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September
2025
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Faculty Publications Sept. 11-17

A Comprehensive Digest of Research Publications From Cedars-Sinai Investigators and a Sampling of Recent Media Coverage Featuring Faculty

This week’s edition of Faculty Publications includes Cedars-Sinai studies that were published Sept. 11-17. If you have a published paper from this period that does not appear on this list, please contact Sue Marone.

 

Cedars-Sinai in the News

What Doctors Think of the 3x3 By 12 Morning Routine That’s all Over Tiktok | Prevention
Bert Mandelbaum, MD 

The Unexpected Heart Attack Risk for Women Under 65 | WebMD
Janet Wei, MD 

8 Myths About Colon Cancer Debunked | Everyday Health
Jun Gong, MD 

The Vexing Promise of New Blood Tests for Alzheimer’s | Scientific American
Zaldy Tan, MD, MPH 

Women Still Underrepresented in Cardiovascular Trials | HealthDay
Susan Cheng, MD 

New Guidelines for IBD Treatment in Pregnancy: Here's What to Know | MedPage Today
Puja Khanna, MD 

‘Promising’ New Data Could Change Treatment Landscape for Some Rare Diseases | Healio Endocrine Today
Laurence Katznelson, MD; Odelia Cooper, MD

Lupus: 11 Things Doctors Want You to Know | Healthgrades
Swamy Venuturupalli, MD

 

Faculty Publications

Biomedical Sciences

Parent-Focused Behavioural Interventions for the Prevention of Early Childhood Obesity (TOPCHILD): A Systematic Review and Individual Participant Data Meta-Analysis. Hunter, Kylie E., David Nguyen, Sol Libesman, Jonathan G. Williams, Mason Aberoumand, Jannik Aagerup, Brittany J. Johnson, Rebecca K. Golley, Angie Barba, James X. Sotiropoulos, Nipun Shrestha, Talia Palacios, TOPCHILD Collaboration, et al. Lancet (London, England), September, S0140-6736(25)01144-4.

Mapping Behavioural Interventions to Reduce Sugar-Sweetened Beverage (SSB) Consumption Among US Adults: A Scoping Review Protocol. Cruz, Jailene, Horacio Palma, Caroline D. Marshall, Yelba Castellon-Lopez, Geetanjali D. Datta, and Vanessa Torres. BMJ Open 15 (9): e096007.

Cardiac Surgery

Biomarker Potential of Vanin-1-Derived Pantothenic Acid in Diabetes and Its Associated Cardiovascular Complications. Shoura, Nada K., Mahmoud H. Elbatreek, Mayada M. Mousa, Hany M. El-Bassossy, and Omar Y. El-Azzazy. Scientific Reports 15 (1): 32549.

Dysregulated Protein S-Nitrosylation Promotes Nitrosative Stress and Disease Progression in Heart Failure With Preserved Ejection Fraction. Li, Zhen, Kyle B. LaPenna, Natalie D. Gehred, Xiaoman Yu, W. H. Wilson Tang, Jake E. Doiron, Huijing Xia, Jingshu Chen, Ian H. Driver, Frank B. Sachse, Naoto Muraoka, Antonia Katsouda, Paraskevas Zampas, Amelia G. Haydel, Heather Quiriarte, Timothy D. Allerton, Alexia Zagouras, Jennifer Wilcox, Tatiana Gromova, Yueqin Zheng, Andreas Papapetropoulos, Sanjiv J. Shah, Traci T. Goodchild, Martin B. Jensen, Thomas E. Sharp, Thomas M. Vondriska, and David J. Lefer. Circulation Research, September.

Cardiology

Characterizing Longitudinal Blood Pressure Trajectories in Patients at High Risk for de Novo Postpartum Hypertension: A Randomized Controlled Trial Secondary Analysis. Emeruwa, Ukachi N., Minhazur R. Sarker, Natalie Bello, Marni Jacobs, Louise C. Laurent, E. Nicole Teal, Timothy Wen, Russell S. Miller, and Cynthia Gyamfi-Bannerman. Pregnancy (Hoboken, N.J.) 1 (3).

