Faculty Publications June 4-11

This week’s edition of Faculty Publications includes Cedars-Sinai studies that were published June 4-11. If you have a published paper from this period that does not appear on this list, please contact Sue Marone.

Cedars-Sinai in the News

Study Suggests Millions of Breast Cancer Patients Could Safely Avoid Chemotherapy | CBS
Farin Amersi, MD

9 Well-Loved Exercises That are 'Silent Dangers' for Your Spine, According to Doctors | Huffpost
Andrew J. Bach, DO

Peptide Injections Touted as ‘Fountain of Youth.’ Spoiler Alert: They’re Not | Healthline
Bert Mandelbaum, MD

Cedars-Sinai Receives $13M Gift to Launch Health Equity Center | Becker’s Clinical Leadership
Christina Harris, MD

The Hidden Reason You Feel Exhausted and How to Feel Better Now | Mel Robbins
Brennan Spiegel, MD

Around the Practice: Setting the Stage in Advanced Cutaneous Squamous Cell Carcinoma | Cancer Network
Omid Hamid, MD

HCV+ Donor Pancreases Speed Transplant Access While Matching Outcomes | Physician's Weekly
Todd V. Brennan, MD

Tricuspid Valve Intervention: Clinical Decision-Making For Patient Selection | Cardiosource/American College Of Cardiology
Rajendra R. Makkar, MD

NIH Initiative Seeks Answers to Rising Autoimmunity | Firstword Pharma
Caroline Jefferies, PhD; Mariko Ishimori, MD

Dr. Larry Katznelson on Acromegaly, Pituitary Tumors & Better Patient Care | Talking Acromegaly & Pituitary With Tony
Laurence Katznelson, MD

Faculty Publications

Biomedical Sciences

Editorial: Immune Cell Metabolism Beyond Energy Supply - an Emerging Era to Showcase Novel Roles in Immune Effector Functions. Wu, Hao, Henry Kurniawan, Bin Zheng, and Wei He. Frontiers in Immunology 17: 1869468.

Cardiac Surgery

Outcomes Following Coronary Artery Bypass Grafting With Temporary Left Ventricular Assist Device Support. Giao, Duc M., Adham Makarem, Ameen M. Basha, Chijioke Chukwudi, Ruby Singh, Boateng Kubi, George E. Olverson, Thais Faggion Vinholo, Aabha Divya, Kamila Drezek, David A D’Alessandro, Eriberto Michel, and Asishana A. Osho. Frontiers in Cardiovascular Medicine 13: 1842278.

Transcatheter Aortic Valve Explant Experience From a High-Volume Structural Heart Center. Razavi, Allen A., Derrick Y. Tam, Aasha Krishnan, Brian Lim, Aminah Sallam, Claire Perez, Qiudong Chen, Alfredo Trento, Joanna Chikwe, and Michael E. Bowdish. Annals of Thoracic Surgery Short Reports 4 (2): 601–6.

RUNX1: A New Beat in the Heart of Diastolic Dysfunction. Elbatreek, Mahmoud H., and David J. Lefer. Cardiovascular Research, June, cvag125.

Cardiology

HIV and Syphilis Testing Among Patients Tested for Gonorrhea and Chlamydia in Emergency Departments. Sherwood, Kyla, Neil Zhang, Hollie David, Annette Dekker, Omai Garner, Elizabeth Samuels, and Paul Adamson. The Western Journal of Emergency Medicine 27 (3): 775–83.

Donor-Derived Cell-Free DNA as a Prognostic Biomarker After Heart Transplantation: The DEFINE-HT Study. Shah, Palak, Paul J. Kim, Kelly H. Schlendorf, David A. Baran, Monica M. Colvin, Adam D. DeVore, Howard J. Eisen, Kambiz Ghafourian, Michael M. Givertz, Eileen Hsich, Jaime L. W. Kennedy, Evan P. Kransdorf, Jose N. Nativi-Nicolau, Jignesh Patel, Eleni Tseliou, Omar Wever-Pinzon, Andrew Doud, Michelle S. Bloom, Sandra A. Carey, Navchetan Kaur, D. Giovanni Biagini, Kyle E. Marshall, Michael Olympios, Mandeep R. Mehra, and Josef Stehlik. JACC. Heart Failure, June, 103152.

