Faculty Publications Nov. 21-Dec.5

This week’s edition of Faculty Publications includes Cedars-Sinai studies that were published Nov. 21-Dec. 5. If you have a published paper from this period that does not appear on this list, please contact Sue Marone.

Cedars-Sinai in the News

Woman Donates Kidney to Twin Sister in a Rare Transplant That Doesn’t Require Anti-Rejection Drugs | CNN Online, Spectrum News 1, CBS News, and Las Vegas Review Journal
Irene Kim, MD 

George Berci | The Lancet
George Berci, MD 

Hypertension is a ‘Silent Killer.’ Here’s What Your Blood Pressure Should be at Every Age | Fortune
Joseph Ebinger, MD 

Crohn’s Disease is a Lifelong Condition, But Proper Treatment Makes all the Difference | USA Today
Gil Melmed, MD 

Heart Health Risks Spike During Pregnancy, Postpartum | Spectrum News 1
Janet Wei, MD 

Stroke Guidelines Updated, With Focus on Women and GLP-1s | HealthDay
Alexis Simpkins, MD, PhD; Shlee Song, MD 

Navigating Thanksgiving With Heart Disease: What to Eat and What to Avoid | Fox News
Sam Setareh, MD 

What to Know About Aortic Valve Disease | HealthCentral
Pedro Catarino, MD 

Faith Over Fear: How an Infant’s Family Treated her Sickle Cell Disease | BlackDoctor
Nicole Baca, MD

Faculty Publications

Biomedical Sciences

An Insight to PDAC Tumor Heterogeneity Across Pancreatic Subregions Using Computed Tomography Images. Javed, Sehrish, Touseef Ahmad Qureshi, Lixia Wang, Linda Azab, Srinivas Gaddam, Stephen J. Pandol, and Debiao Li. Frontiers in Oncology 14: 1378691.

Expression of Network Medicine-Predicted Genes in Human Macrophages Infected With Leishmania Major. Caixeta, Felipe, Vinicius Dantas Martins, Amanda Braga Figueiredo, Luis Carlos Crocco Afonso, Paolo Tieri, Filippo Castiglione, Leandro Martins de Freitas, and Tatiani Uceli Maioli. International Journal of Molecular Sciences 25 (22): 12084.

Cannabigerol (CBG): A Comprehensive Review of Its Molecular Mechanisms and Therapeutic Potential. Li, Shijia, Weini Li, Naseeb Kaur Malhi, Junwei Huang, Quanqi Li, Ziwei Zhou, Ruiheng Wang, Jiangling Peng, Tong Yin, and Honggen Wang. Molecules (Basel, Switzerland) 29 (22): 5471.

Inhibition of the E3 Ligase UBR5 Stabilizes TERT and Protects Vascular Organoids From Oxidative Stress. Zhao, Haijing, Nian Cao, Qi Liu, Yingyue Zhang, Rui Jin, Huiying Lai, Li Zheng, Honghong Zhang, Yue Zhu, Yuhan Ma, Zengao Yang, Zhengfeng Wu, Weini Li, Yuqi Liu, Long Cheng, and Yundai Chen. Journal of Translational Medicine 22 (1): 1080.

Longitudinal Quantitative MRI Provides Responsive Outcome Measures for Early and Late Muscle Changes in ALS. Diaz, Frank, John S. Thornton, Stephen S. Wastling, Abeer Asaab, Jasper M. Morrow, Nick Zafeiropoulos, Catherine Bresee, Peggy Allred, Pablo Avalos, Richard A. Lewis, Robert H. Baloh, and Clive N. Svendsen. Muscle & Nerve, November.

Top 2024 Images in Cardiothoracic Imaging. Mastrodicasa, Domenico, Suvai Gunasekaran, Samer Alabed, Kate Hanneman, and Gaurav S. Gulsin. Radiology. Cardiothoracic Imaging 6 (6): e240415.

Cardiology

Noninvasive Pulsed Radiofrequency for Trigeminal Neuralgia: Off the Beaten Path - Case Series. Mitra, Sukanya, Prateek Upadhyay, Jasveer Singh, and Prashant Ahlawat. Saudi Journal of Anaesthesia 18 (4): 569–72.

Balloon-Expandable vs Self-Expanding Valves for Transcatheter Treatment of Sievers Type 1 Bicuspid Aortic Stenosis. Buono, Andrea, Andrea Zito, Won-Keun Kim, Tommaso Fabris, Chiara De Biase, Michele Bellamoli, Nicholas Montarello, Giuliano Costa, Mesfer Alfadhel, Ofir Koren, Simone Fezzi, Barbara Bellini, Giuseppe Tarantini, et al. JACC. Cardiovascular Interventions, September, S1936-8798(24)01028-8.

Choice of End Points in Heart Failure Trials-Cause-Specific or All-Cause or Both? Kaul, Sanjay. JAMA Network Open 7 (11): e2446679.

Donor Selection for Heart Transplantation in 2024. Jain, Rashmi, Evan P. Kransdorf, Jennifer Cowger, Valluvan Jeevanandam, and Jon A. Kobashigawa. JACC. Heart Failure, November, S2213-1779(24)00732-7.

Adding AI to the Toolkit for Patients With Implantable Cardioverter-Defibrillators. Ramireddy, Archana, Eric D. Braunstein, and Sumeet S. Chugh. Journal of the American College of Cardiology, November, S0735-1097(24)09962-5.

