Faculty Publications June 11-18
A Comprehensive Digest of Research Publications From Cedars-Sinai Investigators and a Sampling of Recent Media Coverage Featuring Faculty
This week’s edition of Faculty Publications includes Cedars-Sinai studies that were published June 11-18. If you have a published paper from this period that does not appear on this list, please contact Sue Marone.
Cedars-Sinai in the News
Cedars-Sinai Celebrates Health Sciences University Graduates | Beverly Press/Park Labrea News
Peter L. Slavin, MD; Shlomo Melmed, MB, ChB; Jeffrey A. Golden, MD
Boost Your Mood With Nature, Eat Sardines and Do a 4-Minute Workout—Plus 5 More Health Tips to Help You Have a Great Week | Yahoo! Health
Brennan Spiegel, MD
Balloon-Expandable TAVR Has Struggles Evident at 10-Year Follow-Up | Medpage Today
Aakriti Gupta, MD
The Proteomics of Precision—With Dr. Jennifer Van Eyk | The Analytical Scientist
Jennifer Van Eyk, PhD
Rare Gene Variants Linked to Spontaneous CSF Leaks | The Scientist
Wouter Schievink, MD
A Life Less Injected: New Drug Offers Hope for Acromegaly Patients | Brief Glance
Shlomo Melmed, MB, ChB
Targeted Therapies, Frontline Combos Headline Key Lung Cancer Data to Emerge From ASCO 2026 | OncLive
Karen Reckamp, MD
Highlights From Cedars-Sinai Soccer Medicine Conference | Public Now
Bert Mandelbaum, MD
Faculty Publications
Anesthesiology
In Response. Cohen, Tara N., Bruce L. Gewertz, Maurice M. Garcia, and Michael Nurok. Anesthesia and Analgesia, June.
Biomedical Sciences
Immunometabolic and Immune Regulatory Functions of Capsaicin in Cancer: Mechanistic Insights and Emerging Perspectives. Xie, Kun, Zhihong Qi, Zhuo Chen, Rui Zhang, Liang Liu, Weini Li, Duoyao Cao, Daxing Xie, and Jie Shen. Frontiers in Immunology 17: 1806015.
Linker-Dependent Variations in the Tumoricidal Activity of DZ-1-Dihydroartemisinin Conjugate Formats. Vafaeinik, Farzaneh, Sarah Helmueller, Yi Zhang, Alexandra Gangi, Heuiran Lee, Cheryn Song, Robert Figlin, Karine Sargsyan, and Yong J. Lee. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie 201 (June): 119654.
Role of Systemic and Epicardial Adipose Tissue in Cardiometabolic Disease. Khanna, Shaun, Gurkeerat Mann, Aditya Bhat, Andrew Lin, Anushka Patel, Stephen J. Nicholls, Andrew Sindone, Damini Dey, Deepak L. Bhatt, Clare Arnott, Thomas H. Marwick, and Nitesh Nerlekar. Nature Reviews. Cardiology, June.
Simvastatin Treatment in Patients With Liver Cirrhosis: A Phase II Randomized Placebo Controlled Trial Shows Reduction in IL-6 Levels. Hussain, Shehnaz K., Walid S. Ayoub, Marcia Cruz-Correa, Laura M. Kulik, Coleman Smith, Luz Maria Rodriguez, Ellen Richmond, Asad Umar, Sandra Davey, Kelly Benante, Tia Schering, Masha Kocherginsky, Ruohui Chen, Xinlei Mi, Seema A. Khan, and Marc T. Goodman. Cancer Prevention Research, June.
Cardiac Surgery
Here and Now to the Horizon: Meeting the Challenge of 10-Year Follow-Up in Transcatheter Valve Trials. Vemulapalli, Sreekanth, Roseanne White, Graeme L. Hickey, Christopher M. Mullin, Michael E. Bowdish, Robert W. Yeh, and Mitchell W. Krucoff. Journal of the American College of Cardiology 87 (23): 3330–34.
What Price Proximal Control? Left Recurrent Laryngeal Nerve Injury in Open Thoracoabdominal Aortic Aneurysm Repair. Krishna, Vikram, and Pedro Catarino. The Annals of Thoracic Surgery, June, S0003-4975(26)00561-8.
Cardiology
Ablation of Idiopathic Fascicular Ventricular Tachycardia in a Patient With Congenitally Corrected Transposition of the Great Arteries: A Case Report. Cao, Cheng, Archana Ramireddy, Dongge Li, Linhu Xia, and Hao Su. HeartRhythm Case Reports 12 (6): 671–74.