Association of Guideline-Directed Medical Therapy for Heart Failure and Major Amputation Rates in Patients With Chronic Limb-Threatening Ischemia and Concomitant Heart Failure. Kwaah, Patrick A., Samuel A. Mensah, Clara Nkongho Tabot-Ntoung, Abraham K. Carboo, Jiun-Ruey Hu, Guangyu Tong, Eric J. Velazquez, and S. Elissa Altin. The American Journal of Cardiology, June, S0002-9149(26)00389-9.

Subtypes of Hypertension 2 to 7 Years After First Pregnancy. Brubaker, Laura H., Janet M. Catov, C. Noel Bairey Merz, Shannon Barnes, Bethany Barone Gibbs, Whitney Booker, Judith H. Chung, Philip Greenland, William A. Grobman, Sadiya S. Khan, Abbi Lane, Lisa D. Levine, Rebecca B. McNeil, Eliza C. Miller, Matthew F. Muldoon, Mitali Ray, George R. Saade, Christina M. Scifres, Robert M. Bob Silver, Hyagriv Simhan, Lynn M. Yee, and Alisse Hauspurg. Hypertension, June.

Cost Offset With Quadruple Therapy for Heart Failure. Keykhaei, Mohammad, Sina Rashedi, Stephen J. Greene, Clyde Yancy, Boback Ziaeian, Alexander T. Sandhu, Michelle Kittleson, and Gregg C. Fonarow. JAMA Cardiology, June.

Usability, Relevance, and User Engagement of a Government-Sponsored and Community Co-Designed Digital Mental Health Website During the COVID-19 Pandemic: A Pilot Study on Latino/a/x Adults. Wright, Blanche, Lily Zhang, Jocelyn I. Meza, Lupita Rodriguez, Irisela Contreras, Vanessa Terán, Alexander S. Young, Miriam Nuño, Tiffany Dzou, Sergio Aguilar-Gaxiola, and Kenneth B. Wells. JMIR Formative Research 10 (June): e72952.

Medicine

Pathogenic Germline Variants Identified in pNEN Patients During Genetic Testing. Arouchian, Tara, Alexandra Gangi, Ka Wing Fung, Teodora Dumitra, Abrahm Levi, Arsen Osipov, and Andrew E. Hendifar. Endocrine Oncology 6 (1): e250088.

Peripheral Nerve Infiltration by CAR T-Cells in a Case of Mononeuritis Multiplex After Ciltacabtagene Autoleucel. Hosoya, Hitomi, Kun-Wei Song, Kyle Dyson, Gabrielle Dufort, Bita Sahaf, Aaron Rosenberg, Surbhi Sidana, David Miklos, Hannes Vogel, Sebastian Fernandez-Pol, Srikanth Muppidi, Brian Scott, and Lekha Mikkilineni. Blood Cell Therapy 9 (2): 55–59.

Endoscopic Sleeve Gastroplasty After Solid Organ Transplantation: First Reported Case Worldwide in a Kidney Transplant Recipient. Abufarhaneh, Ehab, Ayed Alqahtani, Barham Abu Dayyeh, Ahmed Adel Amin, Ahmed Nazmi, and Dieter Broering. ACG Case Reports Journal 13 (6): e02170.

Investments in Childhood Community Resources and Subsequent Adult Health Outcomes. La Charite, Jaime, Rebecca Dudovitz, Kristen Choi, Keren Chen, Nicholas J. Jackson, Teryl Nuckols, Narayan Sastry, Adam Schickedanz, Mitchell D. Wong, and Frederick J. Zimmerman. JAMA Network Open 9 (6): e2616711.

Sex-Based Disparities in Melanoma Outcomes Across U.S. Counties: An Ecologic Study of SEER and NPCR. Adler, Robert, Esther Auerbach, Michael Kozlov, Manan Mehta, Emily Cowen, Katerina Svigos, Justin W. Marson, and Jessica Lori Feig. Journal of the American Academy of Dermatology, June, S0190-9622(26)02824-0.

