Anal Squamous-Cell Carcinomas in the Era of Immunotherapy. Sharma, G., Y. Baca, A. F. Shields, A. Prakash, B. A. Weinberg, A. Saeed, S. Goel, A. Abdalla, M. Oberley, J. Xiu, J. Hwang, E. S. Antonarakis, V. K. Chiu, and E. Lou. ESMO Open 10 (6): 105315.
Unlocking the Therapeutic Potential of Protocatechualdehyde: Pharmacological Applications and Mechanism Insights. Mssillou, Ibrahim, Youness El Abdali, Fatima Ez-Zahra Amrati, Adrian Lim, Asaad Khalid, Hafiz A. Makeen, Mohammed Albratty, Youssra Lefrioui, Boutaina Louafi, and Dalila Bousta. Naunyn-Schmiedeberg’s Archives of Pharmacology, June.
Neurology
Working Together in Sarcoidosis: Experience and Impact of a Formalized Multidisciplinary Discussion. Sharp, Michelle, Ali M. Mustafa, Kristen Mathias, Jasmine Malhi, Edward S. Chen, Stephen C. Mathai, Barney J. Stern, Susana C. Dominguez-Penuela, Paula Barreras, and Nisha A. Gilotra. Annals of the American Thoracic Society, June.
Neurosurgery
Commentary: Surgical Treatment of Spontaneous Intracranial Hypotension From Spinal CSF Leak: Single Institution Case Series. Garcia, Catherine M., Wouter I. Schievink, and Julie L. Chan. Neurosurgery, June.
Feature-Based Encoding of Face Identity by Single Neurons in the Human Amygdala and Hippocampus. Cao, Runnan, Jinge Wang, Chujun Lin, Emanuela De Falco, Alina Peter, Hernan G. Rey, Peter Brunner, Jon T. Willie, James J. DiCarlo, Alexander Todorov, Ueli Rutishauser, Xin Li, Nicholas J. Brandmeir, and Shuo Wang. Nature Human Behaviour, June.
Rate of Conversion to Fusion Following Cervical Laminectomy Versus Laminoplasty: A Retrospective Analysis of 4,406 Patients. Liu, Andy M., Adeesya Gausper, Suhas K. Etigunta, Alexander Tuchman, Christopher Mikhail, David Skaggs, and Vivien Chan. Global Spine Journal, June, 21925682251347502.
Socioeconomic Status as a Determinant of Survival in Glioblastoma: A Systematic Review and Meta-Analysis. Wijaya, Jeremiah Hilkiah, Saad Hulou, Brandon Lucke-Wold, Wiley Braxton Gillam V, Chris B. Lamprecht, Fnu Ruchika, Bryce Schneider, Devon Foster, Pouria Abolfazli, Miguel David Quintero-Consuegra, Zahraa F. Al-Sharshahi, and Julius July. Neurosurgical Review 48 (1): 500.
Nursing
Guest Editorial. Batcheller, Joyce, and David Marshall. Nursing Administration Quarterly 49 (3): 153–54.
Pathology and Laboratory Medicine
Boosting Angiotensin-Converting Enzyme (ACE) in Microglia Protects Against Alzheimer’s Disease in 5xFAD Mice. Gomez, Andrew R., Hyae Ran Byun, Shaogen Wu, A. K. M. Ghulam Muhammad, Jasmine Ikbariyeh, Jaelin Chen, Alek Muro, Lin Li, Kenneth E. Bernstein, Richard Ainsworth, and Warren G. Tourtellotte. Nature Aging, June.
Blood Pressure and Late Pregnancy Circulating miRNAs in the MADRES Study. Anderson, Elizabeth C., Meghan E. Muse, Zhongzheng Niu, Helen B. Foley, Joshua J. Levy, Megan E. Romano, Jiang Gui, Jessica L. Bentz, Shohreh F. Farzan, Theresa M. Bastain, Carmen J. Marsit, Carrie V. Breton, and Caitlin G. Howe. Journal of the American Heart Association, June, e040416.
Dapagliflozin in Addition to Ramipril Ameliorates Kidney Disease Progression in Mice With Alport Syndrome. Miyata, Kana N., Denise M. Smith, Michifumi Yamashita, Shimok Kim, F. Andrea Yeargin, Melisa Beganovic, Shao-Ling Zhang, John S. D. Chan, Jeffrey H. Miner, Daniel N. Leal, Jian-Ping Li, and Jonathan Bruno. American Journal of Physiology. Renal Physiology, June.
Radiation Oncology
Gender-Based Differences in X Usage Among Orthopedic Surgeons at Top-Ranked US Hospitals: Cross-Sectional Analysis. Gasho, Jordan O., Daniel G. Tobert, and Katelyn M. Atkins. Journal of Medical Internet Research 27 (June): e69366.
