Faculty Publications April 10-17
A Comprehensive Digest of Research Publications From Cedars-Sinai Investigators and a Sampling of Recent Media Coverage Featuring Faculty
This week’s edition of Faculty Publications includes Cedars-Sinai studies that were published April 10-17. If you have a published paper from this period that does not appear on this list, please contact Sue Marone.
Cedars-Sinai in the News
New Approaches to Opioid-Free Pain Treatment | Nature Medicine
Brennan Spiegel, MD
This is the Frustrating Truth Behind Why Painkillers are Less Effective for Women | Huffington Post UK
Martha Gulati, MD
Cold Cap Therapy Prevents Hair Loss in Multiple Myeloma Patients | Oncology Times
Robert Vescio, MD
In-Hospital Addiction Consultations Put Opioid Users on Path to Recovery | HealthDay
Itai Danovitch, MD; Jeffrey Golden, MD
Elemental Diet Eases Symptoms in Microbiome Gastro Disorders | Medscape
Ali Rezaie, MD
Novel AI Algorithm Detects Liver Disease Via Cardiovascular Screenings | Healio Gastroenterology
Alan Kwan, MD
Understand the ROI of Clinical AI, Both Now and In the Future | HealthLeaders
Yaron Elad, MD
First 500 Patients in Align-AR Trial Using TAVR for Pure Aortic Regurgitation Show Strong Outcomes | Cardiovascular Business
Raj Makkar, MD
Faculty Publications
Anesthesiology
Preoperative Nutritional Risk Associations With Postoperative Morbidity and Mortality Following Elective Cardiac Surgery. Kumaresan, Abirami, George Gill, Tao Shen, Michael E. Bowdish, Joseph E. Ebinger, and Susan Cheng. Anesthesia and Analgesia 140 (5): 1239–41.
Cardiology
Prognostic Implications of Diabetes Insipidus in Heart Failure Hospitalizations: Insights From the U.S. National Readmissions Database 2016-2021. Menon, Lakshmi, Shubhadarshini Pawar, and Dileep Kumar Reddy Regalla. Journal of Clinical Medicine 14 (7): 2308.
Racial and Ethnic Differences in Long-Term Cardiovascular Mortality Among Women and Men From the CAC Consortium. Rosenblatt, Shmuel, Michael J. Blaha, Ron Blankstein, Khurram Nasir, Fay Lin, Yvette Yeboah-Kordieh, Daniel S. Berman, Michael D. Miedema, Seamus P. Whelton, John Rumberger, Matthew J. Budoff, Jonathon Leipsic, and Leslee J. Shaw. JACC. Cardiovascular Imaging, March, S1936-878X(25)00098-1.
A Chronology of Basic and Clinical Research in the Coronary Microcirculation. Chilian, William, Taha Ahmed, C. Noel Bairey Merz, Carl J. Pepine, Catherine Nicole Domingo, and Puja K. Mehta. Journal of Molecular and Cellular Cardiology, April, S0022-2828(25)00062-8.
AI-Enabled Opportunistic Measurement of Liver Steatosis in Coronary Artery Calcium Scans Predicts Cardiovascular Events and All-Cause Mortality: An AI-CVD Study Within the Multi-Ethnic Study of Atherosclerosis (MESA). Naghavi, Morteza, Kyle Atlas, Anthony Reeves, Chenyu Zhang, Jakob Wasserthal, Thomas Atlas, Claudia I. Henschke, David F. Yankelevitz, Javier J. Zulueta, Matthew J. Budoff, Andrea D. Branch, Ning Ma, Rowena Yip, Wenjun Fan, Sion K. Roy, Khurram Nasir, Sabee Molloi, Zahi Fayad, Michael V. McConnell, Ioannis Kakadiaris, David J. Maron, Jagat Narula, Kim Williams, Prediman K. Shah, George Abela, Rozemarijn Vliegenthart, Daniel Levy, and Nathan D. Wong. BMJ Open Diabetes Research & Care 13 (2): e004760.
Outcome Prediction After Tetralogy of Fallot Repair: A Prospective Clinical and Cardiovascular Magnetic Resonance Study. Wald, Rachel M., George Tomlinson, Christopher A. Caldarone, Nagib Dahdah, Frederic Dallaire, Christian Drolet, Michael E. Farkouh, Jasmine Grewal, Camille Hancock-Friesen, Edward J. Hickey, Gauri Rani Karur, Michelle Keir, Adrienne H. Kovacs, Benedetta Leonardi, Brian W. McCrindle, Syed Najaf Nadeem, Ming-Yen Ng, Michelle Samuel, Ashish Shah, Edythe B. Tham, Judith Therrien, Alexander Van De Bruaene, Isabelle F. Vonder Muhll, Andrew E. Warren, Kenichiro Yamamura, and Paul Khairy. Journal of the American Heart Association 14 (8): e039006.
