Faculty Publications March 5-12

This week’s edition of Faculty Publications includes Cedars-Sinai studies that were published March 5-12. If you have a published paper from this period that does not appear on this list, please contact Sue Marone.

Editor’s note: Faculty Publications will not publish on March 20, but will resume on March 27. Studies published March 12-26 will appear in that edition.

Cedars-Sinai in the News

Is This Treadmill Walking Trend Good for Your Fitness? | The New York Times
Eli Friedman, MD

Five Types of Cancer are Surging Worldwide—How to Lower Your Risk | Newsweek
Ju Dong Yang, MD

6 Subtle Signs of Joint Inflammation, According to Doctors | Prevention
David Kruse, MD

This Overlooked Type of Stress May be Far Worse for Your Physical Health Than You Think | HuffPost
Jace Reed, MD

Biological Aging Happens in Bursts. Here's When and How to Prepare | SELF
Bert Mandelbaum, MD

Inside GI’s ‘Endoscopy 3.0’ Revolution | Becker’s ASC Review
Barham Abu Dayyeh, MD, MPH

Ozempic, Wegovy may Help Reverse Damage Caused by Osteoarthritis | Healthline
Bert Mandelbaum, MD

Cedars-Sinai Researchers Create New AI-Based System to Read Echocardiograms | Spectrum News 1
David Ouyang, MD 

Faculty Publications

Anesthesiology

Precision Anesthesia and Pharmacogenomics: A Scoping Review of Personalized Drug Response. Nikzad, Sarina, Ofelia Loani Elvir-Lazo, and Robert Wong. Frontiers in Anesthesiology 5 (January).

Real-Time Flow-Pressure Coupling Under Pulse Contour Monitoring in Kidney Transplantation: Prospective Algorithm and Retrospective Phenotype Assignment. Cutler, Jennifer, Leon Wang, Hooman Golfeiz, Eric McDaniel, Ryan Barnette, Wesley Glick, Avner Gereboff, Leah Breen, Blake Simon, and Robert Kariger. Journal of Clinical Monitoring and Computing, March.

Biomedical Sciences

Dynamic Transcriptomic Remodeling in Grafted Human Neural Progenitor Cells Uncovers Mechanisms for Vision Preservation in a Rat Model of Retinitis Pigmentosa. Shahin, Saba, Shaughn Bell, Bin Lu, Somanshu Banerjee, Vivek Swarup, Hui Xu, Jason Chetsawang, Stephany Ramirez, Jorge S. Alfaro, Alexander Laperle, Soshana Svendsen, Clive N. Svendsen, and Shaomei Wang. Nature Communications 17 (1): 2164.

Epicardial Adipose Tissue, Coronary Plaque Progression, and Major Adverse Cardiovascular Events: A Multicenter Study. Filtz, Annalisa, Daniel Lorenzatti, Andrea Scotti, Kirtipal Bhatia, Felipe Contreras Yametti, Franco J. Cossettini, Hyuk-Jae Chang, Sang-Eun Lee, Piotr J. Slomka, Daniel S. Berman, Deepak L. Bhatt, Fay Y. Lin, Damini Dey, Leslee J. Shaw, and Leandro Slipczuk. JACC. Cardiovascular Imaging, March, S1936-878X(26)00095-1.

Novel Driver Gene MDC1 Confers Homologous Recombination Repair Deficiency and Genomic Instability in Chemoresistant Relapsing Ovarian Cancer. Diaz, Michael, Nicole Gull, Pei-Chen Peng, Kruttika Dabke, Jessica Baker, Jennifer Sun, Juan Alvarado, Benjamin Bastin, Nimisha Mazumdar, Chintda Santiskulvong, Andrew J. Li, Beth Y. Karlan, B. J. Rimel, Sarah J. Parker, Simon A. Gayther, and Michelle R. Jones. Journal of Translational Medicine, March.

Cardiology

When the Curve Bends: Low-Risk TAVR Beyond Year 5. Gupta, Aakriti, and David J. Cohen. Journal of the American College of Cardiology, February, S0735-1097(26)05436-7.

