Faculty Publications Nov. 5-12
A Comprehensive Digest of Research Publications From Cedars-Sinai Investigators and a Sampling of Recent Media Coverage Featuring Faculty
This week’s edition of Faculty Publications includes Cedars-Sinai studies that were published Nov. 5-12. If you have a published paper from this period that does not appear on this list, please contact Sue Marone.
Cedars-Sinai in the News
Can Prehabilitation Improve Surgical Outcomes for Patients With IBD? | OncoDaily
Peter L. Slavin, MD
Why Are Fewer Black Americans Getting GLP-1s? | Vox
Amanda Velazquez, MD
AHA Scientific Sessions 2026: Key Trends Include AI, Negative Trial Results and Multidisciplinary Care | Cardiovascular Business
Joanna Chikwe, MD
How Nocturnal Hypertension Can Have a Sneaky Impact on Your Heart | The Washington Post
Joseph Ebinger, MD
The 5 Medications Most Likely To Cause Bone Thinning | The Washington Post
Natasha Trentacosta, MD
Uveal Melanoma: Dual T Cell Drugs Hit 70% Two-Year Survival Where Checkpoint Drugs Failed | Tech Times
Omid Hamid, MD
'A Bit of a New Era': Navigating Options in HR-Positive Metastatic Breast Cancer | Oncology News Central/Peer-Spectives Podcast
Robert Figlin, MD
Your Joint Pain Could Worsen in Cooler Weather. Here’s What To Do About It | The Independent
Mariko Ishimori, MD
Building the Modern PCa Biomarker Testing Framework | DocWire News
Stephen Freedland, MD
Drink 3 Cups of Coffee a Day? A Study Links the Habit to Lower Risks of 3 Serious Health Problems | Inc.
Hyunseok Kim, MD, MPH, PhD
Faculty Publications
Biomedical Sciences
A RARγ-SMARCA5 Chromatin-Remodeling Axis Stabilizes AR Luminal Programs and Opposes Lineage Plasticity in Prostate Cancer. Wani, Sajad A., Shahid Hussain, Khalid B. Mir, Jaimie S. Gray, Debasis Nayak, Hancong Tang, Lillian M. Perez, Mark D. Long, Manjunath Siddappa, Eva Corey, Peter S. Nelson, Christopher J. McCabe, Lara E. Sucheston-Campbell, Michael R. Freeman, and Moray J. Campbell. Nucleic Acids Research 54 (21): gkag1138.
CT-Based Deep Learning Assessment of Aortic Valve Fibrosis and Calcification: Development and Multicenter External Validation Against Experts, Histology, and Outcomes. Grodecki, Kajetan, Nipun Manral, Jacek Kwiecinski, Joel Lenell, Sebastien Cadet, Tara Zuhair Kassem, Jolien Geers, Caroline Park, Emily Xing, Guadalupe Flores Tomasino, Anna Olasinska-Wisniewska, Rafal Wolny, Maciej Dabrowski, Marcin Protasiewicz, Zbigniew Chmielak, Wojciech Wojakowski, Julia Niemierko, Jadwiga Fijalkowska, Bartosz Rymuza, Radoslaw Parma, Piotr Scislo, Marcin Grabowski, Dariusz Jagielak, Andrzej Walczak, Adrianna Hajder, Matylda Grodecka, Radoslaw Gocol, Tomasz Urbanowicz, Bartłomiej Perek, Marek Jemielity, Krzysztof Reczuch, Marek Grygier, Philipp Ruile, Simon Schoechlin, Hesham Elzomor, Michelle C. Williams, Marc R. Dweck, Daniel S. Berman, David E. Newby, Janusz Kochman, Hasan Jilaihawi, Raj Makkar, Piotr J. Slomka, Adam Witkowski, Zenon Huczek, and Damini Dey. JACC. Cardiovascular Imaging, November, S1936-878X(26)00506-1.
Cardiac Surgery
Multiomics Integration Reveals a Skeletal Muscle Metabolic Myopathy in Cardiometabolic HFpEF. Allerton, Timothy D., Daniel Arabie, Kade Malone, Abhishek Pandit, Mahmoud H. Elbatreek, Zhen Li, Robert C. Noland, Jake Doiron, Mike Kinter, Brooke Loveland, Pravalika Javvadi, Kirti Agrawal, Manas R. Gartia, Praveen Kumar Guttula, Traci T. Goodchild, Sanjiv J. Shah, Sujoy Ghosh, and David J. Lefer. Circulation. Heart Failure, November, e014126.
