Faculty Publications Feb. 19-26

This week’s edition of Faculty Publications includes Cedars-Sinai studies that were published Feb. 19-26. If you have a published paper from this period that does not appear on this list, please contact Sue Marone.

Cedars-Sinai in the News

6 in 10 Women Will Develop Heart Disease or Stroke by 2050, Heart Association Projects | STAT | Scientific American
C. Noel Bairey Merz, MD 

What Happens to Black Women’s Minds When a Birth Advocate Dies Newly Postpartum? | Ebony
Olusinmi Bamgbose, MD

AI-Selected Biomarker Guides First-Line Treatment Selection in Advanced Pancreatic Cancer | The ASCO Post
Andrew E. Hendifar, MD

Disease Patterns Vary With Genetic Ancestry for Hispanic Patients With IBD | HealthDay
Talin Haritunians, PhD

The Hydration Trap: Why Your Healthy Water Habit Might Be Backfiring | MSN
Natasha Trentacosta, MD

How Health Systems are Tackling Behavioral Health Fragmentation | Becker’s Behavioral Health
Itai Danovitch, MD

Higher Reintervention Risk With TAVI Emerges at 6 to 7 Years in Evolut Low Risk Trial | TCTMD
Aakriti Gupta, MD

Urinary Tract Infection (UTI) Treatment: Medication and Lifestyle Changes | Everyday Health
Andrew Chen, MD

Could This Common Bacteria in the Eye be Driving Alzheimer's Disease? | Medical News Today
Maya Koronyo-Hamaoui, PhD

A Swallowable Balloon for Weight Loss Gets FDA Approval | Everyday Health
Rabindra Watson, MD

Faculty Publications

Biomedical Sciences

Molecular Calcification Imaging and Ascending Aortic Disease in Patients With a Bicuspid Aortic Valve. Nash, Jennifer, Samuel Debono, Krithika Loganath, Beth Whittington, Evangelos Tzolos, Maaz Syed, Laura Clark, Tijana Mitic, Adriana A. S. Tavares, Mark Macaskill, Stephanie L. Sellers, Tim Clark, Scott Semple, Gillian MacNaught, Edwin J. R. van Beek, Damini Dey, Piotr Slomka, Niki Walker, Jillian Madine, Mark Field, Riaz Akhtar, Rachael O. Forsythe, Michelle C. Williams, Marc R. Dweck, David E. Newby, and Alexander J. Fletcher. JAMA Network Open 9 (2): e2560385.

Cardiac Surgery

The 2025 Accra Declaration on Upskilling and Cost- Effective Cardiac Surgery in Africa. Yankah, A. Charles, Jonathan Nwiloh, Carlos A. Mestres, Abdelmalek Bouzid, Tom Philip Mwambu, Andrew J. Duncan, Mohamed Debieche, Samuel I. Omokhodion, Uvie U. Onakpoya, Matthias Angres, Siyasebow M. Nademo, Gilbert Oburu, Nana-Akyaa Yao, Kow Entsua-Mensah, Darshan Reddy, Manuel Antunes, Walter J. Gomes, Joseph A. Akamah, Mustafa Yigitbasi, Daniel Gerhard Buys, Regina Bokenkamp, Willie Koen, Francis E. Smit, and Joanna Chikwe. European Journal of Cardio-Thoracic Surgery, 68 (2): ezag036.

The 2025 Accra Declaration on Upskilling and Cost-Effective Cardiac Surgery in Africa. Yankah, A. Charles, Jonathan Nwiloh, Carlos A. Mestres, Abdelmalek Bouzid, Tom Philip Mwambu, Andrew J. Duncan, Mohamed Debieche, Samuel I. Omokhodion, Uvie U. Onakpoya, Matthias Angres, Siyasebow M. Nademo, Gilbert Oburu, Nana-Akyaa Yao, Kow Entsua-Mensah, Darshan Reddy, Manuel Antunes, Walter J. Gomes, Joseph A. Akamah, Mustafa Yigitbasi, Daniel Gerhard Buys, Regina Bokenkamp, Willie Koen, Francis E. Smit, and Joanna Chikwe. The Annals of Thoracic Surgery, February, S0003-4975(26)00014-7.

