Faculty Publications Aug. 6-13
A Comprehensive Digest of Research Publications From Cedars-Sinai Investigators and a Sampling of Recent Media Coverage Featuring Faculty
This week’s edition of Faculty Publications includes Cedars-Sinai studies that were published Aug. 6-13. If you have a published paper from this period that does not appear on this list, please contact Sue Marone.
Cedars-Sinai in the News
Body Image and Eating Disorder Concerns | CBS LA
Itai Danovitch, MD
3 Easy Ways to Reduce Stress When You Have IBS | Everyday Health
Brennan Spiegel, MD, MSHS
Los Angeles Schools Limit Classroom Screen Time Amid Concerns About Child Development | Consumer Affairs
Jane Tavyev Asher, MD
How Will the Commanders Replace Laremy Tunsil—and Could He Return This Season? | The New York Times
Brian Lee, MD
Warning Symptoms, Clinical History Can Predict Sudden Cardiac Arrest | HealthDay
Sumeet Chugh, MD
Inconclusive BRCA Results Linked to Higher Breast Cancer Risk | Medscape
Fahima Dossa, MD, PhD
How Urinary Tract Infections Trigger Delirium in People With Dementia | Being Patient
Shouri Lahiri, MD
Faculty Publications
Biomedical Sciences
Let Distortion-Guided Restoration: A Physics-Informed Learning Framework to Correct Prostate Diffusion MRI Artifacts. Long, Ziyang, Nader Binesh, Lixia Wang, Archana Vadiraj Malaji, Chia-Chi Yang, Haoran Sun, Rola Saouaf, Timothy Daskivich, Hyung Kim, Yibin Xie, Debiao Li, and Hsin-Jung Yang. Radiology Advances 3 (4): umag031.
Metabolic Reprogramming of Brain Microglia: Implications for Aging and Aging-Associated Neurodegenerative Diseases. Kang, Seokjo, and Helen S. Goodridge. Aging Cell 25 (8): e70660.
Nepal’s Vulnerability to Nipah Virus Transmission: An Urgent Call for Preparedness. Lama, Bhupendra, Uday Narayan Yadav, Gopiram Syangtan, Alaka Bhandari, Binod Gc, Mukesh Rai, Martyn D. Kirk, and Binod Rayamajhee. Sustainable Microbiology 3 (2): qvag015.
Cardiac Surgery
A New Era for the Surgical Treatment of Atrial Fibrillation: Evolving Surgical Techniques and Clinical Considerations. Kiankhooy, Armin, Adam Eqbal, Richard P. Whitlock, T. Jared Bunch, Ali J. Khiabani, Ralph J. Damiano, Graham Peigh, Rod S. Passman, Patrick M. McCarthy, J. Hunter Mehaffey, and Arnar Ingason. The Annals of Thoracic Surgery, August, S0003-4975(26)00817-9.
Baseline Lung Allograft Dysfunction: Definition, Timing, and Implications for Outcomes-an ISHLT Consensus Document. Gottlieb, Jens, Tereza Martinu, Merel Hellemons, David R. Darley, Laurie Snyder, Laura DiChiacchio, Miranda Paraskeva, Christian Benden, Berta Saez-Gimenez, Anoop Mohandas, Letizia Corinna Morlacchi, Joshua M. Diamond, Saskia Bos, Erika D. Lease, Geert Verleden, Allan Glanville, and Kieran Halloran. The Journal of Heart and Lung Transplantation, June, S1053-2498(26)01945-5.
Donor Diabetes Status Impacts Long-Term Survival in Diabetic Heart Transplant Recipients. Lim, Brian, Allen A. Razavi, Aminah Sallam, Vikram Krishna, Federico Sertic, Dominic Emerson, Dominick Megna, Pedro Catarino, Michael E. Bowdish, Lawrence Czer, Jon Kobashigawa, Fardad Esmailian, Joanna Chikwe, and Laura DiChiacchio. JHLT Open 14 (November): 100631.
Cardiology
Aspirin-Free P2Y12 Inhibitor Monotherapy Post-Stenting in Acute Coronary Syndromes. Kaul, Sanjay, and James M. Brophy. European Heart Journal, August, ehag620.