AI-CVD-HF: A Heart Failure Risk Prediction Model Based on Coronary Artery Calcium Scans Compared With PREVENT-HF. Mirjalili, Seyed Reza, Kyle Atlas, Anthony P. Reeves, Chenyu Zhang, Jakob Wasserthal, Amir Azimi, Ali Hashemi, Mohammadhossein Mozafarybazargany, Amir Ghaffari Jolfayi, Thomas Atlas, Claudia I. Henschke, David F. Yankelevitz, Javier J. Zulueta, Wenjun Fan, Jeffrey I. Mechanick, Andrea D. Branch, Zahi Fayad, Michael V. McConnell, Jamal S. Rana, Rozemarijn Vliegenthart, David J. Maron, Jagat Narula, Matthew J. Budoff, Roxana Mehran, Kim A. Williams, Predimon K. Shah, Oren Mechanic, Arthur S. Agatston, Robert A. Kloner, Nathan D. Wong, and Morteza Naghavi. American Journal of Preventive Cardiology 27 (June): 101464.
Heart Substructure Radiation Dose and Cardiac Outcomes: Contemporary Evidence and Actionable Opportunities: JACC CardioOncology State-of-the-Art Review. Atkins, Katelyn M., Gerard Walls, Andriana P. Nikolova, Joel Ferrall, Maria Oorloff, Jakub Bychowski, Kollin Kolb, Anja Karlstaedt, Joshua D. Mitchell, Raymond H. Mak, and Carmen Bergom. JACC. CardioOncology 8 (3): 211–30.
iCARDIO Alliance Global Implementation Guidelines for the Management of Obesity 2025 Focus on Prevention and Treatment of Cardiometabolic Disease. Anker, Stefan D., Linong Ji, Tammy Kindel, Andrew J. S. Coats, Dike Ojji, Adriana Puente Barragán, Peter Rossing, Shelley Zieroth, Shaaf Ahmad, Shariq Usman, Geeta Appannah, Alison L. Bailey, Jose Luis Zamorano, et al. American Journal of Preventive Cardiology 27 (June): 101445.
LL-37 IgG Levels Are Associated With Clinical Characteristics and T Follicular Cell Response in Acute Coronary Syndrome in Adults. Dimayuga, Paul C., Jianchang Zhou, Xiaoning Zhao, Kuang-Yuh Chyu, Prediman K. Shah, and Bojan Cercek. Physiological Reports 14 (12): e70914.
Patient Perspectives in Cardiovascular Research: A Qualitative Study of Barriers, Trust, and Strategies for Inclusive Clinical Trials. Niño de Rivera, Stephanie, Niurka Suero-Tejeda, Rhonda Monroe, Matthew Tang, Sarah Eslami, Aminah Sallam, Patrick O. Gee, Bjorn Redfors, Clyde Yancy, Mario Gaudino, Gregg W. Stone, John Spertus, and Ruth Masterson Creber. Circulation. Population Health and Outcomes, June, e012189.
Explainable Artificial Intelligence Models in Predicting Major Cardiovascular Events: Insights From the PolyIran and PolyPars Prospective Studies. Ghafari, Amir, Sadaf Sepanlou, Gholamreza Roshandel, Seyed Amir Ahmad Safavi-Naini, Fatemeh Malekzadeh, Maryam Sharafkhah, Amir Kasaeian, Aakriti Gupta, Shubhadarshini Pawar, Zahra Dehghanian, Amir Azimi, Mohammad Aghaei, Akram Pourshams, Hossein Poustchi, Nasrallah Jahangard, Hamid R. Rabiee, and Reza Malekzadeh. Scientific Reports, June.
Accuracy of a Deep Learning Model in Intracardiac Echocardiography. Nair, Devi, Jeffrey Winterfield, Jonathan C. Hsu, Rakesh Gopinathannair, Larry Chinitz, Naga Venkata K. Pothineni, Frederick T. Han, Bishnu P. Dhakal, Chirag Barbhaiya, Amish S. Dave, Fermin Garcia, Matthew C. Hyman, Travis Dahlen, Kristi Tanouye, Jason Yao, Shubhadarshini Pawar, Judith Buckland, Anna Gilgur, Raphael Elspas, Aakriti Gupta, Roman A. Sandler, and Joseph Z. Sokol. JACC. Advances 5 (7): 102867.
