Faculty Publications April 2-9
A Comprehensive Digest of Research Publications From Cedars-Sinai Investigators and a Sampling of Recent Media Coverage Featuring Faculty
This week’s edition of Faculty Publications includes Cedars-Sinai studies that were published April 2-9. If you have a published paper from this period that does not appear on this list, please contact Sue Marone.
Cedars-Sinai in the News
What, Exactly, Is Longevity Medicine? | The New York Times
James Kirkland, MD, PhD
This Week in Science: How Much Exercise You Need, Flu Resistance and Fortified Food | NPR
Eli Friedman, MD
Inside Luka Doncic’s High-Stakes Medical Treatment and Recovery Plan | Los Angeles Times
Kenton Fibel, MD
Adolescente Que Sufre Dramático Accidente en Bicicleta Motorizada Vive Para Contarla | La Opinión
Galinos Barmparas, MD; Romina Kim, MD
10 Brain Exercises That Could Help You Stay Sharp as You Age | Good Housekeeping
Zaldy Tan, MD, MPH
Fast Twitch vs. Slow Twitch Muscles: Here’s The Difference | Runner’s World UK
Joshua Scott, MD
The Digital Path to AI in Cancer Care | Inside Precision Medicine
Mohamed Omar, MD
Faculty Publications
Biomedical Sciences
DZ-1-Artesunate Conjugate Induces Mitochondria-Mediated, Reactive Oxygen Species-Dependent Apoptosis in Colorectal Cancer Tumoroids. Narayanasamy, Badrinath, Yi Zhang, Alexandra Gangi, Robert Figlin, Karine Sargsyan, Heuiran Lee, Cheryn Song, and Yong J. Lee. Frontiers in Pharmacology 17: 1743141.
Protectin DX Reduces Inflammatory Pain Initiated by Superoxide Anion in Mice: Targeting Leukocyte Recruitment, Oxidative Stress, Cytokine Production and TRPV1+ Nociceptive Sensory Neuron Activation. Carneiro, Jessica A., Beatriz H. S. Bianchini, Geovana Martelossi-Cebinelli, Nayara A. Artero, Thaila K. E. Maximiano, Anelise Franciosi, Amanda M. Dionisio, Kelly M. Yaekashi, Thacyana T. Carvalho, Matheus D. V. da Silva, Fernanda S. Rasquel-Oliveira, Janaína Menezes Zanoveli, Victor Fattori, Rubia Casagrande, and Waldiceu A. Verri. Inflammation Research, 75 (1): 87.
Vessel-Density Distribution Mapping on Portal Venous CT and Deep Learning for 2-Year Overall Survival Risk Stratification after Transarterial Chemoembolization in Hepatocellular Carcinoma. Wang, Chen, Yimeng He, Yufeng Wang, Zengtian Deng, Lixia Wang, and Debiao Li. Abdominal Radiology, April.
Cardiology
Adaptive Immune Response to the Autoantigen LL-37 Differentiates Atherosclerotic Cardiovascular Disease Phenotypes. Dimayuga, Paul C., Kuang-Yuh Chyu, Jianchang Zhou, Xiaoning Zhao, Janet Wei, Bojan Cercek, and Prediman K. Shah. Clinical & Translational Immunology 15 (3): e70083.
Disparities for Asian American Medical Students in Alpha Omega Alpha and Gold Humanism Honor Societies. Yang, David H., Mytien Nguyen, Lindy Zhang, Jiun-Ruey Hu, Simona C. Kwon, Stella S. Yi, Lan N. Ðoàn, David Henderson, Alexandra M. Hajduk, Sarwat I. Chaudhry, B. U. K. Li, and Dowin Boatright. JAMA Network Open 9 (4): e265168.
Women’s IschemiA TRial to Reduce Events in Non-ObstRuctive CAD (WARRIOR): A Randomised Controlled Trial. Pepine, Carl J., Eileen Handberg, Rhonda Cooper-DeHoff, Galen Cook-Wiens, Marcio A. Diniz, Susan Frayne, Margaret C. Lo, Steven M. Smith, Barbara Harris, Janet Wei, Bernard R. Chaitman, John A. Spertus, Colin Berry, William Weintraub, and C. Noel Bairey Merz. Open Heart 13 (1): e004115.