Anemia as a Potent Marker of In-Hospital Mortality in Patients Admitted to the Cardiac Intensive Care Unit: Data From the Critical Care Cardiology Trials Network (CCCTN) Registry. Chow, Christine, Rasheed Durowoju, Carlos Alviar, Gregory W. Barsness, Howard A. Cooper, Lori B. Daniels, Xuan Ding, Shahab Ghafghazi, Umesh Gidwani, Michael Goldfarb, Dustin Hillerson, Jason N. Katz, Paul Marano, Jeong-Gun Park, Matthew Pierce, Scott W. Rose, Robert O. Roswell, Sean van Diepen, Anjali Wagle, Erin A. Bohula, David D. Berg, David A. Morrow, and Younghoon Kwon. Journal of Intensive Medicine 5 (3): 262–68.

Current Evidence-Based Treatment of Angina With Nonobstructive Coronary Arteries (ANOCA). Toleva, Olga, Nathaniel R. Smilowitz, Odayme Quesada, Manoj Kesarwani, Michael P. Savage, Megha Prasad, Ailin Barseghian El-Farra, Noa Holoshitz, Jeffrey W. Moses, William F. Fearon, Jennifer A. Tremmel, Bruce Samuels, Timothy D. Henry, and Microvascular Network. Journal of the Society for Cardiovascular Angiography & Interventions 4 (7): 102633.

Pioneers of Congenital Heart Disease Interventions. Ing, Frank F., Evan M. Zahn, Ziyad M. Hijazi, Audrey Marshall, and Robert H. Beekman. Journal of the Society for Cardiovascular Angiography & Interventions 4 (7): 103707.

The Total Artificial Heart: A Historical Perspective. Masarone, Daniele, Rita Gravino, Luigi Falco, Dario Catapano, Fabio Valente, Cristiano Amarelli, Claudio Marra, Michelle Kittleson, Pierino Di Silverio, and Emilio di Lorenzo. Journal of Clinical Medicine 14 (17): 6290.

Reassessing Pretest Probability: Coronary Artery Calcium Alone Predicts Obstructive CAD. Rozanski, Alan, Robert J. H. Miller, Heidi Gransar, Donghee Han, Sean W. Hayes, John D. Friedman, Leslee J. Shaw, and Daniel S. Berman. Journal of Cardiovascular Computed Tomography, September, S1934-5925(25)00427-7.

Computational Biomedicine

Health-Related Concerns of Anti-LGBTQ+ Legislation: Thematic Analysis Using Social Media Data. Klein, Ari Z., Kaelen Spiegel, José A. Bauermeister, and Graciela Gonzalez-Hernandez. JMIR Infodemiology 5 (September): e68956.

Medicine

Editorial: Epidemiological Investigations of Zoonotic Viruses and Research on Drugs and Vaccines. Ren, Jingqiang, Zhenzhen Zheng, Shen Yang, Xusheng Qiu, and Mingxiao Ma. Frontiers in Veterinary Science 12: 1674157.

hNIS-Based Imaging to Monitor Treatment With the Novel Oncolytic Virus CF33-hNIS-antiPDL1 in Humans With Advanced Triple Negative Breast Cancer. Rand, Jamie, Dave Yamauchi, Shyambabu Chaurasiya, Jianying Zhang, Supriya Deshpande, Leslie Chong, Amanda Seiz, Hans Meisen, Yuman Fong, and Yuan Yuan. Frontiers in Oncology 15: 1565244.

Vibratory Angioedema Due to Vigorous Nose Blowing: A Case Report. Truong, Tiffany, Timothy Kaddis, Vivian Wang, Monica Tsai, and Joseph Yusin. Cureus 17 (8): e90197.