The Efficacy and Safety of Etrasimod in Mildly to Moderately Active Ulcerative Colitis: Results From the Phase 2 GLADIATOR Trial. Danese, Silvio, Martina Goetsch, Laurent Peyrin-Biroulet, Andres J. Yarur, Marla Dubinsky, David T. Rubin, Brian G. Feagan, Geert D’Haens, Filip Baert, Krisztina Lazin, Guibao Gu, Jin Yu, Nervin Lawendy, Chuanbo Zang, Wenjin Wang, Sujatha Menon, Ernest H. Law, Irene Modesto, Karolina Wosik, Sarah Sidhu, Wojciech Niezychowski, and Séverine Vermeire. Clinical Gastroenterology and Hepatology: The Official Clinical Practice Journal of the American Gastroenterological Association, June, S1542-3565(26)00405-2.

Establishing Normal Myocardial Blood Flow and Myocardial Flow Reserve Values: A Rubidium-82 Positron Emission Tomography Study. Lassen, Martin Lyngby, Niels Høeg Brandt-Jacobsen, Piotr Slomka, Tine W. Hansen, Yeliz Bulut, Caroline Kistorp, Andreas Kjaer, and Philip Hasbak. European Journal of Nuclear Medicine and Molecular Imaging, June.

Letter: Pharmacotherapy for Alcohol Dependence in Cirrhosis-By Addressing One Issue Do We Create Another? Authors’ Reply. Yeo, Yee Hui, Lorenzo Leggio, and Juan Pablo Arab. Alimentary Pharmacology & Therapeutics, June.

Synergistic Senolytic-Regenerative Therapy Significantly Extends Healthspan and Lifespan. Ichim, Thomas E., Nikola Markov, Gilberto Lopes, Karenjan A. Pascual, Anastasiia Evans, Robert Reznik, Vladyslav Bykoriz, Christian A. Fortunati, Boris Minev, Roman A. Ramos, Anil Bajnath, Emma Lin, Joyce Hu, Francesco M. Marincola, Armin Rath, Barbie Barrett, Andrew Jurow, Kamlesh Kumar Sankhala, David Furman, and Boris N. Reznik. Journal of Translational Medicine 24 (1): 745.

Ultra-Processed Foods and Gastrointestinal Cancer: Epidemiologic Evidence, Mechanistic Pathways, and Clinical Implications. Tai, Derek, Kareem Latif, Pranati Shah, Gajaan Sittambalam, Rahel Demisse, Kanithra Sekaran, Jun Gong, Jane C. Figueiredo, and Louisa Liu. Cancer Epidemiology, Biomarkers & Prevention: A Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology, June.

APOL1-Risk Alleles Modulate T-Cell Receptor Signaling to Promote Allograft Rejection. Pell, John, E. M. Tanvir, Zeguo Sun, Irene Chernova, Anand Reghuvaran, Soichiro Nagata, Mateus T. Guerra, John Choi, Soltan Al Chaar, Hiroki Mizuno, Ke Dong, Xin Tian, Reika Ishibe, Barbara Franchin, Paolo Cravedi, Ashwani Kumar, Gabriel Barsotti, Hongmei Shi, Bony De Kumar, Shinobu Smithson, Wenzhi Song, John Cijiang He, Anita S. Chong, Jordan S. Pober, Stefan Somlo, Ian W. Gibson, Waldemar Popik, Zhongyang Zhang, Joseph Craft, Jamil Azzi, Naoka Murakami, Shuta Ishibe, Peter S. Heeger, and Madhav C. Menon. The Journal of Clinical Investigation, June, e193173.

