Faculty Publications July 23-31

This week’s edition of Faculty Publications includes Cedars-Sinai studies that were published July 23-31. If you have a published paper from this period that does not appear on this list, please contact Sue Marone.

Cedars-Sinai in the News

Best Hospitals Near Los Angeles | CBS 2
U.S. News & World Report Rankings

NYC Shooter Said Brain Was Damaged by Football | FOX 11
Ray Chu, MD

Medical Expert Discusses the Dangers of Kids and Excessive Screen Time | CBS 2
Jane Tavyev Asher, MD

Cedars-Sinai Physician-Innovator Discusses Virtual Medicine | CBS 2
Omer Liran, MD

Think Checking Your Poop Is Weird? 83% of Americans Do It—And Doctors Approve | Health
Mark Pimentel, MD

Doctors Explain What They Really Think of Biohacking | Prevention
Bert Mandelbaum, MD

Frozen Shoulder Is a Surprising Menopause Side Effect, But Many Women Don't Know About It | Women’s Health
Natasha Trentacosta, MD

Hypothyroidism Linked to Gut Microbiome Disturbances | MDedge GI & Hepatology News
Ruchi Mathur, MD

Faculty Publications

Biomedical Sciences

RNA m6A Modification: A Key Regulator in Normal and Malignant Processes. Zhang, Lianjun, Yidan Lou, Weini Li, Hongshan Guo, Le Xuan Truong Nguyen, and Zhenhua Chen. Cell Investigation 1 (2): 100023.

Expanded Performance Comparison of the Oncuria 10-Plex Bladder Cancer Urine Assay Using Three Different Luminex xMAP Instruments. Tanaka, Sunao, Takuto Shimizu, Ian Pagano, Wayne Hogrefe, Sherry Dunbar, Charles J. Rosser, and Hideki Furuya. Diagnostics (Basel, Switzerland) 15 (14): 1749.

Effective Cerebellar Neuroprosthetic Control After Stroke. Rangwani, Rohit, Aamir Abbasi, and Tanuj Gulati. Cell Reports 44 (8): 116030.

MLH1 c.27G>A (p.Arg9=) Is a Synonymous Likely/Pathogenic Variant Underlying Variably Mosaic Constitutional MLH1 Methylation in Lynch Syndrome. Alvarez, Rocio, Paula Climent-Cantó, GiWon Shin, Francesca Paola Aguirre, Lisa Zhou, Dennis J. Hazelett, Brent K. Larson, Covadonga Vara, Gabriel Capellá, Víctor Lorca Castellanos, Pilar Garre Rubio, Françoise Desseigne, Hanlee Ji, Jackie Cook, Miranda Durkie, Marta Pineda, Julie Leclerc, and Megan P. Hitchins. Familial Cancer 24 (3): 59.

Cardiac Surgery

Ethical Standards in Peer Review of Surgical Practice: Professionalism, Pride, and Prejudice. Roughneen, Patrick T., John W. Entwistle, Robbin G. Cohen, Daniel H. Drake, Brandi Baud Scully, Robert M. Sade, and Cardiothoracic Ethics Forum. The Journal of Thoracic and Cardiovascular Surgery, July, S0022-5223(25)00618-X.

Cardiology

A Deep Learning Phenome Wide Association Study of the Electrocardiogram. Hughes, John Weston, John Theurer, Milos Vukadinovic, Albert J. Rogers, Sulaiman Somani, Guson Kang, Zaniar Ghazizadeh, Jack W. O’Sullivan, Sneha S. Jain, Bruna Gomes, Michael Salerno, Euan Ashley, James Y. Zou, Marco V. Perez, and David Ouyang. European Heart Journal. Digital Health 6 (4): 595–607.

Case Series of Black Athletes Participating in Sports With an Implantable Cardioverter-Defibrillator: Data From the ICD Sports Registry. Chukumerije, Merije T., Brian Olshansky, Elizabeth V. Saarel, David Cannom, Mark S. Link, Michael J. Ackerman, Geliang Gan, and Rachel Lampert. Heart Rhythm O2 6 (7): 1044–46.