Contemporary Changes in Global Trends in Early-Onset Cancer: Incidence and Mortality (2000-2021). Danpanichkul, Pojsakorn, Yanfang Pang, Supapitch Sirimangklanurak, Thanida Auttapracha, Thanawin Pramotedham, Chun Wei Pan, Benjamin Koh, Zhen Yu Wong, Sakditad Saowapa, Shyna Zhuoying Gunalan, Kwanjit Duangsonk, Chanakarn Kanitthamniyom, Donghee Kim, Karn Wijarnpreecha, Amit G. Singal, Daniel Q. Huang, and Ju Dong Yang. Cancers 17 (17): 2766.

Prevalence of BRCA1 and BRCA2 Variants in an Unselected Population of Women With Breast Cancer. Mortimer, Joanne E., Sidney S. Lindsey, Elyssa Zukin, Wai Park, Duveen Sturgeon, Ilana Solomon, Kathleen Blazer, Stacy W. Gray, Joseph D. Bonner, and Stephen B. Gruber. JAMA Network Open 8 (9): e2531577.

Integrating Perfusion With AI-Derived Coronary Calcium on CT Attenuation Scans to Improve Selection of Low-Risk Studies for Stress-Only SPECT MPI. Miller, Robert J. H., Orit Barrett, Aakash Shanbhag, Alan Rozanski, Damini Dey, Mark Lemley, Serge D. Van Kriekinge, Paul B. Kavanagh, Attila Feher, Edward J. Miller, Andrew J. Einstein, Terrence D. Ruddy, Timothy Bateman, Philip A. Kaufmann, Joanna X. Liang, Daniel S. Berman, and Piotr J. Slomka. Journal of Nuclear Cardiology, September, 102482.

Workload, Compensation, and Institutional Support Among U.S. Transplant Hepatologists: Results of a National Survey. Aby, Elizabeth S., Faruq Pradhan, Lindsay Y. King, Alexander Kuo, Alyson Fox, John P. Norvell, Neehar D. Parikh, Arjmand R. Mufti, Jacquelin Blomker, Kaeli Samson, Yue Zhan, and Anjana Pillai. Liver Transplantation, September.

Immunological and Regenerative Properties of Lung Stem Cells. Hao, De, Yimeng Liu, Li Li, Barry R. Stripp, and Huaiyong Chen. Physiological Reviews, September.

Increased Risk of Infections in Smoldering Multiple Myeloma: Results From the Screened iStopMM Study. Andersen, Lærke Sloth, Ricardo Berenguer Navarro, Sara Ekberg, Sæmundur Rögnvaldsson, Marína Rós Levy, Ingigerður Sólveig Sverrisdóttir, Brynjar Viðarsson, Páll Torfi Önundarson, Bjarni A. Agnarsson, Margrét Sigurðardóttir, Ingunn Þorsteinsdóttir, Ísleifur Ólafsson, Ásdís Rósa Þórðardóttir, Elías Eyþórsson, Ásbjörn Jónsson, Andri Ólafsson, Brian G. M. Durie, Stephen Harding, Ola Landgren, Thorvardur Jón Löve, Sigurður Yngvi Kristinsson, and Sigrún Thorsteinsdóttir. Leukemia, September.

Impact of Extended Risankizumab Treatment in Patients With Ulcerative Colitis Who Did Not Respond to Induction Treatment. Panaccione, Remo, Gil Y. Melmed, David Drobne, Manreet Kaur, Silvio Danese, Tadakazu Hisamatsu, Jasmina Kalabic, Su Chen, Ling Cheng, W. Rachel Duan, Saajan Shah, and Edouard Louis. Clinical Gastroenterology and Hepatology, September, S1542-3565(25)00797-9.

MASCC/ISOO Clinical Practice Statement: Dental Evaluation and Management Prior to Treatment for Hematologic Malignancies and CAR T-Cell Therapy. Zadik, Yehuda, Judith E. Raber-Durlacher, Joel B. Epstein, Alessandra Majorana, Wanessa Miranda-Silva, Sujin Yang, Nicole Blijlevens, and Sharon Elad. Supportive Care in Cancer, 33 (10): 853.