Great Debate: Surgical Aortic Valve Replacement Is First Choice for Aortic Stenosis in Patients With a Life Expectancy beyond 5 Years. Doenst, Torsten, Bernard Prendergast, Christopher J. Allen, Fabio Barili, Volkmar Falk, Hristo Kirov, Tiffany Patterson, Simon Redwood, and Helmut Baumgartner. European Heart Journal, June, ehag262.
Temporal Trends in Mitral Edge-to-Edge Repair for Primary Mitral Regurgitation. Koell, Benedikt, Sebastian Ludwig, Jessica Weimann, Dhairya Patel, Lukas Stolz, Tetsu Tanaka, Teresa Trenkwalder, Felix Rudolph, Daryoush Samim, Philipp von Stein, Cristina Giannini, Julien Dreyfus, Andrea Scotti, Jean-Michel Paradis, Marianna Adamo, Nicole Karam, Yohann Bohbot, Anne Bernard, Bruno Melica, Yusuke Kobari, Yoan Lavie-Badie, Mirjam Kessler, Omar Chehab, Simon Redwood, Edith Lubos, Ole de Backer, Marco Metra, Azeem Latib, Chiara Primerano, Christos Iliadis, Fabien Praz, Muhammed Gerçek, Erion Xhepa, Marcel Weber, Raj Makkar, Juan Granada, Thomas Modine, Erwan Donal, Jörg Hausleiter, Augustin Coisne, Daniel Kalbacher, and On Behalf Of The Prime-Mr Investigators. EuroIntervention: Journal of EuroPCR in Collaboration With the Working Group on Interventional Cardiology of the European Society of Cardiology 22 (12): e701–11.
Transcatheter vs Surgical Aortic Valve Implantation: Age vs Lifetime Perspective. Dayan, Victor, Sanjay Kaul, and Benoy Nalin Shah. European Heart Journal, June, ehag407.
10-Year Outcomes of SAPIEN 3 Transcatheter Aortic Valve Replacement or Surgery in Intermediate-Risk Patients. Nazif, Tamim M., Matheus Simonato, Raj R. Makkar, Vinod H. Thourani, Nimesh D. Desai, Vasilis Babaliaros, Kevin Greason, Joshua Rovin, Sergio Waxman, Charles Davidson, Dean J. Kereiakes, Anuj Gupta, Lowell Satler, Richard Schwartz, Samir Kapadia, S. Chiu Wong, Richard W. Smalling, Mohammad Ghani, Paul Teirstein, Isaac George, Srinivasa Potluri, Molly Szerlip, Ke Xu, David J. Cohen, Rahul P. Sharma, Philippe Pibarot, Rebecca T. Hahn, Michael J. Mack, Martin B. Leon, and PARTNER 2 Investigators. Journal of the American College of Cardiology 87 (23): 3296–3308.
10-Year Randomized Outcomes of Transcatheter or Surgical Aortic Valve Replacement in Intermediate-Risk Aortic Stenosis. Thourani, Vinod H., Philipp von Stein, Michael J. Mack, Tamim M. Nazif, Vasilis Babaliaros, Mohamad Alkhouli, Michael P. Fischbein, Nimesh D. Desai, Lowell Satler, Frank J. Zidar, Susheel K. Kodali, Irving L. Kron, Alan Zajarias, William Brinkman, Samir Kapadia, Todd M. Dewey, Mario Gössl, R. Mark Bodenhamer, Ying Ma, David J. Cohen, Rahul Sharma, Philippe Pibarot, Rebecca T. Hahn, Martin B. Leon, Raj R. Makkar, and PARTNER 2 Investigators. Journal of the American College of Cardiology 87 (23): 3309–21.
Artificial Intelligence for the Detection of Hypertrophic Cardiomyopathy From Standard Electrocardiogram. Park, Jakob, Jonathan Kermanshahchi, Christopher J. Love, Klevin Roger Reyes, Alexander Kukuev, Sarit Meshesha, Katia Kon, and Florian Rader. JACC. Advances 5 (7): 102914.
TAVR at 10 Years: Which Valve, Which Patient, Which Era? Gupta, Aakriti. Journal of the American College of Cardiology 87 (23): 3328–29.
Computational Biomedicine
Interpretation of Survival Outcomes in Multicancer Early Detection Testing Requires Caution. Houlston, Richard, Paul Pharoah, Richard Sullivan, Clare Turnbull, and Amit Sud. JCO Precision Oncology 10 (6): e2600385.
