Faculty Publications Dec. 4-11

This week’s edition of Faculty Publications includes Cedars-Sinai studies that were published Dec. 4-11. If you have a published paper from this period that does not appear on this list, please contact Sue Marone.

Cedars-Sinai in the News

Doctors Deliver Baby While Removing 22-Pound Tumor From Mother: 'Medical Miracle' | Good Morning America | NBC4 Los Angeles | Telemundo
John Ozimek, DO; Michael Manuel, MD; Michael Sanchez, MD; Sarah J. Kilpatrick, MD, PhD; Sara Dayanim, MD

At-Home Alzheimer’s Tests Are Here | AARP
Zaldy Tan, MD, MPH

The Biggest Breakthroughs in Cell Biology in 2025 | The Scientist
Ophir Klein, MD, PhD

Does Fertility Really Drop Off at 35? No, It Doesn’t. So Why all the Focus on That Age? | Laist/Air Talk
Mariam Naqvi, MD

Coffee and AFib, Oral PCSK9 Drugs, an HFrEF Polypill, and Vitamin D Post-MI: Highlights From AHA 2025 | JAMA Network
Joanna Chikwe, MD

New Device Uses Steam to Kill Prostate Cancer | Medscape
Adam Weiner, MD

First-Ever Drug to Repair DNA and Regenerate Damaged Tissue is Here | News Atlas
Eduardo Marbán, MD, PhD; Ahmed Ibrahim, MD, PhD

Cedars-Sinai and Exobiosphere Partner to Launch Biomedical Research Aboard the Vast Haven-1 Space Station | Space Daily
Arun Sharma, PhD; Maedeh Mozneb, PhD; Nirdesh Gupta, PhD

The Battle Against Resistant Hypertension: New Guidelines, Drugs and Treatment Options | Healio Cardiology Today
Florian Rader, MD

Want to Walk While Working? Experts Recommend This Standing Desk and Treadmill Combo | Women’s Health
Andrew J. Bach, DO

Faculty Publications

Anesthesiology

Growing Market for Pain-Related Medical Devices: What Anesthesia and Pain Providers Can Learn From the Open Payments Database. Klein, Julia Isabella, Mishan D. Rambukwella, Kathy S. Cazares, Tristan Grogan, and Dane A. Saksa. Regional Anesthesia and Pain Medicine, December, rapm-2025-107422.

Biomedical Sciences

The Family Experience of the Invictus Games Through a Work Family Conflict Lens: An Interpretative Phenomenological Analysis. Roberts, Lauren Stephanie, Celina H. Shirazipour, Deborah Norris, and Heidi Cramm. Family Court Review 63 (4): 715–27.

The Association of Artificial Intelligence-Enabled Coronary Plaque Analysis With Future Non-ST Elevation Myocardial Infarction. Chen, Lu Q., Caroline Park, Andrew Lin, Emily Xing, Ruqiyya Bano, Jonathan Weber, Jonathan Scheiner, Michael Shearer, Aviva Landau, Anna Tsioulias, Carmela Musso, Kathleen Rapelje, Damini Dey, and J. Jane Cao. Coronary Artery Disease 37 (1): 1–7.

Cardiac Surgery

Concomitant Surgical Ablation Using a Novel Bipolar Radiofrequency Clamp: Outcomes From the TRAC-AF Registry. Shults, Christian, Armin Kiankhooy, Shaf B. Holden, Hetal D. Patel, Frans van Wagenberg, Gansevoort H. Dunnington, Andres Samayoa, Theodore Wright, Andrew J. Sherman, Eric Sievers, Aaron Kime, Jeffrey Newman, Andrew Barksdale, Joshua N. Baugh, Yasir Abu-Omar, Gregory Rushing, Marc Gerdisch, and TRAC-AF Investigators. Journal of Clinical Medicine 14 (23): 8360.