Value of Artificial Intelligence for Enhancing Suspicion of Cardiac Amyloidosis Using Electrocardiography and Echocardiography: A Narrative Review. Grogan, Martha, Francisco Lopez-Jimenez, Spencer Guthrie, Nisith Kumar, Reuben Langevin, Isabelle Lousada, Ronald Witteles, Ajay Royyuru, Michael Rosenzweig, Sarah Cairns-Smith, and David Ouyang. Journal of the American Heart Association 14 (8): e036533.
Automated Deep Learning Phenotyping of Tricuspid Regurgitation in Echocardiography. Vrudhula, Amey, Milos Vukadinovic, Christiane Haeffele, Alan C. Kwan, Daniel Berman, David Liang, Robert Siegel, Susan Cheng, and David Ouyang. JAMA Cardiology, April.
Burden of Congenital Heart Anomalies in North Africa and the Middle East, 1990 to 2021: A Systematic Analysis for the Global Burden of Disease Study 2021. Soleimani, Hamidreza, Pegah Bahiraie, Kiarash Tavakoli, Negin Sadat Hosseini Mohammadi, Parisa Hajari, Homa Taheri, Kaveh Hosseini, and Pouya Ebrahimi. Journal of the American Heart Association, April, e037291.
Disparities in Achieving LDL-C Goals After Revascularization in a Diverse Real-World Cohort. Greenberg, Garred S., Daniel Lorenzatti, Annalisa Filtz, Vita N. Jaspan, Christine M. Park, Bethany Kalich, Niranjan Kathe, Eduard Sidelnikov, Katherine E. Di Palo, Constance Browne, Evan Lipsitz, Stephen Forest, Andrea Scotti, Azeem Latib, Mario J. Garcia, Carlos J. Rodriguez, Michael D. Shapiro, Martha Gulati, and Leandro Slipczuk. European Journal of Preventive Cardiology, April, zwaf235.
Sex Differences in the Association Between Lipoprotein(a) and Cardiovascular Outcomes: The MGB Lp(a) Registry. Kaur, Gurleen, Adam N. Berman, David W. Biery, Stephanie A. Besser, Wanda Y. Wu, Brittany Weber, Michael C. Honigberg, Khurram Nasir, Martha Gulati, Marcelo F. Di Carli, Leslee J. Shaw, Deepak L. Bhatt, and Ron Blankstein. Journal of the American Heart Association, April, e035353.
Computational Biomedicine
Perceptual and Technical Barriers in Sharing and Formatting Metadata Accompanying Omics Studies. Huang, Yu-Ning, Viorel Munteanu, Michael I. Love, Cynthia Flaire Ronkowski, Dhrithi Deshpande, Annie Wong-Beringer, Russell Corbett-Detig, Mihai Dimian, Jason H. Moore, Lana X. Garmire, T. B. K. Reddy, Atul J. Butte, Mark D. Robinson, Eleazar Eskin, Malak S. Abedalthagafi, and Serghei Mangul. Cell Genomics, April, 100845.
Medicine
Development of a 3D Bioengineered Human Lung Submucosal Gland Ductal Airway Model to Study Mucociliary Clearance in Vitro. Kim, Hoyeol, Sujung Yi, Pramodha Liyanage, Shuyang Zhao, Kathryn A. Wikenheiser-Brokamp, Lisa McMillin, Yan Xu, Joseph A. Kitzmiller, Jeffrey A. Whitsett, Anjaparavanda P. Naren, and Kyu Shik Mun. Cell Biomaterials 1 (2): 100013.
Rising Incidence of Early-Onset Liver Cancer and Intrahepatic Bile Duct Cancer: Analysis of the National Childhood Cancer Registry Database. Danpanichkul, Pojsakorn, Yanfang Pang, Thanida Auttapracha, Omar Al Ta’ani, Thanathip Suenghataiphorn, Apichat Kaewdech, Mark D. Muthiah, Donghee Kim, Karn Wijarnpreecha, Amit G. Singal, and Ju Dong Yang. Cancers 17 (7): 1133.
Exploring the Determinants of Treatment Completion Among Youth Who Received Medication-Assisted Treatment in the United States. Adeniran, Esther A., Megan Quinn, Ying Liu, Billy Brooks, and Robert P. Pack. Healthcare (Basel, Switzerland) 13 (7): 798.