Single Cell Proteomics Reveals Novel Cell Phenotypes in Marfan Mouse Aneurysm. Saddic, Louis, Ashley Dinh, Giselle Kaneda, Amanda Momenzadeh, Lior Zilberberg, Yang Song, Mitra Mastali, Simion Kreimer, Alexandre Hutton, Ali Haghani, Jesse G. Meyer, and Sarah J. Parker. Molecular & Cellular Proteomics: MCP, March, 101549.

IgG4-Related Disease Presenting With Diffuse Coronary Atherosclerosis Characterized by Marked Lipid-Rich Necrotic Core Burden. Elisarraras, Francisco X., Robert A. Pelberg, Jacob S. Roberts, Jay A. Shah, Jeffrey Xia, Sammy Sayed, Norman E. Lepor, Jairo Aldana-Bitar, Ronald P. Karlsberg, and Geoffrey Cho. JACC. Case Reports, March, 107264.

Transcatheter Aortic Valve Intervention in Mixed Sievers Type 1 Bicuspid Aortic Valve Disease. Zito, Andrea, Michele Galasso, Won-Keun Kim, Andrea Scotti, Tommaso Fabris, Federico Arturi, Chiara de Biase, Michele Bellamoli, Nicholas Montarello, Giuliano Costa, Mesfer Alfadhel, Ofir Koren, Barbara Bellini, Mauro Massussi, Marco Angelillis, Enrico Giacomin, Riccardo Gorla, Karsten Hug, Carlo Briguori, Luca Bettari, Enrico Romagnoli, Ady Orbach, Marco De Carlo, Matthias Renker, Mario García Gómez, Carlo Trani, Alfonso Ielasi, Uri Landes, Tobias Rheude, Francesco Bedogni, Ignacio J. Amat-Santos, Antonio Mangieri, Mauro Gitto, Francesco Saia, Luca Favero, Mao Chen, Marianna Adamo, Anna Sonia Petronio, Matteo Montorfano, Raj R. Makkar, Darren Mylotte, Daniel J. Blackman, Marco Barbanti, Ole De Backer, Didier Tchètchè, Giuseppe Tarantini, Azeem Latib, Diego Maffeo, Francesco Burzotta, and Andrea Buono. Revista Espanola De Cardiologia, March, S1885-5857(26)00052-6.

Great Debate: Preventive Percutaneous Coronary Intervention Added to Optimal Medical Treatment Should Be the Default Treatment for Non-Flow-Limiting Vulnerable Plaques. Park, Duk-Woo, William E. Boden, Raffaele De Caterina, Emanuele Gallinoro, Jung-Min Ahn, C. Noel Bairey Merz, Juan Carlos Kaski, Do-Yoon Kang, Sanjay Kaul, Mario Marzilli, Carl J. Pepine, Seung-Jung Park, and Emanuele Barbato. European Heart Journal, March, ehag103.

A New Era for Imaging-Guided Optimization of PCI. Farkouh, Michael E., and Hasan Jilaihawi. JACC. Cardiovascular Interventions 19 (5): 568–70.

Stress Trajectory and Hypertension 2 to 7 Years After Delivery: A nuMoM2b-HHS Study. Nuckols, Virginia R., Bethany Barone Gibbs, Benjamin C. Brewer, Allison E. Gaffey, Jody L. Greaney, Freda Patterson, Philip Greenland, George R. Saade, William A. Grobman, Lynn M. Yee, C. Noel Bairey Merz, Judith H. Chung, Lauren H. Theilen, and Megan M. Wenner. Hypertension, March.

Dietary Intake of Macronutrients and Micronutrients in Women With Functional Hypothalamic Amenorrhea. Uddenberg, Erin R., Nancy Safwan, Regina Castaneda, Mariam Saadedine, Jenna Maughan, Maria D. Hurtado Andrade, Stephanie S. Faubion, Margareta D. Pisarska, Sarah L. Berga, JoAnn E. Manson, C. Noel Bairey Merz, and Chrisandra L. Shufelt. Journal of Women’s Health, March, 15409996261428013.