Current Approaches to Minimally Invasive Lung Transplantation-a Technical Guide. Catarino, Pedro, Stephanie H. Chang, Dominic Emerson, Dominick J. Megna, Travis C. Geraci, Eugene A. Grossi, Caitlin T. Demarest, John Stokes, and Konrad Hoetzenecker. JTCVS Techniques 34 (December): 295–302.

Cardiology

Reappraising Intravesical Gemcitabine in BCG-Unresponsive Nonmuscle-Invasive Bladder Cancer: Lessons From Contemporary Re-Analysis. Taj, Javeria, Niharika Ikkurthy, and Joshua Ekouo. Annals of Medicine and Surgery (2012) 87 (12): 9189–90.

The Role of Bioactive Lipids and Eicosanoid Metabolites in Acute Exercise in Adults: Insights Into Human Cardiorespiratory Fitness. Ambatipudi, Mythri, Athar Roshandelpoor, J. Sawalla Guseh, Leah B. Kosyakovsky, Mona Alotaibi, Susan Cheng, Mohit Jain, Gregory D. Lewis, and Jennifer E. Ho. Physiological Reports 13 (23): e70671.

Methodological Appraisal of Ongoing Trial of Transcatheter Aortic Valve Implantation Versus Surgical Aortic Valve Replacement in Younger Patients: From Incentives to Guideline-Informing Evidence. Milojevic, Milan, Patrick O. Myers, Volkmar Falk, Joseph E. Bavaria, Michael A. Borger, Filip P. A. Casselman, Vinay Badhwar, Sanjay Kaul, Matthias Siepe, and J. Rafael Sadaba. European Journal of Cardio-Thoracic Surgery, 67 (12): ezaf348.

Dual Assessment of CAC and Exercise Ability Enhances Mortality Prediction in Stress SPECT-MPI Patients. Fujito, Hidesato, Heidi Gransar, Rebekah H. Park, Donghee Han, Robert J. H. Miller, Alan C. Kwan, Sean W. Hayes, Piotr J. Slomka, Damini Dey, John D. Friedman, Daniel S. Berman, and Alan Rozanski. Journal of Nuclear Cardiology, December, 102582.

Heart Allograft Rejection: Molecular Diagnosis Using Intra-Graft Targeted Gene Expression Profiling. Giarraputo, Alessia, Guillaume Coutance, Jignesh K. Patel, Marny Fedrigo, Olivier Aubert, Shaida Varnous, Ilaria Barison, Chiara Castellani, Jean Paul Duong Van Huyen, Jessy Dagobert, Fariza Mezine, Blaise Robin, Dina Zielinski, Philippe Rouvier, Pascal Leprince, Paul Achouh, Gino Gerosa, Virginie Verkarre, Xavier Jouven, Patrick Bruneval, Annalisa Angelini, Jon Kobashigawa, and Alexandre Loupy. European Heart Journal, December, ehaf949.

Mitral Transcatheter Edge-to-Edge Repair in Patients With Severe Pulmonary Hypertension. Shechter, Alon, Aakriti Gupta, Danon Kaewkes, Homa Taheri, Takashi Nagasaka, Vivek Patel, Kazuki Suruga, Keita Koseki, Ofir Koren, Moody Makar, Sabah Skaf, Dhairya Patel, Tarun Chakravarty, Robert J. Siegel, and Raj R. Makkar. Clinical Research in Cardiology, December.

Statin-Induced Decade-Long Stabilization of Noncalcified Coronary Plaque Despite a Zero Calcium Score. Karlsberg, Ronald P. JACC. Case Reports, December, 106400.