Cardiology

Impact of Pre-Procedural Requirements on Time to Aortic Valve Replacement: Transcatheter AVR vs Surgical AVR. Stinis, Curtiss, Sean Tunis, Sandra Lauck, Aakriti Gupta, Shannon Murphy, Soumya Chikermane, Seth Clancy, and Mark Russo. American Heart Journal Plus: Cardiology Research and Practice 61 (January): 100698.

Targeting Immunometabolic Pathways With AZD1656 Alleviates Inflammation and Metabolic Dysfunction in Type 2 Diabetic Cardiomyopathy. Anderson, Stephanie, Anja Karlstaedt, Megan Young, Loucia Karatzia, Fenn Cullen, Jianmin Chen, Caroline E. O’Riordan, Michael R. Barnes, Zorana Štaka, Lauren J. Albee, Conor Garrod-Ketchley, Sanushi Dambure, Hiran A. Prag, Filip Cvetko, Jack J. J. J. Miller, Christoph Thiemermann, Andrew J. M. Lewis, Michael P. Murphy, David M. Smith, Sian M. Henson, Damian J. Tyler, and Dunja Aksentijevic. Nature Cardiovascular Research 5 (2): 138–54.

Use of a Novel, Self-Expanding Coronary Sinus Reducer to Treat Symptomatic Epicardial and Microvascular Ischemic Heart Disease: Preclinical and First-in-Human Experience. Giannini, Francesco, Julio I. Farjat-Pasos, Salvatore Brugaletta, Jose Antonio Baz, Neil Fam, Mariusz Tomaniak, Milosz Jaguszewski, Juan Del Portillo, Manel Sabaté, Tim van de Hoef, Josep Rodés-Cabau, Samit Shah, Victor Alfonso Jimenez Diaz, Bruce A. Samuels, and Jean-Michel Paradis. Journal of the Society for Cardiovascular Angiography & Interventions 5 (2): 104070.

Using Subcutaneous Nerve Stimulation to Control Atrial Fibrillation. Chen, Peng-Sheng, Xiao Liu, Tiffany G. Perry, Robert J. Siegel, Alexander Tuchman, Anxhela Kote, Jewel N. Reaso, Kathleen A. Lane, Carine Rosenberg, K. Taiga Andersson, Susan Straka, Lan S. Chen, Thomas H. Everett, Michael M. Shehata, Ashkan Ehdaie, Xunzhang Wang, Eugenio Cingolani, Archana Ramireddy, Eric D. Braunstein, and Xiaochun Li. Heart Rhythm O2 7 (2): 255–63.

Adaptive Blood Pressure-Modulated Atrial Pacing in Hypertensive HFpEF Patients: A Randomized, First-in-Human Study. Burnam, Michael H., Santosh Kumar Sinha, Mukesh Jitendra Jha, Sanjay Kumar Sharma, Amitesh Nagarwal, Rohit Chopra, and Eli S. Gang. ESC Heart Failure 13 (1): xvaf020.

Invasive and Medical Management Approaches to Non-Acute Myocardial Ischaemic Syndromes. Chiu, Nicholas, Deepak L. Bhatt, Raffaele De Caterina, Torsten Doenst, Hristo Kirov, Victor Dayan, David P. Faxon, Sanjay Kaul, Divaka Perera, John D. Puskas, Philippe Gabriel Steg, and William E. Boden. Nature Reviews. Cardiology, February.

Computational Biomedicine

Compartment-Specific Tumor-Infiltrating Immune Cells and Prognosis in Breast Cancer. Bernstein, Aaron J., Renske Keeman, Amber N. Hurson, Fiona M. Blows, Manjeet K. Bolla, Jodi L. Miller, Roger L. Milne, Hugo Horlings, Alexandra J. van den Broek, Clara Bodelon, James M. Hodge, Alpa V. Patel, Marjanka K. Schmidt, et al. iScience 29 (2): 114759.

