Faculty Publications June 26-July 3
A Comprehensive Digest of Research Publications From Cedars-Sinai Investigators and a Sampling of Recent Media Coverage Featuring Faculty
This week’s edition of Faculty Publications includes Cedars-Sinai studies that were published June 26-July 3. If you have a published paper from this period that does not appear on this list, please contact Sue Marone.
Cedars-Sinai in the News
LA First Responders Face Growing Concerns in Months After Wildfires | ABC News
Susan Cheng, MD
Thinking About Taking a Stab at IV Therapy? Ask Some Questions First | Associated Press
Sam Torbati, MD
A Year After Being Cured of Diabetes, Patient Graduates | KTLA
Todd Brennan, MD
IBS Rates Nearly Doubled During the Pandemic | HealthDay
Christopher Almario, MD; Brennan Spiegel, MD
Is Your Coffee Habit the Ultimate Longevity Secret? New Research Says It Might Be | Women's Health
Bert Mandelbaum, MD
As Mosquito Season Peaks, Officials Brace for New Normal of Dengue Cases | California Healthline
Michael Ben-Aderet, MD
How to Find the Right Ulcerative Colitis Doctor for You: 7 Steps | Everyday Health
Gil Melmed, MD
Controlling Blood Pressure Lowers Dementia Risk, A New Study Finds | HealthCentral
Joseph Ebinger, MD
Faculty Publications
Biomedical Sciences
Impaired Splicing Machinery in Craniopharyngiomas Unveils PRPF8 and RAVER1 as Novel Biomarkers and Therapeutic Targets. Fuentes-Fayos, Antonio C., Miguel E. G-García, Teresa Sánchez-Medianero, John Apps, Álvaro Flores-Martínez, Ana S. De la Rosa-Herencia, Ignacio Gil-Duque, Georg Otto, Eva Venegas-Moreno, Eugenio Cárdenas Ruiz-Valdepeñas, Aura D. Herrera-Martínez, Juan Solivera, Manuel D. Gahete, David A. Cano, Rosa Ortega, Alfonso Soto-Moreno, María A. Gálvez-Moreno, Juan Pedro Martínez-Barberá, and Raúl M. Luque. Acta Neuropathologica Communications 13 (1): 142.
Diagnostic Performance of Liver FibraChek Dx©, a Blood-Based Test for the Non-Invasive Detection of Liver Cirrhosis and Cancer. Siguencia, Fernando, Michitaka Matsuda, Vijay Pandyarajan, Sunao Tanaka, Steven M. Smith, Catherine Bresee, Ekihiro Seki, Charles J. Rosser, and Hideki Furuya. World Journal of Hepatology 17 (6): 106481.
Spatial Transcriptomic Analysis of Immune Checkpoint Blockade Response in Triple Negative Breast Cancers With Tertiary Lymphoid Structures. Mebane, Richard H., Teia Noel, Nathan Ing, Kenneth H. Gouin, Aagam Shah, David Zitser, Andrew Martinez, Gaorav Gupta, Sandra Demaria, Lorenzo Galluzzi, Alice Ho, Heather McArthur, Stephen L. Shiao, and Simon R. V. Knott. iScience 28 (7): 112808.
Cardiac Surgery
Supine Blood Pressure and Cardiovascular Risk-Reply. Giao, Duc M., and Stephen P. Juraschek. JAMA Cardiology, July.
Cardiology
Heart Transplant and Durable Mechanical Circulatory Support for Specific Less-Common Cardiomyopathies. Roussoulières, Ana, Marta Farrero, Finn Gustafsson, Michelle Kittleson, Mrudula Munagala, and Josef Stehlik. CJC Open 7 (6): 813–20.
Lifestyle Interventions in Cardiovascular-Kidney-Metabolic Syndrome JACC: Advances Expert Panel. Shahid, Izza, Jerrin Philip, Eleonora Avenatti, Deepika Laddu, Michael D. Shapiro, Amit Khera, Ambarish Pandey, Chiadi E. Ndumele, Martha Gulati, Khurram Nasir, and Kershaw V. Patel. JACC. Advances 4 (6 Pt 2): 101788.