Implications of Tricuspid Regurgitation Severity in Patients Undergoing Mitral Transcatheter Edge-to-Edge Repair. Shechter, Alon, Homa Taheri, Takashi Nagasaka, Aakriti Gupta, Danon Kaewkes, Vivek Patel, Kazuki Suruga, Manvir Dhillon, Keita Koseki, Ofir Koren, Moody Makar, Sabah Skaf, Dhairya Patel, Tarun Chakravarty, Robert J. Siegel, and Raj R. Makkar. Journal of the American Heart Association, November, e037635.

Transcatheter Tricuspid Valve Replacement. Hausleiter, Jörg, Lukas Stolz, Philipp Lurz, Volker Rudolph, Rebecca Hahn, Rodrigo Estévez-Loureiro, Charles Davidson, Firas Zahr, Susheel Kodali, Raj Makkar, Anson Cheung, Renato D. Lopes, Francesco Maisano, Neil Fam, Azeem Latib, Stephan Windecker, and Fabien Praz. Journal of the American College of Cardiology, November, S0735-1097(24)09961-3.

Coccidioidomycosis Transmission Through Solid Organ Transplantation (2013-2022): A Report of the Organ Procurement and Transplantation Network Ad Hoc Disease Transmission Advisory Committee. Lee, Dong Heun, Maheen Z. Abidi, Cynthia Fisher, Anna L. Hughart, Mitsuru Toda, Samantha Williams, Gerald J. Berry, Riki Graves, Dzhuliyana Handarova, Chak-Sum Ho, Michelle Kittleson, Marilyn E. Levi, Taylor Livelli, Charles C. Marboe, Pallavi Annamabhotla, Rachel A. Miller, Tanvi Sharma, Marty T. Sellers, Sarah Taimur, Helen S. Te, Anil J. Trindade, R. Patrick Wood, Lorenzo Zaffiri, Stephanie M. Pouch, and Lara Danziger-Isakov. Transplant Infectious Disease, November, e14406.

Enhanced Parkin-Mediated Mitophagy Mitigates Adverse Left Ventricular Remodelling After Myocardial Infarction: Role of PR-364. Ai, Lizhuo, Juliana de Freitas Germano, Chengqun Huang, Marianne Aniag, Savannah Sawaged, Jon Sin, Reetu Thakur, Deepika Rai, Christopher Rainville, David E. Sterner, Yang Song, Honit Piplani, Suresh Kumar, Tauseef R. Butt, Robert M. Mentzer, Aleksandr Stotland, Roberta A. Gottlieb, and Jennifer E. Van Eyk. European Heart Journal, November, ehae782.

Enrollment of Females in Randomized Trials for Glucagon-Like Peptide 1 Receptor Agonists: A Systematic Review. Rivera, Frederick Berro, Mc John Caro Ybañez, John Vincent Magalong, Mario Prado, Eloise Arias Aguirre, Ana Patricia Ting Cañares, Janos Marc Rubia, Allyn Ralph Hiyas, Polyn Luz S. Pine, Kyla Lara-Breitinger, Francisco Lopez-Jimenez, and Martha Gulati. JACC. Advances 3 (12): 101386.

Interplay Between Lifestyle Factors and Polygenic Risk for Incident Coronary Heart Disease in a Large Multiethnic Cohort. Iribarren, Carlos, Meng Lu, Martha Gulati, Nathan D. Wong, Roberto Elosua, and Jamal S. Rana. International Journal of Cardiology. Cardiovascular Risk and Prevention 23 (December): 200350.

Age-Based Lifestyle Patterns in Patients With Acute Myocardial Infarction. Tsuji, Masaki, and Shun Minatsuki. International Heart Journal 65 (6): 967–68.

SOPRANO: Macitentan in Patients With Pulmonary Hypertension Following Left Ventricular Assist Device Implantation. Frantz, Robert P., Shashank S. Desai, Gregory Ewald, Veronica Franco, Antoine Hage, Evelyn M. Horn, Shane J. LaRue, Michael A. Mathier, Stacy Mandras, Myung H. Park, Ashwin K. Ravichandran, Joel D. Schilling, I.-Wen Wang, Ronald Zolty, Gabriela Gomez Rendon, Mark A. Rocco, Mona Selej, Carol Zhao, and J. Eduardo Rame. Pulmonary Circulation 14 (4): e12446.

Utility of Mechanistic Target of Rapamycin Inhibitors in Cardiac Sarcoidosis. Richards, Donald, Hidesato Fujito, Aakash Shanbhag, Bobak Akhavan, Elizabeth Frame, Sean Hayes, John Friedman, Louise Thomson, Piotr Slomka, Daniel Berman, and Evan P. Kransdorf. Journal of Cardiac Failure, November, S1071-9164(24)00929-1.

Artificial Intelligence and Digital Tools for Design and Execution of Cardiovascular Clinical Trials. Hu, Jiun-Ruey, John R. Power, Faiez Zannad, and Carolyn S. P. Lam. European Heart Journal, November, ehae794.

Describing Cardiac Anatomy: The Truth Is Staring Us in the Face. Richardson, Travis D., Zachi Itzhak Attia, Ehud Chorin, Mario Delmar, Luigi Di Biase, Kenneth A. Ellenbogen, Sabine Ernst, Michael H. Gollob, Julia H. Indik, Prince J. Kannankeril, Raphael Rosso, Pasquale Santangeli, Kyoko Soejima, William G. Stevenson, Charles D. Swerdlow, Roderick Tung, Pugazhendhi Vijayaraman, Arthur A. M. Wilde, Douglas P. Zipes, and Sami Viskin. Heart Rhythm 21 (12): 2386–87.