Carvedilol Is Associated With Lower Risk of Hepatic Decompensation Compared to Other Non-Selective Beta-Blockers in Cirrhosis. Naik, Ilora, Yee Hui Yeo, Wee Han Ng, Kevin Sheng-Kai Ma, and Ju Dong Yang. Journal of Hepatology, April, S0168-8278(25)00232-6.
Large-Scale Multi-Omics Analyses in Hispanic/Latino Populations Identify Genes for Cardiometabolic Traits. Petty, Lauren E., Hung-Hsin Chen, Elizabeth G. Frankel, Wanying Zhu, Carolina G. Downie, Mariaelisa Graff, Phillip Lin, Priya Sharma, Xinruo Zhang, Alyssa C. Scartozzi, Rashedeh Roshani, Joshua M. Landman, Global Hispanic Lipids Consortium, et al. Nature Communications 16 (1): 3438.
Sex Disparities in Alcohol-Associated Liver Disease and Subtype Differences in Alcohol-Attributable Cancers in the United States. Danpanichkul, Pojsakorn, Yanfang Pang, Tanuj Mahendru, Primrose Tothanarungroj, Luis Antonio Díaz, Juan Pablo Arab, Pimtawan Jatupornpakdee, Mark D. Muthiah, Kwanjit Duangsonk, Won-Mook Choi, Daniel Q. Huang, Donghee Kim, Mazen Noureddin, Karn Wijarnpreecha, Suthat Liangpunsakul, Amit G. Singal, and Ju Dong Yang. Clinical and Molecular Hepatology, April.
Anti-Muscarinic 3 Antibodies Associate With a Severe Clinical Phenotype in Patients With Systemic Sclerosis. Ayla, Ali Y., Naveen R. Kalavar, Mark Pimentel, Walter Morales, Laura K. Hummers, Ami A. Shah, Michael Hughes, and Zsuzsanna H. McMahan. Rheumatology (Oxford, England), April, keaf197.
Implementation Outcomes of a Patient Decision-Aid in a Diverse Population With Systemic Lupus Erythematosus in 15 U.S. Rheumatology Clinics. Singh, Jasvinder A., Larry R. Hearld, Seth Eisen, W. Winn Chatham, Sonali Narain, Narender Annapureddy, Diane L. Kamen, Kimberly Trotter, Vikas Majithia, Cathy Lee Ching, Zineb Aouhab, Swamy Venuturupalli, Daniel J. Wallace, Rosalind Ramsey-Goldman, Alfred Kim, Maureen McMahon, S. Sam Lim, Kalpana Bhairavarasu, Alexa Meara, Kenneth Kalunian, Mark Beasley, and Implementing DEcision-Aid for Lupus in clinics (IDEAL) Consortium. Rheumatology (Oxford, England), April, keaf205.
Evolution of the Tumor Immune Landscape During Treatment With Tebentafusp, a T Cell Receptor-CD3 Bispecific. Sacco, Joseph J., Peter Kirk, Emma Leach, Alexander N. Shoushtari, Richard D. Carvajal, Camille Britton-Rivet, Sophie Khakoo, Laura Collins, Luis de la Cruz-Merino, Zeynep Eroglu, Alexandra P. Ikeguchi, Paul Nathan, Omid Hamid, Marcus O. Butler, Sarah Stanhope, Koustubh Ranade, and Takami Sato. Cell Reports. Medicine 6 (4): 102076.
Advances in Pregnancy Hypertension. Karumanchi, S. Ananth, and Jane F. Reckelhoff. Hypertension (Dallas, Tex.: 1979) 82 (5): 770–71.
Pathology and Laboratory Medicine
Proteinuria Trajectory and Disease Progression in Children and Adults With IgA Nephropathy/Vasculitis. Glenn, Dorey A., Ashley W. Carver, Margaret E. Helmuth, Abigail R. Smith, Richard A. Lafayette, Prasanth Ravipati, Andrea L. Oliverio, Dana V. Rizk, Jan Novak, Francesca Lugani, Sharon M. Bartosh, Krzysztof Mucha, Krzysztof Kiryluk, Manish K. Saha, Cynthia C. Nast, Jean Hou, Laura E. Biederman, Nidia Messias, Avi Z. Rosenberg, Heather N. Reich, Pietro A. Canetta, Patrick H. Nachman, Carla Nester, Raed Bou-Matar, Shikha Wadhwani, Laura H. Mariani, Myda Khalid, and CureGN IgA Working Group. Clinical Journal of the American Society of Nephrology: CJASN, April.
