Faculty Publications Aug. 22-29
A Comprehensive Digest of Research Publications From Cedars-Sinai Investigators
This week’s edition of Faculty Publications includes Cedars-Sinai studies that were published Aug. 22-29. If you have a published paper from this period that does not appear on this list, please contact Sue Marone.
Biomedical Sciences
Incremental Prognostic Value of Coronary Hyper-Intensity Plaque on Non-Contrast Cardiac Magnetic Resonance With Global Longitudinal Strain for Major Adverse Cardiac Events in Patients With Acute Coronary Syndrome. Sun, Yumeng, Wen Liu, Haiyang Xu, Lu Li, Tingting Li, Zhenjia Wang, Wei Yu, Yibin Xie, and Debiao Li. Academic Radiology, August, S1076-6332(24)00593-2.
Rare Germline Genetic Variation in PAX8 Transcription Factor Binding Sites and Susceptibility to Epithelial Ovarian Cancer. Ezquina, Suzana A. M., Michelle Jones, Ed Dicks, Amber de Vries, Pei-Chen Peng, Kate Lawrenson, Rosario I. Corona, Jonathan Tyrer, Dennis Hazelett, James Brenton, Antonis Antoniou, Simon A. Gayther, and Paul D. P. Pharoah. American Journal of Epidemiology, August, kwae301. (September): 100711.
Cardiac Surgery
Guidelines Versus Practice: Surgical Versus Transcatheter Aortic Valve Replacement in Adults < 60 Years. Alabbadi, Sundos, Jad Malas, Qiudong Chen, Wen Cheng, Derrick Y. Tam, Robbin G. Cohen, Michael E. Bowdish, Natalia Egorova, and Joanna Chikwe. The Annals of Thoracic Surgery, August, S0003-4975(24)00671-4.
Current Practices in the Management of Temporary Mechanical Circulatory Support: A Survey of CICU Directors in North America. Balgobind, Amrita, Matthew Pierce, Carlos Alviar, Christopher Barnett, Gregory Barsness, Sunit-Preet Chaudhry, Meshe Chonde, Howard Cooper, Lori Daniels, Umesh Gidwani, Christopher Fordyce, Michael Goldfarb, Jason N. Katz, Michael Kontos, Younghoon Kwon, Evan Liebner, Shuangbo Liu, P. Elliott Miller, L. K. Newby, Connor O’Brien, Alexander Papolos, Barbara Pisani, Brian Potter, Alastair Proudfoot, Robert O. Roswell, Shashank S. Sinha, Timothy D. Smith, Andrea D. Thompson, Sean van Diepen, Sammy Zakaria, David Morrow, and Miguel Alvarez Villela. American Heart Journal 276 (October): 115–19.
Cardiology
Myocardial Ultrastructure of Human Heart Failure With Preserved Ejection Fraction. Meddeb, Mariam, Navid Koleini, Aleksandra Binek, Mohammad Keykhaei, Reyhane Darehgazani, Seoyoung Kwon, Celia Aboaf, Kenneth B. Margulies, Ken C. Bedi, Mohamed Lehar, Kavita Sharma, Virginia S. Hahn, Jennifer E. Van Eyk, Cinthia I. Drachenberg, and David A. Kass. Nature Cardiovascular Research 3 (8): 907–14.
Frailty and Clinical Outcomes of Ticagrelor Versus Clopidogrel in Older Adults With Acute Myocardial Infarction. Ko, Darae, Peter T. Evans, Kueiyu Joshua Lin, Ashvin N. Pande, Alexander Cervone, Su Been Lee, Susan Cheng, Theodore Tsacogianis, Robert J. Glynn, and Dae Hyun Kim. Journal of the American Heart Association 13 (15): e034529.
Antihypertensive Medication Prescription Dispensation Among Pregnant Women in the United States: A Cohort Study. Chen, Melanie T., Brandi L. Vollmer, C. Adair Blyler, Natalie A. Cameron, Eliza C. Miller, Yongmei Huang, Alexander M. Friedman, Jason D. Wright, Amelia K. Boehme, and Natalie A. Bello. American Heart Journal, August, S0002-8703(24)00205-9.