Stress Cardiac Magnetic Resonance Ischemia Burden and Cardiovascular Events: Post-Hoc Analysis From the ISCHEMIA Trial. Kwong, Raymond Y., Bobby Heydari, Siddique Abbasi, Francois-Pierre Mongeon, Francois Marcotte, Matthias Friedrich, Leslee J. Shaw, Yifan Xu, Rebecca Anthopolos, Raffi Bekeredjian, Lorenzo Monti, Joseph Selvanayagam, Maciej Lesiak, Michael H. Picard, Daniel S. Berman, Sripal Bangalore, John A. Spertus, Gregg W. Stone, William E. Boden, James Min, G. B. John Mancini, Jonathan Leipsic, Matthew Budoff, Cameron Hague, Judith S. Hochman, David J. Maron, Harmony R. Reynolds, and ISCHEMIA Research Group. JACC. Cardiovascular Imaging, December, S1936-878X(25)00597-2.

Hemolysis Detected Following the Preparation and Collection of Blood in a Porcine Model Using a Syringe-Based Aspiration Thrombectomy System for Autotransfusion. Dohad, Suhail, Mohammed M. Hoque, Jonathan H. Waters, and Marc Salhanick. Catheterization and Cardiovascular Interventions, December.

Sex Differences in Cardiac Ageing: From Clinical Curiosity to Scientific Sagacity. Ji, Hongwei, Jennifer E. Ho, and Susan Cheng. European Heart Journal, December, ehaf736.

Computational Biomedicine

Uncovering Dental Caries Heterogeneity in NHANES Using Machine Learning. Orlenko, A., J. D. Mure, J. I. Gluch, J. Gregg, C. W. Compher, Z. Ren, H. Koo, and J. H. Moore. Journal of Dental Research, December, 220345251398027.

Medicine

Clinical Features, Management, and Outcomes of Right Heart Thrombi: A Retrospective Cohort Study. Fritzmann, Emily, Alexander D. Yuen, Stephanie Chang, Maidah Yaqoob, April Kinninger, Jina Chung, Janine R. E. Vintch, and Yuri Matusov. Thrombosis Research 257 (November): 109557.

Early and Late Myocardial Effects of Proton Beam Cardiac Radioablation: Insights From Gene Expression Analysis. Hirao, Tatsuhiko, Masayoshi Suda, Maryam E. Rettmann, Amanda J. Deisher, John A. Wight, Taro Koya, Laura K. Newman, Tamar Tchkonia, Jon J. Kruse, Dean A. Shumway, Kenneth W. Merrell, Samuel J. Asirvatham, James L. Kirkland, Douglas L. Packer, and Konstantinos C. Siontis. JACC. Clinical Electrophysiology, December, S2405-500X(25)00894-1.

Local Interactions Between Innate Immune Signaling, Microbiota, and Bile Acids Drive the Development of Duodenal Adenomas. Burgueño, Juan F., Hajar Hazime, Julia Fritsch, Gillian E. Jacobsen, Henry D. Dione, Trevor Cickovski, Eddy E. González, Ana M. Santander, Irina Fernández, Nivis Brito, Zhen Gao, Yuguang Ban, Lily Wang, Landon Wilson, Stephen Barnes, Judith Pignac-Kobinger, Mark S. Sundrud, and Maria T. Abreu. Cellular and Molecular Gastroenterology and Hepatology, December, 101694.

Proinflammatory GSDMD Activation in Live Macrophages and DLBCL Cells Marks Cognate Interactions and Better Prognosis. Kong, Xue, Zijun Y. Xu-Monette, Zhenming Xu, Eric Hsi, Xiaoxian Zhao, Hui Yan, Harry Nunns, Kelly Au, Carlo Visco, Alexandar Tzankov, Karen Dybkaer, Shuna Yao, Dehong Wu, Chang Wang, Alexander M. Xu, Zenggang Pan, Benjamin M. Parsons, April Chiu, Wayne Tam, Santiago Montes-Moreno, Fenghuang Zhan, Leon Bernal-Mizrachi, Youli Zu, Shanxiang Zhang, Michael Boe Møller, Weina Chen, Qingyan Au, Akil A. Merchant, Govind Bhagat, Yong Li, and Ken H. Young. Blood Advances, December, bloodadvances.2025017643.