MASCC/ISOO Clinical Practice Statement: Imaging and Clinical Laboratory Tests in the Diagnosis and Management of Medication-Related Osteonecrosis of the Jaw. Yarom, Noam, Ragda Abdalla-Aslan, Cesar Migliorati, Elena Livshits, Mohammed Amir Rais, Wonse Park, Eduardo R. Fregnani, Kivanc Bektas-Kayhan, Joel Epstein, and Sharon Elad. Supportive Care in Cancer, 33 (10): 852.

MASCC/ISOO Clinical Practice Statement: Management of Oral Complications of Immunotherapy. Fregnani, Eduardo R., Joel B. Epstein, Nicole M. A. Blijlevens, Noam Yarom, Alessandro Villa, Judith E. Raber-Durlacher, Pamela J. Gardner, Dennis Shem, Sophie Beaumont, Paolo Bossi, and Sharon Elad. Supportive Care in Cancer, 33 (10): 851.

Advancing Biological Understanding of Cellular Senescence With Computational Multiomics. Li, Sheng, Paula A. Agudelo Garcia, Constantin Aliferis, Michael J. Becich, Jazmin Calyeca, Benjamin D. Cosgrove, Jennifer Elisseeff, Negin Farzad, Elana J. Fertig, Carolyn Glass, Liangcai Gu, Qianjiang Hu, SenNet Consortium, et al. Nature Genetics, September.

A Randomized, Placebo-Controlled Trial of Hydroxychloroquine in Incomplete Lupus. Olsen, Nancy J., Duanping Liao, Judith A. James, Joel M. Guthridge, Cristina Arriens, Diane Kamen, Mariko Ishimori, Daniel J. Wallace, Christopher Striebich, Sonali Narain, Benjamin F. Chong, Fan He, Eric W. Schaefer, Vernon M. Chinchilli, and David R. Karp. Arthritis & Rheumatology (Hoboken, N.J.), September.

Documentation of Menopause-Related International Classification of Diseases Codes in the Electronic Health Record in Midlife Women With Menopause Symptoms. Karam, Jana, Nancy Safwan, Rickey E. Carter, Joshua Pevnick, Carl Berdahl, Rajeev Chaudhry, Juliana M. Kling, Ekta Kapoor, Stacey J. Winham, Kristin Cole, Stephanie S. Faubion, and Chrisandra L. Shufelt. Menopause (New York, N.Y.), September.

Neurology

A Novel Convolutional Neural Network for Automated Multiple Sclerosis Brain Lesion Segmentation. Dereskewicz, Emma, Francesco La Rosa, Jonadab Dos Santos Silva, Edward Sizer, Amit Kohli, Maxence Wynen, William A. Mullins, Pietro Maggi, Sarah Levy, Kamso Onyemeh, Batuhan Ayci, Andrew J. Solomon, Jakob Assländer, Omar Al-Louzi, Daniel S. Reich, James Sumowski, and Erin S. Beck. Journal of Neuroimaging, 35 (5): e70085.

Feasibility and Acceptability of an In-Home Digital Device Health and Activity Assessment Platform in a Diverse South Texas Cohort: A Pilot Study. Mathews, Julia J., Rachel Mulavelil, Nathaniel Rodrigues, Tiffany F. Kautz, Kevin Cosgrove, Chen-Pin Wang, Daniel MacCarthy, Roman A. Fernandez, Sarah Gothard, Nicole Sharma, Luis Serranorubio, Vanessa M. Young, Lyndsey Miller, Sudha Seshadri, Jeffrey Kaye, Zachary T. Beattie, and Mitzi M. Gonzales. Frontiers in Digital Health 7: 1603062.