Multimodal Fusion Learning for Long QT Syndrome Pathogenic Genotypes in a Racially Diverse Population. Jiang, Joy, Ha My Thi Vy, Alexander Charney, Patricia Kovatch, Vivek Reddy, Pushkala Jayaraman, Ron Do, Rohan Khera, Sumeet Chugh, Deepak L. Bhatt, Akhil Vaid, Joshua Lampert, and Girish Nitin Nadkarni. NPJ Digital Medicine 7 (1): 226.
Sex-Specific Health-Related Quality of Life in Survivors of Cardiac Arrest. Ghassemi, Kaitlyn, Kyndaron Reinier, Sumeet S. Chugh, and Faye L. Norby. Resuscitation Plus 19 (September): 100736.
Computational Biomedicine
The Evolution of Computational Research in a Data-Centric World. Deshpande, Dhrithi, Karishma Chhugani, Tejasvene Ramesh, Matteo Pellegrini, Sagiv Shiffman, Malak S. Abedalthagafi, Saleh Alqahtani, Jimmie Ye, Xiaole Shirley Liu, Jeffrey T. Leek, Alvis Brazma, Roel A. Ophoff, Gauri Rao, Atul J. Butte, Jason H. Moore, Vsevolod Katritch, and Serghei Mangul. Cell 187 (17): 4449–57.
Competence Over Confidence: Uncovering Lower Self-Efficacy for Women Residents During Central Venous Catheterization Training. Tzamaras, Haroula, Elizabeth Sinz, Michael Yang, Phillip Ng, Jason Moore, and Scarlett Miller. BMC Medical Education 24 (1): 923.
Imaging
Potential Strength and Weakness of Artificial Intelligence Integration in Emergency Radiology: A Review of Diagnostic Utilizations and Applications in Patient Care Optimization. Fathi, Mobina, Reza Eshraghi, Shima Behzad, Arian Tavasol, Ashkan Bahrami, Armin Tafazolimoghadam, Vivek Bhatt, Delaram Ghadimi, and Ali Gholamrezanezhad. Emergency Radiology, August.
Medicine
Emerging Approaches for the Development of Artificial Islets. Li, Jingbo, Lingyu Sun, Feika Bian, Stephen J. Pandol, and Ling Li. Smart Medicine 3 (2): e20230042.
Celiac Disease Is Associated With Increased Risk of Deep Vein Thrombosis and Hypotensive Shock in Patients Admitted With Acute Pancreatitis. Abboud, Yazan, Vraj P. Shah, Yi Jiang, Navya Pendyala, and Kaveh Hajifathalian. JGH Open: An Open Access Journal of Gastroenterology and Hepatology 8 (8): e70017.
Telemedicine-Medical ‘Snack Community’-PHS Ecosystem: Insights into the Double-Edged Sword Role of Telemedicine in Clinical Practice and Medical Education During the COVID-19 Pandemic and Beyond. Feng, Dechao, Xu Shi, Jie Wang, Liying Zhang, Yuhan Xiao, Dengxiong Li, Ruicheng Wu, Wuran Wei, Akira Miyamoto, Koo Han Yoo, Xing Ye, Chi Zhang, and Ping Han. Exploration (Beijing, China) 4 (4): 20230111.
Evaluating No Fixation, Endoscopic Suture Fixation, and an Over-the-Scope Clip for Anchoring Fully Covered Self-Expanding Metal Stents in Benign Upper Gastrointestinal Conditions: A Comparative Multicenter International Study (With Video). Mehta, Amit, Ashraf Ashhab, Apurva Shrigiriwar, Redeat Assefa, Andrew Canakis, Michael Frohlinger, Christopher A. Bouvette, Gregus Matus, Paul Punkenhofer, Francesco Vito Mandarino, Francesco Azzolini, Jamil S. Samaan, Rashmi Advani, Shivani K. Desai, Bradley Confer, Vikas K. Sangwan, Jonh J. Pineda-Bonilla, David P. Lee, Kinnari Modi, Chiemeziem Eke, Moritz Schiemer, Elena Rondini, Werner Dolak, Emil Agarunov, Margaret Duku, Andrea Telese, Rishi Pawa, Swati Pawa, Natividad Zaragoza Velasco, Jad Farha, Rickisha Berrien-Lopez, Sherifatu Abu, Charlee K. McLean-Powell, Raymond E. Kim, Amir Rumman, Georg O. Spaun, Paolo G. Arcidiacono, Kenneth H. Park, Harshit S. Khara, David L. Diehl, Prashant Kedia, Armin Kuellmer, Raffaele Manta, Tamas A. Gonda, Vinay Sehgal, Rehan Haidry, and Mouen A. Khashab. Gastrointestinal Endoscopy, August, S0016-5107(24)03452-7.
