Faculty Publications April 3-10

This week’s edition of Faculty Publications includes Cedars-Sinai studies that were published April 3-10. If you have a published paper from this period that does not appear on this list, please contact Sue Marone.

Cedars-Sinai in the News

New Study Finds an AI’s Clinical Decisions Rivaled Doctors | Forbes
Caroline Goldzweig, MD 

Cedars-Sinai Surgeons Embrace the Power of Robot-Assisted Surgeries | Spectrum News
Philip Brazio, MD 

Her Upbringing and Training Shaped This Doctor's View of Infections and Vaccines | American Heart Association
Priya Soni, MD

Ambient AI Sets the Stage for Clinical Decision Support | HealthLeaders
Yaron Elad, MD 

The Diagnostic Use of Skin Biopsy in Parkinson’s Disease and Other Synucleinopathies: Background, Supporting Evidence, and Controversies | World Parkinson’s Conference Blog
Michele Tagliati, MD 

A New Threat to Cardiovascular Health: Climate Change, Extreme Weather and Wildfires | American College of Cardiology
Janet Wei, MD

New Strategy Brings Substance Abuse Treatment Into the Hospital | HealthLeaders
Itai Danovitch, MD; Jeffrey Golden, MD 

Cómo Saber si Consumes Suficiente Proteína en 3 Pasos | La Opinión
Albert Abayev, RD

Faculty Publications

Biomedical Sciences

Examining Explicit Stereotype Perceptions of Colorectal Cancer Screening and Diagnosis in the Hispanic Community. Foley, Aidan, Bianca Luna-Lupercio, Jessica M. Capaldi, Galen Wiens-Cook, Vinicius Calsavara, Zulfikarali Surani, Sarah-Jeanne Salvy, Jane C. Figueiredo, Robert Haile, Nenette A. Cáceres, and Celina H. Shirazipour. Journal of Cancer Education, March.

Targeting SCD Triggers Lipotoxicity of Cancer Cells and Enhances Anti-Tumor Immunity in Breast Cancer Brain Metastasis Mouse Models. Sammarco, Alessandro, Giorgia Guerra, Katharina M. Eyme, Kelly Kennewick, Yu Qiao, Joelle El Hokayem, Kevin J. Williams, Baolong Su, Cagri Cakici, Hayk Mnatsakanyan, Valentina Zappulli, Steven J. Bensinger, and Christian E. Badr. Communications Biology 8 (1): 562.

Cardiology

Association of Double-Blind Reviews With Increases in Women as First Authors: An Initial Report From the Journal of Cardiac Failure. Defilippis, Ersilia M., Elena Donald, Logan Cho, Andrew Sauer, Jennifer Maning, Vanessa Blumer, Alexander Hajduczok, Quentin Youmans, Martha Gulati, Meredith T. Hurt, Alayna Humphrey, Nosheen Reza, Robert Mentz, and Anuradha Lala. Journal of Cardiac Failure 31 (3): 592–97.

F-18 Flurpiridaz Positron Emission Tomography Myocardial Perfusion Imaging Combined With Treadmill Exercise Testing. Bourque, Jamieson M., Rob S. B. Beanlands, Daniel S. Berman, and Panithaya Chareonthaitawee. Journal of Nuclear Cardiology, 45S (March): 102170.

Effects of Evolocumab on Coronary Plaque Composition and Microcalcification Activity by Coronary PET and CT Angiography. Han, Donghee, Evangelos Tzolos, Rebekah Park, Heidi Gransar, Mark Hyun, John D. Friedman, Sean W. Hayes, Louise E. J. Thomson, Alan C. Kwan, Matthew Budoff, Prediman K. Shah, Jacek Kwieciński, Sarah Wetzel, Chloe Findling, Piotr J. Slomka, Damini Dey, Balaji K. Tamarappoo, and Daniel S. Berman. JACC. Cardiovascular Imaging, March, S1936-878X(25)00090-7.