Circulating Tumor Cell and Oncosome Subtypes in Portal and Peripheral Venous Circulations May Be Used for Diagnosis and Prognostication of Pancreatic Cancer. Shishido, Stephanie N., Divya Suresh, Jeremy Mason, Quin Liu, Kenneth Park, Rabindra Watson, Nicholas Nissen, Srinivas Gaddam, Simon K. Lo, Stephen Pandol, and Peter Kuhn. NPJ Precision Oncology, December.

Kidney Biorepositories: Valuable Tools Advancing Acute Kidney Injury Research. Gewin, Leslie S., Chirag Parikh, Sanjay Jain, Adriana Hung, Amandeep Bajwa, Mark Okusa, Sanjeev Kumar, and Sherry G. Mansour. Kidney360, December.

Placental Expression of GKN1 and Diminished Pancreatic Beta Cell Function During Pregnancy. Powe, Camille E., Frederique White, Catherine Allard, Lydia Shook, Andrea Edlow, Luigi Bouchard, Francois Aguet, Pierre-Etienne Jacques, Kristin Ardlie, Jose C. Florez, S. Ananth Karumanchi, and Marie-France Hivert. Diabetologia, December.

Etiology of Cirrhosis Is Associated With Risk of Hepatic Decompensation and Hepatocellular Carcinoma. Ng, Michelle, Olgert Bardhi, Krystal Lai, Eden Koo, Sruthi Yekkaluri, Kevin Bass, Guruveer Bhamra, Pojsakorn Danpanichkul, Lisa Quirk, Ju Dong Yang, Jeremy Louissaint, Thomas A. Kerr, and Amit G. Singal. BMC Gastroenterology, December.

Pathophysiology and Management of Right Ventricular Failure in Critically Ill Patients: A Narrative Review. Kermanian, Riley, Harpreet Dosanjh, Michael I. Lewis, and Yuri Matusov. World Journal of Critical Care Medicine 14 (4): 111434.

Effect of Fasting-Mimicking Diet on Markers of Autophagy and Metabolic Health in Human Subjects. Espinoza, Sara E., Sue Park, Gavin Connolly, Wenbo Qi, Ning Zhang, Manpreet Semwal, Yan Li, Marie Lauzon, Adam B. Salmon, William Hsu, Min Wei, and Nicolas Musi. GeroScience, December.

Neurosurgery

Return to Activity for On- and Off-Label Cervical Arthroplasty Patients: A Multicentered Expert Panel Recommendation. Ament, Jared D., Amir Vokshoor, Jack Petros, Tina Zabehi, Armen Khachatryan, Matthew Scott-Young, J. Alex Sielatycki, Rick C. Sasso, Jason M. Cuéllar, Jack Zigler, Richard D. Guyer, Scott Blumenthal, and Todd Lanman. International Journal of Spine Surgery, December, 8834.

OBGYN

Vaginal Hysterectomy vs Laparoscopic Hysterectomy for Benign Indications: Complications and Length of Stay in a National Analysis of Contemporary Data. Meyer, Raanan, Kacey M. Hamilton, Ogechukwu Ezike, Katharine Ciesielski, Diamond Goodwin, Rebecca J. Schneyer, Yael Yagur, Nir Horesh, Gabriel Levin, Matthew T. Siedhoff, and Kelly N. Wright. American Journal of Obstetrics and Gynecology, October, S0002-9378(25)00776-8.

Pathology and Laboratory Medicine

Combined Inhibition of NAD Synthesis and C-Terminal Binding Protein Cooperatively Induces Cell Death and Inhibits Growth of High Grade Serous Ovarian Carcinoma. Chougoni, Kranthi Kumar, Jacqueline West, Nicholette St Martin, Diana Dcona, Istem Kose, Nari Kim, Martin M. Dcona, Ronny Drapkin, Joseph W. Carlson, Ann E. Walts, Sandra Orsulic, Keith C. Ellis, and Steven R. Grossman. Scientific Reports, December.