NBS1 Lactylation and Damaged DNA Repair. Koeffler, H. Phillip. Cancer Letters, August, 217128.
Ancestral Diversity in Pharmacogenomics Affects Treatment for Hispanic/Latine Populations With Inflammatory Bowel Disease. Ioannou, S., A. Beecham, L. Gomez, R. Dauer, N. Khakoo, L. Pascual, M. Quintero, J. Lopez, J. S. Leavitt, N. Solis, M. Ortega, A. R. Deshpande, D. H. Kerman, S. Proksell, E. A. Torres, T. Haritunians, D. Li, M. T. Abreu, D. P. B. McGovern, J. L. McCauley, and O. M. Damas. Clinical Gastroenterology and Hepatology, August, S1542-3565(24)00766-3.
GIP Receptor Antagonism Eliminates Paradoxical Growth Hormone Secretion in Some Patients With Acromegaly. Jensen, Mette H., Lærke S. Gasbjerg, Kirsa Skov-Jeppesen, Jens C. B. Jacobsen, Steen S. Poulsen, Cuiqi Zhou, Ruta Jakubauskaite, Frantz R. Poulsen, Christian Bonde, Mahmoud Albarazi, Bo Halle, Charlotte B. Christiansen, Samra J. Sanni, Sarah Byberg, Bjørn Hoe, Jens J. Holst, Flemming Dela, Aase K. Rasmussen, Filip K. Knop, Mai C. Arlien-Søborg, Shlomo Melmed, Jens Otto L. Jørgensen, Marianne S. Andersen, Bolette Hartmann, Marianne C. Klose, Ulla Feldt-Rasmussen, Alexander H. Sparre-Ulrich, and Mette M. Rosenkilde. The Journal of Clinical Endocrinology and Metabolism, August, dgae583.
Prevalence of Oral Diseases in Patients Under Palliative Care: A Systematic Review and Meta-Analysis. Silva, Marina, Erison Santana Santos, Caique Mariano Pedroso, Joel B. Epstein, Alan Roger Santos-Silva, and Luiz Paulo Kowalski. Supportive Care in Cancer 32 (9): 607.
Genomic and Epigenomic Analysis of Plasma Cell-Free DNA Identifies Stemness Features Associated With Worse Survival in Lethal Prostate Cancer. Chauhan, Pradeep S., Irfan Alahi, Savar Sinha, Elisa M. Ledet, Ryan Mueller, Jessica Linford, Alexander L. Shiang, Jace Webster, Lilli Greiner, Breanna Yang, Gabris Ni, Ha X. Dang, Debanjan Saha, Ramandeep K. Babbra, Wenjia Feng, Peter K. Harris, Faridi Qaium, Dzifa Y. Duose, Alexander Sanchez-Espitia, Alexander D. Sherry, Ellen B. Jaeger, Patrick J. Miller, Sydney A. Caputo, Jacob J. Orme, Fabrice Lucien, Sean S. Park, Chad Tang, Russell K. Pachynski, Oliver Sartor, Christopher A. Maher, and Aadel A. Chaudhuri. Clinical Cancer Research, August.
Oncology Intensive Care Units: Distinguishing Features and Clinical Considerations. Davis, Hugh, Steve Tseng, and Weijia Chua. Journal of Intensive Care Medicine, August, 8850666241268857.