Mechanical Loading Reveals an Intrinsic Cardiomyocyte Stiffness Contribution to Diastolic Dysfunction in Murine Cardiometabolic Disease. Janssens, Johannes V., Antonia J. A. Raaijmakers, Parisa Koutsifeli, Kate L. Weeks, James R. Bell, Jennifer E. Van Eyk, Claire L. Curl, Kimberley M. Mellor, and Lea M. D. Delbridge. The Journal of Physiology, December.

On-Treatment Change in d-Dimer Is Associated With Differential Outcomes Among Therapeutic Dose Heparin-Treated Noncritically Ill Patients Hospitalized for COVID-19. Wahid, Lana, Joshua Froess, Thomas L. Ortel, Ryan Zarychanski, Jeffrey S. Berger, Mary Cushman, Derek C. Angus, Valerie Renard, Parisa Farahani, Steve A. Webb, Anna Heath, Lucas C. Godoy, Michael E. Farkouh, Judith S. Hochman, Matthew D. Neal, and Patrick R. Lawler. Arteriosclerosis, Thrombosis, and Vascular Biology, December.

Computational Biomedicine

Integrating Prior Knowledge Using Transformer for Gene Regulatory Network Inference. Weng, Guangzheng, Patrick Martin, Hyobin Kim, and Kyoung Jae Won. Advanced Science (Weinheim, Baden-Wurttemberg, Germany), November, e2409990.

Evaluating Bias-Mitigated Predictive Models of Perinatal Mood and Anxiety Disorders. Wong, Emily F., Anil K. Saini, Eynav E. Accortt, Melissa S. Wong, Jason H. Moore, and Tiffani J. Bright. JAMA Network Open 7 (12): e2438152.

Imaging

Malignant Bone-Forming Neoplasm With NIPBL::BEND2 Fusion. Dashti, Nooshin K., George Matcuk, Abbas Agaimy, Carla Saoud, and Cristina R. Antonescu. Genes, Chromosomes & Cancer 63 (11): e70015.

Diagnostic Performance of Dual-Energy Computed Tomography in Detecting Anterior Cruciate Ligament Injuries: A Systematic Review and Meta-Analysis. Valizadeh, Parya, Payam Jannatdoust, Mohammad-Taha Pahlevan-Fallahy, Sara Bagherieh, Paniz Adli, Melika Amoukhteh, Amir Hassankhani, George R. Matcuk, and Ali Gholamrezanezhad. Skeletal Radiology, November.

Medicine

Fusobacterium Nucleatum Abundance is Associated with Cachexia in Colorectal Cancer Patients: The ColoCare Study. Ilozumba, Mmadili N., Tengda Lin, Sheetal Hardikar, Doratha A. Byrd, June L. Round, W. Zac Stephens, Andreana N. Holowatyj, Christy A. Warby, Victoria Damerell, Christopher I. Li, Jane C. Figueiredo, Adetunji T. Toriola, David Shibata, Gary C. Fillmore, Bartley Pickron, Erin M. Siegel, Christoph Kahlert, Vaia Florou, Biljana Gigic, Jennifer Ose, and Cornelia M. Ulrich. Cancer Medicine 13 (22): e70431.

Characteristics and Treatment Patterns of Long-Surviving Patients with Multiple Myeloma: Over 13 Years of Follow-up in the ConnectⓇ MM Registry. Terebelo, Howard R., James Omel, Lynne I. Wagner, James W. Hardin, Robert M. Rifkin, Sikander Ailawadhi, Brian G. M. Durie, Mohit Narang, Kathleen Toomey, Cristina J. Gasparetto, Prashant Joshi, Edward Yu, E. Dawn Flick, Ying-Ming Jou, Hans C. Lee, Rafat Abonour, and Sundar Jagannath. Clinical Lymphoma, Myeloma & Leukemia, November, S2152-2650(24)02401-7.

Associations Between Dietary Patterns and Quality of Life in a Longitudinal Cohort of Colorectal Cancer Survivors. Smith, Kristen S., Lisa M. Gudenkauf, Aasha I. Hoogland, Xiaoyin Li, Rachel Hoobler, Mary C. Playdon, Biljana Gigic, Brent J. Small, Brian D. Gonzalez, Laura B. Oswald, Doratha A. Byrd, K. Leigh Greathouse, Cornelia M. Ulrich, Christopher I. Li, David Shibata, Adetunji T. Toriola, Anita R. Peoples, Erin M. Siegel, Jane C. Figueiredo, Heather S. L. Jim, and Sylvia L. Crowder. Nutrients 16 (22): 3860.

Insights From Team Clinic: A Person-Centered Virtual Peer Group Care Model Adapted for Marginalized and Historically Excluded Youth With Type 1 Diabetes (T1D). Flores Garcia, Jaquelin, Mark W. Reid, Alejandra Torres Sanchez, Valerie Ruelas, Sarah-Jeanne Salvy, Alex Thomas, Gary Ashwal, D. Steven Fox, and Jennifer K. Raymond. Children (Basel, Switzerland) 11 (11): 1383.