A Survey of National Practice Patterns of Hepatocellular Carcinoma Surveillance for Patients With Fontan-Associated Liver Disease: A Call to Action. Kappus, Matthew R., Dempsey Hughes, Daniel Ganger, Yuli Kim, Mustafa Bashir, Julie Bonn, Amir Borhani, David Fetzer, Ryan Fischer, Helena Gabriel, Maha Guindi, Elizabeth Hecht, Maarouf Hoteit, Geetika Khanna, Richard Krasuski, Sara Lewis, Alisha Mavis, Frank Miller, Cara Morin, Thomas Schiano, Gary Schooler, Alexandra Shingina, Claude Sirlin, Amit Singal, Bachir Taouli, Rose Tompkins, Ali Zaidi, Lisa VanWagner, and Takeshi Yokoo. Liver Transplantation, April.

Aortic Valve Replacement for Asymptomatic Severe Aortic Stenosis: Is Enthusiasm Exceeding the Evidence? Kaul, Sanjay. Journal of the American College of Cardiology 85 (14): 1511–14.

Intracoronary Acetylcholine for Vasospasm Provocation in Women With Ischemia and No Obstructive Coronary Artery Disease. Tjoe, Benita, Christine Pacheco, Nissi Suppogu, Bruce Samuels, Panteha Rezaeian, Balaji Tamarappoo, Daniel S. Berman, Behzad Sharif, Michael Nelson, R. David Anderson, John Petersen, Carl J. Pepine, Louise E. J. Thomson, C. Noel Bairey Merz, and Janet Wei. American Heart Journal Plus: Cardiology Research and Practice 53 (May): 100527.

Computational Biomedicine

A Disease-Specific Language Model for Variant Pathogenicity in Cardiac and Regulatory Genomics. Zhan, Huixin, Jason H. Moore, and Zijun Zhang. Nature Machine Intelligence, March, 1–11.

OnSIDES Database: Extracting Adverse Drug Events From Drug Labels Using Natural Language Processing Models. Tanaka, Yutaro, Hsin Yi Chen, Pietro Belloni, Undina Gisladottir, Jenna Kefeli, Jason Patterson, Apoorva Srinivasan, Michael Zietz, Gaurav Sirdeshmukh, Jacob Berkowitz, Kathleen LaRow Brown, and Nicholas P. Tatonetti. Med (New York, N.Y.), March, 100642.

Clinician and Patient Perspectives on a Patient-Facing Online Breast Cancer Symptom Visualization Tool. Gresham, Gillian, Michael Luu, N. Lynn Henry, Tyra Nguyen, Katherine Barnhill, Greg Yothers, Sungjin Kim, Andre Rogatko, Deanna J. Attai, Mourad Tighiouart, Ron D. Hays, and Patricia A. Ganz. JCO Clinical Cancer Informatics 9 (April): e2400109.

Rethinking GWAS: How Lessons From Genetic Screens and Artificial Intelligence Could Reveal Biological Mechanisms. Hazelett, Dennis J. Bioinformatics (Oxford, England), April, btaf153.

Global Applicability of a Risk Prediction Tool for Sentinel Node Positivity in Patients With Primary Cutaneous Melanoma. Lo, Serigne N., Caroline Gjorup, Annette Hougaard Chakera, Lisbet Rosenkrantz Hölmich, Marc Moncrieff, Alastair MacKenzie Ross, Oliver Cassell, Jiawen Ma, Marie Brinch-Møller Weitemeyer, Roger Olofsson Bagge, Siri Klausen, Vinicius F. Calsavara, João P. Duprat Neto, Eduardo Bertolli, Sydney Ch’ng, Robyn P. M. Saw, Kerwin F. Shannon, Andrew J. Spillane, Omgo E. Nieweg, Jonathan R. Stretch, Graham J. Mann, Jenny L. C. Geh, Lauren E. Haydu, Richard C. W. Martin, Cimarron Sharon, Giorgos C. Karakousis, Mohammed Kashani-Sabet, George Adigbli, Mary-Ann El Sharouni, Jeffrey E. Gershenwald, Richard A. Scolyer, John F. Thompson, and Alexander H. R. Varey. JAMA Dermatology, April.

Medicine

Spiritual Care in Outpatient Oncology: A Qualitative Study of Focus Groups With Cancer Center Chaplains. White, Kelsey B., Petra J. Sprik, Bronwen Jones, and George Fitchett. Supportive Care in Cancer 33 (4): 322.

