Faculty Publications Oct. 17-24

This week’s edition of Faculty Publications includes Cedars-Sinai studies that were published Oct. 17-24. If you have a published paper from this period that does not appear on this list, please contact Sue Marone.

Cedars-Sinai in the News

I Knew my Chest Pains Weren’t Normal but Doctors Sent me Home—A Single Phone Call Saved My Life | Prevention Online
Martha Gulati, MD 

Young Breast Cancer Patient Documents Story | KABC-TV
Yuan Yuan, MD, PhD 

Do Vitamin D & Genomic Ancestry Affect Cancer Cells?: An Expert Explains | Finding Genius Podcast
Moray J. Campbell, PhD 

New CEO Takes the Reins at Cedars-Sinai | Hospital Association of Southern California
Peter Slavin, MD 

TAVI Explant Complications a ‘Big Issue’ as Procedure Numbers Climb | TCTMD
Michael Bowdish, MD

Your Health—Expert Insights: Navigating a Breast Cancer Diagnosis | Pasadena Now
Jeannie Shen, MD

Faculty Publications

Biomedical Sciences

Integrating Priorities at the Intersection of Cancer and Neuroscience. Hwang, William L., Ella N. Perrault, Alexander Birbrair, Brandi J. Mattson, David H. Gutmann, Donald J. Mabbott, Edna Cukierman, Elizabeth A. Repasky, Erica K. Sloan, Hui Zong, Ihsan Ekin Demir, Jami L. Saloman, Jeremy C. Borniger, Jian Hu, Jorg Dietrich, Joshua J. Breunig, Kaan Çifcibaşı, Khalil Ali Ahmad Kasm, Manuel Valiente, Max Wintermark, Munjal M. Acharya, Nicole N. Scheff, Nisha J. D’Silva, Paola D. Vermeer, Richard J. Wong, Sebastien Talbot, Shawn L. Hervey-Jumper, Timothy C. Wang, Yi Ye, Yuan Pan, Yuri L. Bunimovich, and Moran Amit. Cancer Cell, October, S1535-6108(24)00362-3.

The Homeodomain Regulates Stable DNA Binding of Prostate Cancer Target ONECUT2. Chatterjee, Avradip, Brad Gallent, Madhusudhanarao Katiki, Chen Qian, Matthew R. Harter, Steve Silletti, Elizabeth A. Komives, Michael R. Freeman, and Ramachandran Murali. Nature Communications 15 (1): 9037.

Cardiac Surgery

Allele-Specific Dysregulation of Lipid and Energy Metabolism in Early-Stage Hypertrophic Cardiomyopathy. Vaniya, Arpana, Anja Karlstaedt, Damla Gulkok, Tilo Thottakara, Yamin Liu, Sili Fan, Hannah Eades, Styliani Vakrou, Ryuya Fukunaga, Hilary J. Vernon, Oliver Fiehn, and M. Roselle Abraham. Journal of Molecular and Cellular Cardiology Plus 8 (June): 100073.

Cardiology

Cardio-Oncology and Heart Failure: A Scientific Statement From the Heart Failure Society of America. Bloom, Michelle Weisfelner, Jacqueline B. Vo, Jo Ellen Rogers, Alana Ferrari, Anju Nohria, Anita Deswal, Richard K. Cheng, Michelle M. Kittleson, Jenica N. Upshaw, Nicholas Palaskas, Anne Blaes, Sherry-Ann Brown, Bonnie Ky, Daniel Lenihan, Mathew S. Maurer, Anecita Fadol, Kerry Skurka, Christine Cambareri, Cynthia Chauhan, and Ana Barac. Journal of Cardiac Failure, September, S1071-9164(24)00363-4.

A Recurrent Typical Angina Pectoris Without Any Finding in Coronary Angiography: Microvascular Angina. Taheri, Homa, Maryam Taheri, Pouya Ebrahimi, Parnian Soltani, Amin Zaki Zadeh, and Mohsen Anafje. Clinical Case Reports 12 (10): e9475.

What Is the Significance of Greater Global Wasted Work in Patients With Apical Hypertrophic Cardiomyopathy and Apical Aneurysm? Is It the Chicken or the Egg? Pollick, Charles. Echocardiography (Mount Kisco, N.Y.) 41 (10): e70010.