Dual Inhibition of SGLT 1 and 2 by Sotagliflozin Alleviates Intracellular Sodium Overload and Improves Cardiometabolic Remodelling in Uraemic Cardiomyopathy. Young, Megan, Anja Karlstaedt, Sanushi Dambure, Jack J. J. J. Miller, Tong Guo, Xin Zhou, Zenouska Ramchunder, Jair Gonzalez Marques Junior, Muriel Nobles, Andrew Tinker, Kyuongmin Kim, Amanda R. Purcell, Sarah J. Glastras, Fenn Cullen, Thomas R. Eykyn, Alex Von Kriegsheim, Blanca Rodriguez, Michelangelo Campanella, Michael J. Shattock, Nay Aung, Claudia P. Cabrera, Magdi M. Yaqoob, and Dunja Aksentijevic. Cardiovascular Research, August, cvag167.
Prediction of Left Main Coronary Artery Disease by ECG Exercise Stress Testing: Ready for Clinical Implementation? Bairey Merz, C. Noel. European Heart Journal, August, ehag605.
Predictors of Target Lesion Failure in Patients With In-Stent Restenosis: Insights From the AGENT IDE Trial. Abbott, J. Dawn, Nicholas Kassis, Azeem Latib, Richard A. Shlofmitz, Jeffrey W. Moses, William B. Bachinsky, Suhail Dohad, Steven G. Rudick, Robert C. Stoler, Brian K. Jefferson, William J. Nicholson, John D. Altman, Cinthia T. Bateman, Amar Krishnaswamy, Rafael Cavalcante, Robert W. Yeh, and Ajay J. Kirtane. Circulation. Cardiovascular Interventions, August, e016289.
The Current and Future in Transcatheter Treatment of Aortic Stenosis: From the ‘Beyond the Guidelines’ Session at Cardiovascular Research Technologies. Ha, Edward T., Holger Thiele, Michael Joner, Howard C. Herrmann, Hasanian A. Jilaihawi, Gilbert H. L. Tang, Isaac George, Thomas E. MacGillivray, and Ron Waksman. Cardiovascular Revascularization Medicine: Including Molecular Interventions, July, S1553-8389(26)00326-X.
Computational Biomedicine
Impact of Surveillance Colonoscopy on Colorectal Cancer Incidence and Mortality in Lynch Syndrome: A National Observational Cohort Study of Patients in the English NHS 2010-2022. Huntley, Catherine, Lucy Loong, Corinne Mallinson, Tameera Rahman, Beth Torr, Sophie Allen, Isaac Allen, Hend Hassan, Yvonne Walburga Joko Fru, Daniela Tataru, Lizz Paley, Sally Vernon, Richard S. Houlston, David Muller, Fiona Lalloo, Adam C. Shaw, John Burn, Eva J. A. Morris, Marc Tischkowitz, Antonis C. Antoniou, Paul D. P. Pharoah, Kevin Monahan, Steven Hardy, and Clare Turnbull. Gut, August, gutjnl-2025-337379.
Emergency Medicine
Conversational Artificial Intelligence and Neuropsychiatric Risk: A Narrative Review and Case-Based Synthesis Proposing a Delusional Feedback Loop. Abesadze, Nino, Abigale Fernandes, and Elizabeth Rubin. Cureus 18 (7): e112306.
Small Doses, Big Problems: Antidote Shortages. Laub, Daniel Ascher, Maryann Mazer-Amirshahi, Michelle Burns, and Erin R. Fox. The Journal of Pediatric Pharmacology and Therapeutics: JPPT, 31 (4): 574–76.
Imaging
Coronary Plaque Phenotype in Ischemic Stroke Survivors: A Quantitative Coronary CT Angiography Comparison With Acute Myocardial Infarction and Stable Chest Pain. Muthalaly, Rahul G., Julian Giovannucci, Andrew Lin, Sean Tan, Nitesh Nerlekar, Adam J. Nelson, Damini Dey, Thanh Phan, Henry Ma, and Stephen J. Nicholls. Radiology. Cardiothoracic Imaging 8 (4): e260039.