Agentic AI and the Rise of in Silico Team Science in Biomedical Research. Li, Binglan, Anil Kumar Saini, Jose Guadalupe Hernandez, and Jason H. Moore. Nature Biotechnology, February.

High Normal Parathyroid Hormone and Cardiovascular and Total Mortality: Sex and Age Disparities in the ELSA-Brasil Study. Okubo, Jessica, Eduardo Z. Kawahara, Gustavo H. Mori, Vinicius F. Calsavara, Ana Claudia Latronico, Paulo A. Lotufo, Isabela M. Bensenor, and Madson Q. Almeida. The Journal of Clinical Endocrinology and Metabolism, February, dgag076.

Emergency Medicine

Social Risks of Geriatric Patients Presenting to the Emergency Department. Stillman, Kaytlena, Lea Dahlke, Levon Aharonyan, Marie Lauzon, Alexander Lawton, Claude Stang, Joel Geiderman, Sonja Rosen, and Sam Torbati. BMC Geriatrics, February.

Medicine

Prevention Strategies for All Hospital-Onset Urinary Tract Infections: Best Practice Consensus Recommendations. Septimus, Edward J., Lily A. Arya, Rebecca Crapanzano-Sigafoos, Roger Dmochowski, Opal Dy, JoAnn Emer-Seltun, Sandra Engberg, Robert Garcia, Mikel Gray, Michael Kennelly, Sarah Krein, Jennifer Meddings, Rekha Murthy, Diane K. Newman, AnnMarie Pettis, Sara Reese, Emily Sidlow, and Kathleen Vollman. Open Forum Infectious Diseases 13 (2): ofag060.

A Systematic Review of Efficacy in Irritable Bowel Syndrome: How the Number Needed to Treat May Be a Misleading Metric. Busam, Jonathan A., Nisha Batta, Ali Rezaie, and Mark Pimentel. The American Journal of Gastroenterology, February.

A Small Molecule Inhibitor of ARF GTPase Protein 1 Limits Liver and Colon Cancer Cell Growth and Metastasis. Peng, Hui, Jyoti Chhimwal, Wei Fan, Jiaohong Wang, Lucía Barbier-Torres, Sonal Sinha, Avradip Chatterjee, Yi Zhang, Maria Lauda Tomasi, José M. Mato, Ramachandran Murali, and Shelly C. Lu. Cell Death & Disease, February.

Begin at the Beginning: Serum TNFa in Brain Dead Donors as a Biomarker for Kidney Transplant Outcomes. Qian, Long Anna, Peter Heeger, and Madhav C. Menon. American Journal of Transplantation, February, S1600-6135(26)00106-1.

Regulation of Murine Follicle-Stimulating Hormone β Subunit Transcription by Newly Identified Enhancers. Jin, Yangfan, Hailey Schultz, Luisina Ongaro, Gauthier Schang, Xiang Zhou, Carlos Agustin Isidro Alonso, Michel Zamojski, German Nudelman, Natalia Mendelev, Shinsuke Onuma, Corrine K. Welt, Louise M. Bilezikjian, Stuart C. Sealfon, Frederique Ruf-Zamojski, and Daniel J. Bernard. Endocrinology, February, bqag020.

Dentists’ Knowledge and Practices in Supportive Care: A French National Survey. Bataille, Caroline de, Colas Prunier, Manon Saucourt, Joel B. Epstein, Emmanuelle Vigarios, and Delphine Maret. Supportive Care in Cancer, 34 (3): 235.

Fisetin-Mediated Topical Modulation of Senescent Cells in Skin Improves Wound Healing Dynamics in Diabetic Mice. Numani, Asfia, Margarita Carrasco-Jeldres, Barbara Hernandez-Rovira, K.-Raman Purushothaman, Matthew M. Melin, James L. Kirkland, and Saranya Wyles. Advances in Wound Care, February, 21621918261426580.