Impact of Estrogen Replacement on Endothelial Dysfunction and Psychological Health in Women With Hypothalamic Amenorrhea. Shufelt, Chrisandra L., Nancy Safwan, Mariam Saadedine, Galen Cook-Wiens, Jenna Maughan, Margareta D. Pisarska, JoAnn E. Manson, Sarah L. Berga, Stephanie S. Faubion, Prediman K. Shah, and C. Noel Bairey Merz. The Journal of Clinical Endocrinology and Metabolism, June, dgaf364.
Time-to-Event Analysis of the Long-Term Outcome in Trials Comparing Transcatheter and Surgical Aortic Valve Implantation: A Meta-Analysis. Barili, Fabio, Francesco Pollari, Mateo Marin-Cuartas, Amedeo Anselmi, Manuela de la Cuesta, James M. Brophy, William E. Boden, Raffaele De Caterina, Victor Dayan, Jorge R. Roda, Miguel Sousa Uva, Rui M. S. Almeida, Jacques Tomasi, Jean-Philippe Verhoye, Francesco Musumeci, John Mandrola, Sanjay Kaul, Stefania Papatheodorou, Alessandro Parolari, and Integritty. International Journal of Cardiology, June, 133524.
Remote Hemodynamic Monitoring for Heart Failure: In or On? Kransdorf, Evan P., and Hal A. Skopicki. JACC. Heart Failure 13 (8): 102507.
Refractory Angina: Mechanisms and Stratified Treatment in Obstructive and Non-Obstructive Chronic Myocardial Ischaemic Syndromes. Silva, Ranil de, Kevin Cheng, Timothy D. Henry, Divaka Perera, Viviany R. Taqueti, Ana Abreu, Fabienne Vervaat, Martha Gulati, Hiroaki Shimokawa, Felicita Andreotti, and Juan-Carlos Kaski. European Heart Journal, July, ehaf284.
Computational Biomedicine
Vibe Coding: A New Paradigm for Biomedical Software Development. Moore, Jason H., and Nicholas Tatonetti. BioData Mining 18 (1): 46.
Emergency Medicine
When Is It Acceptable to Terminate Resuscitation in Prehospital Settings? Libby, Christopher, and Scott H. Pasichow. AMA Journal of Ethics 27 (7): E484-490.
Medicine
Activity of Brigatinib in Patients With Crizotinib-Resistant ALK-Positive Non-Small-Cell Lung Cancer According to ALK Fusion and Mutation Status. Bazhenova, Lyudmila, J. G. Hodgson, D. Ross Camidge, Corey J. Langer, Rudolf M. Huber, Dong-Wan Kim, Karen L. Reckamp, Myung-Ju Ahn, Daniel S. W. Tan, Jyoti D. Patel, Sylvie Vincent, Cong Li, Michael J. Humphries, Pingkuan Zhang, Victor M. Rivera, and Scott Gettinger. Clinical Lung Cancer, June, S1525-7304(25)00128-7.
Hydrogen Sulfide and Methane on Breath Test Correlate With Human Small Intestinal Hydrogen Sulfide Producers and Methanogens. Villanueva-Millan, Maria Jesus, Gabriela Leite, Ruchi Mathur, Ali Rezaie, Cristina Moreno Fajardo, Juliana de Freitas Germano, Walter Morales, Maritza Sanchez, Ignacio Rivera, Gonzalo Parodi, Stacy Weitsman, Mohamad Rashid, Ava Hosseini, Daniel Brimberry, Gillian M. Barlow, and Mark Pimentel. Digestive Diseases and Sciences, June.
Relationship of Intestinal Ultrasound With Clinical, Biochemical, And Endoscopic Disease Severity in Acute Severe Ulcerative Colitis: A Blinded, Prospective Study. Gu, Phillip, David Ziring, Puja V. Khanna, Waseem Ahmed, Eric Vasiliauskas, Andres Yarur, Stephan Targan, Dermot Pb McGovern, Shervin Rabizadeh, Phillip Fleshner, Maria T. Abreu, and Gil Y. Melmed. Clinical and Translational Gastroenterology, June.