Medicine
Association Between Diabetic Control and Progression of Monoclonal Gammopathy of Undetermined Significance to Multiple Myeloma. Liu, Lawrence, Byron Sigel, Mei Wang, Nikhil Grandhi, Martin W. Schoen, Kristen M. Sanfilippo, Kenneth R. Carson, Murali Janakiram, Tzeyu L. Michaud, Graham A. Colditz, Theodore S. Thomas, and Su-Hsin Chang. Blood Cancer Journal 16 (1): 135.
Association of High Birth Weight With Risk of Early-Onset Colorectal Cancer. Mukherjee, Amrita, Lanfang Xu, Darios Getahun, Jessica Chubak, Jane C. Figueiredo, Kimberly L. Cannavale, Alec D. Gilfillan, Bechien U. Wu, and Chun R. Chao. Cancer Epidemiology, Biomarkers & Prevention: A Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology, August.
Belzutifan Plus Lenvatinib Versus Cabozantinib in Patients With Previously Treated Advanced Renal Cell Carcinoma (LITESPARK-011): An Open-Label, Randomized, Controlled, Phase 3 Trial. Motzer, Robert J., Ray McDermott, Se Hoon Park, Mauricio Burotto, Roberto Iacovelli, Elena Verzoni, Cristina Suárez, Masatoshi Eto, Hernan J. Cutuli, Camillo Porta, Ray Manneh Kopp, Sylvie Rottey, Guillermo de Velasco, Begoña P. Valderrama, Arun A. Azad, Ugo De Giorgi, Michel Pavic, Piotr Tomczak, Robert Figlin, Hans M. Westgeest, Annalisa Guida, Andrea Necchi, Fabio A. Schutz, Britt B. M. Suelmann, John B. A. G. Haanen, Sammy Shuai Yuan, Rodolfo F. Perini, Ding Wang, Daniel Y. C. Heng, Manuela Schmidinger, and LITESPARK-011 Investigators. Lancet, August, S0140-6736(26)01089-5.
Beyond Calprotectin: Where Leucine-Rich Α2-Glycoprotein May Fit in Small Bowel Crohn Disease Monitoring. Anand, Rajsavi, and Andres J. Yarur. Inflammatory Bowel Diseases, August, izag165.
Early Consideration of Automated Insulin Delivery in Type 2 Diabetes: A Critical Review. Tariq, Zunera, Grazia Aleppo, Anders L. Carlson, David Kayne, Davida F. Kruger, Yogish C. Kudva, Eden Miller, Katelyn O’Brien, Sean M. Oser, Ruth S. Weinstock, and Viral N. Shah. Endocrine Practice, August, S1530-891X(26)01105-5.
Fstl1 Determines Luminal Size of Mouse Trachea Through Negative Regulation of BMP4 Signaling. Jin, Yueyue, Yue Zhang, Yingying Liu, Maolin Yao, Chenjie Zhang, Shuzi Li, Yibo Ding, Zhuan Niu, Yue Han, Yan Geng, Lian Li, Xue Liu, and Wen Ning. iScience 29 (8): 116972.
Liver Transplantation at the Extreme: Analysis of Outcomes and Predictors of Futility in Acute-on-Chronic Liver Failure Grade 3 Patients on Maximal Life Support. Melehy, Andrew, Asara Thepbunchonchai, Benjamin V. Tran, Ruben Hernaez, Dominic Amara, Samer Ebaid, Daniela Markovic, Fady M. Kaldas, Igor Barjaktarevic, Victor Xia, Constantine J. Karvellas, Saro Khemichian, Lance L. Stein, Kirti Shetty, Christina C. Lindenmeyer, Justin R. Boike, Douglas A. Simonetto, Robert S. Rahimi, Prasun K. Jalal, Manhal Izzy, Michael S. Kriss, Gene Y. Im, Ming V. Lin, Janice H. Jou, Brett E. Fortune, George Cholankeril, Alexander Kuo, Vinay Sundaram, Multi-Organ Dysfunction and Evaluation for Liver Transplantation (MODEL) Consortium, Ronald W. Busuttil, Douglas G. Farmer, and Vatche G. Agopian. JHEP Reports: Innovation in Hepatology, August, 101959.