Phase II Study of Pegvorhyaluronidase Alfa (PEGPH20) and Pembrolizumab for Patients With Hyaluronan-High, Pretreated Metastatic Pancreatic Ductal Adenocarcinoma: PCRT16-001. Chiorean, Elena Gabriela, Sheela R. Damle, David B. Zhen, Martin Whittle, Ben George, Howard Hochster, Andrew L. Coveler, Andrew Hendifar, Tomislav Dragovich, Rachael A. Safyan, Gentry T. King, William P. Harris, Barbara Dion, Amy Stoll D’Astice, Arthur Lee, Shelley Thorsen, Sita Kugel, Adam Rosenthal, and Sunil Hingorani. Cancers 18 (3).

Cellular Heterogeneity of HTII-280-Labeled Epithelial Cells in Healthy and Fibrotic Human Lungs. Gomez, Angela C., Kazuya Koyoma, Alicia Gamboa, Xiangrong Guan, Xue Liu, Tanyalak Parimon, Dianhua Jiang, Jiurong Liang, Paul W. Noble, Peter Chen, Barry R. Stripp, and Changfu Yao. American Journal of Respiratory and Critical Care Medicine, January, aamaf106.

Palmitoleic Acid Loss Links Pulmonary Dysbiosis to Lung Injury After Single-Lung Ventilation. Najibi, Hadis, Keyi Li, and Changfu Yao. American Journal of Respiratory Cell and Molecular Biology, January, aanag005.

iCLAP: An Innovative Method for Integrable Co-Detection of Low-Abundance Antigens With High-Plex Immunostaining. Wu, Fan, Shuyuan Zheng, Yani Chen, Peijia Ye, Moo Joong Kim, Seojin Lee, Geroge Kuo, Shriya Pillan, Ruihan Yuan, Kyu Sang Han, Bofei Yu, Qingfeng Zhu, Sarah M. Shin, Courtney D. Cannon, Gabriele Pierre, Kanako Iwasaki, Cristina Aguayo-Mazzucato, Nicolas Musi, George A. Kuchel, Birgit Schilling, Laura D. Wood, Won Jin Ho, Robert A. Anders, Denis Wirtz, and Pei-Hsun Wu. Nature Communications, February.

Variability in First Academic Medicine Job Offers in Pulmonary and Critical Care Medicine. Olson, Emily M., Matthew E. Modes, Timothy J. Rowe, Patrick G. Lyons, Nicholas E. Ingraham, Nandita R. Nadig, Clara J. Schroedl, and Catherine A. Gao. ATS Scholar, February, aapag010.

What’s in a Number: Do Transfer Rates Reflect Nursing Home Quality? Saliba, Debra, Vincent Mor, Kisa A. Hilliard, Amy L. Mochel, Margaret Baumann, Rebecca Boxer, Heather D’Adamo, Hiroshi Gotanda, Kim W. House, Seema Joshi, Linda Sohn, Arti Tayade, Sarah Tubbesing, Dan R. Berlowitz, Orna Intrator, Roee Gutman, Ciaran S. Phibbs, and Joseph G. Ouslander. Journal of the American Geriatrics Society, February.

Neurosurgery

Does Change of Spinal Diverticular Size Predict the Site of de Novo Recurrent CSF-Venous Fistulas in Patients With Spontaneous Intracranial Hypotension? Schievink, Wouter I., Marcel M. Maya, Rachelle B. Taché, Ravi S. Prasad, Vikram Wadhwa, and Franklin G. Moser. AJNR. American Journal of Neuroradiology, February, ajnr.A9258.

OBGYN

Minimally Invasive Surgery Versus Open Surgery for Uterine Sarcomas - a Retrospective Study. Levin, Gabriel, Melica Nourmoussavi Brodeur, Raanan Meyer, Yael Tal Bliman, Shannon Salvador, Susie Lau, and Walter Gotlieb. Journal of Gynecology Obstetrics and Human Reproduction, February, 103147.

Assessing Training Practices and Gaps for Staff Involved in the Delivery of Oncology Financial Navigation: A Qualitative Study. Cordero, Gaby, Maria Pisu, Shu-Fan Chen, Elizabeth Ward, and Margaret I. Liang. Current Oncology 33 (2): 130.

