Faculty Publications Sept. 3-10

This week’s edition of Faculty Publications includes Cedars-Sinai studies that were published Sept. 3-10. If you have a published paper from this period that does not appear on this list, please contact Sue Marone.

Cedars-Sinai in the News

‘The Pitt’ To Be Honored by Cedars-Sinai | Variety
Peter L. Slavin, MD 

Probing the Proteome at Cellular Scale | Nature
Jennifer Van Eyk, PhD

8 Weird Signs You’re Having a Stroke | Everyday Health
Alexis Simpkins, MD, PhD

Female Cardiologists Swear by These Easy Heart Health Habits | MSN.com
C. Noel Bairey Merz, MD

Long-Term Trial Supports Selective Use of Extended Pelvic Lymph Node Dissection in High-Grade Prostate Cancer | The ASCO Post
Adam B. Weiner, MD

Declining Flu Vaccination Rates Could Increase Severity of 2026 Influenza Season | Respiratory Therapy
Michael Ben-Aderet, MD

Faculty Publications

Biomedical Sciences

Epicardial Adipose Tissue Attenuation and Persistent Left Ventricular Dysfunction in Heart Failure With Reduced Ejection Fraction (RECOVER-EAT). Khanna, Shaun, Nicholas McLellan, Sheran Vasanthakumar, Cheng Hwee Soh, Aditya Bhat, Andrew Lin, Damini Dey, Sriram Rao, Stephen J. Nicholls, Clare Arnott, and Nitesh Nerlekar. Journal of Cardiac Failure, September, S1071-9164(26)00515-4.

Cardiology

Emerging Longer-Term Evidence on Transcatheter Aortic Valve Implantation for Severe Aortic Stenosis in Low-Risk Patients: A Call for Caution. Sousa Uva, Miguel, Milan Milojevic, Mateo Marin-Cuartas, Sanjay Kaul, Raffaele De Caterina, Rita Redberg, Samuel Heuts, Torsten Doenst, Victor Dayan, Matthias Siepe, Vinay Badhwar, Volkmar Falk, Michael A. Borger, Patrick O. Myers, and Rafael Sadaba. The Annals of Thoracic Surgery, September, S0003-4975(26)00894-5.

Heart Transplantation in 2076: Precision, Prevention, and Regeneration. Stern, Lily K., Kelly Perkins, and Jon A. Kobashigawa. Journal of Cardiac Failure 32 (9): 1652–55.

Maternal Hyperoxygenation for Prenatal Risk Stratification of Pulmonary Venous Obstruction in Total Anomalous Pulmonary Venous Return. Mathevosian, Michelle, Shuo Wang, Arpine Davtyan, Jon Detterich, Jodie Votava-Smith, and Jay Pruetz. Pediatric Cardiology, September.

Noncoding RNA TY1 Reverses Fibrosis in Systemic Sclerosis by Attenuating the cGAS/STING Pathway. Jones, Xaviar M., Salwa Soussi, Alessandra Ciullo, Kara Tsi, Weixin Liu, Liang Li, Mario Fournier, Thassio Mesquita, Alberto M. Marchevsky, Nunzio Bottini, Francesco Boin, Ahmed Ge Ibrahim, and Eduardo Marbán. JCI Insight 11 (17): e197716.

Transcatheter vs Surgical Replacement of Degenerated Bioprosthetic Aortic Valve: A Meta-Analysis of Propensity-Score-Matched Studies. Ebrahimi, Pouya, Maryam Taheri, Mehrdad Mahalleh, Hamidreza Soleimani, Homa Taheri, Ali Moradi, Babak Sattartabar, Morvarid Taebi, Iman Bhia, Reza Pirdehghan, Mohsen Anafje, Mohamad Alkhouli, Masih Tajdini, Amr Mohsen, Islam Elgendy, Robert J. Siegel, Mohammad Hossein Mandegar, and Kaveh Hosseini. Heart, Lung & Circulation, September, S1443-9506(26)00192-7.

Computational Biomedicine

A Framework for Cognitive Personality Priors in Agentic AI: The Role of Personas in Autonomous Team Science. Nawaz, Asma J., Jake R. Patock, Itzel Valencia, Binglan Li, Jacob S. Berkowitz, Stefany Coxe, Itai Danovitch, Nicholas P. Tatonetti, and Jason H. Moore. BioData Mining 19 (1): 75.