Roadmap: Medical Physics Technologies in Brachytherapy. Song, William Youngjae, Michael Roumeliotis, Junghoon Lee, Aaron Fenster, Jessica Rodgers, Tiana Trumpour, Rachel Glicksman, Alejandro Berlin, Åsa Carlsson Tedgren, Javier Vijande, Luc Beaulieu, Björn Morén, Sandra Michelle Meyers, Alexandra Rink, Yin Gao, Benjamin Fahimian, Debarghya China, Kai Ding, Tarun Podder, Eric Carver, Mark J. Rivard, Susan Richardson, Milan Grkovski, Moeen Meftahi, Ulysses Gardner, Rachit Kumar, Daniel Scanderbeg, Catheryn Yashar, Issam El Naqa, Akila N. Viswanathan, and Xun Jia. Physics in Medicine and Biology, June.
Urothelial Carcinoma: Perioperative Considerations From Top to Bottom. Yip, Wesley, Salvador Jaime-Casas, Anjaney Kothari, Mary Sullivan, Leslie K. Ballas, Domenique Escobar, Anne K. Schuckman, Jonathan E. Rosenberg, and Jonathan A. Coleman. CA: A Cancer Journal for Clinicians, June.
Surgery
A Systematic Review Supporting the Development of the Society for Vascular Surgery Clinical Practice Guidelines on the Management of Blunt Thoracic Aortic Injury. Firwana, Mohammed, Mohamed Seisa, Magdoleen Farah, Reem Alsibai, April Christensen, Yahya Alsawaf, Alzhraa Abbas, Bashar Hasan, Samer Saadi, Larry J. Prokop, Ali Azizzadeh, and M. Hassan Murad. Journal of Vascular Surgery, June, S0741-5214(25)01289-3.
Patient and Clinician Perspectives on Misgendering in Healthcare. Okamuro, Kyle, Alan Card, Hanna J. Barton, Falisha Kanji, Victor Trasvina, Jill Blumenthal, Tara Cohen, and Jennifer T. Anger. BMJ Quality & Safety, June, bmjqs-2024-018364.
Economic Impact of In-Office Pediatric Tympanostomy Tube Placement Using a Tympanostomy Tube Delivery Device in a Commercially- and Medicaid-Insured US Population. Moynihan, Meghan, Ryan Ross, Joseph Delgado, Mark Gerber, and Gene Liu. Journal of Medical Economics 28 (1): 899–909.
Urology
Extracellular Vesicle Heterogeneity Through the Lens of Multiomics. Silva, Taylon F., Elizabeth Hutchins, Wenyan Zhao, Yari Ciani, Minhyung Kim, Emily Ko, Javier Mariscal, Zhuyu Qiu, Fatima Bedier, Agnes Kittel, Bo Zhou, Yang Wang, Megan Hall, Francesca Galasso, Rebecca Reiman, Michael R. Freeman, Sarah Parker, Jennifer Van Eyk, Wei Yang, Edwin Posadas, Jlenia Guarnerio, John Nolan, Clotilde Théry, Andries Zijlstra, Shannon Stott, Sungyong You, Francesca Demichelis, Paul C. Boutros, Kendall Van Keuren-Jensen, and Dolores Di Vizio. Cell Reports. Medicine, June, 102161.
Sustained Macrophage Reprogramming Is Required for CD8+ T Cell-Dependent Long-Term Tumor Eradication. Jardim, Carolina, Marta Bica, Mariana Reis-Sobreiro, Afonso Teixeira da Mota, Raquel Lopes, Miguel Ferreira Pinto, Neuza Sousa, Sofia Mensurado, Henning Boekhoff, Tommaso Scolaro, Maud Reugebrink, Natacha Goncalves-Sousa, Hiroshi Kubo, Catarina Monteiro Gomes, Catarina Brito, Rafael Argüello, Elvira P. Leites, Vanessa A. Morais, Bruno Silva-Santos, Nuno L. Barbosa-Morais, and Karine Serre. Cancer Immunology Research, June.
Genes Driving Three-Dimensional Growth of Immortalized Cells and Cancer. Basu, Mukta, Jin-Fen Xiao, Saravana Kumar Kailasam Mani, Fangyuan Qu, Yongqi Lin, Jason Duex, Huihui Ye, Vanessa Neang, and Dan Theodorescu. Cell Death & Disease 16 (1): 442.
ONECUT2 Reprograms Neuroendocrine Fate and Is an Actionable Therapeutic Target in Small Cell Lung Cancer. Gutiérrez, Mirian, Irene Zamora, Raquel Iriarte, María José Pajares, Qian Yang, Chen Qian, Nerea Otegui, Joaquín Fernández-Irigoyen, Enrique Santamaría, Nicolas Alcala, Alexandra Sexton-Oates, Lynnette Fernández-Cuesta, Miguel Barajas, Alfonso Calvo, Luis M. Montuenga, Beatrice Knudsen, Sungyong You, Michael R. Freeman, Ignacio Encío, and Mirja Rotinen. Molecular Medicine (Cambridge, Mass.) 31 (1): 232.
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