Orthopaedics

Contemporary Tumor Histology Grouping for Survival Prediction of Patients With Metastatic Long-Bone Disease Undergoing Surgery. Groot, Tom M. de, Olivier Q. Groot, Rene H. Kuijten, Michelle R. Shimizu, Kevin A. Raskin, Erik T. Newman, Job N. Doornberg, Paul C. Jutte, Santiago A. Lozano-Calderón, and Joseph H. Schwab. The Journal of the American Academy of Orthopaedic Surgeons, November.

Post-Operative Survival and Use of Systemic Therapy in Metastatic Long-Bone Disease: 12 Years of Institutional Experience. Groot, Tom M. de, Joris R. H. Hendriks, Michelle R. Shimizu, Jens P. Te Velde, Olivier Q. Groot, Erik T. Newman, Kevin Raskin, Job N. Doornberg, Paul C. Jutte, Santiago Lozano-Calderón, and Joseph H. Schwab. Journal of Bone Oncology 57 (April): 100751.

Parental Perspectives on Youth Sport Specialization: Insights on Motivators Across Specialization Levels. Riesenberg, Josh, David M. Bazett-Jones, Julie Dyke, Lauren Butler, Gregory A. Walker, Tamara C. Valovich McLeod, Tracy Zaslow, Traci Snedden, Eric Post, and Sophia Ulman. Frontiers in Sports and Active Living 8: 1736749.

Physical Medicine & Rehabilitation

Myofascial Pelvic Floor Dysfunction as a Hidden Contributor to Urinary Symptoms. Ackerman, Anne Lenore, and Andrea Wise-Fuchs. Minerva Obstetrics and Gynecology, February.

Radiation Oncology

Survey of Work-From-Home Experiences Among Medical Physicists in Southern California During and After the COVID-19 Pandemic. Liu, Xiaoyu, Jennifer Zhang, David Hoffman, Varun Sehgal, Zhilei L. Shen, Chengyu Shi, X. Sharon Qi, Jing Cui, Amy S. Yu, Margaret Barker, Dan Ruan, and Steve Goetsch. Journal of Applied Clinical Medical Physics 27 (3): e70523.

Surgery

Image Cytometry Differentiates CD34+ and CD133+ Profiles of Very Small Embryonic-like Stem Cells. Smadja, David M., Anna Chipont, Léa Guyonnet, Alexandre G. Lellouch, Audrey Cras, Marion Alcantara, and Coralie L. Guerin. Cell Transplantation 35: 9636897261422302.

The Impact of Chemotherapy on Floating vs. Attached Colorectal Cancer Cells: An In-Vitro Study. Khosrawipour, Veria, Agata Mikołajczyk-Martinez, Carolina Khosrawipour, Patrycja Salata, Zdzisław Kiełbowicz, Ewa Nicpon, Przemyslaw Przadka, Zhiwen Zhang, Wojciech Kielan, Shiri Li, Jacek Bania, Kamila Kuzniak, Kacper Zieliński, Mouhamed El-Aita, and Wolfram T. Knoefel. Frontiers in Oncology 16: 1697776.

Factors Influencing Refusal of Adjuvant Chemotherapy in Non-Small Cell Lung Carcinoma. Perez, Claire, Vikram Krishna, Drew Bolster, Kellie Knabe, Raffaele Rocco, Philicia Moonsamy, Harmik J. Soukiasian, and Andrew R. Brownlee. Clinical Lung Cancer 27 (2): 108–16.

Microsurgery on Steroids: The Impact of Chronic Immunosuppressive Therapy on Outcomes Following Free Flap Breast Reconstruction. Knoedler, Samuel A., Thomas Schaschinger, Tobias Niederegger, Leonard Knoedler, Omar Allam, Felix Klimitz, Joanna Kempa-Timler, Karen Lynn Zhao, Stefano Pompei, Barbara Kern, Henriette Grundig, Giuseppe Sofo, Francesco Mazzarone, Fortunay Diatta, and Martin Kauke-Navarro. Clinical Breast Cancer, January, S1526-8209(26)00015-7.

Macrophages From Latently Infected Mice Have Trained Immunity to HSV-1. Jaggi, Ujjaldeep, Shaohui Wang, Satoshi Hirose, Deepak Arya, and Homayon Ghiasi. Investigative Ophthalmology & Visual Science 67 (2): 49.