Effects of 8-h Time-Restricted Eating on Energy Intake, Dietary Composition and Quality in Adolescents With Obesity. Bakhsh, Jomanah A., My H. Vu, Sarah Jeanne Salvy, Michael I. Goran, and Alaina P. Vidmar. Pediatric Obesity, August, e13165.
Response to Mattiuzzi and Lippi. Liang, Jeff, Yi-Te Lee, and Ju Dong Yang. Clinical and Translational Gastroenterology, August.
Reply to Correspondence on Severity of Microvascular Invasion Does Matter in Hepatocellular Carcinoma Prognosis: Editorial on ‘Classification of Microvascular Invasion of Hepatocellular Carcinoma: Correlation With Prognosis and Magnetic Resonance Imaging.’ Attia, Abdelrahman M., Hasmik Adetyan, and Ju Dong Yang. Clinical and Molecular Hepatology, August.
Neurosurgery
Slow Ramping Emerges From Spontaneous Fluctuations in Spiking Neural Networks. Gavenas, Jake, Ueli Rutishauser, Aaron Schurger, and Uri Maoz. Nature Communications 15 (1): 7285.
OBGYN
Enhancing Patient Care in Low-Volume Practice Settings: The Crucial Role of Overseas Sub-Specialty Training. Levin, Gabriel, Yoav Brezinov, Yossi Tzur, Raanan Meyer, and Walter Gotlieb. International Journal of Gynecological Cancer, August, ijgc–2024–005936.
Correlation of Polycystic Ovarian Syndrome Phenotypes With Pregnancy and Neonatal Outcomes. Chan, Jessica L., Richard S. Legro, Esther Eisenberg, Margareta D. Pisarska, and Nanette Santoro. Obstetrics and Gynecology, August.
Racial Differences in the Incidence of Mental Health Illness Among Ovarian Cancer Patients: An Analysis of SEER-Medicare Data. Rahman, Fariha, Oyomoare L. Osazuwa-Peters, Clare Meernik, Kevin C. Ward, Margaret G. Kuliszewski, Bin Huang, Andrew Berchuck, Thomas Tucker, Maria Pisu, Margaret Liang, and Tomi F. Akinyemiju. SSM - Mental Health 6 (December): 100323.
Orthopaedics
Low Back Pain Caused by Traction Peripheral Neuropathy Due to Chronic Ankle Instability: Three Clinical Cases. Hagiwara, Yusuke, Yumiko Natsume, Tomomi Wagatsuma, Tetsuya Hasegawa, and Ryu Yoshida. Cureus 16 (7): e65405.
A Narrative Review on Recombinant Human Bone Morphogenetic Protein 2: Where Are We Now? Von Benecke, John P., Elisa Tarsitano, Laura-Marie A. Zimmermann, Kevin M. Shakesheff, William R. Walsh, and Hyun W. Bae. Cureus 16 (8): e67785.
Pathology and Laboratory Medicine
Race/Ethnicity Does Not Impact Surgical Management or Clinical Outcomes Among Insured Patients With Dermatofibrosarcoma Protuberans. Rosenthal, Amanda H., Geena Conde, Jing Zhang, Nima M. Gharavi, and Jeremy Man. Journal of the American Academy of Dermatology, August, S0190-9622(24)02552-0.
FAT1 Is a Target Antigen in a Subset of de Novo Allograft Membranous Nephropathy Associated With Antibody Mediated Rejection. Sethi, Sanjeev, Benjamin Madden, Marta Casal Moura, Samih H. Nasr, Mariam P. Alexander, Hanna Debiec, Nate Torrel, LouAnn Gross, Vivian Negron, Ulrich Specks, Fernando C. Fervenza, Mark Haas, Pierre Ronco, and Ibrahim Batal. Kidney International, August, S0085-2538(24)00569-6.
Pediatrics
Multiple Endocrine Defects in Adult-Onset Sprouty1/2/4 Triple Knockout Mice. Altés, Gisela, Anna Olomí, Aida Perramon-Güell, Sara Hernández, Anna Casanovas, Aurora Pérez, Juan Miguel Díaz-Tocados, José Manuel Valdivielso, Cristina Megino, Raúl Navaridas, Xavier Matias-Guiu, Ophir D. Klein, Joaquim Egea, Xavi Dolcet, Andrée Yeramian, and Mario Encinas. Scientific Reports 14 (1): 19479.