Impact of Cancer Subtype and Cancer Therapy Exposures on SARS-CoV-2 Outcomes in the Omicron and Subvariant Era. Atkins, Katelyn M., Minhao Wang, Katrina D. Silos, Sandy Y. Joung, Asneh Singh, Olivia Peony, Jordan O. Gasho, Yeran Lee, Kenia Gastelum, Beatrice Alessandra Filart, Alan C. Kwan, Marilyn Mendez, Yunxian Liu, Patrick Belen, John C. Prostko, Edwin C. Frias, Joseph E. Ebinger, Sonia Sharma, Kimia Sobhani, and Susan Cheng. Cancer Medicine 14 (14): e71082.

Percutaneous Treatment of Multivalvular Heart Disease Following Previous Sternotomy. Ozdemir, Denizhan, Hasan Jilaihawi, Moody Makar, and Raj Makkar. European Heart Journal. Case Reports 9 (7): ytaf317.

Non-Invasive Telemonitoring in Heart Failure: A Systematic Review. Kwaah, Patrick A., Emmanuel Olumuyide, Kassem Farhat, Barbara Malaga-Espinoza, Ahmed Abdullah, Michael H. Beasley, Novi Y. Sari, Lily K. Stern, Julio A. Lamprea-Montealegre, Adrian daSilva-deAbreu, and Jiun-Ruey Hu. Medicina (Kaunas, Lithuania) 61 (7): 1277.

Correlates of Nocturnal Hypertension in a Real-World Cohort. Zhang, Neil, Tzu Yu Huang, Sanket Dhruva, Susan Cheng, and Joseph E. Ebinger. American Journal of Hypertension, July, hpaf135.

Cardiac Enrichment of Mutant Calmodulin Protein in a Murine Model of a Human Calmodulinopathy. Tsai, Wen-Chin, Chiu-Fen Yang, Shu-Yu Lin, Suh-Yuen Liang, Wei-Chung Tsai, Shuai Guo, Xiaochun Li, Susan Ofner, Kai-Chien Yang, Tzu-Ching Meng, Peng-Sheng Chen, and Michael Rubart. JCI Insight, July, e185524.

Modification of the Association of B-Type Natriuretic Peptides With Mortality and Hospitalization Outcomes by Sex. Bobrowski, David, Husam Abdel-Qadir, Candace D. McNaughton, Anna Chu, Xuesong Wang, Peter C. Austin, Barbara S. Doumouras, Karem Abdul-Samad, Peter A. Kavsak, Michael E. Farkouh, James L. Januzzi, Heather J. Ross, and Douglas S. Lee. JACC. Advances 4 (8): 101999.

Prevalence and Phenotype of Transthyretin Val122Ile Variant in the Hispanic Community Health Study/Study of Latinos. Duran-Luciano, Priscilla, Ambarish Pandey, Katrina Swett, Gregory A. Talavera, Martha Daviglus, Barry E. Hurwitz, Sanjiv J. Shah, Tamar Sofer, Scott D. Solomon, Susan Cheng, Larissa Aviles-Santa, Humberto Parada, Bharat Thyagarajan, Franklyn Gonzalez, Mayank M. Kansal, James Tauras, Mathew S. Maurer, and Carlos J. Rodriguez. JACC. Advances 4 (8): 102034.

A Metabolomics Study of Cardiac Dysfunction in Hyperglycemia-Findings From the Atherosclerosis Risk in Communities (ARIC) Study and the Hispanic Community Health Study/Study of Latinos (HCHS/SOL). Yoshida, Yilin, Ngoc Quynh Nguyen, Eun Hye Moon, Casey Rebholz, Hicham Skali, Victoria Arthur, Justin B. Echouffo-Tcheugui, Christie Ballantyne, Elizabeth Selvin, Amil Shah, Robert Kaplan, Carlos J. Rodriguez, Qibin Qi, Susan Cheng, and Bing Yu. Diabetes Care, July, dc250730.

The Authors’ Perspective on ‘Summary of the International Society for Heart and Lung Transplantation Consensus Conference on Emerging Understanding of Antibodies and Antibody-Mediated Rejection in Heart Transplantation.’ Kobashigawa, Jon, Andreas Zuckermann, Adriana Zeevi, Markus J. Barten, Patricia P. Chang, Monica Colvin, Guillaume Coutance, Anne Dipchand, Stephan Ensminger, Marta Farrero, Marlena Habal, Anne Halpin, Annette M. Jackson, Yosef Manla, Kavitha Muthiah, Luciano Potena, Elaine F. Reed, Kelly Schlendorf, Palak Shah, Anat Tambur, Simon Urschel, Steven Webber, Lori West, Jong-Chan Youn, Jignesh Patel, and Consensus Conference participants. The Journal of Heart and Lung Transplantation, 44 (8): 1195–98.