Secondary Peristalsis Is More Affected Than Primary Peristalsis by Increased Intragastric Pressure After Metabolic Bariatric Surgery: Findings From Functional Lumen Imaging Probe and High-Resolution Esophageal Manometry. Ravi, Karthik, Varan Perananthan, Mark Hanscom, Farah Abdul Razzak, Rudy Mrad, Donna Maria Abboud, Karim Al Annan, Anthony Kerbage, Blake Kassmeyer, Andrew Storm, Eric J. Vargas Valls, Omar M. Ghanem, and Barham K. Abu Dayyeh. Neurogastroenterology and Motility, June, e70110.
The Translational Research Program in Cancer Differences Across Populations. Figueiredo, Jane C., Diana Redwood, Li Li, Elizabeth Donato, Daniel Fort, Eric E. Fox, William M. Grady, Heather Green, Tabitha A. Harrison, Carl Haupt, Li Hsu, Meredith A. J. Hullar, Jeroen R. Huyghe, Wenora Johnson, Amanda L. Koehne, Scott D. LaBrie, Meredith A. Lakey, MingGang Lin, Nicole C. Loroña, Grace A. Maresh, Marc Matrana, Jonathan D. Mizrahi, Sarah H. Nash, Nathalie T. Nguyen, Jennifer L. Paruch, Amanda I. Phipps, Conghui Qu, Timothy W. Randolph, Stephanie Romo, Claire E. Thomas, Sushma Thomas, James Tiesinga, Charles Whitlow, Cecilia C. S. Yeung, Hang Yin, Craig M. Zibilich, Christopher I. Li, Timothy K. Thomas, and Ulrike Peters. Cancer Epidemiology, Biomarkers & Prevention: A Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology, June.
Appropriate Use and Complications of Corticosteroids in Inflammatory Bowel Disease: A Comprehensive Review. Feuerstein, Joseph D., David T. Rubin, Faten N. Aberra, Andreas Yarur, and Lisa Malter. Clinical Gastroenterology and Hepatology, June, S1542-3565(25)00535-X.
The Use of Virtual Reality During Arterial Puncture and Evaluating Its Impact on Patient-Reported Pain Scores, Anxiety Scores, and Patient Satisfaction. Upadhyaya, Pradeep, James Mirocha, Kimberly Fuleihan, and Benga Agbelemose. Respiratory Care, June.
Longitudinal Patient Outcomes Over 18 Months Following a Hip, Clinical Vertebral, Distal Forearm, or Proximal Humerus Fracture in the United States: Results From the ICUROS US Study. Silverman, Stuart, Deborah Gold, Michael Nichol, John Schousboe, Rebecca Smith, Anna Tosteson, and ICUROS Study Group. JBMR Plus 9 (7): ziaf077.
A Phase 1 Safety and Feasibility Trial of a Ketogenic Diet Plus Standard of Care for Patients with Recently Diagnosed Glioblastoma. Amaral, L. J., Gillian Gresham, Sungjin Kim, Mourad Tighiouart, Thomas A. Nelson, Amelia Welborn, Laura Lockshon, Brandon Noorvash, Jeremy D. Rudnick, Scott A. Irwin, Stephen J. Freedland, and Jethro Hu. Scientific Reports 15 (1): 21064.
Reply: Interpreting Real-World Data in Advanced HCC- Need for Clarity on Subsequent Therapies, Adverse Events, and Follow-up Adequacy. Ahn, Joseph C., Wee Han Ng, Yee Hui Yeo, Amit G. Singal, and Ju Dong Yang. Hepatology (Baltimore, Md.), July.
Neurology
Feasibility of Cognitive Testing and Ecological Momentary Assessments Using Smartphones in Middle Aged and Older Adults with Insomnia. Ghadimi, Sara, Jason Ereso, Alexander J. Kaula, Nick Taptiklis, Francesca Cormack, Cathy Alessi, Jennifer L. Martin, Joseph M. Dzierzewski, Arash Naeim, Sarah Kremen, Tue Te, and Constance H. Fung. BMC Digital Health 3 (1): 21.