AI-Derived LA Volume Index, LA/RA and LA/LV Volume Ratios From Coronary Artery Calcium Scans Predict Long-Term Atrial Fibrillation and Stroke. Azimi, Amir, Kyle Atlas, Anthony P. Reeves, Chenyu Zhang, Jakob Wasserthal, Seyed Reza Mirjalili, Mohammadhossein Mozafarybazargany, Ali Hashemi, Thomas Atlas, Claudia I. Henschke, David F. Yankelevitz, Javier J. Zulueta, Andrea D. Branch, Sion K. Roy, Khurram Nasir, Sabee Molloi, Jamal S. Rana, Zahi A. Fayad, Michael V. McConnell, George S. Abela, Rozemarijn Vliegenthart, David J. Maron, Jagat Narula, Kim A. Williams, Prediman K. Shah, Matthew J. Budoff, Emelia J. Benjamin, Roxana Mehran, Robert A. Kloner, Nathan D. Wong, and Morteza Naghavi. Stroke, April.
Sex-Specific Prognostic Value of Aortic Valve Calcium and the Risk for Aortic Stenosis: Multi-Ethnic Study of Atherosclerosis (MESA). Marrero, Natalie, Kunal Jha, Jelani K. Grant, Alexander C. Razavi, Matthew J. Budoff, Sanjiv J. Shah, Jerome I. Rotter, Roger S. Blumenthal, Wendy S. Post, Martha Gulati, Leslee J. Shaw, George Thanassoulis, Michael J. Blaha, and Seamus P. Whelton. Circulation. Cardiovascular Imaging, April, e018849.
Computational Biomedicine
The Kids FACE FEARS Pragmatic Randomized Trial of Therapist-Led vs Guided Internet Cognitive Behavioral Therapy for Pediatric Anxiety: Rationale and Methods. Comer, Jonathan S., Donna B. Pincus, Molly C. Adrian, Gary McCreary, Leslie Miller, Tomas Munarriz, Kathleen Myers, Karen Xiomara Pierre-Louis, Rheanna Platt, Melissa K. Ripley, Andrea E. Spencer, Haniya Saleem Syeda, Margarita Alegría, Amelia Brandt, Carolina Costa, Lindsay Cooper, Stefany Coxe, Annie W. Dantowitz, Anthony Steven Dick, Alyssa M. Farley, Jami M. Furr, Alex E. Keller, Julia A. Lejeune, Lauren F. McLellan, Dana L. McMakin, Rachel A. Merson, Ricardo F. Muñoz, Ronald M. Rapee, Kendra L. Read, Sara Rivero-Conil, Bridget Poznanski, Michelin Jane Janvier, Hanan N. Salem, Philip Shumway, Jennifer Sikov, Michelle V. Porche, and Lisa R. Fortuna. JAACAP Open 4 (2): 373–98.
Reply to the Letter to the Editor: Variation in Prostate Cancer Growth Rates in an MRI-Based Active Surveillance Cohort. Smith, Hayley, Vasilis Stavrinides, Francesco Giganti, Caroline M. Moore, Bharath Narayanan, Mark Emberton, Paul D. P. Pharoah, and Nora Pashayan. European Radiology, April.
WebGWAS: A Web Server for Instant GWAS on Arbitrary Phenotypes. Zietz, Michael, Undina Gisladottir, Kathleen LaRow Brown, and Nicholas P. Tatonetti. BioData Mining, April.
Imaging
Surgical Exploration of Radiographically Resolved Spontaneous Ventral Spinal CSF Leaks. Schievink, Wouter I., Marcel M. Maya, Franklin G. Moser, Vikram Wadhwa, and Ravi S. Prasad. AJNR. American Journal of Neuroradiology 47 (4): 1141–46.
Medicine
Expert Consensus on Hyaluronic Acid Injections for Knee Osteoarthritis: A Patient-Centered Approach. Fuggle, Nicholas, François Rannou, Emmanuel Maheu, Alberto Migliore, Nasser Al-Daghri, Majed Alokail, Patrick Ammann, Francis Berenbaum, Angie Botto-van Bemden, Maria Luisa Brandi, Nansa Burlet, Roland Chapurlat, Cyrus Cooper, Elaine Dennison, Nicholas C. Harvey, Gun-Il Im, Andreas Kurth, Radmila Matijevic, Daniel Messina, Jordi Monfort Faure, Régis P. Radermecker, Ralf Schmidmaier, Stuart Silverman, Julien Wegrzyn, Leith Zakraoui, René Rizzoli, Jean-Yves Reginster, Olivier Bruyère, and Ali Mobasheri. Aging Clinical and Experimental Research, April.