Computational Biomedicine

Prognostication and Treatment Predictions for Estrogen Receptor Positive Early-Stage Breast Cancer: Incorporating the 70-Gene Signature Into the PREDICT Prognostication Model. Engelhardt, Ellen G., Mary Ann E. Binuya, Paul D. P. Pharoah, Coralie Poncet, Emiel J. T. Rutgers, Martine Piccart, Fatima Cardoso, Laura J. van ’t Veer, Ewout W. Steyerberg, Sabine C. Linn, and Marjanka K. Schmidt. Breast (Edinburgh, Scotland) 83 (July): 104542.

Imaging

Patient Perspectives on Artificial Intelligence in Medical Imaging. Glenning, Jeffry, and Lisa Gualtieri. Journal of Participatory Medicine 17 (July): e67816.

Medicine

Navigating Chronic Pancreatitis Pain: A Pathophysiological and Therapeutic Overview. Lin, Zijin, Stephen Pandol, Minoti Apte, and Yi Jiang. Frontiers in Physiology 16: 1622845.

Immunosuppression in Lung Transplantation: Current and Emerging Therapies. Barnes, Darina, Rahila Ogunnaike, Lauren Shitanishi, and Reinaldo Rampolla. Current Pulmonology Reports 14 (1): 12.

Bridge to Lung Transplantation Utilizing Extracorporeal Membrane Oxygenation: Consensus and Controversies. Yuen, Alexander, Laura DiChiacchio, Pedro Catarino, Dominick Megna, and Reinaldo Rampolla. Current Pulmonology Reports 14 (1): 13.

Early Detection of Pancreatic Cancer: Current Advances and Future Opportunities. Lin, Zijin, Esther A. Adeniran, Yanna Cai, Touseef Ahmad Qureshi, Debiao Li, Jun Gong, Jianing Li, Stephen J. Pandol, and Yi Jiang. Biomedicines 13 (7): 1733.

Anti-TL1A Antibody, Afimkibart, in Moderately-to-Severely Active Ulcerative Colitis (TUSCANY-2): A Multicentre, Double-Blind, Treat-through, Multi-Dose, Randomised, Placebo-Controlled, Phase 2b Trial. Danese, Silvio, Jessica R. Allegretti, Stefan Schreiber, Laurent Peyrin-Biroulet, Vipul Jairath, Geert D’Haens, Jarosław Kierkuś, Rupert W. Leong, Andres J. Yarur, Michael S. Vincent, Anindita Banerjee, Deepa E. Chandra, Elena Peeva, Srividya Neelakantan, Kenneth E. Hung, Jacqueline M. McBride, Daniela Bojic, Karen Lasch, Courtney Schiffman, and Brian G. Feagan. The Lancet. Gastroenterology & Hepatology, July, S2468-1253(25)00129-3.

A Core Outcome Set for Pituitary Surgery Research: An International Delphi Consensus Study. Valetopoulou, Alexandra, Nicola Newall, Danyal Z. Khan, Anouk Borg, Pierre M. G. Bouloux, Fion Bremner, Michael Buchfelder, Simon Cudlip, Neil Dorward, William M. Drake, Juan C. Fernandez-Miranda, Maria Fleseriu, Mathew Geltzeiler, Joy Ginn, Mark Gurnell, Steve Harris, Zane Jaunmuktane, Márta Korbonits, Michael Kosmin, Olympia Koulouri, Hugo Layard Horsfall, Adam N. Mamelak, Richard Mannion, Pat McBride, Ann I. McCormack, Shlomo Melmed, Katherine A. Miszkiel, Gerald Raverot, Thomas Santarius, Theodore H. Schwartz, Inma Serrano, Gabriel Zada, Stephanie E. Baldeweg, Hani J. Marcus, Angelos G. Kolias, and PitCOP Collaborators. Pituitary 28 (4): 88.