Development and Prospective Evaluation of a Real-Time Deep Learning Model for Inpatient Hypoglycemia Prediction. Momenzadeh, Amanda, Caleb Cranney, Dennis H. Chen, Elizabeth Vi Nguyen, Roma Gianchandani, and Jesse G. Meyer. NPJ Digital Medicine, June.
Risk of Pancreatic Cancer Associated With Precursor Lesions in Individuals and First-Degree Relatives: A Nationwide Cohort Study. Ludvigsson, Jonas F., Jiangwei Sun, Chen Yuan, Miroslav Vujasinovic, Johannes-Matthias Löhr, Brian M. Wolpin, and Qiao-Li Wang. Clinical Gastroenterology and Hepatology: The Official Clinical Practice Journal of the American Gastroenterological Association, June, S1542-3565(26)00443-X.
Optimizing NGN2 Dosage Enhances the Neuronal Enrichment of iPSC-Derived Neuronal Cultures. Muñoz-Estrada, Jesús, Andrew Mostafania, Lahiruni Halwatura, Ali Haghani, Yuming Jiang, and Jesse G. Meyer. Molecular & Cellular Proteomics: MCP, June, 101604.
The Missing Millions: Building Cancer Pathology Artificial Intelligence for Safety Net Populations. Jouzi, Zeynab, and Mohamed Omar. Mayo Clinic Proceedings. Digital Health 4 (3): 100374.
Imaging
Is There a Golden Hour for Thrombectomy in Intermediate-Risk Pulmonary Embolism? Insights From SYMPHONY-PE. Bangalore, Sripal, R. Dana Tomalty, Herman Kado, Sameh Sayfo, Adam Raskin, Arman Qamar, Andres Vargas Estrada, Kirema Garcia-Reyes, H. Gabriel Lipshutz, Srinivas Yallapragada, Sabah Butty, Sagar Gandhi, David Dexter, Justin Trivax, Farhan Ali, Michael Knox, Christopher Ramos, Youssef Al-Saghir, and Vivian Bishay. Circulation. Cardiovascular Interventions, June, e016573.
Medicine
Contactin-1-Associated Membranous Nephropathy After Multiple mRNA 1273 COVID-19 Vaccinations: A Case Report. Zuckerman, Jonathan E., Anthony Sisk, Elliot Parham Copen, and Stephen Copen. Glomerular Diseases 6 (1): 178–83.
The Intricate Interplay of Microbial Metabolomics and Carcinogenesis: A Spotlight on Mechanistic Pathways, Clinical Implications and Methodological Challenges. Eysha, Mostafa, Malak Fouani, Malak Munir, Mariah Black, Anna Long, Mohanad Elchouemi, Sharda Singh, and Muhammad Bilal Abid. Frontiers in Cellular and Infection Microbiology 16: 1787954.
Current Advances and Future Directions in the Management of HBV-Related Hepatocellular Carcinoma. Ibrahim, Andrew F., Julie Sang, Pojsakorn Danpanichkul, Kwanjit Duangsonk, Ju Dong Yang, Thomas A. Kerr, and Amit G. Singal. Gastroenterology Report 14 (February): goag060.
Defining Diagnostic Excellence and Missed Diagnostic Opportunity for the Emergency Department Setting. Berdahl, Carl T., Gordon D. Schiff, Arjun K. Venkatesh, Edward G. Seferian, Sam S. Torbati, Maxim P. Ptacek, Johan Carrascoza-Bolanos, Nabeel Qureshi, Teryl K. Nuckols, and Multidisciplinary ED Diagnostic Excellence Panel. Annals of Emergency Medicine, June, S0196-0644(26)00247-7.
Association Between Biologic Exposure and Relapse Incidence in Relapsing Polychondritis: A Retrospective Cohort Study. Nakayama, Yoichi, Yuki Aitani, Mirei Shirakashi, Toshiki Nakajima, Tsuneyasu Yoshida, Nozomi Nishimura, Tsuneo Sasai, Ryosuke Hiwa, Hideaki Tsuji, Shuji Akizuki, Kosaku Murakami, Ran Nakashima, Akio Morinobu, and Hajime Yoshifuji. Rheumatology, June, keag305.
Cancer Risk in Acromegaly: Reassessing the Evidence and Impact of Biochemical Control. Fleseriu, Maria, and Shlomo Melmed. The Journal of Clinical Endocrinology and Metabolism, June, dgag230.