Distinct Subnetworks of the Mouse Anterior Thalamic Nuclei. Hintiryan, Houri, Mitchell Rudd, Sumit Nanda, Adriana E. Gutierrez, Darrick Lo, Tyler Boesen, Luis Garcia, Jiandong Sun, Christian Estrada, Hyun-Seung Mun, Seita Yamashita, Yeji E. Han, Ian Bowman, Lin Gou, Chunru Cao, Jennifer Gonzalez, Keivan Moradi, Qiuying Zhao, Inga Yenokian, Aishwarya Dev, Brian Zingg, Hanpeng Xu, Qing Xue, Muye Zhu, Lijuan Liu, Xin Chen, Zhixi Yun, Hanchuan Peng, Nicholas N. Foster, and Hong-Wei Dong. Nature Communications 16 (1): 6018.
Neurosurgery
The First Grade III Lumbar Spondylolisthesis Treated With the Novel 360° Artificial Disc/Artificial Facet Replacement Solution. Ament, Jared D., Jack Petros, Cooper Gardner, and Amir Vokshoor. International Journal of Spine Surgery, June, 8769.
Return-to-Sport Recommendations for Athletes With Cervical Spine Trauma: A Modified Delphi Consensus Survey of Expert Opinion. Zuckerman, Scott L., Jacob Jo, Grant H. Rigney, Julian E. Bailes, Christopher M. Bonfield, Robert C. Cantu, Patrick C. H. Chan, Andrew M. Cordover, Domagoj Coric, Hank Feuer, Raymond J. Gardocki, Andrew C. Hecht, Wellington K. Hsu, Jacob R. Joseph, Ronald A. Lehman, Allan D. Levi, Susan M. Liew, Philip K. Louie, Steven C. Ludwig, Joseph Maroon, Vincent J. Miele, Jeff Mullin, Venu M. Nemani, Frank M. Phillips, Sheeraz Qureshi, K. Daniel Riew, Myron A. Rogers, Rick C. Sasso, Gabriel A. Smith, Jay D. Turner, Alexander R. Vaccaro, Robert G. Watkins, Nicholas Theodore, David O. Okonkwo, Allen K. Sills, and Gavin A. Davis. Neurosurgery, June.
Return-to-Sport Recommendations for Athletes With Congenital Cervical Spine Pathology: A Modified Delphi Consensus Survey of Expert Opinion. Zuckerman, Scott L., Jacob Jo, Grant H. Rigney, Julian E. Bailes, Christopher M. Bonfield, Robert C. Cantu, Patrick C. H. Chan, Andrew M. Cordover, Domagoj Coric, Hank Feuer, Raymond J. Gardocki, Andrew C. Hecht, Wellington K. Hsu, Jacob R. Joseph, Ronald A. Lehman, Allan D. Levi, Susan M. Liew, Philip K. Louie, Steven C. Ludwig, Joseph Maroon, Vincent J. Miele, Jeff Mullin, Venu M. Nemani, Frank M. Phillips, Sheeraz Qureshi, K. Daniel Riew, Myron A. Rogers, Rick C. Sasso, Gabriel A. Smith, Jay D. Turner, Alexander R. Vaccaro, Robert G. Watkins, Nicholas Theodore, David O. Okonkwo, Allen K. Sills, and Gavin A. Davis. Neurosurgery, June.
Surgical Approaches for Pediatric Colloid Cysts: Insights From a Systematic Review of Techniques, Outcomes, and Global Practice Patterns. ElSharaawy, Ahmed, Younis Al-Mufargi, Ahmed Al-Wahaibi, Alaa Alsharawy, Adhalia Al-Shuaili, and Tariq Al-Saadi. Child’s Nervous System: ChNS, 41 (1): 222.