Psychiatry & Behavioral Neurosciences
Anxiety Disorders, PTSD and OCD: Systematic Review of Approved Psychiatric Medications (2008-2024) and Pipeline Phase III Medications. Tadros, Emile, Shirley Keerthana, Samar Padder, Jayant Totlani, Drew Hirsch, Daniel N. Kaidbay, Lorena Contreras, Aasim Naqvi, Samuel Miles, Krista Mercado, Ashley Meyer, Sabrina Renteria, Robert N. Pechnick, Itai Danovitch, and Waguih William IsHak. Drugs in Context 14: 2024-11–12.
Radiation Oncology
Development and Validation of an Artificial Intelligence Digital Pathology Biomarker to Predict Benefit of Long-Term Hormonal Therapy and Radiotherapy in Men With High-Risk Prostate Cancer Across Multiple Phase III Trials. Armstrong, Andrew J., Vinnie Y. T. Liu, Ramprasaath R. Selvaraju, Emmalyn Chen, Jeffry P. Simko, Sandy DeVries, Oliver Sartor, Howard M. Sandler, Osama Mohamad, Huei-Chung Huang, Jacqueline Griffin, Rikiya Yamashita, Andre Esteva, Phuoc T. Tran, Daniel E. Spratt, John Hi Carson, Christopher Peters, Elizabeth Gore, Steve P. Lee, Jedidiah M. Monson, Mark E. Augspurger, Ali El-Gayed, Joseph P. Rodgers, Rana McKay, Todd Morgan, Felix Y. Feng, and Paul L. Nguyen. Journal of Clinical Oncology, April, JCO2400365.
Surgery
American Association of Clinical Endocrinology Consensus Statement on Management of Multiple Endocrine Neoplasia Type 1. Del Rivero, Jaydira, Alexandra Gangi, Justin P. Annes, Sina Jasim, Jason Keller, Michelle D. Lundholm, Julie M. Silverstein, Tanaz M. Vaghaiwalla, and Robert A. Wermers. Endocrine Practice, March, S1530-891X(25)00038-2.
Fifth Metacarpal Neck Fractures: Less Is More. Zachary, Paige K. D., Harin B. Parikh, David A. Kulber, and Stuart H. Kuschner. Plastic and Reconstructive Surgery. Global Open 13 (4): e6687.
Angioembolization Within 60 Minutes for Exsanguinating Trauma Patients: A Meaningful Metric With a Definition Gap. Gao, Zihan, Nam Yong Cho, Aricia Shen, Nicholas Siena, Troy N. Coaston, Amulya Vadlakonda, Peyman Benharash, Galinos Barmparas, and Academic Trauma Research Consortium (ATRIUM). American Journal of Surgery 244 (April): 116338.
Robotic-Assisted Single-Port System for Pulmonary Lobectomy: A Prospective Feasibility Study. Zervos, Michael, Bernard J. Park, M. Blair Marshall, Jon O. Wee, Harmik O. Soukiasian, Matthew G. Hartwig, and David C. Rice. The Journal of Thoracic and Cardiovascular Surgery, April, S0022-5223(25)00293-4.
Outcomes of High Risk and Complicated Type B Aortic Dissections Treated With Thoracic Endovascular Aortic Repair. Filiberto, Amanda C., Zdenek Novak, Ali Azizzadeh, Jack L. Cronenwett, Joseph V. Lombardi, Grace Wang, Rodney White, Adam W. Beck, and TEVAR for Dissection Post-approval Project Steering Committee and Participants. European Journal of Vascular and Endovascular Surgery, April, S1078-5884(25)00332-6.
Early Thoracic Endovascular Aortic Repair for Acute Type B Dissection Is Associated With Increased Complications: Results From the GREAT Registry. Potter, Helen A., Charles C. Miller, Harleen K. Sandhu, Dennis R. Gable, Ali Azizzadeh, Cassra N. Arbabi, Santi Trimarchi, Fred A. Weaver, Hillary Alberta, and Gregory A. Magee. Annals of Vascular Surgery, April, S0890-5096(25)00229-8.
Functional Outcomes After Feminizing Rhinoplasty. Amin, Luv, Arthur W. Wu, and Henry H. Chen. Facial Plastic Surgery: FPS, April.
Pragmatic O-Positive Whole-Blood RandoMizaTion in Male Trauma Patients (POWeR-MTP). Strada, Anthony M., Gus Suarez, Xian Luo-Owen, Maryam B. Tabrizi, Martin G. Rosenthal, Wesley T. Stevens, Sharon S. Lum, and Kaushik Mukherjee. European Journal of Trauma and Emergency Surgery, 51 (1): 175.
Urology
Letter: Updates to Microhematuria: AUA/SUFU Guideline (2025). Chamie, Karim, Andrew Chen, Alejandro Rodriguez, and Wei Shen Tan. The Journal of Urology, April, 101097JU0000000000004553.
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