Mortality Score in Chronic Coronary Syndrome: Prediction Model From the ISCHEMIA Trial. Navarese, Eliano P., Giuseppe Talanas, Dean J. Kereiakes, Timothy D. Henry, Mariusz Gąsior, Zbigniewem Kalarus, Julia Umińska, Francesco Burzotta, Antonio Buffon, Eric Van Belle, Wojciech Wojakowski, Katarzyna Mizia-Stec, Grzegorz Smolka, Bartosz Hudzik, Daniel Cieśla, Ron Waksman, Jacek Kubica, Giuseppe M. Sangiorgi, Michael E. Farkouh, Gregg W. Stone, and Felicita Andreotti. European Journal of Preventive Cardiology, March, zwag116.

Computational Biomedicine

Cardiovascular Disease Mortality Among Women Diagnosed With de Novo Metastatic Breast Cancer. Ramin, Cody, Gillian Gresham, Jessica Li, Anja Karlstaedt, Mia Hashibe, Andriana P. Nikolova, and Katelyn M. Atkins. Cancer Epidemiology 101 (April): 103025.

Imaging

US-Guided Perineural Injections of the Upper Extremity From the Arm to the Wrist. Tivorsak, Tanya L., George R. Matcuk, Nathaniel W. Mizraki, Mitchel Seruya, and Joseph C. Giaconi. Radiographics: A Review Publication of the Radiological Society of North America, Inc 46 (4): e250118.

Medicine

Gut Microbiota and Sarcoidosis: A Concise Review. Carbone, Roberto G., Francesco Puppo, and Victor F. Tapson. Frontiers in Medicine 13: 1747012.

Non-HLA Antibody Trajectories May Predict Kidney Transplant Outcomes. Rajalingam, Raja, Tara K. Sigdel, Stalinraja Maruthamuthu, Pawan Kumar Raghav, Zoltan G. Laszik, Gilberto Da Gente, Denice Kong, Jun Shoji, and Bryan Ray. Frontiers in Immunology 17: 1729129.

Drug-Coated Balloons Beyond In-Stent Restenosis. Gupta, Rahul, Chandrashekar Bohra, Krishna Santosh Vemuri, Gaurav Arora, Amit Gulati, Isha Ranadive, Samin K. Sharma, and Amit Hooda. Reviews in Cardiovascular Medicine 27 (2): 45108.

Subcutaneous Delivery of Amivantamab in Patients With Advanced Solid Malignancies: The Phase Ib PALOMA Study. Minchom, Anna, Byoung Chul Cho, Natasha B. Leighl, Melissa L. Johnson, Joshua Sabari, Se-Hoon Lee, Ki Hyeong Lee, Yu Jung Kim, Rachel E. Sanborn, Bert O’Neil, Kamya Sankar, Anna Mitselos, Donna Zemlickis, Carmel Collins, Ali Alhadab, Pamela L. Clemens, Busola Sanusi, Eileen Berkay, Mahadi Baig, Roland E. Knoblauch, Peter Hellemans, and Matthew G. Krebs. Clinical Lung Cancer, February, S1525-7304(26)00026-4.

Response. Matusov, Yuri, Nicholas A. Kolaitis, Dael Geft, Jacqueline DesJardin, Christopher Barnett, Antoine Hage, Teresa De Marco, and Michael I. Lewis. Chest 169 (3): e120.

Small Bowel Obstruction and Frailty: A Systematic Review. Ibrahim, Aiman, Joseph Froud, Maria Lauda Tomasi, James Mitchell, Magda Sbai, and Ivan Tomasi. European Geriatric Medicine, March.

Taking Care of Your Mouth During Cancer Treatment. Maret, Delphine, Joel B. Epstein, and Emmanuelle Vigarios. JAMA Oncology, March.