OBGYN
Leveraging Chorionic Villus Biopsies for the Derivation of Patient-Specific Trophoblast Stem Cells. Varberg, Kaela M., Ayelen Moreno-Irusta, Allynson Novoa, Brynne Musser, Joseph M. Varberg, Jeremy P. Goering, Irfan Saadi, Khursheed Iqbal, Hiroaki Okae, Takahiro Arima, John Williams, Margareta D. Pisarska, and Michael J. Soares. Communications Biology 8 (1): 964.
Orthopaedics
Is ‘Patch and Run’ the New Way to Address Partial Rotator Cuff Tears? Agarwalla, Avinesh, and Joseph N. Liu. Arthroscopy: The Journal of Arthroscopic & Related Surgery, June, S0749-8063(25)00445-1.
Advances in Endoscopic Lumbar Spine Surgery: A Comprehensive Review of the Techniques Used for the Treatment of Lumbar Disc Herniations and Spinal Stenosis and Lumbar Spinal Fusion. Kwon, Brian, and Andrew Moon. The Spine Journal, June, S1529-9430(25)00302-X.
A Prospective, Randomized Comparison of Functional Bracing and Spica Casting for Femoral Fractures Showed Equivalent Early Outcomes. Andras, Lindsay M., Julia S. Sanders, Tiffany N. Phan, Sarah R. Purtell, Jasmine Gasca, Tishya A. L. Wren, Andrew T. Sim, David Skaggs, Andrea Kramer, Michelle Chavez, and Robert Kay. The Journal of Bone and Joint Surgery. American Volume, June.
Trajectory of Recovery Following Total Ankle Arthroplasty Using Patient-Reported Outcomes Measurement Information System (PROMIS). Piscoya, Andres, Callie Liu, Stephanie Chen, Zachary Rockov, Brett Ewing, Max Michalski, David Thordarson, and Timothy Charlton. Foot & Ankle International, June, 10711007251343526.
Navigation Is Associated With Lower Risk of Neurological Injury and Transfusion in Pediatric Idiopathic Scoliosis Surgery. Chan, Vivien, Suhas Etigunta, Adeesya Gausper, Andy M. Liu, Kenneth D. Illingworth, Grant D. Hogue, Daniel J. Hedequist, and David L. Skaggs. Spine Deformity, June.
Pathology and Laboratory Medicine
ESBL-Producing Escherichia Coli and Klebsiella Pneumoniae Exhibit Divergent Paths During In-Human Evolution Towards Carbapenem Resistance. Kalu, Michelle Chioma, Akanksha Acharya, Peter Jorth, and Annie Wong-Beringer. Microorganisms 13 (6): 1387.
Clinicopathologic Findings in Native Liver Biopsies After Heart Transplantation and Total Artificial Heart Implantation. Kozak, Michael, Mahzad Azimpouran, Xiaomo Li, Danielle A. Hutchings, Keith Lai, Kevin M. Waters, Maha Guindi, and Brent K. Larson. Human Pathology 161 (June): 105861.
Pediatrics
Syndrome of the Month: Bosma Arhinia Microphthalmia Syndrome. Patterson, Katherine J. K., John M. Graham, and Natalie D. Shaw. American Journal of Medical Genetics. Part A, July, e64127.
Growth Arrest Specific-6 and Angiotoxin Receptor-like Signaling Drive Oral Regenerative Wound Repair. Griffin, Michelle F., Jessica Cook, Annah Morgan, Dario Boffelli, Mauricio Downer, Amanda F. Spielman, Nicholas J. Guardino, Jason L. Guo, Jennifer B. L. Parker, Michael Januszyk, Caleb Valencia, Maxwell Kuhnert, John Lu, Rachel Zwick, Derrick C. Wan, Ophir D. Klein, and Michael T. Longaker. Science Translational Medicine 17 (805): eadk2101.