Discovering Repurposable Drugs for Alzheimer’s Disease and Related Dementias: Target Trial Emulation Using Decentralised Real-World Data. Wu, Qiong, Lu Li, Yuqing Lei, Ting Zhou, Huilin Tang, Bingyu Zhang, Yiwen Lu, Maxwell Salvatore, Dazheng Zhang, Jiayi Tong, Tingyin Wang, Siqi Chen, Haoyang Li, Zhenxing Xu, Yu Huang, Yu Hu, Na Hong, Yujia Zhou, Fongci Lin, Kyra S. O’Brien, Yong Chen, Ruowang Li, Hua Xu, Fei Wang, Jiang Bian, David A. Wolk, and Yong Chen. EBioMedicine 132 (September): 106466.

Secondary Pharmacology Targets for Pediatric Developmental Safety Assessment of New Drugs: Clinical Pharmacology Considerations. Burckart, Gilbert J., Sherbet Samuels, Susan M. Abdel-Rahman, Gelareh Abulwerdi, Elimika Fletcher, Mohamed A. Mohamoud, Apoorva Srinivasan, Nicholas Tatonetti, and Rebecca Racz. Clinical Pharmacology and Therapeutics, September.

Nonparametric D-Test for Homogeneity With Flexible Null and Alternative Hypotheses. Kabir, Shaowli, Derek S. Young, Javier A. Neyra, and Richard J. Charnigo. Statistical Methods & Applications, August.

Privacy-Preserving Multi-Agent Systems for Human-Centred Inclusive Healthcare AI. Mahmud, Mufti, Noushath Shaffi, M Shamim Kaiser, M Arifur Rahman, M Mostafizur Rahman, Vimbi Viswan, Tamanna Sharmeen, Sweta Bhattacharya, Neelu Jyoti Ahuja, Ayse Ulgen, Imran Khan Niazi, Kanad Ray, Amir Hussain, David J Brown, and Jason H. Moore. AI Magazine 47 (3): e70087.

Imaging

Imaging Intraosseous Hemangiomas: Typical and Atypical Features Across Modalities. Bonzell, Casey, Jonathan Lee, Michelle R. Santoso, Michelle Chen, Adam Miller, and Ali Gholamrezanezhad. Seminars in Nuclear Medicine, September, S0001-2998(26)00163-7.

Medicine

Advances and Challenges to Colonoscopy Quality. Khan, Haidar, Ramya Vasireddy, Mahnoor Khan, and Rashmi Advani. Gastrointestinal Endoscopy Clinics of North America 36 (4): 703–18.

Discontinuation of Statins by Patient and Physician Sex: An Observational Study. Watanabe, Atsuyuki, Yoshihisa Miyamoto, Hiroki A. Ueyama, Hiroshi Gotanda, Leandro Slipczuk, Kosuke Inoue, Eric Secemsky, Roger Laham, Deepak L. Bhatt, Yusuke Tsugawa, and Toshiki Kuno. Journal of Cardiology 88 (2): 116–22.

Do Multi-Omics Approaches Improve the Diagnosis of Microbial Overgrowth Syndromes? Freitas Germano, Juliana de, Gabriela Leite, and Mark Pimentel. Current Gastroenterology Reports 28 (1): 29.

Esophageal Epidermoid Metaplasia in a Patient With Dysphagia and Severe Esophageal Stenosis. Gornick, Dana J., Michael Kozak, and Amrit K. Kamboj. Gastrointestinal Endoscopy, September, S0016-5107(26)07023-9.

Fludarabine and Total Body Irradiation 800 cGy or 1125 cGy for Allogeneic Stem Cell Transplant Using Graft Versus Host Disease Prophylaxis With Post-Transplant Cyclophosphamide and Tacrolimus, Without Mycophenolate Mofetil (OmitMMF Trial). Paquette, Ronald, Haein Kim, Vinicius F. Calsavara, Noah Merin, John Chute, Justin Darrah, Hannah Lee, David Oveisi, Josh Sasine, Robert Vescio, Vanshika Chauhan, Joseph Lownik, and Akil Merchant. Transplantation and Cellular Therapy, September, S2666-6367(26)00715-3.

Longitudinal Repeated Protein Measurements in a Multiethnic Cohort Identify Novel Diabetes Biomarkers That Reveal Unique Disease Pathways. Chen, Zsu-Zsu, Michael Y. Mi, Jacob Barber, Gaurav Tiwari, Charleen D. Adams, Shuliang Deng, Christopher Y. Shin, Laurie Farrell, Prashant Rao, Daniel E. Cruz, James G. Wilson, Magdalena Sevilla-Gonzalez, Yii-Der Ida Chen, Xiuqing Guo, Mark O. Goodarzi, Kent D. Taylor, Usman A. Tahir, Stephen S. Rich, Alexis C. Wood, Robert E. Gerszten, and Jerome I. Rotter. Diabetes, September, db260148.