Translating ctDNA Into Cutaneous Melanoma Care: An International Expert Survey. Geidel, Glenn, Nathan Fekade, Katharina Raabe, Daniel J. Smit, Laura Adam, Isabel Heidrich, Alessandra Rünger, Julian Kött, Tim Zell, Teresa Amaral, Paolo A. Ascierto, Pippa Corrie, Reinhard Dummer, Alexander Eggermont, Jun Guo, Jessica C. Hassel, Mathilde Jalving, Douglas B. Johnson, Lidija Kandolf, John M. Kirkwood, Celeste Lebbé, Rebecca Lee, Georgina V. Long, Paul Lorigan, Josep Malvehy, Joanna Mangana, Peter Mohr, Sapna P. Patel, Helen Rizos, Caroline Robert, Dirk Schadendorf, Vernon K. Sondak, Inge Marie Svane, Alberto Wainstein, Jonathan S. Zager, Klaus Pantel, Axel Hauschild, Christoffer Gebhardt, and Melanoma World Society Study Group. European Journal of Cancer 239 (March): 116676.
Comparative Efficacy of Phase 2-3 Therapies for Non-Cirrhotic Metabolic Dysfunction-Associated Steatohepatitis: An Updated Network Meta-Analysis. Tsutsumi, Tsubasa, Nicole Shu Ying Tang, Cheng Han Ng, Hiroyuki Suzuki, Nicholas L. Syn, N. Apoorva Sasikumar, Glenn Jun Kit Ho, Damien Chua, Jing Kai Tioh, Thanawin Pramotedham, Selvakumar Vigneshwaran, Peter Jin Sun Low, Joon Ho Moon, Dan Yock Young, Vincent Wai-Sun Wong, Ming-Hua Zheng, Carel W. Le Roux, Jörn M. Schattenberg, Weiting Ting Huang, Timothy J. Kendall, Jonathan A. Fallowfield, Vincent L. Chen, Hirokazu Takahashi, Mary E. Rinella, Mohammad Shadab Siddiqui, Mazen Noureddin, Arun J. Sanyal, Mark D. Muthiah, and Takumi Kawaguchi. Med, March, 101077.
Defining Disease or Delaying Care? A Conceptual and Clinical Appraisal of the Lancet Obesity Framework. Muniyappa, Ranganath, Tariq Chukir, Dimpi Desai, Michael A. Weintraub, Maureen D. Corrigan, Roma Gianchandani, and Amy E. Rothberg. The Journal of Clinical Endocrinology and Metabolism, April, dgag097.
Hyperglycemia During Acute Pancreatitis and Progression to Early-Onset Diabetes After Recovery: Preliminary Findings From the Diabetes Related to Acute Pancreatitis and Its Mechanisms (DREAM) Study. Dungan, Kathleen M., Vernon M. Chinchilli, Ariana Pichardo-Lowden, Nazia Raja-Khan, Melena D. Bellin, Dhiraj Yadav, Phil A. Hart, Marina Basina, James L. Buxbaum, Anna Casu, Carmella Evans-Molina, Darwin L. Conwell, Evan L. Fogel, Chris E. Forsmark, Mark O. Goodarzi, Rita R. Kalyani, Brian T. Layden, Sandra M. Lord, Georgios I. Papachristou, Walter G. Park, Richard Pratley, Vikesh K. Singh, Cate Speake, Guru Trikudanathan, Maren Laughlin, Frederico G. S. Toledo, and Type 1 Diabetes in Acute Pancreatitis Consortium (T1DAPC):*. Diabetes Care, April, dc252885.
Endovascular Coil Embolization Compared to Surgical Ligation of the Uterine Artery in a Non-Human Primate Model in a Model of Preeclampsia. Makris, A., N. Roshan, J. Iliopoulos, R. Waugh, A. Al-Hindawi, B. Corbett, C. C. Liu, B. Lian, S. Heffernan, J. Hyett, J. Ardui, S. Pears, S. A. Karumanchi, and A. Hennessy. Laboratory Animal Research 42 (1): 12.
GM-CSF Orchestrates Monocyte and Granulocyte Responses to Cryptococcus Gattii. Ricafrente, Alison, Sreemoyee Acharya, Shuyi Chen, Adiza Abass, Aelita Arshakyan, Tyler J. Olson, Apurwa Trivedi, and Lena J. Heung. PLoS Pathogens 22 (4): e1013418.
irAE-GPT: Leveraging Large Language Models to Identify Immune-Related Adverse Events in Electronic Health Records and Clinical Trial Datasets. Bejan, Cosmin A., Michelle Wang, Sriram Venkateswaran, Ewa A. Bergmann, Laura Hiles, Yaomin Xu, G. Scott Chandler, Sam Brondfield, Jordyn Silverstein, Francis Wright, Kimberly de Dios, Daniel M. Kim, Eric Mukherjee, Matthew S. Krantz, Lydia Yao, Douglas B. Johnson, Elizabeth J. Phillips, Justin M. Balko, Rajat Mohindra, and Zoe Quandt. EBioMedicine, April, 106227.
Association of Pharmacotherapy With All-Cause Mortality Among Patients With Irritable Bowel Syndrome. Mehravar, Sepideh, Yee Hui Yeo, Mark Pimentel, Parnian Naji, Wee Han Ng, Nils Burger, Will Takakura, and Ali Rezaie. Communications Medicine 6 (1): 176.