Design and Rationale of a Pragmatic Randomized Clinical Trial of Early Dronedarone Versus Usual Care to Change and Improve Outcomes in Persons With First-Detected Atrial Fibrillation - The CHANGE AFIB Study. Pokorney, Sean D., Hayley Nemeth, Karen Chiswell, Christine Albert, Nadine Allyn, Rosalia Blanco, Javed Butler, Hugh Calkins, Mitchell S. V. Elkind, Gregg C. Fonarow, John M. Fontaine, David S. Frankel, Gregory J. Fermann, Rex Gale, Matthew Kalscheur, Paulus Kirchhof, Andrew Koren, Joseph B. Miller, Jason Rashkin, Andrea M. Russo, Christine Rutan, Benjamin Steinberg, and Jonathan P. Piccini. American Heart Journal, October, S0002-8703(24)00263-1.

A Proteomics Pipeline for Generating Clinical Grade Biomarker Candidates From Data-Independent Acquisition Mass Spectrometry (DIA-MS) Discovery. Fu, Qin, Manasa Vegesna, Niveda Sundararaman, Eugen Damoc, Tabiwang N. Arrey, Anna Pashkova, Emebet Mengesha, Philip Debbas, Sandy Joung, Dalin Li, Susan Cheng, Jonathan Braun, Dermot Govern, Christopher Murray, Yue Xuan, and Jennifer E. Van Eyk. Angewandte Chemie (International Ed. in English), October, e202409446.

Characterization and Z-Score Calculation of Cardiac MRI Parameters in Patients After the Fontan Operation. A Fontan Outcome Registry Using CMR Examinations (FORCE) Study. Alsaied, Tarek, Runjia Li, Adam Christopher, Mark Fogel, Timothy C. Slesnick, Rajesh Krishnamurthy, Vivek Muthurangu, Adam L. Dorfman, Christopher Z. Lam, Justin Weigand, Jong-Hyeon Jeong, Joshua D. Robinson, Laura J. Olivieri, Rahul H. Rathod, and FORCE Investigators. Journal of Cardiovascular Magnetic Resonance, October, 101113.

Diagnostic and Therapeutic Challenges in Rapidly Progressing Cardiac Amyloidosis: A Literature Review Based on Case Report. Senobari, Nahid, Roozbeh Nazari, Pouya Ebrahimi, Hamidreza Soleimani, Maryam Taheri, Kaveh Hosseini, Homa Taheri, and Robert J. Siegel. International Journal of Emergency Medicine 17 (1): 159.

Guidelines for Treating Heart Failure. Kittleson, Michelle M. Trends in Cardiovascular Medicine, October, S1050-1738(24)00093-8.

PAD Inhibition Downregulates the Cellular Fibrotic Behavior of Senescent Myofibroblasts Derived From Dilated Cardiomyopathy. Sadiq, Alia, and Justyna Fert-Bober. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie 180 (October): 117579.

Computational Biomedicine

Three-Year Effects of Motivational Interviewing-Enhanced Behavior Therapy for Adolescents With ADHD: A Randomized Community-Based Trial. Sibley, Margaret H., Paulo A. Graziano, Stefany Coxe, Timothy F. Page, and Pablo Martin. Journal of the American Academy of Child and Adolescent Psychiatry, October, S0890-8567(24)01948-8.

Lynch Syndrome Diagnostic Testing Pathways in Endometrial Cancers: A Nationwide English Registry-Based Study. Loong, Lucy, Catherine Huntley, Joanna Pethick, Fiona McRonald, Francesco Santaniello, Brian Shand, Oliver Tulloch, Shilpi Goel, Margreet Lüchtenborg, Sophie Allen, Bethany Torr, Katie Snape, Angela George, Fiona Lalloo, Gail Norbury, Diana M. Eccles, Marc Tischkowitz, Antonis C. Antoniou, Paul Pharoah, Adam Shaw, Eva Morris, John Burn, Kevin Monahan, Steven Hardy, and Clare Turnbull. Journal of Medical Genetics, October, jmg-2024-110231.