The Burden of Alcohol and Substance Use Disorders in Adolescents and Young Adults. Danpanichkul, Pojsakorn, Kwanjit Duangsonk, Luis Antonio Díaz, Vincent L. Chen, Pooja Rangan, Banthoon Sukphutanan, Priyata Dutta, Ornpailin Wanichthanaolan, Vijay Ramadoss, Benedix Sim, Daniel Tung, Noppachai Siranart, Hidenao Noritake, Hirokazu Takahashi, Mazen Noureddin, Lorenzo Leggio, Ju Dong Yang, Michael B. Fallon, Juan Pablo Arab, Gerald Scott Winder, Suthat Liangpunsakul, Jessica Leigh Mellinger, and Karn Wijarnpreecha. Drug and Alcohol Dependence 266 (November): 112495.

Alcohol-Related Liver and Extrahepatic Malignancies: Burden of Disease and Socioeconomic Disparities in 2019. Danpanichkul, Pojsakorn, Kanokphong Suparan, Nathorn Chaiyakunapruk, Thanida Auttapracha, Siwanart Kongarin, Phuuwadith Wattanachayakul, Vijay Ramadoss, Thanathip Suenghataiphorn, Banthoon Sukphutanan, Yanfang Pang, Rashid N. Lui, Ju Dong Yang, Mazen Noureddin, Luis Antonio Díaz, Suthat Liangpunsakul, Juan Pablo Arab, and Karn Wijarnpreecha. European Journal of Gastroenterology & Hepatology, November.

Development of a Core Outcome Set for Recurrent Acute and Chronic Pancreatitis: Results of a Delphi Poll. Rahib, Lola, William Salerno, Maisam Abu-El-Haija, Darwin L. Conwell, A. Jay Freeman, Phil A. Hart, Stephen J. Pandol, Emily R. Perito, Dhiraj Yadav, and Tonya M. Palermo. Pancreatology, November, S1424-3903(24)00798-1.

Older Age But Not Comorbidity is Associated With Worse Survival in Patients With Hepatocellular Carcinoma. Kanneganti, Mounika, Mohammed Al-Hasan, Samantha Bourque, Sneha Deodhar, Ju Dong Yang, Daniel Q. Huang, Anand V. Kulkarni, Purva Gopal, Neehar D. Parikh, Fasiha Kanwal, Madhukar S. Patel, and Amit G. Singal. Clinical Gastroenterology and Hepatology, November, S1542-3565(24)01038-3.

Tumor Upstaging in Invasive Melanoma Is Associated With Changes in Clinical Management and Worse Prognosis. Rosenthal, Amanda, Joyce Y. Kim, Margit Lw Juhasz, Geena Conde, Clare Chen, Sarah Eng, Cristo A. Carrasco Mendoza, Crystal T. Chang, Iesha Ticknor, Leandra Doan, Kathyrn B. Schwarzmann, Sarah Garzione, Yunjie Li, Zeuz A. Islas, Nima M. Gharavi, and Jeremy R. Man. Journal of the American Academy of Dermatology, November, S0190-9622(24)03233-X.

Polyploid Cancer Cells Reveal Signatures of Chemotherapy Resistance. Schmidt, Michael J., Amin Naghdloo, Rishvanth K. Prabakar, Mohamed Kamal, Radu Cadaneanu, Isla P. Garraway, Michael Lewis, Ana Aparicio, Amado Zurita-Saavedra, Paul Corn, Peter Kuhn, Kenneth J. Pienta, Sarah R. Amend, and James Hicks. Oncogene, November.

A Broader Outlook Is Required to Stage and Classify Pituitary Neoplasms for Patient Care. Melmed, Shlomo, Maria Fleseriu, John A. H. Wass, and Ken K. Y. Ho. Brain Pathology (Zurich, Switzerland), November, e13321.

Clinical Management Update of Oral Leukoplakia: A Review From the American Head and Neck Society Cancer Prevention Service. Gates, James C., Marianne Abouyared, Yelizaveta Shnayder, D. Gregory Farwell, Andrew Day, Faizan Alawi, Michael Moore, Andrew J. Holcomb, Andrew Birkeland, and Joel Epstein. Head & Neck, November.

Guidelines for the Correct Use of the Nomenclature of Biochemical Indices of Bone Status: A Position Statement of the Joint IOF Working Group and IFCC Committee on Bone Metabolism. Lombardi, Giovanni, Niklas Rye Jørgensen, Nicholas C. Harvey, Eugene V. McCloskey, Kristina E. Åkesson, Richard Eastell, Patrick Garnero, John A. Kanis, Patricia Khashayar, Nancy E. Lane, Michael R. McClung, Stuart Silverman, Konstantinos Makris, Harjit Pal Bhattoa, Samuel D. Vasikaran, Richard Pikner, Etienne Cavalier, and Joint IOF Working Group and IFCC Committee on Bone Metabolism. Clinical Chemistry and Laboratory Medicine, November.

Implementation Facilitators and Barriers of Stress First Aid to Protect Mental Health of Frontline Health Care Workers During the COVID-19 Pandemic: A Qualitative Study. Huilgol, Shreya S., Lu Dong, Nabeel Qureshi, Kathryn Bouskill, Lisa S. Meredith, and Courtney Gidengil. BMC Health Services Research 24 (1): 1475.