Monocyte Chemokines Enhance Atherosclerotic Plaque Necrosis After Bacterial Kidney Infection. Possenriede, Lena, Peyman Falahat, Marie Foerster, Georg W. Sendtner, Julia Miranda, Leonie Richard-Stropahl, Uta Scheidt, Christian Kurts, Florian Wagenlehner, Ekaterina K. Koltsova, and Sibylle von Vietinghoff. FASEB Journal, 40 (7): e71720.
Neurology
Safety and Feasibility of Transcranial Motor-Evoked Potentials During Intraoperative Neurophysiologic Monitoring in Patients With Deep Brain Stimulators. Meyers, Nicholas, Mark Keroles, Sungho Charles Cho, Rohit Gummi, Scheherazade Le, Leslie Lee, Viet Nguyen, Ankita Tippur, Jaime R. López, and Felix Chang. Journal of Clinical Neurophysiology, April.
Needs-Driven Simulation Education: Advancing Neuropalliative Communication for Neurology Residents. Makaroff, Katherine E., Alice Hawkins, Nathan Chu, Alex Aw, Jessica Besbris, Dan Karlin, and Cara Siegel. The American Journal of Hospice & Palliative Care, April, 10499091261440921.
Neurosurgery
Under Pressure: Advancing the Diagnosis of Pediatric CSF Leaks With Digital Subtraction Myelography. Garcia, Catherine M., Daniel Chang, Marcel M. Maya, Vikram S. Wadhwa, Ravi S. Prasad, Franklin G. Moser, and Wouter I. Schievink. AJNR. American Journal of Neuroradiology 47 (4): 1135–40.
Pediatric Sinogenic and Otogenic Intracranial Infections Requiring Neurosurgical Intervention: A North American Multicenter Study in the Era of COVID-19. Anderson, Megan G., Jonathan Pindrik, Ian C. Michelow, Amirul Anuar, Jared Haught, Hannah Lehmann, Tomoko Tanaka, Aidan Moore, Weston T. Northam, Carolina Lopes, Moise Danielpour, Catherine M. Garcia, David S. Hersh, et al. Journal of Neurosurgery. Pediatrics, April, 1–11.
Biportal Endoscopic Transorbital Approach With an Accessory Lateral Orbital Port for Anterior Petrosal Corridor: A Cadaveric Feasibility Study [Seven-004]. Choi, Seonah, Woo Hyun Kim, Soo Jeong Park, Tae Hoon Roh, Hong-Gyu Yoon, Chang-Ki Hong, and Je Beom Hong. Journal of Korean Neurosurgical Society, April.
OBGYN
Characteristics and Trends of Retracted Publications in Gynecologic Oncology. Levin, Gabriel, Lucy Gilbert, Rene Pareja, Reitan Ribeiro, Raanan Meyer, Bavitirra Ganesu, and Pedro T. Ramirez. International Journal of Gynecological Cancer, 36 (5): 104639.
Surgery
Beauty, Bias, and Beyond: The Role of Artificial Intelligence in Aesthetic Medicine. Knoedler, Samuel A., Michael Alfertshofer, Bruna S. F. Bravo, Giuseppe Sofo, Francesco Mazzarone, Robert Gaudin, Hermann F. Sailer, Alexandre G. Lellouch, and Leonard Knoedler. Journal of Cosmetic Dermatology 25 (4): e70853.
General Anesthetic Exposure in the Management of Pediatric Subglottic Stenosis. Koss, Kevin, Marvin S. Lu, Logan Massman, Karl Doerfer, and Thomas Robey. World Journal of Otorhinolaryngology - Head and Neck Surgery 12 (2): 211–17.
Urology
Costs of Care and Oncologic Outcomes Associated With Blue Light Cystoscopy in an Equal Access Setting: Results From the BRAVO Study. Nasrallah, Ali A., Claire Evans, Lin Gu, Joshua A. Parrish, Amanda M. De Hoedt, Jane Lapon, Chad McKee, William Aronson, Stephen J. Freedland, and Stephen B. Williams. Urologic Oncology, April, 111090.
Training Feedback Tailored to Technical Skills Expedites Proficiency in Performing Watertight Vesicourethral Anastomoses: A Randomized Controlled Trial. Dadashian, Eman, Peter Wager, Randy G. Tsai, Jonathan Varghese, Cherine Yang, Umar Ghaffar, John Heard, Eric Lo, Rikke Groth Olsen, Atharva Deo, Runzhuo Ma, Steven Cen, and Andrew J. Hung. Journal of Surgical Education 83 (5): 103937.
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