Clinical Outcomes After Endoscopic Management of Low-Risk and High-Risk T1b Esophageal Adenocarcinoma: A Patient-Level Pooled Analysis of International Studies. Kamboj, Amrit K., Saam Dilmaghani, Rohit Goyal, D. Chamil Codipilly, Cadman L. Leggett, Allon Kahn, Andreas Probst, Helmut Messman, Zamaan Hooda, Wayne L. Hofstetter, James Tankel, Lorenzo Ferri, Fouad Otaki, Steffi van de Ven, Annemijn Maan, Arjun D. Koch, Vincent Bos, Roos E. Pouw, and Prasad G. Iyer. Clinical Gastroenterology and Hepatology: The Official Clinical Practice Journal of the American Gastroenterological Association, June, S1542-3565(26)00434-9.
Colocalization of eQTLs With Type 2 Diabetes and Glycemic Traits Using Whole-Genome Sequences in Diverse Populations From the NHLBI Trans-Omics in Precision Medicine (TOPMed) Program. Wang, Ningyuan, Daniel A. DiCorpo, Yixin Zhang, Erica Kleinbrink, Donna K. Arnett, John Barnard, John Blangero, Donald W. Bowden, April P. Carson, Yii-Der Ida Chen, Mina K. Chung, Joanne E. Curran, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium:, et al. Diabetes, June, db250557.
Mapping the Continuum of Procedural Bariatric Care: Real-World Weight Loss After Endoscopic and Surgical Interventions. Ghusn, Wissam, Nour El Ghazal, Simon J. Laplante, Eric J. Vargas, Andrew C. Storm, Barham K. Abu Dayyeh, Daniel B. Maselli, and Omar M. Ghanem. Surgical Endoscopy, June.
Placental Nicotinamide Adenine Dinucleotide Modulates the Timing of Labor. Ciampa, Erin J., Luana M. Machado, Kathy J. Lee, Amanda J. Clark, Kyle Q. Vu, Nawal A. Khan, Sarah Kispert, Samantha Armstrong, Yunping Li, Ginger L. Milne, Ashley Solmonson, S. Ananth Karumanchi, and Samir M. Parikh. Science 392 (6803): 1194–99.
Integrated Coronary CT Angiography Assessment of Plaque Vulnerability and Clinical Outcomes: The Morphology-Inflammation-Burden (MIB) Score. Andreaggi, Stefano, Riccardo Scalamera, Sekeun Kim, Kyungsang Kim, Iris McNulty, Hang Lee, Damini Dey, Jouke Dijkstra, Adrian P. Banning, Tsunekazu Kakuta, and Ik-Kyung Jang. JACC. Cardiovascular Imaging, June, S1936-878X(26)00261-5.
A Chimeric Airway Model Enables Evaluation of Essential Genes In Vivo. Calyeca, Jazmin, Lumei Liu, Kangrui Li, Katherine Drake, Hadis Najibi, Sayali Dharmadhikari, Gianni Carraro, Susan D. Reynolds, Barry R. Stripp, and Tendy Chiang. American Journal of Respiratory Cell and Molecular Biology, June, aanag128.
Pancreatitis Risk Genes Play a Major Role in Pediatric Pancreatitis: Insights From INSPPIRE. Abu-El-Haija, Maisam, Wenying Zhang, Fuchenchu Wang, Gretchen Cress, Brian Dawson, Xiaoping Su, Tyler Thompson, Nicole Kotha, Ankur Chugh, Reuven Zev Cohen, Elissa M. Downs, Douglas S. Fishman, A. Jay Freeman, Cheryl E. Gariepy, Matthew J. Giefer, Tanja Y. Gonska, Phil Greer, Amit S. Grover, Andrew Y. J. Liman, Douglas Lindblad, Quin Y. Liu, Asim Maqbool, Jacob A. Mark, Brian A. McFerron, Megha S. Mehta, Veronique D. Morinville, Kenneth Ng, Robert A. Noel, Chee Y. Ooi, Emily R. Perito, Michael Wilschanski, Yuhua Zheng, Ying Yuan, David C. Whitcomb, Aliye Uc, Mark Lowe, and Consortium for the Study of Chronic Pancreatitis, Diabetes, and Pancreatic Cancer (CPDPC). Clinical Gastroenterology and Hepatology: The Official Clinical Practice Journal of the American Gastroenterological Association, June, S1542-3565(26)00436-2.