Longitudinal Body Composition Identifies Hepatocellular Carcinoma With Cachexia Following Combined Immunotherapy and Target Therapy (CHANCE2213). Jin, Zhi-Cheng, Jia-Wei Zhou, Jian-Jian Chen, Rong Ding, Bernhard Scheiner, Si-Na Wang, Hai-Liang Li, Qing-Xia Shen, Qing-Yun Lu, Yi Liu, Wei-Hua Zhang, Biao Luo, Hai-Bin Shi, Ming Huang, Ye-Ming Wu, Chun-Wang Yuan, Ming-Sheng Huang, Jia-Ping Li, Jian-Bing Wu, Xiao-Li Zhu, Bin-Yan Zhong, Hai-Feng Zhou, Yu-Qing Wang, Shan-Zhi Gu, Zhi-Yi Peng, Chuan-Sheng Zheng, Rui-Bao Liu, Guo-Hui Xu, Wei-Zhu Yang, Ai-Bing Xu, Dong-Fang Liu, Xiaolong Qi, Yee Hui Yeo, Hai-Dong Zhu, Yang Zhao, David J. Pinato, Fanpu Ji, and Gao-Jun Teng. Journal of Cachexia, Sarcopenia and Muscle, November.

Relationship Between High-Resolution Computed Tomography Quantitative Imaging Analysis and Physiological and Clinical Features in Antisynthetase Syndrome-Related Interstitial Lung Disease. Bae, Sangmee Sharon, Fereidoun Abtin, Grace Kim, Daniela Markovic, Cato Chan, Siamak Moghadam-Kia, Chester V. Oddis, Daniel Sullivan, Galina Marder, Swamy Venuturupalli, Paul F. Dellaripa, Tracy J. Doyle, Gary Matt Hunninghake, Jeremy Falk, Christina Charles-Schoeman, Donald P. Tashkin, Jonathan Goldin, and Rohit Aggarwal. RMD Open 10 (4): e004592.

Liquid Biopsy in Hepatocellular Carcinoma: Challenges, Advances, and Clinical Implications. Park, Jaeho, Yi-Te Lee, Vatche G. Agopian, Jessica S. Liu, Ekaterina K. Koltsova, Sungyong You, Yazhen Zhu, Hsian-Rong Tseng, and Ju Dong Yang. Clinical and Molecular Hepatology, November.

Metabolites Link Intake of a Healthy Diet to Better Insulin and Glucose Homeostasis in the Microbiome and Insulin Longitudinal Evaluation Study (MILES). Wood, Alexis C., Danielle J. Lee, Patricia A. Sheridan, Elizabeth T. Jensen, Gautam Ramesh, Alain G. Bertoni, Stephen S. Rich, Yii-Der I. Chen, David M. Herrington, Jerome I. Rotter, and Mark O. Goodarzi. Current Developments in Nutrition 8 (11): 104462.

Consensus Report on the Use of Continuous Glucose Monitoring in Chronic Kidney Disease and Diabetes. Rhee, Connie M., Roma Y. Gianchandani, David Kerr, Athena Philis-Tsimikas, Csaba P. Kovesdy, Robert C. Stanton, Andjela T. Drincic, Rodolfo J. Galindo, Kamyar Kalantar-Zadeh, Joshua J. Neumiller, Ian H. de Boer, Marcus Lind, Sun H. Kim, Alessandra T. Ayers, Cindy N. Ho, Rachel E. Aaron, Tiffany Tian, and David C. Klonoff. Journal of Diabetes Science and Technology, November, 19322968241292041.

Evaluating AI Proficiency in Nuclear Cardiology: Large Language Models Take on the Board Preparation Exam. Builoff, Valerie, Aakash Shanbhag, Robert Jh Miller, Damini Dey, Joanna X. Liang, Kathleen Flood, Jamieson M. Bourque, Panithaya Chareonthaitawee, Lawrence M. Phillips, and Piotr J. Slomka. Journal of Nuclear, November, 102089.

Multiple Myeloma Long-Term Survivors Exhibit Sustained Immune Alterations Decades After First-Line Therapy. Lutz, Raphael, Florian Grünschläger, Malte Simon, Mohamed H. S. Awwad, Marcus Bauer, Schayan Yousefian, Niklas Beumer, Lea Jopp-Saile, Anastasia Sedlmeier, Llorenç Solé-Boldo, Bogdan Avanesyan, Dominik Vonficht, Patrick Stelmach, Georg Steinbuss, Tobias Boch, Simon Steiger, Marc-Andrea Baertsch, Nina Prokoph, Karsten Rippe, Brian G. M. Durie, Claudia Wickenhauser, Andreas Trumpp, Carsten Müller-Tidow, Daniel Hübschmann, Niels Weinhold, Marc S. Raab, Benedikt Brors, Hartmut Goldschmidt, Charles D. Imbusch, Michael Hundemer, and Simon Haas. Nature Communications 15 (1): 10396.

Authors’ Reply to: Concerns Regarding ‘Development of a Machine Learning-Based Model to Predict Hepatic Inflammation in Chronic Hepatitis B Patients With Concurrent Hepatic Steatosis: A Cohort Study.’ Rui, Fajuan, Yee Hui Yeo, Xiaorong Tian, Yunliang Chen, and Jie Li. EClinicalMedicine 78 (December): 102908.

Fostamatinib for Hospitalized Adults With COVID-19 and Hypoxemia: A Randomized Clinical Trial. Collins, Sean P., Matthew S. Shotwell, Jeffrey R. Strich, Kevin W. Gibbs, Marjolein de Wit, D. Clark Files, Michelle Harkins, Kris Hudock, Lisa H. Merck, Ari Moskowitz, Krystle D. Apodaca, Aaron Barksdale, ACTIV-4 Host Tissue Investigators, et al. JAMA Network Open 7 (12): e2448215.