Novel Topical Treatment for Dysgeusia/Ageusia: A Case Series Report. Epstein, Joel B., Arezou Petrie, Geena L. Epstein, and Andrei Barasch. Supportive Care in Cancer, 34 (9): 845.
STAT3 Signaling Inhibitors for Cancer Treatment. Akinsola, Rasaq, Jing Xian, and James Turkson. Trends in Pharmacological Sciences, August, S0165-6147(26)00173-2.
Neurosurgery
Cross-Region Neuron Co-Firing Mediated by Ripple Oscillations Supports Distributed Working Memory Representations. Verzhbinsky, Ilya A., Jonathan Daume, Sophia Cheng, Ueli Rutishauser, and Eric Halgren. Nature Neuroscience, August.
Dorsal Spinal CSF Leaks in Patients With Spontaneous Intracranial Hypotension: A Radiologic-Anatomic Study. Schievink, Wouter I., Marcel M. Maya, Kim T. Giang, Rachelle B. Taché, Ravi S. Prasad, and Vikram Wadhwa. AJNR. American Journal of Neuroradiology, August, ajnr.A9572.
Inferring Brain-Wide Interactions Using Data-Constrained Recurrent Neural Network Models. Perich, Matthew G., Charlotte Arlt, Sofia Soares, Siyan Zhou, Manuel Beiran, Aaron S. Andalman, Tyler Benster, Megan E. Young, Clayton P. Mosher, Juri Minxha, Eugene Carter, Ueli Rutishauser, Peter H. Rudebeck, Christopher D. Harvey, Karl Deisseroth, and Kanaka Rajan. Neuron, August, S0896-6273(26)00571-4.
Orthopaedics and Sports Medicine
Achilles Tendon Injuries in Major League Soccer: A 10-Year Analysis of Injury Rate, Return to Play, and Performance Metrics. Forsythe, Brian, Catherine Hand, Francis Hand, Henry Eilen, Matthew Varano, Jared Sasaki, Camden Bohn, Anne Timmermann, Lauren Fertig, Eric Giza, Robert H. Brophy, Bert Mandelbaum, and Kirk McCullough. Orthopaedic Journal of Sports Medicine 14 (8): 23259671261449641.
Smart Implantable Device Use Is Associated With Decreased Post-Discharge Hospital Utilization in Total Knee Arthroplasty Patients Who Have Metabolic Syndrome: A Propensity Score-Matched Analysis. Nakla, Andrew, Patrick M. Aubin, Samuel Ademisoye, Rebecca G. Burr, Sean S. Rajaee, and Mark Wu. The Journal of Arthroplasty, August, S0883-5403(26)00843-0.
Pathology and Laboratory Medicine
Reproductive Factors and Brain Volume in Community-Dwelling Individuals: The Ohasama Study. Saito, Ayana, Kyoko Nomura, Michihiro Satoh, Satoshi Yamaguchi, Azusa Hara, Melanie Griffith-Quintyne, Hiroaki Shimizu, Shingo Nakayama, Megumi Tsubota-Utsugi, Takahisa Murakami, Yukako Tatsumi, Takuo Hirose, Tomoko Totsune, Naoko Mori, Kei Asayama, Masahiro Kikuya, Hirohito Metoki, Atsushi Hozawa, and Takayoshi Ohkubo. Environmental Health and Preventive Medicine 31: 52.
Unmasking Additional Mutations: A Single Institution Study in Myeloproliferative Neoplasms. Tizro, Parastou, Eric Vail, Manoj Sapkota, Matthew G. Gayhart, and Celeste C. Eno. Cancers 18 (15): 2458.
Pediatrics
Alemtuzumab Induction via Intravenous vs. Subcutaneous Administration in Pediatric Kidney Transplantation. Pizzo, H., A. Barbera, K. Westreich, M. E. Seifert, J. Mirocha, K. Kirshner, and D. Puliyanda. Pediatric Transplantation 30 (8): e70424.