Robotic Mitral Valve Surgery in 2026: Outcomes, Adoption, the Learning Curve, and Real-World Evidence. Sun, Calvin, Maria Theresa Servito, Johnny Wang, and Derrick Y. Tam. Current Opinion in Cardiology, November.
Cardiology
Artificial Intelligence Detects Cardiac Amyloidosis Before Clinical Diagnosis. Yuan, Victoria, Saisanjana Kalagara, Hirotaka Ieki, Ankeet S. Bhatt, Andrew P. Ambrosy, Aly Elezaby, Lily K. Stern, Paul P. Cheng, and David Ouyang. Journal of Cardiac Failure 32 (11): 2025–28.
Association Between the Neutrophil:Lymphocyte Ratio After Hospitalization for Sepsis and Long-Term Outcomes: A Population-Based Cohort Study. Lawler, Patrick R., Olivia Haldenby, Alice Chong, Manu Shankar-Hari, Peter C. Austin, Lucas L. Marinho, Leah Kosyakovsky, Federico Angriman, Alisa M. Higgins, Gabriele Lileikyte, Lucas C. Godoy, Guillaume Butler-Laporte, Damon C. Scales, Fernando G. Zampieri, Edy Y. Kim, Rebecca M. Baron, David E. Leaf, Cristina T. Pop, Michael C. Sklar, Jacob C. Jentzer, Michael E. Farkouh, Sylvain A. Lother, John C. Marshall, Ryan Zarychanski, James A. Russell, Derek C. Angus, and Dennis T. Ko. Critical Care Medicine, November.
Automated Deep Learning Pipeline for Characterizing Left Ventricular Diastolic Function. Yuan, Victoria, Yuki Sahashi, Hirotaka Ieki, Teodora Szasz, Miloš Vukadinovic, Christina Binder, Karima Addetia, Martin Gruca, Konrad Pieszko, Andrew P. Ambrosy, Jeremy A. Slivnick, Paul P. Cheng, Susan Cheng, and David Ouyang. Journal of Cardiac Failure 32 (11): 1878–88.
Development of a Quantitative Contrast CT-Based TAVR-Risk Score to Reliably Predict Deformation in Bicuspid Aortic Valves. Suruga, Kazuki, Vivek Patel, Hasan Jilaihawi, Hidemasa Shitan, Tej Sheth, Yuchao Guo, Takashi Nagasaka, Daniel Ng, Tarun Chakravarty, Wen Cheng, Yuito Okada, Aakriti Gupta, Mamoo Nakamura, and Raj R. Makkar. JACC. Cardiovascular Interventions 19 (21): 2922–36.
Prevalence and Consequences of Guideline-Directed Indications for Aortic Valve Replacement in the EARLY TAVR Trial. Madhavan, Mahesh V., Allan Schwartz, Brian R. Lindman, Philippe Pibarot, David J. Cohen, J. Bradley Oldemeyer, Vasilis Babaliaros, William F. Fearon, David Daniels, Adnan Chhatriwalla, Clifford J. Kavinsky, Pinak Shah, Molly Szerlip, Thom Dahle, Kashish Goel, William O’Neill, Raj Makkar, Charles Davidson, Tej Sheth, Paul Sorajja, James DeVries, Jeffrey Southard, Jeremiah P. Depta, Andrei Pop, Rebbecca T. Hahn, Yanglu Zhao, Martin B. Leon, Philippe Genereux, and EARLY TAVR Trial Executive Committee and Study Investigators. JACC. Cardiovascular Interventions 19 (21): 2876–88.
When Leaflet Thickening Becomes More Than an Imaging Finding. Gupta, Aakriti, Hasan Jilaihawi, and Raj R. Makkar. Journal of the American College of Cardiology 88 (19): 2198–2201.
Computational Biomedicine
Blood-Based RNA Biomarker for the Early Detection of Ovarian Cancer. Wilhelm, Jochen, Amit Kumar, Hitesh Vasiyani, Narsimha Mamidi, Zhaoyu Sun, Aenya Gogna, Praveen Bhoopathi, Keshav C. Gogna, Chelsea Salyer, Amy Lu, Kranthi Kumar Chougoni, Ava N. Gardner, Esha Madan, et al. Nature Medicine, November.
xTracer: Integrating Chromatogram and Mobilogram Correlations for Untargeted Peptide Identification in SLIM-Based PAMAF Data. Song, Jian, Liulin Deng, Lauren Royer, Bennett Kalafut, Daniel DeBord, and Jesse G. Meyer. Analytical Chemistry 98 (44): 30080–90.
Medicine
Exploring the Evolving Role of US Hospital Chaplains During COVID-19 Through a Job Demands-Resource Theoretical Lens. Kim, Linda Y., Adrienne Martinez-Hollingsworth, Sarah Low, Jason Weiner, Christina Shu, Bernice Coleman, and Lucia Florindez. Journal of Religion and Health, November.