Anti-CdtB and Anti-Vinculin Antibodies to Diagnose Irritable Bowel Syndrome in Inflammatory Bowel Disease Patients. Barros, Luisa Leite, Gabriela Leite, Walter Morales, Gillian M. Barlow, Matheus Freitas Cardoso de Azevedo, Alexandre de Sousa Carlos, Adérson Omar Mourão Cintra Damião, Mark Pimentel, and Alberto Queiroz Farias. BMC Gastroenterology 24 (1): 448.

Implementing INTERACT in Veterans Health Administration Community Living Centers: A Pragmatic Randomized Trial. Mor, Vincent, Debra Saliba, Orna Intrator, Roee Gutman, Amy L. Mochel, Margaret Peg Baumann, Rebecca Boxer, Heather D’Adamo, Hiroshi Gotanda, Kim W. House, Seema Joshi, Linda Sohn, Arti Tayade, Kisa A. Hilliard, Ciaran S. Phibbs, and Joseph G. Ouslander. Journal of the American Geriatrics Society, December.

Respiratory Equality: Let’s Stop Playing Favorites With COVID-19 in the Healthcare Setting. Passaretti, Catherine L., Werner Bischoff, Justin Chan, Daniel J. Diekema, Shira Doron, Carolee Estelle, Jesse T. Jacob, Tsun Sheng N. Ku, Surbhi Leekha, Richard A. Martinello, Vidya K. Mony, L. Silvia Munoz-Price, Rekha Murthy, Judith A. O’Donnell, David H. Priest, Mindy M. Sampson, Thomas J. Sandora, Graham M. Snyder, Michael P. Stevens, Julie E. Szymczak, Francesca Torriani, Deborah S. Yokoe, and Jonas Marschall. Infection Control and Hospital Epidemiology, December, 1–2.

Evolving Trends in Epidemiology, Etiology, and Treatment Patterns for Hepatocellular Carcinoma in South Korea. Hwang, Soo Young, and Ju Dong Yang. Journal of Liver Cancer, December.

Neurology

Incorporation of the Central Vein Sign Into the McDonald Criteria. Amin, Moein, Kunio Nakamura, Lynn Daboul, Carly O’Donnell, Quy Cao, Paulo Rodrigues, John Derbyshire, Christina Azevedo, Amit Bar-Or, Eduardo Caverzasi, Peter A. Calabresi, Bruce A. C. Cree, Leorah Freeman, Roland Henry, Erin E. Longbrake, Jiwon Oh, Nico Papinutto, Daniel Pelletier, Vesna Prčkovska, Praneeta C. Raza, Marc Ramos, Rohini Samudralwar, Matthew Schindler, Elias S. Sotirchos, Nancy Sicotte, Andrew J. Solomon, Russell Shinohara, Daniel S. Reich, Pascal Sati, and Daniel Ontaneda. Multiple Sclerosis and Related Disorders 93 (November): 106182.

Neurosurgery

Vascular Endothelial Growth Factor and the Pathogenesis of Intracranial Aneurysms: A Systematic Review on the Missing Link in a Complex Pathway. Nisson, Peyton L., Michael T. Lawton, Oscar Cisneros, Takuma Maeda, Nestor R. Gonzalez, Juhana Frösen, and Tomoki Hashimoto. Journal of the American Heart Association, November, e035638.

Endovascular Therapy Versus Medical Management in Isolated Anterior Cerebral Artery Acute Ischemic Stroke: A Multinational Multicenter Propensity Score-Weighted Study. Salim, Hamza Adel, Benjamin Pulli, Vivek Yedavalli, Fathi Milhem, Basel Musmar, Nimer Adeeb, Dhairya A. Lakhani, Muhammed Amir Essibayi, Jeremy Josef Heit, Tobias D. Faizy, Kareem El Naamani, Nils Henninger, MAD-MT Investigators, et al. Journal of Neurointerventional Surgery, November, jnis-2024-022467.

The Value of a Neurosurgeon: Is Neurosurgical Compensation Proportional to Value Added? A Systematic Review of the Literature and an Update on a Changing Healthcare Economy. Hopkins, Benjamin S., Jonathan Dallas, Gage Guerra, Hayden L. Hofmann, Matthew Ordon, Vincent N. Nguyen, Bassir Caravan, John Liu, Gabriel Zada, and William J. Mack. Journal of Neurosurgery, November, 1–13.

Domain-Specific Representation of Social Inference by Neurons in the Human Amygdala and Hippocampus. Cao, Runnan, Julien Dubois, Adam N. Mamelak, Ralph Adolphs, Shuo Wang, and Ueli Rutishauser. Science Advances 10 (49): eado6166.

OBGYN

Variability in Perinatal Sleep Quality Is Associated With an Atypical Cortisol Awakening Response and Increased Mood Symptoms. Okun, Michele L., Suzanne Segerstrom, Susan Jackman, Kharah Ross, Christine Dunkel Schetter, and Mary Coussons-Read. Psychoneuroendocrinology 172 (November): 107248.

The Impact of Exclusively Virtual Preoperative Evaluation on Complications of Gynecologic Surgery. Schneyer, Rebecca J., Raanan Meyer, Kacey M. Hamilton, Mireille D. Truong, Kelly N. Wright, and Matthew T. Siedhoff. Journal of Minimally Invasive Gynecology, November, S1553-4650(24)01532-2.