Physical Medicine & Rehabilitation

Comparing Functional Response in Patients With and Without COVID-19 Admitted to Inpatient Rehabilitation: A Retrospective Study. Roberts, Pamela, Debra Ouellette, Jeffrey Wertheimer, Mary Nasmyth, and Gabrielle DeLauter. American Journal of Physical Medicine & Rehabilitation 104 (12): 1140.

Psychiatry & Behavioral Neurosciences

How Is Diversity Integrated in Continuing Education? Results From a Mixed Methods Study. Oberleitner, Lindsay M. S., Jennifer M. Taylor, Christopher G. AhnAllen, Robert A. Chernoff, Carl E. Isenhart, Kristen Knight-Griffin, Bruce S. Liese, Greg J. Neimeyer, Danielle Rynczak, and Hideko Sera. Practice Innovations.

Behavioral Design for Reducing Alcohol Consumption in Aging: A Mobile Messaging Randomized Controlled Trial. Sobolev, Michael, Patrycja Sleboda, Beatriz Torre, Fred Muench, and Alexis Kuerbis. Journal of Substance Use and Addiction Treatment, December, 209856.

Radiation Oncology

Safety of Combining Radiation Therapy and Antibody Drug Conjugates in Advanced Urothelial and Other Cancers. Lock, Derrick, Yash S. Soni, Lindsay Hwang, Suzanne Cole, Anishka D’Souza, Aurelie Garant, Daniel X. Yang, Waddah Arafat, Tian Zhang, Leslie K. Ballas, and Neil B. Desai. Advances in Radiation Oncology 11 (1): 101926.

Surgery

ASO Visual Abstract: Surgical Oncologists for Sustainability-A Statement From the SSO Surgical Oncologists for Sustainability Committee. Gabriel, Emmanuel M., Kathryn T. Chen, Miral Amin, Rebecca Ann Craufurd Auer, Ricardo Julio Bello, Russell S. Berman, Pam Hayden, Kayleigh Herrick-Reynolds, Tari A. King, Ioannis T. Konstantinidis, Kayla Laraia, Gary N. Mann, Corbin Morris, Colette Pameijer, Ranjna Sharma, Georgios Tsoulfas, Jaeyun Jane Wang, and E. Shelley Hwang. Annals of Surgical Oncology, December.

Evolving Use of Circulating Tumor DNA for HPV+ Oropharyngeal Carcinoma: Consensus Recommendations From the California Head and Neck Consortium. Ho, Allen S., Justin T. Moyers, Shirin Attarian, Rupali Banker, Andrew Birkeland, Michelle M. Chen, Charles S. Coffey, Theresa Guo, Yarah Haidar, Jeremy P. Harris, F. Christopher Holsinger, Jared Inman, Julie K. Jang, Niels Kokot, Daniel Kwon, Andrew Larson, Alice Lin, Ellie Maghami, Jon Mallen-St Clair, Abie Mendelsohn, Alain C. Mita, William R. Ryan, Maie St John, Sagus Sampath, Kevin S. Scher, Uttam Sinha, Liyang Tang, Jacob Thomas, Tjoson Tjoa, Katherine C. Wai, Evan S. Walgama, Deborah J. Wong, and Zachary S. Zumsteg. JCO Oncology Practice, December, OP2500450.

Rs10204525 Binding to miR-4717-3p Modulates PD-1 Expression and Predicts the Development of Immune-Related Adverse Events in Patients With Advanced Cancer Treated With Anti-PD-1/PD-L1 Therapy. Polcaro, Giovanna, Luigi Liguori, Valentina Manzo, Emanuela De Bellis, Berenice Stefanelli, Valentina Pagliara, Maddalena Langella, Alessandro Caputo, Alessandro Ottaiano, Rosanna Martinelli, Marco Cascella, Cristina Ferrone, Amelia Filippelli, Valeria Conti, Stefano Pepe, and Francesco Sabbatino. Journal for Immunotherapy of Cancer 13 (12): e012207.