Neurosurgery

Medicare’s Benchmarking Spinal DRGs Have Limited Capacity in Capturing the Nuances of Surgical Invasiveness, Hospital Length of Stay, Discharge Disposition, Key Quality Metrics, and Reimbursement Costs for Adult Spinal Deformity. Theologis, Alekos A., Ayush Arora, Jeffrey Gum, Eric Klineberg, Munish C. Gupta, Richard Hostin, Khaled M. Kebaish, Justin K. Scheer, Alan Daniels, Renaud Lafage, Justin Smith, Peter Passias, Themistocles Protopsaltis, Han Jo Kim, Michael P. Kelly, Alex Soroceanu, Christopher Shaffrey, Frank Schwab, Robert Hart, Douglas Burton, Larry G. Lenke, Virginie Lafage, Shay Bess, Chistopher P. Ames, and International Spine Study Group (ISSG). Spine, September.

Factors Associated With Early Neurological Deterioration in Minor Distal Medium Vessel Acute Ischemic Stroke: A Multinational Multicenter Study. Lakhani, Dhairya A., Hamza A. Salim, Vivek Yedavalli, Basel Musmar, Fathi Milhem, Nimer Adeeb, Tobias Djamsched Faizy, Motaz Daraghma, Kareem El Naamani, Nils Henninger, Sri Hari Sundararajan, Anna Kuhn, Adam Dmytriw, et al. International Journal of Stroke, September, 17474930251381946.

Five-Year Outcomes from Deep Brain Stimulation of the Subthalamic Nucleus for Parkinson Disease. Starr, Philip A., Rajat S. Shivacharan, Edward Goldberg, Alexander I. Tröster, Paul A. House, Monique L. Giroux, Adam O. Hebb, Donald M. Whiting, Timothy A. Leichliter, Jill L. Ostrem, Leo Verhagen Metman, Sepehr Sani, Jessica A. Karl, Mustafa S. Siddiqui, Stephen B. Tatter, Ihtsham Ul Haq, Andre G. Machado, Michal Gostkowski, Michele Tagliati, Adam N. Mamelak, Michael S. Okun, Kelly D. Foote, Guillermo Moguel-Cobos, Francisco A. Ponce, Rajesh Pahwa, Kelly Lyons, Cathrin M. Buetefisch, Robert E. Gross, Corneliu C. Luca, Jonathan R. Jagid, Gonzalo J. Revuelta, Istvan Takacs, Michael H. Pourfar, Alon Y. Mogilner, Andrew P. Duker, George T. Mandybur, Joshua M. Rosenow, Cindy Zadikoff, Suketu M. Khandhar, Mark Sedrak, Fenna T. Phibbs, Joseph Neimat, Jennifer Durphy, Adolfo Ramirez-Zamora, Julie G. Pilitsis, Ryan J. Uitti, Robert Wharen, Michael C. Park, Jerrold L. Vitek, and INTREPID Study Group. JAMA Neurology, September, e253373.

OBGYN

Changes in Placentas of Pregnant Women Infected With COVID-19. Kramar, Solomiia, Zoia Nebesna, Yuliia Yakymchuk, Alla Boychuk, Oksana Shevchuk, Mykhaylo Korda, and Sandor George Vari. International Journal of Molecular Sciences 26 (17): 8596.

Adjuvant Radiotherapy for Early-Stage Endometrial Cancer Based on Randomized Controlled Trials: A Narrative Review. Levin, Gabriel, Susie Lau, Shannon Salvador, Melica Brodeur, Raanan Meyer, and Walter Gotlieb. Minerva Obstetrics and Gynecology, September.

M2 Macrophages Are Major Mediators of Germline Risk of Endometriosis and Explain Pleiotropy With Comorbid Traits. Ochoa, Soledad, Fernanda S. Rasquel-Oliveira, Brett McKinnon, Marcela Haro, Sugarniya Subramaniam, Pak Yu, Simon Coetzee, Michael S. Anglesio, Kelly N. Wright, Raanan Meyer, Anne E. Porter, Caroline E. Gargett, Sally Mortlock, Grant W. Montgomery, Michael S. Rogers, and Kate Lawrenson. Advanced Science (Weinheim, Baden-Wurttemberg, Germany), September, e15285.

Orthopaedics 

Faculty Diversity Associated With Decreased Orthopaedic Surgery Resident Attrition. Chen, Xi, Hiroko Matsumoto, Lee S. Haruno, Melodie F. Metzger, Carol A. Lin, Milton T. M. Little, and Selina C. Poon. JB & JS Open Access 10 (3): e24.00135.