Whole Genome Sequencing in Cerebral Palsy: A UK Paediatric Pilot Study. Ratnaike, Thiloka E., Heather H. Pierce, Alison J. Coffey, Joao M. L. Dias, Iain R. L. Kean, Emily Li, Ravi P. More, Dulika S. Sumathipala, Maya Bajracharya, Zoya Kingsbury, Taksina Newington, Anthony S. Rogers, Isabelle Delon, Kate Downes, Yasmin de Alwis, Anna P. Basu, Manal Issa, Catherine Kearney, Amjad H. Khan, Benjamin P. Marlow, Alison Sansome, JooWook Ahn, A. Yee Than, Tracy Lau, David R. Bentley, Sarah Bowdin, Evan Reid, Henry Houlden, Sean Humphray, and David H. Rowitch. The Lancet Regional Health. Europe 68 (September): 101786.
Surgery
‘I Don’t like Fitting a Box, Except the Box I Am’: Genderqueer and Nonbinary (GQNB) Patient Strategies for Navigating Healthcare. Sidhu, Shanaya, Jennifer T. Anger, Victor Trasvina, Falisha Kanji, Kyle Okamuro, Sunny Mangiameli, Alan J. Card, Tara Cohen, Hanna J. Barton, and TRANS-SAFE Author Group. International Journal for Equity in Health 25 (1): 194.
Incidental Mass Found on Screening Colonoscopy. Amedi, Alan, Serhat Suzer, Jesse Zuckerman, and Eiman Firoozmand. Journal of Surgical Case Reports 2026 (8): rjag684.
Prediction of Blunt Trauma Outcomes With Pulmonary Contusion Quantification. Jain, Ashwin, Erik DiGiacomo, Pedro V. Staziaki, Matthew Diamond, Donghoon Shin, Celina L. Duran, Oam Bhate, Myoung Jin Kim, Stephan W. Anderson, Tejal S. Brahmbhatt, and Christina A. LeBedis. Emergency Radiology, August.
Predictive Models for Toxicities after CAR T-Cell Therapy: Challenges and Opportunities. Ma, Julie, August Culbert, Tian-Gen Chang, Mark L. Solter, Eytan Ruppin, Kai Rejeski, and Nirali N. Shah. Blood Cancer Discovery, August, OF1–23.
Reply to: When Guidelines Meet Reality: Implementing the 2025 ATA Recommendations for Differentiated Thyroid Cancer in Limited-Resource Settings. Ho, Allen S., Matthew D. Ringel, Julie Ann Sosa, Julie H. Johnson, and Ellen Marqusee. Thyroid, August, 10507256261478396.
Surviving the Nucleus Pulposus Desert: Next-Generation Strategies for Intervertebral Disc Cell Therapy. Hamidouche, Tynhinane, Namdev More, Tiffany Lee, Mia Orr, Anne Camus, Devina Purmessur, Sarah E. Gulbrand, Nadeen O. Chahine, Lara Silverman, and Dmitriy Sheyn. JOR Spine 9 (3): e70207.
The Thyroid Cancer Modified Anxiety Scale (TC-MAX): Development and External Validation of a Thyroid Cancer Distress Instrument. Bastien, Amanda J., Sungjin Kim, Cynthia Zalt, Iris Cong, Jewel Ng, Caroline Marshall, Christopher V. Almario, Omer Liran, Brennan M. R. Spiegel, Jon Mallen-St Clair, Evan S. Walgama, Kevin S. Scher, Julie K. Jang, Yufei Chen, Samuel Zhang, Gary Bloom, Michelle M. Chen, K. Linnea Peterson, Wendy L. Sacks, Zachary S. Zumsteg, and Allen S. Ho. Thyroid, August, 10507256261475819.
Urology
How Low Do You Need to Go? Association Between Various Prostate-Specific Antigen Response Measures and Clinical Outcomes in Metastatic Castration-Sensitive Prostate Cancer in the Veterans Health Administration Data. Freedland, Stephen J., Wei Gao, Maëlys Touya, Hongbo Yang, David Russell, Jingyi Chen, Grace Chen, and Jasmina I. Ivanova. Cancer 132 (16): e70494.
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