First-in-Human Phase 1/2 Study of INCAGN01876, a Glucocorticoid-Induced Tumor Necrosis Factor Receptor Agonist, in Patients With Advanced or Metastatic Solid Tumors. Hamid, Omid, Dana B. Cardin, F. Stephen Hodi, Patricia LoRusso, Taha Merghoub, Roberta Zappasodi, Rachana Maniyar, John E. Janik, Maikel V. W. van der Velden, Feng Zhou, Zhiwan Dong, Xuejun Chen, and James J. Harding. Clinical Cancer Research, July.

Managing Hepatocellular Carcinoma Recurrence After Liver Transplantation: Emerging Role of Immune Checkpoint Inhibitors. Rezaee-Zavareh, Mohammad Saeid, Soo Young Hwang, Naomy Kim, Hasmik Adetyan, Nguyen H. Tran, and Ju Dong Yang. Discover Oncology 16 (1): 1431.

Response by Hijazi et al to Letter Regarding Article, ‘Deep Learning-Derived Cardiac Chamber Volumes and Mass From PET/CT Attenuation Scans: Associations With Myocardial Flow Reserve and Heart Failure.’ Hijazi, Waseem, Aakash Shanbhag, Robert J. H. Miller, and Piotr J. Slomka. Circulation. Cardiovascular Imaging, July, e018683.

Menopause Factors and Alterations in Gut Microbiota and Insulin Homeostasis: A Cross-Sectional Analysis of the Microbiome and Insulin Longitudinal Evaluation Study (MILES). Maffei, Vincent J., Alain G. Bertoni, Alexis C. Wood, Jerome I. Rotter, Osa Crago, Yii-Der I. Chen, Joseph F. Petrosino, Kristi L. Hoffman, Mark O. Goodarzi, and Elizabeth T. Jensen. Diabetes, Obesity & Metabolism, July.

Neurology

Marcelle Lapicque (1873-1960): The First Black Female European Neuroscientist? Christy, Alison, Manon Auffret, Jean-Gaël Barbara, and Alexis Simpkins. Journal of the National Medical Association, July, S0027-9684(25)00088-4.

Concordance Between Amyloid-PET Quantification and Real-World Visual Reads. Zeltzer, Ehud, Daniel R. Schonhaut, Nidhi S. Mundada, Ganna Blazhenets, David N. Soleimani-Meigooni, Hanna Cho, Kamalini G. Ranasinghe, Charles Windon, Golnaz Yadollahikhales, Charles Apgar, Constantine Gatsonis, Maria C. Carrillo, Lucy Hanna, Justin Romanoff, Bruce E. Hillner, Robert A. Koeppe, Andrew March, Barry A. Siegel, Karen Smith, Rachel A. Whitmer, Leonardo Iaccarino, Gil D. Rabinovici, and Renaud La Joie. JAMA Neurology, July, e252218.

Orthopaedics

Midterm Outcomes Following Conversion of Failed Ankle Arthrodesis to Total Ankle Arthroplasty, Including Patients With a Deficient Fibula. Lian, George, William Ip, Andrea Hankins, Michele Guillen, and Carol Parise. Foot & Ankle Orthopaedics 10 (3): 24730114251351636.

Pathology and Laboratory Medicine

Clinicopathologic Characteristics of Intraglomerular Malignancy in Kidney Biopsies. Lee, Chen Yu Jamie, Cynthia C. Nast, Jean Hou, Mark Haas, Mercury Y. Lin, Michifumi Yamashita, and Hae Yoon Grace Choung. Glomerular Diseases 5 (1): 304–15.

Multi-Center Validation of Video-Based Deep Learning to Evaluate Defecation Patterns on 3D High-Definition Anorectal Manometry. Azher, Zarif, Brian D. Ginnebaugh, David Justin Levinthal, Nelson Valentin, Joshua J. Levy, and Dinesh Shah Eric. Clinical Gastroenterology and Hepatology, July, S1542-3565(25)00630-5.

Pediatrics

Impact of Precision-Guided Dosing on Clinical Decision-Making and Health Care Utilization in Inflammatory Bowel Disease: A Retrospective Pretest/Posttest Real-World Study. Arai, Ronen, Adria Condino, Bincy P. Abraham, Stephen B. Hanauer, Udayakumar Navaneethan, Donald Lum, Syed A. Hassan, Timothy Ritter, Esther A. Torres, David Ziring, Harry Bray, Thierry Dervieux, Patricia Aragon Han, and Terrence A. Barrett. Crohn’s & Colitis 360 7 (3): otaf044.