New Developments in the Treatment of Hepatitis B Virus Infection. Sandhu, Sunny, Paul Martin, and Ira M. Jacobson. Gastroenterology & Hepatology 22 (7): 350–61.

Operationalizing Patient Flow in High-Complexity Service Lines: A Health System Perspective Using Oncology Care. Figlin, Robert, Kate O’Shaughnessy, Setu Shah, Chad Giese, Jamie Bachman, Matthew Bednar, Jennifer Scalise, and Aleksandar Zafirovski. Frontiers in Health Services 6: 1859412.

Outcomes of Surgical Aortic Valve Replacement With Coronary Artery Bypass Grafting Versus Transcatheter Aortic Valve Replacement With Percutaneous Coronary Intervention. Dulal, Dharmindra, Ahmed Maraey, Vahid Yazdi, Juan Carlo Avalon, Cezar Iliescu, Mehmet Cilingiroglu, Konstantinos Marmagkiolis, and Konstantinos Dean Boudoulas. Cardiovascular Revascularization Medicine: Including Molecular Interventions, September, S1553-8389(26)00378-7.

Patients’ Real-World Experiences With Pharmacologic Therapies for Irritable Bowel Syndrome With Constipation: A Mixed-Methods Analysis and Classification of Social Media and E-Forum Posts. Khalil, Carine, Karisma K. Suchak, Ivan Flores Amaro, Zoe Krut, Jordy O’Campo, Karen O’Connor, Allistair Clark, David P. Rosenbaum, Sharon Funk, Graciela Gonzalez-Hernandez, Brennan M. R. Spiegel, and Christopher V. Almario. Neurogastroenterology and Motility 38 (9): e70432.

PET, Proteomics, and Immunophenotyping of Arterial Inflammation and Checkpoint Inhibition. Rankin, Stephen, Neil MacRitchie, Moustafa I. Morsy, Alastair J. Gemmell, Alasdair Henderson, Claire Glen, Katriona Brooksbank, Piotr Slomka, Kieran F. Docherty, Marc R. Dweck, John McClure, Elaine Butler, Paul Welsh, Sarah Slater, Manreet Randhawa, Ashita Waterston, Kun Yang, Ahmad Alsaeed, Pavlina Spiliopoulou, Robert Jones, Greg Naylor, Thomas R. Jeffry Evans, Balaji Venugopal, Alexander Small, Dave Colville, Mark C. Petrie, Pasquale Maffia, and Ninian N. Lang. JAMA Cardiology, September.

Pre-Treatment T Cell Features and Immune-Milieu Characteristics Shape Treatment-Induced Exhaustion and Resistance to Blinatumomab in B-Cell Acute Lymphoblastic Leukemia. Corrado, Francesco, Viktoria Blumenberg, Maryam Kazerani, Jan Wulf, Tobias Straub, Nora Philipp, Daniel Nixdorf, Amelie Muth, Giulia Rappa, Agnese Petrera, Michaela Scheurer, Chang-Feng Chu, Giulia Magno, Christina E. Zielinski, Michael von Bergwelt-Baildon, Marion Subklewe, and Veit Bücklein. Frontiers in Immunology 17: 1895742.

Reddit for Redness: A Cross-Sectional Analysis of the r/Rosacea Forum. Kotlyar, Joshua, Robert Adler, Ugwumsinachi Nwaubani, William Mark Richardson, and Justin W. Marson. Journal of Drugs in Dermatology: JDD 25 (8): e71–72.

The Evolution of Immunotherapy Revolution in Lung Cancer: A 20-Year Perspective. Waissengrin, Barliz, Marco Tagliamento, Kamya Sankar, and Karen L. Reckamp. Journal of Thoracic Oncology, 21 (9): 103957.

UBE2N Deficiency Contributes to MASH Development via P62-Regulated Mitophagy and PANoptosis. Wang, Feng, Jin Lee, Jeong-Su Park, Meizhou Huang, Hwan Ma, Guoyan Sui, Zixiong Zhou, Michitaka Matsuda, So Yeon Kim, Takashi Tsuchiya, Xuefeng Wu, Haram Lee, Soohwan Oh, Hanseul Park, Key-Hwan Lim, Chun-Woong Park, Sang-Bae Han, Jin Tae Hong, Michael Karin, Yoon Seok Roh, and Ekihiro Seki. Nature Metabolism, September.