Glucagon-like Peptide-1 Receptor Agonists and Thyroid Cancer: Review of Preclinical and Human Data. Braunstein, Elsa W., and Glenn D. Braunstein. Endocrine Reviews, November, bnag044.
Hyperaldosteronism Remission After Extended Aldosterone Synthase Inhibition. Brown, Morris J., Adina F. Turcu, Ramin Sam, Lawrence S. Kirschner, Oksana Hamidi, Aysegul Eren, Anat Ben-Shlomo, Wenyu Huang, Irina Bancos, Amir H. Hamrahian, and Mason W. Freeman. The New England Journal of Medicine, November.
Irritable Bowel Syndrome in the Community: A Cross-Sectional Study Looking at Patient Experiences and Challenges With the Low FODMAP Diet. Fehlman, Jared, Westley Peng, Christian Pfenning, Hayley McCorkle, Judy W. Nee, William D. Chey, Ceciel Rooker, Sarah Ballou, Allen A. Lee, and Prashant Singh. Frontiers in Gastroenterology 5: 1930300.
Peripheral T- and B-Cell Immune Signatures Associated With Response to Vedolizumab in Ulcerative Colitis. Horitani, Shunsuke, Anna Horitani, Christopher J. Tyler, Makoto Naganuma, Peter B. Ernst, Davey Smith, Derek R. Patel, Brian Behm, Andres Yarur, and Jesús Rivera-Nieves. Inflammatory Bowel Diseases, November, izag242.
Real-World LAG3 Expression as A Biomarker in Advanced Melanoma: Implications for Treatment Selection. Mehmi, Inderjit, Jonathan E. Cohen, Kathryn Bollin, Siwen Hu-Lieskovan, Adam Dugan, Binyam Yilma, Stamatina Fragkogianni, Unnati Jariwala, Jacob Mercer, and Omid Hamid. The Oncologist, November, oyag441.
Second Primary Cancer Risk by Race and Ethnogeographic Region Among Asian American and Pacific Islander Breast Cancer Survivors in the United States. Ramin, Cody, Jessica P. Li, Lan Zhang, Kekoa Taparra, Lene H. S. Veiga, Amy Berrington de Gonzalez, Gretchen L. Gierach, Jaimie Z. Shing, and Jacqueline B. Vo. Cancer Medicine 15 (11): e72424.
Suppression of Epithelial Proliferation and Tumorigenesis by IgA. Donaldson, Gregory P., Gabriella Lima Dos Reis, Marwa Saad, Christopher Wichmann, Izabela Mamede, Guo Chen, Caroline E. Harrer, Nicole L. DelGaudio, Dayu Zhang, Begüm Aydin, Tiago B. R. Castro, Sergei I. Grivennikov, Bernardo S. Reis, Elise G. Liu, Stephanie C. Eisenbarth, Kivanç Birsoy, Sohail F. Tavazoie, Beth M. Stadtmueller, Gabriel D. Victora, and Daniel Mucida. Nature, November.
The Application of an Artificial Intelligence-Enhanced Virtual Reality Cognitive Behavioral Therapy Tool Is Feasible and Acceptable in Patients With Inflammatory Bowel Disease: A Multicenter Mixed Methods Pilot Study. George, Alvin T., Alexandra R. McDermott, Alyse R. Bedell, Allistair L. Clark, Muskaan Mehra, Omer Liran, Rajsavi Anand, Robert Chernoff, Lauren C. Capucci, Brennan M. R. Spiegel, and David T. Rubin. Inflammatory Bowel Diseases, November, izag208.
TREM2 Drives Monocyte-Derived Macrophage Responses to Cryptococcus Neoformans. Abass, Adiza, Alison Ricafrente, Apurwa Trivedi, Amy Vichaidit, Aelita Arshakyan, Sreemoyee Acharya, and Lena J. Heung. Infection and Immunity, November, e0036426.
Neurology
The Role of the Corrugator Supercilii and Its Impact on the Evolution of Migraine Medicine: A Narrative Review. Blumenfeld, Andrew, and Katrina A. Pasao. Headache, November.
OBGYN
The Association of Intrapartum Oral Labetalol for Preeclampsia With Severe Features and Risk of Cesarean Delivery: A Retrospective Cohort Study. Bronner, Baillie A., Margaret Schermerhorn, Monique Holod, Madeline Burds, Abigail Martin, Juliana Sung, Anna C. McCormick, and Samantha de Los Reyes. The Journal of Maternal-Fetal & Neonatal Medicine, 39 (1): 2758988.