Medicine

Bacterial Metabolites Influence the Autofluorescence of Clostridioides Difficile. Ticer, Taylor D., Anna M. Tingler, Janiece S. Glover, Sarah A. Dooley, Jacob Kendrick, Joseph P. Zackular, Suzanne Devkota, Gary D. Wu, Karley Mahalak, Amy Engevik, and Melinda A. Engevik. Frontiers in Microbiology 15: 1459795.

Widespread Impact of Natural Genetic Variations in CRISPR-Cas9 Outcomes. Li, Victoria R., Tinghui Wu, Alicja Tadych, Aaron Wong, and Zijun Zhang. The CRISPR Journal 7 (5): 283–92.

Venture Capital in Retreat: Funding Trends in Gastroenterology Over the Past Decade. Busam, Jonathan A., and Eric D. Shah. Clinical Gastroenterology and Hepatology, October, S1542-3565(24)00901-7.

FAM13A Polymorphism Is Associated With a Usual Interstitial Pneumonia Pattern in Patients With Systemic Sclerosis-Associated Interstitial Lung Disease. Bernstein, Elana J., Francesco Boin, Brett Elicker, Yiming Luo, Yawen Ren, Meng Zhang, John Varga, and Shervin Assassi. Rheumatology (Oxford, England), October, keae573.

Outcomes After Brexucabtagene Autoleucel Administered as a Standard Therapy for Adults With Relapsed/Refractory B-Cell ALL. Roloff, Gregory W., Ibrahim Aldoss, Noam E. Kopmar, Chenyu Lin, Simone E. Dekker, Vishal K. Gupta, Timothy E. O’Connor, Nikeshan Jeyakumar, Ibrahim N. Muhsen, Yannis Valtis, Naveed Ahmed, Amy Zhang, Katharine Miller, Kaitlyn C. Dykes, Mohamed Ahmed, Evan C. Chen, Santiago Mercadal, Marc Schwartz, Sean I. Tracy, Bhagirathbhai Dholaria, Akash Mukherjee, Minoo Battiwalla, Aaron C. Logan, Abdullah Ladha, Caitlin Guzowski, Rasmus T. Hoeg, Talal Hilal, Jozal Moore, Matthew P. Connor, LaQuisa C. Hill, Stephanie B. Tsai, Joshua P. Sasine, Melhem M. Solh, Vamsi K. Kota, Divya Koura, Muthu Veeraputhiran, Jessica T. Leonard, Noelle V. Frey, Jae H. Park, Marlise R. Luskin, Veronika Bachanova, Ahmed Galal, Vinod Pullarkat, Wendy Stock, Ryan D. Cassaday, Bijal D. Shah, Rawan Faramand, Lori Muffly, and ROCCA Consortium. Journal of Clinical Oncology, October, JCO2400321.

The Occurrence of Senescence in the Arteriovenous Fistula in the Rat. Nath, Karl A., Luis A. Juncos, Raman Deep Singh, Joseph P. Grande, Anthony J. Croatt, Allan W. Ackerman, Karina S. Kanamori, Christopher M. Adams, Tamara Tchkonia, James L. Kirkland, and Zvonimir S. Katusic. Kidney360, October.

Neuropeptide Precursor VGF Promotes Liver Metastatic Colonization of Gαq Mutant Uveal Melanoma by Facilitating Tumor Microenvironment via Paracrine Loops. Ouyang, Shumin, Shuo Shi, Wen Ding, Yang Ge, Yingxue Su, Jianshan Mo, Keren Peng, Qiyi Zhang, Guopin Liu, Wei Xiao, Peibin Yue, Jinjian Lu, Yandong Wang, Xiaofeng Xiong, and Xiaolei Zhang. Advanced Science (Weinheim, Baden-Wurttemberg, Germany), October, e2407967.

Unionization of Graduate Medical Education Trainees: Perspectives From Designated Institutional Officials. Co, John Patrick T., Laurence Katznelson, Susan Guralnick, and Jeffrey S. Berns. Academic Medicine: Journal of the Association of American Medical Colleges, October.