The Impact of Minimally Invasive Gynecologic Surgery Subspecialty Training on Outcomes of Myomectomy: A Retrospective Cohort Study. Schneyer, Rebecca J., Raanan Meyer, Margot L. Barker, Kacey M. Hamilton, Matthew T. Siedhoff, Mireille D. Truong, and Kelly N. Wright. Journal of Minimally Invasive Gynecology, December, S1553-4650(24)01533-4.

Orthopaedics

Have We Made Advancements in Optimizing Surgical Outcomes and Enhancing Recovery for Patients with High-Risk Adult Spinal Deformity Over Time? Passias, Peter G., Lara Passfall, Peter S. Tretiakov, Ankita Das, Oluwatobi O. Onafowokan, Justin S. Smith, Virginie Lafage, Renaud Lafage, Breton Line, Jeffrey Gum, Khaled M. Kebaish, Khoi D. Than, Gregory Mundis, Richard Hostin, Munish Gupta, Robert K. Eastlack, Dean Chou, Alexa Forman, Bassel Diebo, Alan H. Daniels, Themistocles Protopsaltis, D. Kojo Hamilton, Alex Soroceanu, Raymarla Pinteric, Praveen Mummaneni, Han Jo Kim, Neel Anand, Christopher P. Ames, Robert Hart, Douglas Burton, Frank J. Schwab, Christopher Shaffrey, Eric O. Klineberg, Shay Bess, and International Spine Study Group. Operative Neurosurgery (Hagerstown, Md.), November.

Machine Learning Algorithms Exceed Comorbidity Indices in Prediction of Short-Term Complications After Hip Fracture Surgery. Gowd, Anirudh K., Edward C. Beck, Avinesh Agarwalla, Dev M. Patel, Ryan C. Godwin, Brian R. Waterman, Milton T. Little, and Joseph N. Liu. The Journal of the American Academy of Orthopaedic Surgeons, November.

When is Staging Complex Adult Spinal Deformity Advantageous? Identifying Subsets of Patients Who Benefit From Staged Interventions. Passias, Peter G., Peter Tretiakov, Oluwatobi O. Onafowokan, Ankita Das, Renaud Lafage, Justin S. Smith, Breton G. Line, Pratibha Nayak, Bassel Diebo, Alan H. Daniels, Jeffrey L. Gum, D. Kojo Hamilton, Thomas J. Buell, Alex Soroceanu, Justin K. Scheer, Robert K. Eastlack, Jeffrey P. Mullin, Andrew J. Schoenfeld, Gregory M. Mundis, Naobumi Hosogane, Mitsuru Yagi, Praveen V. Mummaneni, Dean Chou, Kai-Ming Fu, Khoi D. Than, Neel Anand, David O. Okonkwo, Michael Y. Wang, Eric Klineberg, Khaled M. Kebaish, Stephen Lewis, Richard Hostin, Munish Gupta, Lawrence Lenke, Han Jo Kim, Christopher P. Ames, Christopher I. Shaffrey, Shay Bess, Frank Schwab, Virginie Lafage, and Douglas Burton. Journal of Neurosurgery. Spine, November, 1–8.

The Utility of Surgical Drains in Adult and Pediatric Posterior Spinal Fusion: Systematic Review and Meta-Analysis. Pivazyan, Gnel, Carlynn G. Winters, Jean-Paul Bryant, Ziam Khan, Kelsey D. Cobourn, David L. Skaggs, Jean-Marc Voyadzis, Mani N. Nair, and Faheem A. Sandhu. Neurosurgical Review 47 (1): 873.

The 2024 American Orthopaedic Association-Japanese Orthopaedic Association Traveling Fellowship. McDonald, Lucas S., Kelly K. Hynes, Joshua A. Parry, Byron F. Stephens, and Joseph H. Schwab. The Journal of Bone and Joint Surgery. American Volume, November.

Pathology and Laboratory Medicine

Gastritis: Pathophysiology and Clinical Management. Fansiwala, Kush, Michael S. Lewis, and Joseph R. Pisegna. The American Journal of Gastroenterology, November.

Clinicopathologic Findings in a Cohort of Metastases to the Stomach. Toussieng, Trevor, Brent K. Larson, Miguel Burch, Alexandra Gangi, Jun Gong, Maha Guindi, Michael Kozak, Keith Lai, Danielle A. Hutchings, and Kevin M. Waters. Human Pathology 154 (November): 105694.

Insights to Aging Prediction With AI Based Epigenetic Clocks. Levy, Joshua J., Alos B. Diallo, Marietta K. Saldias Montivero, Sameer Gabbita, Lucas A. Salas, and Brock C. Christensen. Epigenomics, November, 1–9.

Genomic Landscape of Testicular Follicular Lymphoma Is Characterized by Frequent 1p36/TNFRSF14 Alterations. Zhang, Weiwei, Anamarija M. Perry, Hans Magne Hamnvåg, Sumire Kitahara, Sarah L. Ondrejka, Alexandra E. Kovach, Ji Jane Yuan, Krystie Chew, Julia Hsueh Davidson, Victoria Bedell, Jamie Stokke, and Joo Y. Song. Blood Advances, November, bloodadvances.2024014002.

Fibrillary Glomerulonephritis Associated With Hashimoto’s Thyroiditis. Dao, Kevin T., Arian Ashrafi, Matthew Palmbach, Tanya Eftekhari, Erfan Fallahtafti, Cynthia C. Nast, and Sabitha Eppanapally. Cureus 16 (10): e72736.