Psychiatry & Behavioral Neurosciences
Bipolar Disorder: Systematic Review of Approved Psychiatric Medications (2008-2024) and Pipeline Phase-3 Medications. Ramadan, Salma, Laurel Tay, Harlene Kaur, Thomas Parrish, Salma Abdelmoteleb, Jayant Totlani, Emile Tadros, Drew Hirsch, Nathalie Murphy, Ashley Meyer, Macie Miller, Mia Pasini, Aasim Naqvi, Angela Liu, Sabrina Renteria, Rebecca Hedrick, Itai Danovitch, Robert Pechnick, and Waguih William IsHak. Journal of Affective Disorders, June, 119778.
Radiation Oncology
Differential Impact of Left Ventricular Myocardium and Left Coronary Radiation Dose With Incident Heart Failure and Coronary Events in Lung Cancer Radiotherapy. Zhang, Samuel C., Christopher E. Kehayias, Christian Guthier, John He, Jordan O. Gasho, David E. Kozono, Anju Nohria, Andriana Nikolova, Raymond H. Mak, and Katelyn M. Atkins. International Journal of Radiation Oncology, Biology, Physics, June, S0360-3016(25)04493-1.
Duration of Androgen Suppression With Postoperative Radiotherapy (DADSPORT) for Nonmetastatic Prostate Cancer: A Collaborative Systematic Review and Meta-Analysis of Aggregate Data. Burdett, Sarah, David J. Fisher, Jayne F. Tierney, Adrian D. Cook, Daniel E. Spratt, James J. Dignam, Wendy F. Seiferheld, Amar U. Kishan, Yilun Sun, Sylvie Chabaud, Jason A. Efstathiou, Christopher C. Parker, Alan Pollack, Paul Sargos, Igor Latorzeff, Meryem Brihoum, Charles N. Catton, Noel W. Clarke, Felix Y. Feng, Theodore G. Karrison, Pascal Pommier, Howard M. Sandler, Matthew R. Sydes, Claire L. Vale, and DADSPORT Meta-analysis Collaboration. European Urology, June, S0302-2838(25)00291-X.
Surgery
Overcoming Resistance to Immunotherapy by Targeting CD38 in Human Tumor Explants. Revach, Or-Yam, Angelina M. Cicerchia, Ofir Shorer, Claire A. Palin, Boryana Petrova, Seth Anderson, Baolin Liu, Joshua Park, Lee Chen, Arnav Mehta, Samuel J. Wright, Niamh McNamee, Russell W. Jenkins, et al. Cell Reports. Medicine, June, 102210.
Development of an Acute Femoral Hernia Treatment Algorithm: Insights From the ACHQC National Database. Kim, Ian, Galinos Barmparas, and Shirin Towfigh. The American Surgeon, June, 31348251353074.
CORR Insights®: Is Rotationplasty Still a Reasonable Reconstruction Option for Patients With a Femoral Bone Sarcoma? A Comparative Study of Patients with a Minimum of 20 Years of Follow-up After Rotationplasty and Lower Extremity Amputation. Allison, Daniel C. Clinical Orthopaedics and Related Research, June.
Urology
LSP1 Deficiency Increases IL-17-Expressing T Cells and Accelerates Primary Sjögren’s Syndrome. Kim, Jayhyun, Jung Gon Kim, Yingjin Li, Sungyong You, Naeun Lee, and Wan-Uk Kim. Clinical Immunology (Orlando, Fla.), June, 110548.
Open-Source Domain Adaptation to Handle Data Shift for Volumetric Segmentation-Use Case Kidney Segmentation. Correa-Medero, Ramon, Umar Ghaffar, Sam Fathizadeh, Bhavik Patel, Haidar Abdul-Muhsin, and Imon Banerjee. European Radiology, June.
Enzalutamide Treatment of Patients With Advanced Prostate Cancer Across the Disease Spectrum: Plain Language Review. Dato, Paul E., Jose De La Cerda, Andrew J. Armstrong, Arun A. Azad, Ciara Conduit, Gabriel P. Haas, Kenneth Kernen, Zachary W. Klaassen, Raj Patel, Fred Saad, Neal D. Shore, Stephen J. Freedland, and Lawrence I. Karsh. Future Oncology (London, England), June, 1–12.
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