P21-Senescent Cells Drive Pancreatic Islet Dysfunction Through Targetable Paracrine Signaling in Type 2 Diabetes. Iwasaki, Kanako, Priscila Carapeto, Cristian Abarca, Francesko Hela, Stephanie Sanjines, Sebastian Pena, Sandra Le, Hui Pan, Maya Jackson, Christopher Cahill, Ayush Midha, Juliana Alcoforado Diniz, Dylan Baker, Sergii Domanskyi, Sara Espinoza, Alejandro Pena, Francisco G. Cigarroa, Jillian L. Woodworth, Jeffrey H. Chuang, Vesna D. Garovic, James L. Kirkland, Tamara Tchkonia, Nicolas Musi, George A. Kuchel, Paul Robson, and Cristina Aguayo-Mazzucato. JCI Insight, June, e197310.

Using Pharmacy Technicians to Obtain Medication Histories for Emergency Department Care Among Older Adults. Qureshi, Nabeel, Joshua M. Pevnick, Sam S. Torbati, Donna Leang, Emily Mai, Yervant Malkhasian, Jackie Ho, and Carl T. Berdahl. American Journal of Health-System Pharmacy: AJHP: Official Journal of the American Society of Health-System Pharmacists, June, zxag157.

Modulation of the Bone Marrow Microenvironment by Acute B-Cell Lymphoblastic Leukemia-Derived Large Oncosomes. Samangan, Foruzandeh, Theresa Krack, Fatima Didar Kerman, Jimena Bravo, Claudius Leon Witzler, Bianca Gregorz, Wolfram Ruf, Daniela S. Krause, and Valentina R. Minciacchi. Blood Advances, June, bloodadvances.2025018905.

Statins and Survival Free of Incident Frailty Among Older US Veterans. Qazi, Saadia, Brian Charest, Nicholas M. Pajewski, Kathryn E. Callahan, Denise K. Houston, Sara E. Espinoza, Daniel E. Forman, Karen P. Alexander, Luc Djousse, J. Michael Gaziano, David R. Gagnon, Jane A. Driver, and Ariela R. Orkaby. European Heart Journal, June, ehag451.

The Family Perspectives Project: Development and Preliminary Feasibility of a Chaplain-Delivered Emotional Support Intervention for Families of Critically Ill Patients. Modes, Matthew E., Erin K. Kross, O. Kenrik Duru, Aleksandra Sherman, Sangeeta C. Ahluwalia, Anne M. Walling, Pamela Lazor, and Teryl K. Nuckols. Journal of Health Care Chaplaincy, June, 1–22.

Site- and Age-Dependent Associations Between Fusobacterium Nucleatum and Colorectal Cancer Mortality. Loroña, Nicole C., Scott LaBrie, Claire E. Thomas, Hang Yin, Jeroen R. Huyghe, Conghui Qu, Sushma Thomas, Sosun Nayemi, Hamza Ammar, Orsalem Kahsai, Li Hsu, Keith R. Curtis, Amanda Koehne, Diana G. Redwood, Li Li, Christopher I. Li, Ulrike Peters, Timothy K. Thomas, Amanda I. Phipps, Jane C. Figueiredo, and Meredith Hullar. Cancer 132 (12): e70484.

CTLA4-Ig + Anti-IL-6/IL-6R Treatment Results in Long-Term Allograft Survival and Function in Highly HLA-Sensitized Patients. Jordan, Stanley C., Sindhu Chandran, Noriko Ammerman, Edmund Huang, Jun Shoji, Xiaohai Zhang, Alice Peng, Bongha Shin, David Thomas, Reiad Najjar, Sanjeev Kumar, Peter Heeger, and Ashley Vo. Transplantation Direct 12 (7): e1952.

Upfront Medical or Surgical Treatment in Crohn’s Disease. Noor, Nurulamin M., Phillip R. Fleshner, Gil Y. Melmed, and Corey A. Siegel. The Lancet. Gastroenterology & Hepatology 11 (7): 551–52.

Condition-Specific Protocols Used in the Emergency Department Observation Unit: A Scoping Review. Samadian, Kian D., Andrew D. Luo, Malia Pollock, Henry Chen, Joshua J. Baugh, Carl T. Berdahl, Melissa A. Meeker, David A. Meguerdichian, and Christopher W. Baugh. Journal of the American College of Emergency Physicians Open 7 (4): 100425.