Creating Engineered NAC Flaps Using in Vivo Revascularization: A Proof-Of-Concept Study. Berkane, Yanis, Alperen Abaci, Bradley W. Ellis, Loïc van Dieren, Edvin Hendi, Haizam Oubari, Nicolas Bertheuil, Ruben Oganesyan, Curtis L. Cetrulo, Michelle E. McCarthy, Mark A. Randolph, Alexandre G. Lellouch, and Basak E. Uygun. Stem Cell Reviews and Reports, February.

Psychosocial Safety Is Patient Safety: Gender-Affirming Care as an Exemplar for Health Equity. Barton, Hanna J., Tara N. Cohen, Falisha F. Kanji, Victor Trasvina, Jennifer T. Anger, and Alan J. Card. Journal of Patient Safety, February.

Soluble ST2 Fails to Reflect Persistent Endothelial Dysfunction or Symptoms in Post-Acute Sequelae of COVID-19. Smadja, David M., Sven Günther, Jeanne Rancic, Alexandre Lellouch, Bertrand Renaud, Jean-Luc Diehl, and Aurélien Philippe. Annales Pharmaceutiques Francaises, February, S0003-4509(26)00033-7.

BRCA1-Associated Protein 1 (BAP1) in Human Cancer and Its Emerging Role as a Novel Potential Therapeutic Target. Liguori, Luigi, Giovanna Polcaro, Valentina Pagliara, Rosario De Feo, Giulia Cattaneo, Marco Ventin, Chiara Camillo, Enrica Quattrocchi, Maoyang Qi, Liti Zhang, Erica Daniels, Eduardo Tejeda-Polanco, Stefano Pepe, Cristina R. Ferrone, and Francesco Sabbatino. Current Oncology Reports 28 (1): 18.

The Current State of Acute Care Surgery Workforce and Practice Models: A Joint Statement by the American Association for the Surgery of Trauma, the American College of Surgeons Committee on Trauma, the Eastern Association for the Surgery of Trauma, and the Western Trauma Association. Staudenmayer, Kristan L., Galinos Barmparas, Stephen L. Barnes, Walter L. Biffl, Mitchell J. Cohen, Kimberly A. Davis, Marc de Moya, Amy J. Goldberg, Bellal Joseph, R. Shayn Martin, Patrick B. Murphy, Anne G. Rizzo, Michael Rotondo, Stephanie A. Savage, Jason W. Smith, S. Rob Todd, Ben L. Zarzaur, and Eileen Bulger. Journal of the American College of Surgeons, February.

The Current State of Acute Care Surgery Workforce and Practice Models: A Joint Statement by the American Association for the Surgery of Trauma, the American College of Surgeons Committee on Trauma, the Eastern Association for the Surgery of Trauma, and the Western Trauma Association. Staudenmayer, Kristan L., Galinos Barmparas, Stephen L. Barnes, Walter L. Biffl, Mitchell J. Cohen, Kimberly A. Davis, Marc de Moya, Amy J. Goldberg, Bellal Joseph, R. Shayn Martin, Patrick B. Murphy, Anne G. Rizzo, Michael Rotondo, Stephanie A. Savage, Jason W. Smith, S. Rob Todd, Ben L. Zarzaur, and Eileen Bulger. The Journal of Trauma and Acute Care Surgery 100 (3): 380–85.

ASO Visual Abstract: Prognostic Value of Non-Nodal Regional Metastases in Predicting Sentinel Lymph Node Status in Cutaneous Melanoma: Multicenter Analysis of the Sentinel Lymph Node Working Group Database. Riaz, Nazia, Stanley P. Leong, Mohammed Kashani-Sabet, Richard L. White, John T. Vetto, Schlomo Schneebaum, Cristina O’Donoghue, J. Harrison Howard, Eli Avisar, Jukes P. Namm, Heidi Kosiorek, Barbara Pockaj, Mark Faries, Giorgos Karakousis, Jonathan S. Zager, and Roger Olofsson Bagge. Annals of Surgical Oncology, February.

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