Touchless Monitoring of Neonatal Activity: A Multi-Center Study. Addison, Paul S., Mridula Gunturi, Dean Montgomery, Rangasamy Ramanathan, Manoj A. Biniwale, Dale Gerstmann, Jeffrey Clemmer, and Rena Nelson. Pediatric Research, July.

Evaluation of Biventricular Diastolic Function in Preterm Infants in the First Week of Postnatal Life. Sierra-Strum, Ivonne, Rutuja Kibe, Piyawat Arichai, Hemananda Muniraman, Ebrahimi Mahmood, Rowena Cayabyab, Yogen Singh, and Rangasamy Ramanathan. Pediatric Cardiology, July.

Psychiatry & Behavioral Neurosciences

Insights and Considerations for the START Trial and Managing Opioid Use Disorder-Reply. Ober, Allison J., Cristina Murray-Krezan, and Itai Danovitch. JAMA Internal Medicine, July.

Radiation Oncology

High-Dose-Rate (HDR) Brachytherapy Boost in Combination With External Beam Radiotherapy for Localized Prostate Cancer: An Evidence-Based Consensus Statement. Patel, Sagar A., Marisa Kollmeier, Juanita Crook, Daniel Krauss, Gerard Morton, Albert J. Chang, Joelle Helou, I.-Chow Hsu, Cynthia Menard, Shyamal Patel, Tyler Robin, Peter J. Rossi, Michael J. Zelefsky, and Mitchell R. Kamrava. Brachytherapy, July, S1538-4721(25)00117-5.

Phase III Trial of Dose Escalated Radiation Therapy and Standard Androgen Deprivation Therapy (ADT) vs. Dose Escalated Radiation Therapy and Enhanced ADT With Orteronel for Men With High-Risk Prostate Cancer (NRG/RTOG 1115). Hamstra, Daniel A., James J. Dignam, Deborah W. Bruner, M. Dror Michaelson, François Bachand, Viraj Master, Mylin A. Torres, Philip J. Saylor, Robert E. Wallace, Neha Vapiwala, Jason A. Efstathiou, Mack Roach, Seth A. Rosenthal, Adam Raben, Scott C. Morgan, Vivek S. Kavadi, Daniel E. Spratt, Jeff M. Michalski, Wendy Seiferheld, Stephanie L. Pugh, Benjamin Movsas, and Howard Sandler. International Journal of Radiation Oncology, Biology, Physics, July, S0360-3016(25)06022-5.

Surgery

Ectopic Presentation of Hidradenitis Suppurativa on the Dorsal Foot With Secondary Bacterial Infection: A Case Report. Carrillo-Kashani, Alexander, Moamen Elhaddad, Jacob Stibelman, and B. David Massaband. SKIN The Journal of Cutaneous Medicine 9 (4): 2533–38.

Improvement in Functional Outcomes Following Ileal Pouch-Anal Anastomosis: Results From the United States Ileal Pouch-Anal Anastomosis Study. Zuckerman, Jesse, Anthony de Buck van Overstraeten, Gil Y. Melmed, William Conan Mustain, Jeffrey S. Scow, Mary Otterson, James Ogilvie, Liliana Bordeianou, Mantaj Brar, Katerina Wells, Gayane Ovsepyan, James Mirocha, Stefan D. Holubar, Steven Wexner, Neil Hyman, Phillip Fleshner, and Karen Zaghiyan. Diseases of the Colon and Rectum, July.

Urology

Survival Benefit Associated With First-Line Androgen Receptor Pathway Inhibitors for de Novo Metastatic Castration-Sensitive Prostate Cancer. Freedland, Stephen J., Agnes Hong, Nader El-Chaar, Amanda M. De Hoedt, Janet Kim, Claire Evans, Joshua A. Parrish, Maelys Touya, Krishnan Ramaswamy, Lin Gu, and Thomas J. Polascik. Prostate Cancer and Prostatic Diseases, July.

Cedars-Sinai Health Sciences University is advancing groundbreaking research and educating future leaders in medicine, biomedical sciences and allied health sciences. Learn more about the university.