S-Adenosylmethionine Deficit Disrupts Very Low-Density Lipoprotein Metabolism Promoting Liver Lipid Accumulation in Mice. Luque-Urbano, María R., David Fernández-Ramos, Fernando Lopitz-Otsoa, Virginia Gutiérrez de Juan, Maider Bizkarguenaga, Lia Castro-Espadas, Uxue Hermoso-Martínez, Lucía Barbier-Torres, Shelly C. Lu, Oscar Millet, and José M. Mato. Journal of Lipid Research, April, 100794.

Renin-Angiotensin-Aldosterone System Inhibitor Use Improves Clinical Outcomes in Patients With Metabolic Dysfunction-Associated Steatotic Liver Diseases: Target Trial Emulation Using Real-World Data. Ng, Wee Han, Yee Hui Yeo, Hyunseok Kim, Ekihiro Seki, Jonathan Rees, Kevin Sheng-Kai Ma, Cynthia A. Moylan, Luz María Rodriquez, Manal Abdelmalek, Augusto Villanueva, Mazen Noureddin, and Ju Dong Yang. Hepatology (Baltimore, Md.), April.

Brain-Wide Mapping of Immune Receptors Uncovers a Neuromodulatory Role of IL-17E and the Receptor IL-17RB. Lee, Yunjin, Tomoe Ishikawa, Hyeseung Lee, Byeongjun Lee, Changhyeon Ryu, Irene Davila Mejia, Minjin Kim, Guangqing Lu, Yujin Hong, Mengyang Feng, Hyeyoon Shin, Sylvain Meloche, Richard M. Locksley, Ekaterina Koltsova, Sergei I. Grivennikov, Myriam Heiman, Gloria B. Choi, and Jun R. Huh. Cell, April, S0092-8674(25)00279-X.

Comparison of Initial Artificial Intelligence (AI) and Final Physician Recommendations in AI-Assisted Virtual Urgent Care Visits. Zeltzer, Dan, Zehavi Kugler, Lior Hayat, Tamar Brufman, Ran Ilan Ber, Keren Leibovich, Tom Beer, Ilan Frank, Ran Shaul, Caroline Goldzweig, and Joshua Pevnick. Annals of Internal Medicine, April.

Effect, Tolerability, and Safety of Exclusive Palatable Elemental Diet in Patients With Intestinal Microbial Overgrowth. Rezaie, Ali, Bianca W. Chang, Juliana de Freitas Germano, Gabriela Leite, Ruchi Mathur, Krystyna Houser, Ava Hosseini, Daniel Brimberry, Mohamad Rashid, Sepideh Mehravar, M. J. Villanueva-Millan, Maritza Sanchez, Stacy Weitsman, Cristina M. Fajardo, Ignacio G. Rivera, Joo Lijin, Yin Chan, Gillian M. Barlow, and Pimentel Mark. Clinical Gastroenterology and Hepatology, April, S1542-3565(25)00241-1.

Efficacy of Adjuvant Therapy in Patients With Stage IIIA Cutaneous Melanoma. Grover, P., S. N. Lo, I. Li, A. M. J. Kuijpers, F. Kreidieh, A. Williamson, T. Amaral, F. Dimitriou, J. Placzke, K. Olino, M. G. Vitale, P. Saiag, G. V. Long, et al. Annals of Oncology, April, S0923-7534(25)00132-2.

High Global Prevalence of Steatotic Liver Disease and Associated Subtypes: A Meta-Analysis. Kit Ho, Glenn Jun, Faith Xin Ning Tan, N. Apoorva Sasikumar, Ethan Kai Jun Tham, Donghyun Ko, Do Han Kim, Pojsakorn Danpanichkul, Zhenning Yu, Cheng Xianda, Zi Xuan Zhang, Karn Wijarnpreecha, Thanawin Pramotedham, Mazen Noureddin, Daniel Q. Huang, Yoshio Sumida, Atsushi Nakajima, Ming-Hua Zheng, Hirokazu Takahashi, Cheng Han Ng, and Mark Muthiah. Clinical Gastroenterology and Hepatology, April, S1542-3565(25)00242-3.