Psychiatry & Behavioral Neurosciences
How Are Anxiety and Fear Best Treated in Patients With Serious Illness and in Those Facing the End of Life? Trachsel, Manuel, Scott A. Irwin, and Harvey Max Chochinov. Therapeutische Umschau. Revue Therapeutique 81 (4): 115–21.
Radiation Oncology
Cardiac Substructure Radiation Dose and Associations With Tachyarrhythmia and Bradyarrhythmia After Lung Cancer Radiotherapy. Atkins, Katelyn M., Samuel C. Zhang, Christopher Kehayias, Christian Guthier, John He, Jordan O. Gasho, Mina Bakhtiar, Katrina D. Silos, David E. Kozono, Paul C. Zei, Anju Nohria, Andriana P. Nikolova, and Raymond H. Mak. JACC: CardioOncology 6 (4): 544–56.
Optimizing Cardiovascular Risk Prediction From CT Imaging at the Radiation Oncology Point of Care. Atkins, Katelyn M., and Andriana P. Nikolova. JACC: CardioOncology 6 (4): 541–43.
Surgery
Trapezius Fasciocutaneous Flap for Burn Reconstruction. Nasrollahi, Tasha, Michela Borrelli, Katrin Salehi, Martin L. Hopp, and David Alessi. Ear, Nose, & Throat Journal 103 (8): 487–89.
Beyond American College of Surgeons Verification: Quality Metrics Associated With High Performance at Level I and II Trauma Centers. Cho, Nam Yong, Jeff Choi, Saad Mallick, Galinos Barmparas, David Machado-Aranda, Areti Tillou, Daniel Margulies, Peyman Benharash, and Academic Trauma Research Consortium (ATRIUM). Journal of the American College of Surgeons, August.
24-Hour Telemetry Monitoring May Not Be Necessary for Patients With an Isolated Sternal Fracture and Minor ECG Abnormalities or Troponin Elevation: A Southern California Multicenter Study. Al-Khouja, Fares, Areg Grigorian, Brent Emigh, Morgan Schellenberg, Graal Diaz, Thomas K. Duncan, Rahul Tuli, Raul Coimbra, Kacy Gilbert-Gard, Arianne Johnson, Makenna Marty, Mallory Jebbia, Amal K. Obaid-Schmid, Nicole Fierro, Eric Ley, Dunya Bayat, Walter Biffl, Shayan Ebrahimian, Areti Tillou M, Erica Tay-Lasso, Claudia Alvarez, and Jeffry Nahmias. The American Surgeon, August, 31348241278904.
When a Lung Nodule Program Becomes Self-Aware. Brownlee, Andrew R. The Annals of Thoracic Surgery 118 (3): 718–19.
Repair of a Large Volume Nasal Tip Mohs Defect. Nadeem, Wasiq, Jordan K. Simmons, Nima Gharavi, and Matthew K. Lee. Dermatologic Surgery, August.
Urology
Genomic and Epigenomic Analysis of Plasma Cell-Free DNA Identifies Stemness Features Associated With Worse Survival in Lethal Prostate Cancer. Chauhan, Pradeep S., Irfan Alahi, Savar Sinha, Elisa M. Ledet, Ryan Mueller, Jessica Linford, Alexander L. Shiang, Jace Webster, Lilli Greiner, Breanna Yang, Gabris Ni, Ha X. Dang, Debanjan Saha, Ramandeep K. Babbra, Wenjia Feng, Peter K. Harris, Faridi Qaium, Dzifa Y. Duose, Alexander Sanchez-Espitia, Alexander D. Sherry, Ellen B. Jaeger, Patrick J. Miller, Sydney A. Caputo, Jacob J. Orme, Fabrice Lucien, Sean S. Park, Chad Tang, Russell K. Pachynski, Oliver Sartor, Christopher A. Maher, and Aadel A. Chaudhuri. Clinical Cancer Research, August.