Radiation Oncology

End Points for the Next-Generation Bladder-Sparing Perioperative Trials for Patients With Muscle-Invasive Bladder Cancer. Necchi, Andrea, Matthew D. Galsky, Nazli Dizman, David H. Aggen, Neeraj Agarwal, Hikmat Al-Ahmadie, Andrea B. Apolo, Leslie Ballas, Rick Bangs, Peter C. Black, Maurizio Brausi, Giorgio Brembilla, Liang Cheng, Arturo Chiti, Alessia Cimadamore, Maurizio Colecchia, Siamak Daneshmand, Savino Di Stasi, Jason A. Efstathiou, Alex Filicevas, Daniel M. Geynisman, Petros Grivas, Shilpa Gupta, Alexia Iasonos, Nick D. James, Seth P. Lerner, Yohann Loriot, Lydia E. Makaroff, Fernando Maluf, Marco Moschini, Irina Ostrovnaya, Sumanta K. Pal, Elizabeth R. Plimack, Gagan Prakash, Sarah P. Psutka, Jonathan E. Rosenberg, Sarmad Sadeghi, Bogdana Schmidt, Lawrence H. Schwartz, Guru P. Sonpavde, Marie-Pier St Laurent, Dingwei Ye, Philippe E. Spiess, and Ashish M. Kamat. Journal of Clinical Oncology, September, JCO2501608.

Surgery 

Wait Times Between Lung Cancer Diagnosis and Surgery: National Trends, Disparities, and Impact on Long-Term Survival. Perez, Claire, Andrew R. Brownlee, Lucas Weiser, Justin J. J. Watson, Kellie Knabe, Charles Fuller, Shruthi Nammalwar, Qiudong Chen, Raffaele Rocco, and Harmik J. Soukiasian. Journal of Thoracic Disease 17 (8): 5983–92.

SAGES Guidelines for the Use of Intraoperative Imaging of the Common Bile Duct. Kumar, Sunjay K., Dena G. Shehata, Lawrence N. Cetrulo, Romeo Ignacio, Jeffrey Chiu, Brain R. Davis, Marian McDonald, Matthew B. Bloom, Subhashini Ayloo, Ali Kchaou, Georgios Orthopoulos, Philip H. Pucher, Uretz Oliphant, Peter T. Hallowell, Federico Serrot, David Overby, Eduardo Moreno-Paquentin, Bethany J. Slater, and Emily Miraflor. Surgical Endoscopy, September.

Project Interpret Cholangiogram at the SAGES 2024 Education & Innovation Center: Skill Deficiency in Bile Duct Injury Recognition Among Surgical Residents. Hannah, Emily M., Matthew B. Bloom, and Steven D. Schwaitzberg. Surgical Endoscopy, September.

Lateral Support Maneuver: Validation of a Diagnostic Tool Specific to Dynamic Nasal Valve Collapse. Pak, Kaitlynne Y., Alberto Nunez, and Matthew K. Lee. The Journal of Craniofacial Surgery, September.

Urology

Comparing the Safety and Efficacy of Systemic Therapies for High-Risk Biochemically Recurrent Hormone-Sensitive Prostate Cancer: A Network Meta-Analysis. Aprikian, Armen, Andrew Chilelli, Thomas McLean, Anchen Nasr, Arijit Ganguli, Alexis Serikoff, Franco Guzman, Ifigeneia Barouma, Maria Zacharioudaki, and Stephen J. Freedland. Frontiers in Oncology 15: 1638405.

Association Between Insulin Resistance and Prostate Volume: A 4-Year Analysis From the Reduction by Dutasteride of Prostate Cancer (REDUCE) Trial. Daniels, James P., Alexander Hernández-Tirado, James Mirocha, Renning Zheng, Jordan Palmer, Daniel Moreira, and Stephen J. Freedland. BJUI Compass 6 (9): e70085.

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