The International Federation for Surgery and Other Therapies for Obesity (IFSO) Consensus on Clinical Practice in Endoscopic Sleeve Gastroplasty. Cohen, Ricardo V., Jaime Ponce, Barham Abu Dayyeh, Christine Stier, Randy Levinson, Paulina Salminen, and Gerhard Prager. Obesity Surgery, March.

The Natural Flavonoid Dihydromyricetin Targets Senescent Cells via PRDX2 and Alleviates Age-Related Diseases. Xu, Qixia, Gaoxiang Li, Hongwei Zhang, Zhirui Jiang, Xiuxia Gao, Zi Li, Larissa G. P. Langhi Prata, James L. Kirkland, Guilong Zhang, and Yu Sun. Nature Communications, March.

Editorial: Immune Checkpoint Inhibitors in Hepatocellular Carcinoma Prior to Liver Transplantation-Current Evidence and Future Directions. Rezaee-Zavareh, Mohammad Saeid, and Ju Dong Yang. Alimentary Pharmacology & Therapeutics, March.

Loss of Fungal Sensing Exacerbates Liver Injury in a Murine Model of MASLD. Pandyarajan, Vijay, So Yeon Kim, Takashi Tsuchiya, Selena Liu, Sadam H. Bhat, Jieun Kim, David M. Underhill, Mazen Noureddin, Shelly C. Lu, and Ekihiro Seki. JCI Insight, March, e190690.

Genetic Variation in Clinical Cohorts. Collen, Lauren V., Dermot P. B. McGovern, and Scott B. Snapper. The New England Journal of Medicine 394 (11): 1140–41.

Neurology

Association of Interictal Respiratory Variability and Severity of Postictal Hypoxemia After Generalized Convulsive Seizures. Caplan, Jack, Laura Vilella, Paula Lee, Roshni Nair, Deidre Dragon, Linder H. Wendt, Patrick Ten Eyck, Jennifer A. Ogren, Nuria Lecumberri, Johnson P. Hampson, M. R. Sandhya Rani, Beate Diehl, Daniel Friedman, Orrin Devinsky, Lisa M. Bateman, Ronald M. Harper, Shiqiang Tao, Guo-Qiang Zhang, Maromi Nei, Stephan U. Schuele, Samden Lhatoo, George B. Richerson, Brian Gehlbach, Rup K. Sainju, and Center for SUDEP Research (CSR). Neurology 106 (7): e214749.

Neurosurgery

Technical Performance and Interpretation of Digital Subtraction Angiography to Determine Cerebral Circulatory Arrest in Patients Being Evaluated for Brain Death/Death by Neurological Criteria: A Brief Practice Update From the Society of Vascular and Interventional Neurology (SVIN). Zaidat, Osama O., Amit Chaudhari, Roberta Novakovic-White, Michael J. Alexander, Jin Soo Lee, Qasim Bashir, Colin P. Derdeyn, Jens Fiehler, David J. Altschul, Fawaz A. Al-Mufti, Eytan Raz, Thanh N. Nguyen, Adam A. Dmytriw, Italo Linfante, Sameer A. Ansari, Mohammad AlMajali, Kaiz S. Asif, Hesham E. Masoud, Adam R. Blanden, Mohamad K. Abdalkader, Amer M. Malik, David M. Greer, Hiroshi Yamagami, Nobuyuki Sakai, Adam de Havenon, Shahram Majidi, Waldo R. Guerrero, and SVIN GAPS Committee. Stroke 6 (1): e002091.

Novel 360° Lumbar Arthroplasty: Surgical Technique and Procedural Details. Ament, Jared D., Jack Petros, Cooper Gardner, and Amir Vokshoor. North American Spine Society Journal 25 (March): 100863.

Factors Affecting Cognitive Status in Patients With Intracranial Atherosclerosis After Surgical Revascularization: A Post Hoc Analysis of the ERSIAS-PC Phase II Trial. Aguilera-Pena, Maria Paula, Miguel Tusa Lavieri, Miguel D. Quintero-Consuegra, Santiago Mendoza-Ayus, Shlee S. Song, Konrad Schlick, Jennifer Harris, Alexis N. Simpkins, Daniel Chang, Peyton L. Nisson, Jeffrey L. Saver, and Nestor R. Gonzalez. Journal of Neurosurgery, March, 1–6.