Neurology

From Clinical Trial to Clinical Experience: Lecanemab Therapy in a Real-World Case Series. Sonson, Michael, Golnaz Yadollahikales, Allison Flores, Ilana Lasner, Susan Lee, Zaldy Tan, Christina Quach, and Sarah Kremen. Alzheimer’s & Dementia 18 (2): e70365.

Neurosurgery

Giant Skull Base Collision Tumors in NF2-Related Schwannomatosis: Longitudinal Outcomes of Planned Selective Resection. Nisson, Peyton L., Steven Curry, Ting Zhang, Akira Ishiyama, William H. Slattery, Derald E. Brackmann, and Gregory P. Lekovic. Journal of Neuro-Oncology 178 (2): 52.

OBGYN

From Evidence to Practice: National Patterns of Hyperthermic Intra-Peritoneal Chemotherapy Use and Survival in Advanced Ovarian Cancer. Levin, Gabriel, Lucy Gilbert, Reitan Ribeiro, Rene Pareja, Raanan Meyer, and Pedro T. Ramirez. International Journal of Gynecological Cancer: Official Journal of the International Gynecological Cancer Society, May, 104762.

Vaginal Hysterectomy Versus Laparoscopic Hysterectomy for Benign Indications (Reply to Letter-to-the-Editor). Meyer, Raanan, Matthew T. Siedhoff, and Kelly N. Wright. American Journal of Obstetrics and Gynecology, June, S0002-9378(26)00286-3.

Updates in Ultrasound Imaging of Adenomyosis and Clinical Impacts. Liao, Connie, Rebecca J. Schneyer, Ogechukwu Ezike, Liron Bar-El, and Kacey M. Hamilton. Current Opinion in Obstetrics & Gynecology, June.

Orthopaedics and Sports Medicine

Complication and Union Rates of Combined Subtalar Fusion and Calcaneal Osteotomy Versus Subtalar Fusion Alone in Severe Hindfoot Deformity. Bango, Jugert, Callie Liu, Giselle Porter, Andy Tong, Edward T. Haupt, and Timothy Charlton. Foot and Ankle Surgery: Official Journal of the European Society of Foot and Ankle Surgeons, May, S1268-7731(26)00115-3.

Additional Vertebrae Are Imaged in 44% of Pediatric Patients When Limited CTs Are Ordered: A Pilot Study. Watkins, Robert G., Vivien Chan, Christopher Watterson, Elaine Butterworth, Kenneth D. Illingworth, and David L. Skaggs. Spine Deformity, June.

Pathology and Laboratory Medicine

Connecting Biospecimens and Data: A Scoping Review-Informed Conceptual Framework for Digital Infrastructure in Biobanking and Genomic Research in Low- and Middle-Income Countries. Michalska-Falkowska, Anna, and Karine Sargsyan. Frontiers in Public Health 14: 1835421.

TIMEL: Deep Learning-Statistical Integration Reveals Spatial Stromal and Immune Signatures of Aggressive Colon Cancer. Le, Minh-Khang, Xiaoying Liu, Louis Vaickus, Keluo Yao, and Joshua Levy. Journal of Pathology Informatics 22 (August): 100672. 

Pediatrics

Identifying a Refractory Shock Phenotype in Pediatric Sepsis Using a Vasoactive-Adjusted Shock Index. Lee, Cheolmin Matthew, Mihir R. Atreya, Tellen D. Bennett, Reid Wd Farris, E. Vincent S. Faustino, Alon Geva, Colin M. Rogerson, Sareen Shah, Scott Weiss, and L. Nelson Sanchez-Pinto. Shock, June.

Electroencephalographic Normalization as a Biomarker of Clinical Recovery in Down Syndrome Regression Disorder. Santoro, Jonathan D., Mackenzie Silverman, Maeve C. Lucas, Mariam M. Yousuf, Samuel T. Otey, Stella V. Gray, Brittany Jordan, Madeline D. Kahan, Latanya D. Agurs, Michelle Van Hirtum Das, Deborah Holder, Devin King, Eileen A. Quinn, Ryan Kammeyer, and Michael S. Rafii. Annals of Clinical and Translational Neurology, June.