Long-Term Outcomes of Spleen-Preserving Distal Pancreatectomy With or Without Preservation of Splenic Vessels: A Bi-Institutional Experience. Arya, Shahrzad, Marco Ventin, Liti Zhang, Carlos Fernandez-Del Castillo, Alexandra Gangi, Nicholas Nissen, Kambiz Kosari, Giulia Cattaneo, Motaz Qadan, Keith D. Lillemoe, Andrew L. Warshaw, and Cristina R. Ferrone. Annals of Surgery, December.

Urology

Developing a Prediction Model in a Large Case-Control Study for the Early Detection of Bladder Cancer. Tanaka, Sunao, Lynne R. Wilkens, Loïc Le Marchand, Gong Yang, Jian-Min Yuan, Woon-Puay Koh, Martha J. Shrubsole, Michael Luu, Ian Pagano, Jane C. Figueiredo, Hideki Furuya, and Charles J. Rosser. Journal of Translational Medicine, December.

Differential Microglial Responses to Structurally Distinct Alpha-Synuclein Polymorphs. Chang, Katherine, Jina Kim, Michiyo Iba, Jae-Hyeon Park, Alexandria Beilina, Zulfeqhar A. Syed, Valentina Baena, Liam Horan-Portelance, Mark R. Cookson, Sungyong You, and Changyoun Kim. Molecular Brain, December.

Enzalutamide Monotherapy for the Treatment of Prostate Cancer With High-Risk Biochemical Recurrence: EMBARK Secondary Endpoints. Shore, Neal D., Ugo De Giorgi, Ronald F. Tutrone, James L. Bailen, Erik Pm Roos, Ján Kliment, Gavin Marx, Lawrence I. Karsh, Miguel Ramirez-Backhaus, Edward M. Uchio, Stéphane Supiot, Yiyun Tang, Brad Rosbrook, Gabriel P. Haas, Matt Rosales, Fabian Zohren, Jamal Tarazi, and Stephen J. Freedland. The Journal of Urology, December, 101097JU0000000000004879.

Characterizing Population-Wide Genomic Risk Distribution for Development of a Novel Clinical-Genomic Risk System for Prognostication in Patients With Clinically Localized Prostate Cancer. Singhal, Udit, Ralph Jiang, James A. Proudfoot, Elizabeth Chase, Krithika Suresh, Elai Davicioni, Tudor Borza, Michael J. Zelefsky, Brian J. Davis, Brad J. Stish, R. Jeffrey Karnes, Stephen J. Freedland, Martha K. Terris, William J. Aronson, Matthew R. Cooperberg, Fabio Y. Moraes, Alejandro Berlin, Curtiland Deville, Nicholas G. Zaorsky, Soumyajit Roy, Angela Y. Jia, Jonathan E. Shoag, William C. Jackson, Daniel E. Spratt, Matthew Schipper, Todd M. Morgan, and Robert T. Dess. Prostate Cancer and Prostatic Diseases, December.

Treatment of High-Risk Biochemically Recurrent Prostate Cancer With Enzalutamide in Combination With Leuprolide: Secondary Endpoints From the EMBARK Trial. Shore, Neal D., Martin Gleave, Ugo De Giorgi, Antti Rannikko, Christopher M. Pieczonka, Swetha Sridharan, Klaus Brasso, Henry H. Woo, Antonio Gómez Caamaño, Jeff W. Saranchuk, Luke T. Nordquist, Ubirajara Ferreira, Yiyun Tang, Brad Rosbrook, Gabriel P. Haas, Matt Rosales, Fabian Zohren, Jamal Tarazi, and Stephen J. Freedland. The Journal of Urology, December, 101097JU0000000000004890.

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