Young Women With Pancreatic Cancer: A High-Risk Group for Demoralization. Levi, Abrahm, Aryan Nasr, Yujie Cui, Anser A. Abbas, Tara T. Arouchian, Andrew L. Coveler, Tracey L. Pierce, Brian T. Anderson, Eric Collisson, John Davelaar, Simon K. Lo, Srinivas Gaddam, Jun Gong, Arsen Osipov, and Andrew E. Hendifar. Psycho-Oncology 35 (9): e70601.

Neurology

Imaging Characterization and Vascular Topography of Vertebral Body Infarctions in Spinal Cord Stroke. Barreras, Paula, David Acero-Garces, Lydia Gregg, Hao Wen Chen, Karissa Arthur, Philippe Gailloud, Doris D. M. Lin, and Carlos A. Pardo. European Journal of Radiology 205 (August): 113182.

Orthopaedics and Sports Medicine

Clinical Work-up, Diagnostic Imaging, and Radiographic Classification Systems for Osteochondral Lesions of the Talus: Proceedings of the International Consensus Meetings on Cartilage Repair of the Ankle. Tham, Alexander, Jared Rubin, James J. Butler, Paloma Gauthier, John G. Kennedy, Samuel B. Adams, Carol L. Andrews, Chayanin Angthong, Jorge P. Batista, Onno L. Baur, Steven Bayer, Christoph Becher, Zijun Zhang, et al. Foot & Ankle Specialist, September, 19386400261478702.

Overcoming Space and System Limitations: A Novel Lamina Spreader Technique for Optimal Reduction via External Fixation. Meltzer, Jourdan H., and Carol Lin. Foot & Ankle Orthopaedics 11 (3): 24730114261481810.

Survival Prognostication in Spinal Metastasis: From Clinical Intuition to Data-Driven Decision Making. Striano, Brendan M., Matthew T. Kim, Joseph H. Schwab, Andrew J. Schoenfeld, and Daniel G. Tobert. Spine, September.

Transverse Tibial Transport for Limb Salvage in Ischemic Lower Extremity Disease: Technique, Mechanisms, and Clinical Outcomes-A Systematic Review. Raszka, Samuel, Max Michalski, and Charles Moon. The Orthopedic Clinics of North America 57 (4): 339–48.

Pathology and Laboratory Medicine

Comparative Efficacy of Oral Antibiotics against Intracellular Populations of Uropathogenic Escherichia Coli and Bladder Cell Inflammatory Response. Kalu, Michelle, Peter Jorth, and Annie Wong-Beringer. European Journal of Clinical Microbiology & Infectious Diseases, September.

Digitalization of Medical and Healthcare Education in a Low- and Middle-Income Country: A Mixed-Method Case Study of Institutional Transformation at Yerevan State Medical University. Sargsyan, Karine, Tamara Sarkisian, Hasmik Tumanyan, Sergey Sargsyan, Khachatur Margaryan, Konstantin Yenkoyan, Larisa Avetisyan, Garnik Avetisyan, and Armen Muradyan. Frontiers in Digital Health 8: 1901577.

Human Y Chromosome Pan-Organ Mapping Reveals Progressive Mosaic Loss From Normal to Cancer. Gertych, Arkadiusz, Huihui Ye, Xingyu Chen, Eric Vail, V. Krishnan Ramanujan, Lauren Brady, Lawrence D. True, Peter S. Nelson, Peter R. Carroll, and Dan Theodorescu. JCI Insight 11 (17): e201996.

Pediatrics

Accelerated Desensitization Enables HLA-Incompatible Deceased Donor Kidney Transplant in a Highly Sensitized Pediatric Recipient. Pande, Nivedita, Muneera Alabdulqader, Marie-Michèle Gaudreault-Tremblay, Myriam Carlos, Bethany J. Foster, Jean Tchervenkov, Claude Daniel, Dechu Puliyanda, Indra R. Gupta, and Mallory L. Downie. Human Immunology 87 (11): 112065.

Building and Regenerating Intestines by Manipulating Intestinal Stem Cells. Kuo, Calvin J., Sarah Blutt, Mark Donowitz, Mary K. Estes, Chandan Guha, Ophir D. Klein, Linheng Li, Joyce C. Niland, António J. M. Santos, Ramesh A. Shivdasani, Jason R. Spence, Carol J. Swanson, Timothy C. Wang, Kelley S. Yan, Nicholas C. Zachos, and Michael A. Helmrath. Nature Reviews. Gastroenterology & Hepatology, September.