Long-Term Sustained Improvement in Unplanned Healthcare Utilization in Patients With Inflammatory Bowel Disease. Melmed, Gil Y., Brant Oliver, Alice Kennedy, Jason K. Hou, Donald Lum, Siddharth Singh, Welmoed K. van Deen, Ridhima Oberai, S. Alandra Weaver, James Testaverde, Corey A. Siegel, and IBD Qorus. The American Journal of Gastroenterology, April.

Opportunities and Challenges for MRD Assessment in the Clinical Management of Multiple Myeloma. Paiva, Bruno, Qian Shi, Noemi Puig, Maria-Teresa Cedena, Alberto Orfao, Brian G. M. Durie, Nikhil C. Munshi, and Jesús San-Miguel. Nature Reviews. Clinical Oncology, April.

Strategies for Sustaining Emergency Care in the United States. Abir, Mahshid, Brian Briscombe, Carl T. Berdahl, Kirstin W. Scott, Sydney Cortner, Daniel Wang, Rose Kerber, and Wilson Nham. RAND Corporation.

Endoscopic Sleeve Gastroplasty for the Treatment of Metabolic Syndrome: A Systematic Review and Meta-Analysis. Hanscom, Mark, Muhammad Usman Baig, Drew Wright, Laith Baqain, Kate Elise Johnson, Vivek Kumbhari, Shelby Sullivan, Barham Abu Dayyeh, SriHari Mahadev, Carolyn Newberry, Kartik Sampath, David Carr-Locke, Christopher Thompson, and Reem Sharaiha. Obesity Surgery, April.

EXPRESS: A British Understanding of Racialised Gaze-Cueing in the Context of Implicit Racial Bias, Explicit Racial Identity, and Self-Esteem. Ward, Makayla Zariah, Wieske van Zoest, and Ayoub Bouguettaya. Quarterly Journal of Experimental Psychology (2006), April, 17470218251335304.

Mechanisms of Gastroesophageal Reflux Post-Roux-En-Y Gastric Bypass: Universal Alteration of the Antireflux Barrier Is the Culprit. Abu Dayyeh, Barham K., Karim Al Annan, Razan Aburumman, Tala Abedalqader, Rudy Mrad, Khushboo Gala, Vitor Brunaldi, and Omar M. Ghanem. Surgical Laparoscopy, Endoscopy & Percutaneous Techniques, April.

The AKAP12-PKA Axis Regulates Lipid Homeostasis During Alcohol-Associated Liver Disease. Thimme Gowda, Chandana, Mallikarjuna Siraganahalli Eshwaraiah, Jiaohong Wang, Youngyi Lim, Maria Lauda Tomasi, Nirmala Mavila, and Komal Ramani. Signal Transduction and Targeted Therapy 10 (1): 109.

Neurosurgery

Consistent Hierarchies of Single-Neuron Timescales in Mice, Macaques and Humans. Zeisler, Zachary R., Marques Love, Ueli Rutishauser, Frederic M. Stoll, and Peter H. Rudebeck. The Journal of Neuroscience, April, e2155242025.

Harnessing Immune Rejuvenation: Advances in Overcoming T Cell Senescence and Exhaustion in Cancer Immunotherapy. Admasu, Tesfahun Dessale, and John S. Yu. Aging Cell, April, e70055.

OBGYN

Pegylated Liposomal Doxorubicin Does Not Affect Cardiac Function in Patients Treated for Gynecologic Malignancies. Levytska, Khrystyna, R. Wendel Naumann, Miranda J. Benfield, Jubilee Brown, Yovanni Casablanca, Brittany Lees, Allison M. Puechl, and Erin K. Crane. Gynecologic Oncology Reports 58 (April): 101727.

Orthopaedics

Lumbosacral Anatomy Is Unique in Pediatric Spondylolysis. Finkel, Ryan A., Nakul Narendran, Daniel Farivar, Paal Nilssen, Melodie F. Metzger, David L. Skaggs, and Kenneth D. Illingworth. Spine Deformity, April.

Humeral Development Throughout the Arc of Childhood-A 3D MRI Study. Lind, Paige M., Michael L. Pearl, Katharine E. Alter, Euan A. Forrest, and Frances T. Sheehan. Journal of Orthopaedic Research, April.