Sex-Related Differences in Outcomes of Endovascular Treatment of Distal Medium Vessel Occlusion Strokes. Salim, Hamza Adel, Vivek Yedavalli, Dhairya Lakhani, Fathi Milhem, Basel Musmar, Nimer Adeeb, Davide Simonato, Yan-Lin Li, Orabi Hajjeh, Muhammed Amir Essibayi, Nils Henninger, Sri Hari Sundararajan, Adam A. Dmytriw, et al. Clinical Neuroradiology, March.

Orthopaedics

Spondylolysis and Spondylolisthesis Is Associated With Disc Degeneration in Pediatric Patients. Chan, Vivien, Muhammad Mukarram, Kenneth D. Illingworth, and David L. Skaggs. Spine Deformity, March.

Contemporary Management of Standard Chordoma Arising in the Mobile Spine and Sacrum. Mascarenhas, Leo, Bonnie Balzer, Anthony T. Nguyen, and Joseph H. Schwab. The Journal of the American Academy of Orthopaedic Surgeons 34 (6): e832–40.

Implications of Cervical Spine Conditions on Post-Traumatic Headaches. Jimenez, Viviana, and Ilan Danan. Clinics in Sports Medicine 45 (2): 327–41.

Pediatrics

Dynamic Reprogramming of PDGFRA-Expressing Stromal Cells Facilitates WNT-Driven Transformation by Promoting a Fetal-Like State in the Intestinal Epithelium. Pellon-Cardenas, Oscar, Prateeksha Rout, Sohaib Hassan, Emily Fokas, Isha Patel, Jay Patel, Xia Qiu, Ping He, Olivia Nussbaum, Alex Wu, Rohit Kumar, Masuda Akther, Alexandra Logerfo, Siwen Wu, Daniel Wagner, Dario Boffelli, Katherine D. Walton, Kevin Tong, Jahangir Iqbal, Ruoxuan Xiao, Lei Chen, Jason R. Spence, Nicholas J. Bessman, Elisa Manieri, Ramesh A. Shivdasani, and Michael P. Verzi. Cancer Research, March.

Randomised al.Phase 2b Trial of rhIGF-1/rhIGFBP-3 (OHB-607) for Bronchopulmonary Dysplasia Prevention in Preterm Neonates: Study Protocol. Baraldi, Eugenio, Daniele De Luca, Luca Bonadies, Shinya Hirano, Satoshi Kusuda, Eduardo Bancalari, Rangasamy Ramanathan, Norman Barton, Alecia Nickless, Jane Lee, Navdeep Mahajan, and Victoria Niklas. BMJ Paediatrics Open 10 (1): e004196.

Association of Albumin Infusion With Differential Response in Pediatric Sepsis and Septic Shock: Retrospective Analysis Using a U.S. Multicenter 2012-2018 Dataset. Lee, Cheolmin Matthew, Mihir R. Atreya, Tellen D. Bennett, Reid W. D. Farris, E. Vincent S. Faustino, Jaime Fernandez Sarmiento, Alon Geva, Mark Hall, Colin Rogerson, Sareen Shah, and L. Nelson Sanchez-Pinto. Pediatric Critical Care Medicine: A Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, March.

Microbiome-Produced Nicotinic Acid Controls Colon Regional Identity and Injury Susceptibility. Rispal, Jérémie, Jasmine R. Garcia, Brisa Palikuqi, Manasa Vegesna, Dedeepya Vaka, Seung Woo Kang, Coralie Trentesaux, Juan Du, Nicola R. Realini, Paige N. Spencer, James M. Gardner, Annika Hausmann, Michael G. Kattah, Ken S. Lau, Dario Boffelli, and Ophir D. Klein. Cell, March, S0092-8674(26)00172-8.