Pediatrics

A Computable Phenotype Algorithm for Postvaccination Myocarditis/Pericarditis Detection Using Real-World Data: Validation Study. Deady, Matthew, Raymond Duncan, Matthew Sonesen, Renier Estiandan, Kelly Stimpert, Sylvia Cho, Jeffrey Beers, Brian Goodness, Lance Daniel Jones, Richard Forshee, Steven A. Anderson, and Hussein Ezzeldin. Journal of Medical Internet Research 26 (November): e54597.

Mapping Genes for Human Face Shape: Exploration of Univariate Phenotyping Strategies. Yuan, Meng, Seppe Goovaerts, Michiel Vanneste, Harold Matthews, Hanne Hoskens, Stephen Richmond, Ophir D. Klein, Richard A. Spritz, Benedikt Hallgrimsson, Susan Walsh, Mark D. Shriver, John R. Shaffer, Seth M. Weinberg, Hilde Peeters, and Peter Claes. PLoS Computational Biology 20 (12): e1012617.

Syndrome-Informed Phenotyping Identifies a Polygenic Background for Achondroplasia-like Facial Variation in the General Population. Vanneste, Michiel, Hanne Hoskens, Seppe Goovaerts, Harold Matthews, Jay Devine, Jose D. Aponte, Joanne Cole, Mark Shriver, Mary L. Marazita, Seth M. Weinberg, Susan Walsh, Stephen Richmond, Ophir D. Klein, Richard A. Spritz, Hilde Peeters, Benedikt Hallgrímsson, and Peter Claes. Nature Communications 15 (1): 10458.

Radiation Oncology

Pembrolizumab for Locally Advanced Cervical Cancer. Kamrava, Mitchell, and Sushil Beriwal. Lancet (London, England) 404 (10467): 2049.

Surgery

2024 Canadian Surgery Forum: Sept. 25-28, 2024. Li, Christine, Michael Guo, Ahmer Karimuddin, Michael Guo, Christine Li, Ahmer Karimuddin, Jason Sutherland, Bright Huo, Tyler McKechnie, Monica Ortenzi, Yung Lee, Stavros Antoniou, Andrew Beckett, et al. Canadian Journal of Surgery. Journal Canadien De Chirurgie 67 (6suppl2): S77–108.

A 2-Stage 6 Toe-to-Hand Transfer for the Reconstruction of Bilateral Digitless Hands. Lefebvre, Rachel, Sofia Bougioukli, Meghan McCullough, John Kelpin, Ed Detels, and Milan Stevanovic. Hand (New York, N.Y.), November, 15589447241293164.

Therapeutic Outcomes in 691 Angiosarcomas of the Head and Neck-A Retrospective SEER Study. Knoedler, Leonard, Cosima C. Hoch, Helena Baecher, Benedikt Geldner, Tobias Niederegger, Samuel Knoedler, Alexandre G. Lellouch, Max Heiland, Steffen Koerdt, and Michael Alfertshofer. The Journal of Craniofacial Surgery, November.

Reversal of Endocrine Resistance via N6AMT1-NEDD4L Pathway-Mediated P110α Degradation. Ji, Likeng, Jiongyu Chen, Lifang He, Fan Zhang, Zihao Deng, Jiediao Lin, Zhaochang Qi, Xi Luo, Armando E. Giuliano, Xiaojiang Cui, Stanley Li Lin, and Yukun Cui. Oncogene, December.

Has the Use of Enhanced Recovery Protocols in Colorectal Surgery Increased Postoperative Bleeding Complications? Aviran, Eyal, Dan Assaf, Karen Zaghiyan, and Phillip Fleshner. Diseases of the Colon and Rectum, December.

Best Practices for Delivering Neoadjuvant Therapy in Pancreatic Ductal Adenocarcinoma. Cloyd, Jordan M., Angela Sarna, Matthew J. Arango, Susan E. Bates, Manoop S. Bhutani, Mark Bloomston, Vincent Chung, Efrat Dotan, Cristina R. Ferrone, Patricia F. Gambino, Ajit H. Goenka, Karyn A. Goodman, William A. Hall, Jin He, Melissa E. Hogg, Shiva Jayaraman, Avinash Kambadakone, Matthew H. G. Katz, Alok A. Khorana, Andrew H. Ko, Eugene J. Koay, David A. Kooby, Somashekar G. Krishna, Liliana K. Larsson, Richard T. Lee, Anirban Maitra, Nader N. Massarweh, Sameh Mikhail, Mahvish Muzaffar, Eileen M. O’Reilly, Manisha Palta, Maria Q. B. Petzel, Philip A. Philip, Marsha Reyngold, Daniel Santa Mina, Davendra P. S. Sohal, Tilak K. Sundaresan, Susan Tsai, Kea L. Turner, Timothy J. Vreeland, Steve Walston, M. Kay Washington, Terence M. Williams, Jennifer Y. Wo, and Rebecca A. Snyder. JAMA Surgery, December.

Outcomes for Patients With Obesity Undergoing Adrenalectomy for Pheochromocytoma: An International Multicenter Analysis. Verhoeff, Kevin, Alessandro Parente, Yanbo Wang, Nanya Wang, Zhicheng Wang, Maciej Śledziński, Andrzej Hellmann, Marco Raffaelli, Francesco Pennestrì, Mark Sywak, Alexander J. Papachristos, Fausto F. Palazzo, International Pheo Study Group, et al. Annals of Surgical Oncology, December.

Return on Investment With Health Care Simulation. Metcalfe-Smith, Russell D. Nursing Administration Quarterly 49 (1): 44–50.