Clinical and Demographic Factors Determining Patient Fracture Risk Decision Point (FRDP): The Improving Risk Communication in Osteoporosis (RICO) Project. Sharma, Mitali, Charlotte Beaudart, Patricia Clark, Saeko Fujiwara, Jonathan D. Adachi, Alexandra Papaioannou, Osvaldo D. Messina, Suzanne N. Morin, Lynn Kohlmeier, Xavier Nogues, Carolyn Leckie, Nicholas C. Harvey, John A. Kanis, Jean-Yves Reginster, Mickael Hiligsmann, and Stuart L. Silverman. Osteoporosis International: A Journal Established as Result of Cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, October.

DKN-01 in Combination With Tislelizumab and Chemotherapy as First-Line Therapy in Advanced Gastric or Gastroesophageal Junction Adenocarcinoma: DisTinGuish. Klempner, Samuel J., Mohamad Bassam Sonbol, Zev A. Wainberg, Hope Elizabeth Uronis, Vi K. Chiu, Aaron James Scott, Syma Iqbal, Mohamedtaki Abdulaziz Tejani, Vincent Chung, Melissa C. Stilian, Mathis Thoma, Ying Zhang, Michael H. Kagey, Jason Baum, Cynthia A. Sirard, Rachel A. Altura, and Jaffer A. Ajani. Journal of Clinical Oncology, October, JCO2400410.

Senolytics To slOw Progression of Sepsis (STOP-Sepsis) in Elderly Patients: Study Protocol for a Multicenter, Randomized, Adaptive Allocation Clinical Trial. Silva, Milena, David A. Wacker, Brian E. Driver, Abbey Staugaitis, Laura J. Niedernhofer, Elizabeth L. Schmidt, James L. Kirkland, Tamara Tchkonia, Tamara Evans, Carlos Hines Serrano, Steffen Ventz, Joseph S. Koopmeiners, Michael A. Puskarich, and STOP-Sepsis Investigators. Trials 25 (1): 698.

Progression of Crohn’s Disease in Newly Diagnosed Patients: Results From an Observational Study Using US Claims Data. Fan, Yanni, Ling Zhang, Negar Omidakhsh, Rhonda L. Bohn, Kathleen Putnam, A. Shola Adewale, and Gil Y. Melmed. Digestive Diseases and Sciences, October.

Neurology

Microglia Ameliorate Delirium-Like Phenotypes in a Murine Model of Acute Ventilator-Induced Lung Injury. Scott, Landon, Kevin D. Winzey, Debbie Moreira, Catherine Bresee, Jean-Philippe Vit, Warren G. Tourtellotte, S. Ananth Karumanchi, and Shouri Lahiri. Journal of Neuroinflammation 21 (1): 270.

‘Lupus Myelitis’ Revisited: A Retrospective Single-Center Study of Myelitis Associated With Rheumatologic Disease. Krett, Jonathan D., Angeliki G. Filippatou, Paula Barreras, Carlos A. Pardo, Allan C. Gelber, and Elias S. Sotirchos. Neurology(R) Neuroimmunology & Neuroinflammation 12 (1): e200329.

Neurosurgery

Endovascular Therapy Versus Medical Management in Isolated Posterior Cerebral Artery Acute Ischemic Stroke: A Multinational Multicenter Propensity Score-Weighted Study. Salim, Hamza Adel, Benjamin Pulli, Vivek Yedavalli, Basel Musmar, Nimer Adeeb, Dhairya Lakhani, Muhammed Amir Essibayi, Kareem El Naamani, Nils Henninger, Sri Hari Sundararajan, Anna Luisa Kühn, Jane Khalife, Adam A. Dmytriw, et al. European Stroke Journal, October, 23969873241291465.

OBGYN

Trends and Regional Differences for Fertility Preservation Procedures in Women With Breast Cancer. Turan, Volkan, Giuliano Bedoschi, Dong-Yun Lee, Caio Parente Barbosa, Renato de Oliveira, Koray Gorkem Sacinti, Murat Sonmezer, Matteo Lambertini, Claudia Massarotti, Amelia Schaub, Erica Wang, Sonia Gayete-Lafuente, Cheryl Dunlop, Richard A. Anderson, Heejung Bang, and Kutluk H. Oktay. Clinical Breast Cancer, September, S1526-8209(24)00270-2.