Refined Liver MRI-Derived cT1 Thresholds Capturing Hepatic Fat Fraction Enhance Mortality Risk Prediction. Kwak, Minsun, Abdelrahman M. Attia, Mohammad Saeid Rezaee-Zavareh, Yufeng Wang, Lixia Wang, Walid S. Ayoub, Alexandar Kuo, Paul Martin, Hirsh D. Trivedi, Aarshi Vipani, Yun Wang, Stephen Pandol, Debiao Li, Shelly C. Lu, Hyun-Seok Kim, and Ju Dong Yang. JHEP Reports: Innovation in Hepatology, June, 101927.
Targeting STAT3-Mediated Lipid Metabolism Reprogramming Overcomes Chemoresistance in Acute Myeloid Leukemia. Peng, Keren, Jianshan Mo, Zhenjiao Yang, Wen Ding, Jiayu Yan, Shumin Ouyang, Minyuan Lu, Kai Zhu, Hongru Yao, Huiqin Chen, Xiongjun Xu, Peibin Yue, Jinjian Lu, Yuanxiang Wang, Shanyi Zhang, Yandong Wang, and Xiaolei Zhang. Cell Death & Disease, June.
Neurology
‘Can She Hear Me?’-Questions of Experience and Suffering in Cognitive Motor Dissociation. Hawkins, Alice. Frontiers in Neurology 17: 1858354.
Development and Validation of a Harmonized Memory Score for Multicenter Alzheimer’s Disease and Related Dementia Research. Sanderson-Cimino, Mark, Alden L. Gross, Leslie S. Gaynor, Emily W. Paolillo, Rowan Saloner, Marilyn S. Albert, Liana G. Apostolova, Brooke Boersema, Adam L. Boxer, Bradley F. Boeve, Kaitlin B. Casaletto, Hilary W. Heuer, Leah K. Forsberg, Savannah R. Hallgarth, Valentina E. Diaz, Lindsay R. Clark, Ani Eloyan, Sarah Tomaszewski Farias, Pauline Maillard, Mitzi M. Gonzales, Dustin B. Hammers, Renaud La Joie, Yann Cobigo, Amy Wolf, Benjamin M. Hampstead, Dawn Mechanic-Hamilton, Bruce L. Miller, Gil D. Rabinovici, John M. Ringman, Lina M. D’Orazio, Howie J. Rosen, Sephira G. Ryman, Jillian L. Prestopnik, David P. Salmon, Glenn E. Smith, Charles DeCarli, Kumar B. Rajan, Lee-Way Jin, Jason D. Hinman, David K. Johnson, Danielle J. Harvey, Myriam Fornage, Maria C. Carrillo, Bradford C. Dickerson, Joel H. Kramer, Adam M. Staffaroni, and ALLFTD consortium, MarkVCID study, LEADS consortium, and Diverse Vascular Contributions to Cognitive Impairment and Dementia (Diverse VCID) Study Investigators. Alzheimer’s Research & Therapy, June.
Application of the 2024 McDonald Criteria in Individuals With Nonspecific Symptoms or Incidental Imaging Findings in a Multicenter Study. Scharf, Alexandra, Jeffrey A. Cohen, Ruth Ann Marrie, Aaron E. Miller, Emmanuelle Waubant, Meghan Kilbane, Elaina Luskin, Christina J. Azevedo, Meredith Dever, Enrique Alvarez, Peter A. Calabresi, Salim Chahin, Leorah Freeman, Kunio Nakamura, Erin E. Longbrake, Ellen M. Mowry, Jiwon Oh, Paulo R. Rodrigues, Marc Ramos, Elias S. Sotirchos, Gary R. Cutter, Marwa Kaisey, Moein Amin, Karlo Toljan, Nicholas Illenberger, Michel Bilello, Jonathan Lee, Marcel Maya, Emmanuel C. Obusez, Matthew K. Schindler, Suradech Suthiphosuwan, Adam Ulano, Russell T. Shinohara, Daniel S. Reich, Andrew J. Solomon, Nancy L. Sicotte, Pascal Sati, and Daniel Ontaneda. Neurology 107 (1): e218183.
Neurosurgery
Spontaneous Spinal CSF Leaks: A Rare Variant Exome Sequencing Study and Functional Analysis. Parks, Cassie A., Mukti Singh, Elizabeth Wohler, Renan Martin, Silke Peeters, Emily E. Juzwiak, Xinyi Sun, Bart L. Loeys, Nara Sobreira, Clair Baldock, Wouter I. Schievink, and Harry C. Dietz. The Lancet. Neurology 25 (7): 664–72.