Surgery

B7-H3 CAR T Cells Eradicate Intrahepatic Cholangiocarcinoma and Induce Durable Response. Arya, Shahrzad, Marco Ventin, Giulia Cattaneo, Martina Nebbia, Seyed Amir Sanatkar, Cristina Martin, Jingyu Jia, Bangjin Kim, Cedric A. Bailey, Nabeel M. Bardeesy, David T. Ting, Vikram Deshpande, Xinhui Wang, Sandra Ryeom, Soldano Ferrone, and Cristina R. Ferrone. Journal of Experimental & Clinical Cancer Research: CR, June.

Primary Tumor Resection in the Setting of Unresectable Metastatic Disease in Small Bowel NETs: Consensus and Controversy. Warren, Emilie A. K., Madeline D. Roorbach, Helen Ernyey, Udhayvir S. Grewal, Alexandra Gangi, Daniel M. Haperin, and Seth Concors. Endocrine-Related Cancer, June, ERC-25-0477.

The Role of Early Venous Duplex Screening in Improving Patient Safety Indicator-12 (PSI-12) Classification Accuracy: A Retrospective Cohort Study. Surti, Adam S., Robert T. Matthews, Oana Popescu, Malak Bentaleb, and Rodrigo F. Alban. Patient Safety in Surgery, June.

A Modified Delphi Consensus on Tenosynovial Giant Cell Tumour and Giant Cell Tumour of Bone: A Report From the Birmingham Orthopaedic Oncology Meeting (BOOM). Jeys, Lee M., Eduardo Botello, Richard Boyle, Walid Ebeid, Thomas Hilton, Matthew T. Houdek, Keith Hosking, Vineet J. Kurisunkal, Maritz Laubscher, Guy V. Morris, Ajay Puri, Pietro Ruggieri, Harzem Özger, et al. The Bone & Joint Journal 108-B (June): xxx.

Soluble CD146 Reflects Altered Endothelial and Metabolic Homeostasis in Peripheral Artery Disease. Oubari, Haizam, Julien Labreuche, Charlotte Reytier, Françoise Dignat-George, Jean-Paul Duong-Van-Huyen, Joseph Emmerich, Pascale Gaussem, Patrick Bruneval, Marcel Blot-Chabaud, Alexandre G. Lellouch, Nathalie Bardin, and David M. Smadja. Angiogenesis 29 (3): 41.

Rethinking CPR Training: When the ‘Man’ in Manikin Affects Performance, a Randomized Crossover Simulation Study. Nawathe, Pooja A., Falisha F. Kanji, Efren Esteves, Yujie Cui, Russell D. Metcalfe-Smith, and Tara Cohen. Resuscitation Plus 30 (July): 101364.

Urology

MUSeg-PSV: A Real-Time Deep-Learning Segmentation of the Prostate Gland and Seminal Vesicles on 29-MHz Micro-Ultrasound. Cella, Ludovica, Marco Paciotti, Giacomo Cavadini, Luca Di Stefano, Pier Paolo Avolio, Vittorio Fasulo, Andrea Piccolini, Cesare Saitta, Edoardo Beatrici, Rafal Kocielnik, Andrew J. Hung, Alberto Saita, Paolo Casale, Massimo Lazzeri, Giovanni Lughezzani, and Nicolò Maria Buffi. BJUI Compass 7 (5): e70211.

Establishing a Clinician-Prioritized Pediatric Urology Clinical Research Agenda in the United States. Corona, Lauren E., Courtney S. Streur, Jennifer J. Ahn, Vinaya Bhatia, David I. Chu, Timothy C. Boswell, Emilie K. Johnson, Kathleen M. Kan, Antoine Khoury, Paul Kokorowski, Caleb P. Nelson, Jonathan C. Routh, Konrad M. Szymanski, Briony K. Varda, Anthony J. Schaeffer, John K. Weaver, and Jonathan S. Ellison. Journal of Pediatric Urology, May, 106024.

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