Pathology and Laboratory Medicine

Exploring the Potential of Selective FKBP51 Inhibitors on Melanoma: An Investigation of Their in Vitro and in Vivo Effects. Marrone, Laura, Valeria Di Giacomo, Chiara Malasomma, Marialuisa Alessandra Vecchione, Felix Hausch, Massimiliano Cacace, Lucia D’Esposito, Martina Tufano, Paolo D’Arrigo, Maria Fiammetta Romano, and Simona Romano. Cell Death Discovery 11 (1): 138.

Pediatrics

Eight Cases of Pediatric Acute-Onset Neuropsychiatric Syndrome With Inflammatory Bowel Disease: Immunologic Intersections. Tang, Angela W., Paula M. Prieto Jimenez, Ian K.T. Miller, Juliette C. Madan, Jaden Nguyen, Meiqian Ma, Melissa Silverman, Bahare Farhadian, Jenny Wilson, Alka Goyal, Cindy Manko, Yinka Davies, Shervin Rabizadeh, and Jennifer Frankovich. Developmental Neuroscience, February.

Physical Medicine & Rehabilitation

Value of Incident Reporting to Address Real-Time Safety Opportunities During the COVID-19 Pandemic. Roberts, Pamela S., Nandita Raman, Brandi Rico, and Edward Seferian. Journal of Patient Safety, April.

Case Report: Neuropsychological Profile of a Patient With Intravascular Large B-Cell Lymphoma Following Infection and Vaccination. Misterka, Justin D., Andrew Wong, Liorah Sabbah, Shant Rising, Ann Gottuso, and Jeffrey Wertheimer. Archives of Clinical Neuropsychology, April, acaf027.

Psychiatry & Behavioral Neurosciences

Schizophrenia Management: Systematic Review of Current Medications and Phase-3 Agents (2008–2024). Abdelmoteleb, Salma, Jayant Totlani, Salma Ramadan, Mohamed Salem, Ashley Meyer, Tiffany Chang, Madeline Ewing, Luiza Freire, Nathalie Murphy, Sabrina Renteria, Romana Dymkoski, Omer Liran, Rebecca Hedrick, Itai Danovitch, Robert N. Pechnick, and Waguih William IsHak. Neuroscience Applied 4 (January): 105507.

Anxiety Disorders, PTSD and OCD: Systematic Review of Approved Psychiatric Medications (2008–2024) and Pipeline Phase III Medications. Franklin, Hollie. Drugs in Context (blog). April 3.

Hospital Addiction Consultation Service and Opioid Use Disorder Treatment: The START Randomized Clinical Trial. Ober, Allison J., Cristina Murray-Krezan, Kimberly Page, Peter D. Friedmann, Jess Anderson, Karen Chan Osilla, Stephen Ryzewicz, Sergio Huerta, Mia W. Mazer, Randall A. Hoskinson, Richard Garvey, Alexandra Peltz, Katherine E. Watkins, Teryl Nuckols, Waguih William IsHak, Louis T. Mariano, and Itai Danovitch. JAMA Internal Medicine, April, e248586.

Surgery

Postmastectomy Radiation Therapy for Intermediate-Risk Breast Cancer Patients With 0-3 Positive Axillary Lymph Nodes: Emulating the SUPREMO Trial Using Real-World Data. Kulkarni, Sarah E., Sagar A. Patel, Chen Jiang, Lara Schwieger, Lauren M. Postlewait, Cletus A. Arciero, Theresa W. Gillespie, and Yuan Liu. Clinical Breast Cancer, March, S1526-8209(25)00066-7.

Progress and Challenges in Developing Allogeneic Cell Therapies. Deuse, Tobias, and Sonja Schrepfer. Cell Stem Cell 32 (4): 513–28.

Targeted Spiral Ganglion Neuron Degeneration in Parvalbumin-Cre Neonatal Mice. Nguyen, Nhi V., Joshua S. Lin, Miti J. Parikh, Raffaello M. Cutri, and Seiji B. Shibata. Molecular Therapy. Methods & Clinical Development 33 (2): 101440.

Urology

The Association Between Statin Use, Genetic Variation, and Prostate Cancer Risk. Amiri, Ali, Wei Xu, Qihuang Zhang, Jae H. Jeong, Stephen J. Freedland, Neil E. Fleshner, Antonio Finelli, and Robert J. Hamilton. Prostate Cancer and Prostatic Diseases, April.

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