Hospitalization Costs of Kidney Transplantation Associated With Induction Therapy Among Pediatric Kidney Transplant Recipients: A North American Pediatric Renal Trials and Collaborative Studies and Pediatric Health Information System Collaborative Study. Rodig, Nancy M., Daniella Levy Erez, Helen P. Pizzo, Troy Richardson, and Michael J. Somers. Pediatric Transplantation 30 (9): e70441.

Radiation Oncology

Making Scents Out of the Best ‘Smell’ Tests in the Age of Clinical Artificial Intelligence. Chetty, Indrin J., and Sue S. Yom. International Journal of Radiation Oncology, Biology, Physics 126 (2): 289.

Surgery

Aberrant Left Vertebral and Aberrant Right Subclavian Arteries in Blunt Thoracic Aortic Injury Patients: A Multicenter Registry Study. Rodriguez, Sean, Chase Caswell, Benjamin W. Starnes, Elina Quiroga, Joseph DuBose, Charles C. Miller, David McGreevy, Ali Azizzadeh, Peter J. Rossi, and Aortic Trauma Foundation Collaborators. Annals of Vascular Surgery, September, S0890-5096(26)00641-2.

Actual Five-Year Survival After Neoadjuvant Therapy and Resection for Localized Pancreatic Ductal Adenocarcinoma. De Stefano, Federico, Giulio Belfiori, Nathaniel F. Wu, Jill N. Allen, Laura Cerri Crn, Jeffrey W. Clark, Paolo Giorgio Arcidiacono, Cristina Ferrone, Theodore S. Hong, Domenico Tamburrino, Stefano Partelli, Motaz Qadan, Michele Reni, David P. Ryan, Marco Schiavo Lena, Gabriele Capurso, Colin D. Weekes, Jennifer Y. Wo, Keith D. Lillemoe, Stefano Crippa, Massimo Falconi, and Carlos Fernández-Del Castillo. Annals of Surgery, September.

Complete Disruption of gD Binding to HVEM Alters Virus Replication and Host Receptor Homeostasis. Arya, Deepak, Kati Tormanen, Jay J. Oh, Shaohui Wang, and Homayon Ghiasi. PLoS Pathogens 22 (9): e1014566.

Efficacy and Safety of Local Tranexamic Acid in Rhytidectomy: A Systematic Review and Meta-Analysis. Mokhtar, Jonathan, Marwa Hadi, Lucas Kreutz-Rodrigues, Kevin Sadati, Krishna S. Vyas, Curtis L. Cetrulo, and Alexandre G. Lellouch. Plastic and Reconstructive Surgery. Global Open 14 (9): e8083.

Epigenetic Profiling Reveals M1 Macrophages as the Primary Drivers of Trained Immunity in HSV-1 Latently Infected Mice. Jaggi, Ujjaldeep, Shaohui Wang, and Homayon Ghiasi. PLoS Pathogens 22 (9): e1014598.

High-Frequency High-Intensity Focused Ultrasound (HF-HIFU) for Ablation of Benign, Premalignant, and Malignant Cutaneous Lesions: A Systematic Review. Aguglia, Raffaele, Tobias Niederegger, Murtaja Satea, Leonard Knoedler, Moshé Assouline, Curtis L. Cetrulo, Michael Atlan, and Alexandre G. Lellouch. European Journal of Dermatology: EJD 36 (4): 312–23.

Hospital-Level Determinants of Mortality After Pancreas Surgery: A Global Infrastructure Analysis. Hidalgo Salinas, Camila, Pascale Tinguely, Dimitri A. Raptis, Sterre van Herwijnen, Ammar A. Javed, Rafael Perera, Cristina R. Ferrone, Christopher L. Wolfgang, Giuseppe K. Fusai, and PancreasGroup.org Collaborative. Annals of Surgery, September.

Hybrid Robotic TransVersus Abdominis Release (hrTAR) for Complex Ventral Hernias: A Systematic Review and Preliminary Synthesis. Satea, Murtaja, Luis Osvaldo Suárez Carreón, José Maria Zepeda Torres, Mor Rittblat, Morgan L. Hennessy, Haïzam Oubari, Alexandre G. Lellouch, and Rodolfo J. Oviedo. Journal of Robotic Surgery 20 (1): 957.

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