Stress-Relaxing Granular Bioprinting Materials Enable Complex and Uniform Organoid Self-Organization. Graham, Austin J., Michelle W. L. Khoo, Vasudha Srivastava, Sara Viragova, Honesty Kim, Kavita Parekh, Kelsey M. Hennick, Malia Bird, Nadine Goldhammer, Jie Zeng Yu, Grace Hu, Natasha T. Brinkley, Lucas Pardo, Jasmine S. Amaya, Cameron D. Morley, Nishant Chadha, Paul Lebel, Sanjay Kumar, Jennifer M. Rosenbluth, Tomasz J. Nowakowski, Ovijit Chaudhuri, Ophir Klein, Rafael Gómez-Sjöberg, and Zev J. Gartner. Nature Materials, March.

Surgery

Noninvasive Biomarkers in Thymic Epithelial Tumors: A Systematic Review of cfDNA/ctDNA Detection, Molecular Profiling, and Organoid-Based Monitoring. Rocco, Raffaele, Ani Antaramian, Vikram Krishna, Philicia Moonsamy, Andrew R. Brownlee, and Harmik J. Soukiasian. Journal of Thoracic Disease 18 (2): 171.

The OligoPanc Project: An Interdisciplinary Expert Consensus Statement on Oligometastatic Pancreatic Cancer. Leonhardt, Carl-Stephan, Mustapha Adham, Shouki Bazarbashi, Irit Ben-Aharon, Regina G. H. Beets-Tan, Ugo Boggi, Thomas B. Brunner, Francesco Cellini, Arturo Chiti, Lois Daamen, Berardino De Bari, Sara De Dosso, Oliver Strobel, et al. The Lancet. Oncology 27 (3): e141–49.

Key Updates on the Version 9 AJCC/UICC Staging System for Salivary Gland Carcinoma. Huang, Shao Hui, Raja R. Seethala, Snehal G. Patel, Brian O’Sullivan, William Lydiatt, Allen S. Ho, Ali Hosni, Vincent Vander Poorten, Christine M. Glastonbury, Justin Bishop, Beth Beadle, Patrick Ha, Kiran Kakarala, Cristina P. Rodriguez, and Ian Ganly. Annals of Surgical Oncology, March.

Darvadstrocel in Patients With Crohn’s Disease With Complex Perianal Fistulas: The ADMIRE CD II Phase 3 Randomized Trial. Colombel, Jean-Frédéric, Damian Garcia Olmo, Szu-Ta Chen, Zuzana Serclova, David A. Schwartz, Steven D. Wexner, Julian Panés, Chunyuan Wu, Barbara Zhang, Michael Song, Caroline McKay, Pradeep Nazarey, Ekaterina Wright, Laura Raffals, and Phillip Fleshner. Gastroenterology, March, S0016-5085(26)00024-7.

Artificial Intelligence Shaping the Future of Adipose-Derived Therapies in Regenerative Medicine. Oubari, Haizam, David M. Smadja, Ali Mojallal, and Alexandre G. Lellouch. Discover Artificial Intelligence 6 (1): 187.

Mixed-Methods Evaluation of Surgeon Workplace Support and Obstetric Complications. Halix, Sarah J., Manuel Castillo-Angeles, Atziri Rubio-Chavez, Ekaterina L. Koelliker, Emma Askew, Deepanjana Das, Alessandra Mele, Eugene S. Kim, Michael J. Sutherland, Susan E. Pories, and Erika L. Rangel. JAMA Surgery, March.

Urology

Risk of Fracture Following Androgen Receptor Pathway Inhibitors in Men With Advanced Prostate Cancer. Lu-Yao, Grace, Nikita Nikita, Scott W. Keith, Krupa Gandhi, Amy L. Shaver, Swapnil Sharma, Christina Steinbock-Malfer, Hushan Yang, Christopher Yang, Kevin K. Zarrabi, Stephen J. Freedland, and William K. Kelly. Journal of the National Cancer Institute, March, djag061.

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