OBGYN
Robotic vs Laparoscopic Interval Cytoreductive Surgery in Stage III Ovarian Cancer: An Analysis of the National Cancer Database. Levin, Gabriel, Nuria Agusti, Isabel Beshar, Reitan Ribeiro, Roni Nitecki Wilke, Alexander Melamed, Maria D. Iniesta, Raanan Meyer, and J. Alejandro Rauh-Hain. International Journal of Gynecological Cancer: Official Journal of the International Gynecological Cancer Society 36 (7): 104768.
Isolated Ovarian Metastasis in Otherwise Cervix-Confined Adenocarcinoma of the Cervix: A Rare Clinical Conundrum. Lim, Lauren M., Sarah L. Speck, Yingao Zhang, Renata Urban, and Margaret I. Liang. Gynecologic Oncology Reports 65 (June): 102120.
Orthopaedics and Sports Medicine
Post-Operative Coronal Malalignment Is Associated With Delayed Deterioration Following Minimally Invasive Surgery for Adult Spinal Deformity. Chan, Andrew K., Nathan J. Winans, Praveen V. Mummaneni, Paul Park, Juan S. Uribe, Jay D. Turner, Vivian P. Le, Robert K. Eastlack, Richard G. Fessler, Kai-Ming Fu, Michael Y. Wang, Adam S. Kanter, David O. Okonkwo, Pierce D. Nunley, Neel Anand, Gregory M. Mundis, Peter G. Passias, Shay Bess, Christopher I. Shaffrey, Dean Chou, and International Spine Study Group. Spine, June.
Isolated Goutallier Grade 4 Supraspinatus Atrophy: A Rare Case Without Rotator Cuff Tear or Nerve Compression. Mukherjee, Trisha, Arash D. Tehranzadeh, John M. Itamura, and Brian K. Lee. Skeletal Radiology, June.
Pathology and Laboratory Medicine
Points to Consider for the Reporting of Variants of Uncertain Significance in Germline Genetic and Genomic Testing: A Statement of the American College of Medical Genetics and Genomics (ACMG). Mighton, Chloe, Aya Abu-El-Haija, Vimla Aggarwal, Yassmine M. N. Akkari, Caroline Astbury, D. Hunter Best, Laura K. Conlin, Steven M. Harrison, Nan Jiang, Paul Kruszka, Dianalee McKnight, Tiffany T. Nguyen Dolphyn, Farid Barquet Ramos, Christie P. Thomas, Lora J. H. Bean, Heidi L. Rehm, and Laboratory Quality Assurance Committee. Genetics in Medicine: Official Journal of the American College of Medical Genetics, June, 102583.
Pediatrics
Antibody Repertoire Associated With Clinically Diverse Presentations of Pediatric SARS-CoV-2 Infection. Bruiners, Natalie, Rahul Ukey, Katherine C. Konvinse, Marlayna Harris, Muge Kalaycioglu, Jason H. Yang, Emily Yang, Usha Ganapathi, William Honnen, Tracy Andrews, Benjamin Richlin, Christian Suarez, Sunanda Gaur, Sabah Kalyoussef, Elizabeth Ricciardi, Uzma N. Hasan, William Cuddy, Aalok R. Singh, Dawn Wahezi, Evin Rothschild, Patrick W. Brady, Saquib A. Lakhani, Hulya Bukulmez, David C. Kaelber, Yukiko Kimura, Abraham Pinter, Stacey Napoli, Sandra Moroso-Fela, Lawrence C. Kleinman, Daniel B. Horton, Paul J. Utz, and Maria Laura Gennaro. Scientific Reports, June.
Paediatric Therapeutic Development Workshop on Rhabdomyosarcoma. Baxter, Joseph S., Claudia Montiel Equihua, Jan J. Molenaar, Jamie Aye, Gianni Bisogno, Patricia Blanc, Willemijn Breunis, Julia Chisholm, Jacquelyn Crane, Sam Daems, Laura Danielson, Bram de Wilde, Cancer Grand Challenge PROTECT team, et al. British Journal of Cancer, June.
Radiation Oncology
LPAR4 Mediates Resistance to Interferon-Induced Stress in Soft Tissue Sarcoma. Xiao, Jin-Fen, Emily Y. Ko, Ashley Smith, Roberta Piras, Annaliese Fowler, Kristin Ishaya, Longqiang Wang, Bin Wang, Adriana Paulucci-Holthauzen, Sharon M. Landers, Angela D. Bhalla, Keila E. Torres, Diana Shamsutdinova, Khalida M. Wani, Alexander J. Lazar, Emily Z. Keung, Neeta Somaiah, Elise F. Nassif Haddad, and Jlenia Guarnerio. Science Advances 12 (24): eaef1962.