Orthopaedics and Sports Medicine
Post-Treatment Follow-up, Rehabilitation, and Return to Sport: Proceedings of the International Consensus Meetings on Cartilage Repair of the Ankle. Rubin, Jared, Alexander Tham, James J. Butler, Paloma Gauthier, Davis Hedbany, John G. Kennedy, Niall A. Smyth, Christopher D. Murawski, Samuel B. Adams, Gregory C. Berlet, Roberto Buda, Sameh A. Labib, Zijun Zhang, et al. Foot & Ankle Specialist, November, 19386400261504161.
Pathology and Laboratory Medicine
Iptacopan in IgA Nephropathy - Final 24-Month Data. Haas, Mark. The New England Journal of Medicine 395 (19): 1969.
Superficial Ewing Sarcoma and Neurocristic FET::ETS Tumors: Defining a Diagnostic Gray Zone. Malik, Faizan, Karen J. Fritchie, Baptiste Ameline, Michael Michal, Zsombor Melegh, Catherine K. Gestrich, Laura M. Warmke, Bonnie Balzer, Paul W. Harms, Kyle D. Perry, Selene C. Koo, Travis Hattery, John M. Gross, Gregory W. Charville, Klaus Busam, Darcy Kerr, Andrew E. Rosenberg, Daniel Baumhoer, Steven D. Billings, Konstantinos Linos, Andrew L. Folpe, Josephine K. Dermawan, and Carina A. Dehner. Modern Pathology, Inc, November, 101113.
Pediatrics
A Spatiotemporal Cancer Cell Trajectory Underlies Glioblastoma Heterogeneity. Jong, Grant de, Fani Memi, Tannia Gracia, Olga Lazareva, Oliver Gould, Georgios Solomou, Alexander Aivazidis, Manas Dave, Qianqian Zhang, Melanie Jensen, Ahmet Sureyya Rifaioglu, Joao D. Barros-Silva, Omer Ali Bayraktar, et al. Nature, November.
Routine Fetal Cardiac Screening Versus Screening Fetal Echocardiography: Reconsidering the Distinction. Sklansky, Mark S. Journal of Ultrasound in Medicine, November.
Physical Medicine & Rehabilitation
Current State of Postoperative Rehabilitation Protocols for Upper Extremity Nerve Transfers: A Review of the Literature. Barrientos, Alberto, Omer Sadeh, Kevin Kuan-I Lee, Lori Ragni, April O’Connell, Anne Genzelev, Jonathan Bekisz, and Jacques H. Hacquebord. Journal of Hand Therapy, November, S0894-1130(26)00109-2.
Surgery
Cellular and Histopathological Hallmarks of Acute and Chronic Rejection in Vascular Composite Allografts: A Systematic Review. Knoedler, Leonard, Tobias Niederegger, Jakob Fenske, Murtaja Satea, Alessia Taggiasco, Guilherme F. Machado, Thomas Schaschinger, Romane Gaillard, Jadyn Heffern, Jasper Iske, Maximilian Richter, Max Heiland, Curtis L. Cetrulo, Haïzam Oubari, and Alexandre G. Lellouch. Clinical Transplantation 40 (11): e70744.
Early Surgical Resection and Survival in Patients With Stage I Non–Small Cell Lung Cancer. Krishna, Vikram, Claire Perez, Drew Bolster, Kellie Knabe, Raffaele Rocco, Philicia Moonsamy, Clark B. Fuller, Harmik J. Soukiasian, and Andrew R. Brownlee. JAMA Network Open 9 (11): e2643684.
Long-Term Outcomes After Medical and Surgical Management of Blunt Traumatic Aortic Injury. Ayouty, Mohyee, Joseph J. DuBose, Marvin Lu, Lara Schwieger, Donna Bahroloomi, Donald Baril, Elizabeth L. Chou, Cassra Arbabi, NavYash Gupta, Ali Azizzadeh, and Aortic Trauma Foundation. Annals of Vascular Surgery, November, S0890-5096(26)00778-8.
Response to: Mechanistic Plausibility Should Not Be Conflated With Clinical Validation of GHK-Cu. Mokhtar, Jonathan, and Alexandre G. Lellouch. Aesthetic Surgery Journal, November, sjag248.
Return to Normalcy: Determinants of Decannulation and Oral Feeding Readiness in Trauma Patients With Tracheostomy and Gastrostomy Tubes. Maneval, Andrew, Sophie Gonzalez, Devon Callahan, Tejal S. Brahmbhatt, Yassar Hashim, Rex Chung, Daniel R. Margulies, and Galinos Barmparas. American Journal of Surgery 263 (October): 117342.
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