Risk Factors for Major Complications Following Pelvic Exenteration: A NSQIP Study. Levin, Gabriel, Brian Slomovitz, Jason D. Wright, Rene Pareja, Kacey M. Hamilton, Rebecca Schneyer, Matthew T. Siedhoff, Kelly N. Wright, Yosef Nasseri, Moshe Barnajian, and Raanan Meyer. European Journal of Surgical Oncology: The Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology 50 (12): 108761.

Psychiatry & Behavioral Neurosciences

Describing the Framework for AI Tool Assessment in Mental Health and Applying It to a Generative AI Obsessive-Compulsive Disorder Platform: Tutorial. Golden, Ashleigh, and Elias Aboujaoude. JMIR Formative Research 8 (October): e62963.

Radiation Oncology

Quality and Safety Considerations for Adaptive Radiation Therapy: An ASTRO White Paper: ASTRO ART Safety White Paper. Chetty, Indrin J., Bin Cai, Michael D. Chuong, Samantha L. Dawes, William A. Hall, Amanda R. Helms, Suzanne Kirby, Eric Laugeman, Michelle Mierzwa, Jennifer Pursley, Xenia Ray, Ergys Subashi, and Lauren E. Henke. International Journal of Radiation Oncology, Biology, Physics, October, S0360-3016(24)03474-6.

Stereotactic Body Radiation Therapy for Primary Lung Cancer and Metastases: A Case Based Discussion on Challenging Cases. Ladbury, Colton, Baho Sidiqi, Nate Cantrell, Gavin Jones, Karin A. Skalina, Fatemeh Fekrmandi, Therese Y. Andraos, Emile Gogineni, Jennifer Dolan, Shankar Siva, Ben Slotman, and Percy Lee. Practical Radiation Oncology, October, S1879-8500(24)00275-3.

Surgery

Temperature-Controlled Radiofrequency Treatment of the Nasal Valve in Nasal Airway Obstruction Patients With Septal Deviation. Tang, Dennis M., Philip G. Chen, Arthur W. Wu, and William C. Yao. International Forum of Allergy & Rhinology, October.

Correlation Between Medical School Performance and Receiving Awards in General Surgery Residency. Ugarte, Ramsey, Christian de Virgilio, Amanda C. Purdy, Juliana Tolles, Ross J. Fleischman, George Singer, Brian R. Smith, Farin Amersi, Mayank Roy, Benjamin T. Jarman, Amy Y. Han, Karen J. Dickinson, Edgardo S. Salcedo, Edgar Shields Frey, V. Prasad Poola, Esther Wu, Chad Cryer, Catherine Lewis, and Kristine E. Calhoun. Journal of Surgical Education 81 (12): 103250.

Testing Neuroprotective Strategies in Prolonged Field Care Model of Traumatic Brain Injury and Hemorrhagic Shock. Bhatti, Umar F., Zaiba Shafik Dawood, Zhenhua Shang, Guang Jin, Marjorie R. Liggett, Kiril Chtraklin, Baoling Liu, Ramon-Lorenzo Redondo, Bowen Wang, and Hasan B. Alam. Journal of the American College of Surgeons, October.

Clinical and Financial Validation of the International Study Group for Pancreatic Surgery (ISGPS) Definition of Post-Pancreatectomy Acute Pancreatitis (PPAP): International Multicenter Prospective Study. Bannone, Elisa, Alice Cattelani, Gaetano Corvino, Alessio Marchetti, Valentina Andreasi, Francesca Fermi, Stefano Partelli, Nicolò Pecorelli, Domenico Tamburrino, Alessandro Esposito, Giuseppe Malleo, Manish Bhandare, International Study Group for Pancreatic Surgery (ISGPS), et al. Annals of Surgery, October.

Urology

Experiences and Preferences of Women With CAH and Parents About Disclosure of Childhood Surgery. Johnston, Ashley W., Mimi S. Kim, Paul Kokorowski, Devon J. Hensel, Patrice M. Yasuda, Richard C. Rink, Konrad M. Szymanski, and Life With Congenital Adrenal Hyperplasia. Journal of Pediatric Urology, October, S1477-5131(24)00518-7.