Do Uniform Fasting Instructions Lead to Reproducible Stomach Volumes in Patients Being Treated With Radiation to the Pancreas? Nguyen, Enya, Doris N. Rusu, Jennifer L. Dolan, and Parag J. Parikh. Practical Radiation Oncology, June, S1879-8500(26)00192-X.
Surgery
Three-Year Outcomes of Endovascular Repair of Descending Thoracic Aortic Lesions With a Single-Branched Endograft for Left Subclavian Artery Preservation. Hughes, G. Chad, Michael D. Dake, Himanshu J. Patel, Jon S. Matsumura, Ali Azizzadeh, Nimesh Desai, William T. Brinkman, Dennis Gable, Sukgu Han, and Gustavo Oderich. JTCVS Structural and Endovascular 9 (March): 100096.
NOX4 Suppresses Malignant Progression in Prostate Adenocarcinoma and Functions as a Potential Diagnostic Biomarker. Hu, Jimeng, Min Zhou, Xiaobo Wu, and Mengbo Hu. Translational Andrology and Urology 15 (5): 175.
Operationalizing Patient and Stakeholder Engagement in High-Acuity Trials: Lessons From IMPROVE-AD. Sipelii, Motutama, Jake Howitt, Keeley McConnell, Sreekanth Vemulapalli, Gregory A. Magee, Laura Drudi, Nolan C. Cirillo-Penn, Elizabeth L. Chou, Firas F. Mussa, Cali Johnson, and Sherene Shalhub. Seminars in Vascular Surgery 39 (2): 173–79.
Safety and Effectiveness of the Colovac Anastomosis Protection Device Compared With Diverting Ileostomy After Low Anterior Resection: Protocol for an International, Multicentre, Prospective, Non-Randomised Comparative Study (SAFE-3). Pastier, Clément, Patricia Sylla, Sang W. Lee, Antonino Spinelli, Niels Komen, John Marks, Joseph Martz, Rebecca Rhee, Justin Maykel, Jorge Marcet, Quentin Denost, Karen Zaghiyan, Jennifer S. Davids, Nivedh Paluvoi, David Hiller, Elisabeth C. McLemore, Leon Maggiori, Andre D’hoore, Mehraneh D. Jafari, Vitaliy Poylin, Christopher Jerome Buzas, Jean-Jaques Tuech, and Jérémie H. Lefèvre. BMJ Open Gastroenterology 13 (1): e002235.
Through the Scope, Through the Years: Declining Trends in Laparoscopic Common Bile Duct Exploration. Bloom, Matthew B., Nicholas Gonsalves, Yufei Chen, Joshua Tseng, Sayeh Mirshojae, Rushil Rawal, Farin Amersi, and Edward Phillips. Surgical Endoscopy, June.
Longitudinal Validation of ENLIGHT, an AI Predictor of Immunotherapy Response and Resistance, in Pan-Cancer Cohorts. Park, Changsu L., Gal Dinstag, Carlos D. Holanda Lopes, Scott Strum, Jeffrey P. Bruce, Omer Tirosh, Saugato Rahman Dhruba, Danh-Tai Hoang, Tuvik Beker, Eldad Shulman, Anna Spreafico, Philippe L. Bedard, Sofia Genta, Albiruni R. Abdul Razak, Eytan Ruppin, Ranit Aharonov, and Lillian L. Siu. NPJ Precision Oncology, June.
Porcine Xenotransplantation in the Clinical Era: Converging Advances and Unresolved Barriers on the Path to Clinical Translation - a Narrative Review. Henderson, Douglas, Leonard Knoedler, Olivier Mathieu, Nathalie Rouas-Freiss, Curtis L. Cetrulo, Gilles Lemaitre, David M. M. Smadja, Nicolas O. Fortunel, and Alexandre G. G. Lellouch. Frontiers in Immunology 17 (June).
Negative Angiography Does Not Exclude Ulnar Artery Aneurysm in Hypothenar Hammer Syndrome. McCreery, Chloe, Justin H. Wong, Tanner Kim, David Kulber, and Peter Deptula. Journal of Hand Surgery Global Online 8 (4): 101066.
Patient-Reported Outcomes Following Chest Masculinization Surgery in Transmasculine Individuals: A Prospective Study. Sprunger, Yannick, Kevin Serror, Raffaele Aguglia, Guillaume Mulier, Olivier Mathieu, Jad Bissar, Marc Chaouat, and David Boccara. JPRAS Open 50 (July): 493–502.
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