Articles tagged with 'heart research' & 'stem cell biology' | Cedars-Sinai Medical Center

Researchers have identified molecular changes that appear to trigger atherosclerosis years before inflammation—the long-recognized hallmark of the disease—takes hold, according to a Cedars-Sinai Health Sciences University-led study.The …

An investigational cell therapy preserved heart and muscle function in boys and young men with Duchenne muscular dystrophy, according to Phase III clinical trial results from Cedars-Sinai Health Sciences University investigators and colleagues …

The heart runs an around-the-clock fuel operation, burning almost any nutrient it can get to keep pumping. Understanding this fuel operation is the central focus of scientist Anja Karlstaedt, MD, PhD, and her team. Their work could lead to new …

Two studies from investigators at Cedars-Sinai Health Sciences University move the medical field closer to solving a longstanding challenge: predicting who is at risk for sudden cardiac arrest. “The majority of people who have a sudden cardiac …

Pregnancy is a window into a woman’s cardiovascular future, a new report shows.Smidt Heart Institute cardiologist Janet Wei, MD, is one of the authors of a maternal health report from the National Academies of Sciences, Engineering, and Medicine, a …

Younger people who experience sudden cardiac arrest are more likely to have a genetic cause than older people who experience it, according to new research from the Smidt Heart Institute at Cedars-Sinai. The study, published in JACC: Clinical …

A national study led by investigators from Cedars-Sinai Health Sciences University found that transcatheter tricuspid valve replacement, or TTVR, delivered strong early results in real-world practice. Patients treated with TTVR experienced near …

The heart’s ability to use oxygen efficiently is a critical indicator of its health, but tests to measure this function have drawbacks that can limit their use. A new Cedars-Sinai Health Sciences University study found that a new MRI system …

Susan Cheng, MD, MMSc, MPH, a clinician-scientist who has made seminal contributions to cardiovascular research and clinical care, has been appointed chair of the Department of Cardiology in the Smidt Heart Institute at Cedars-Sinai.Throughout …

The National Institutes of Health (NIH) and the National Institute on Aging have awarded a multi-institutional research team led by investigators in the Smidt Heart Institute at Cedars-Sinai $7.5 million to further study how damage to tiny blood …

What can a single molecule in just one of the body’s cells reveal about a person’s health? Quite a lot if you can find it. Cedars-Sinai investigators are doing just that.Using a powerful technology called single-cell proteomics, these detectives …

New scientific methods could one day render animal studies—the standard in research laboratories for more than 100 years—obsolete. Clive Svendsen, PhD, executive director of the Board of Governors Regenerative Medicine Institute at Cedars-Sinai, is …

An unusually high number of people developed a heart attack, lung complication or general illness within 90 days after the start of the January 2025 fires in Los Angeles, a new study from Cedars-Sinai reports. “Wildfires that spread into urban areas …

The California Institute for Regenerative Medicine (CIRM) has awarded Cedars-Sinai researchers more than $20 million to study potential treatments for heart failure and an inherited type of heart disease.CIRM, a taxpayer-funded state …

Cedars-Sinai scientists have developed an experimental drug that repairs DNA and serves as a prototype for a new class of medications that fix tissue damage caused by heart attack, inflammatory disease or other conditions.Investigators describe the …

Investigators from Cedars-Sinai and other institutions have created the largest artificial intelligence-based model for analyzing and producing reports from echocardiograms, ultrasound images doctors often use to diagnose heart disease. Their study, …

People who underwent a minimally invasive procedure to have their heart’s aortic valve replaced had similar health outcomes years after treatment as people who had surgery, Cedars-Sinai investigators and colleagues report.Raj Makkar, MD, an …

Patients with mouth injuries from trauma or surgery, or those requiring dental work to fix receding gums, could potentially have new options in the future, thanks to a study launching at Cedars-Sinai Guerin Children’s.The researchers will use stem …

Cedars-Sinai has been awarded $26 million to study whether open-heart surgery or a minimally invasive procedure has better outcomes in people born with a common heart condition.Led by interventional cardiologist Raj Makkar, MD, the …

Although cardiovascular disease is a leading cause of death for women, they remain underrepresented in clinical trials for common heart conditions. These findings, by investigators in the Smidt Heart Institute at Cedars-Sinai, were presented at the …

“Young” immune cells created by Cedars-Sinai investigators reversed signs of aging and Alzheimer’s disease in the brains of laboratory mice, according to a study published in the journal Advanced Science. The immune cells, which were produced from …

Cedars-Sinai investigators are aiming to transform stem cells into the first heart and brain organoids to be created in space. Their experiments will travel aboard a mission to the International Space Station that is scheduled to lift off from the …

The Cedars-Sinai Board of Governors Regenerative Medicine Institute launched the Cedars-Sinai Center for Space Medicine Research on May 22—and marked the occasion with a visit from NASA astronaut and microbiologist Kate Rubins, PhD.“The Center for …

A new study conducted at Cedars-Sinai reveals how the cholesterol-reducing drug evolocumab prevents heart attacks in people with coronary artery disease—a leading cause of death in the United States.Coronary artery disease occurs when cholesterol …

Three cardiovascular experts in the Smidt Heart Institute at Cedars-Sinai received distinguished American College of Cardiology (ACC) and Journal of the American College of Cardiology (JACC) awards during the ACC’s Annual Scientific Session on March …

A scientific technique that rapidly increases the body’s production of anti-inflammatory cells promoted healing from heart attacks in mice, according to a new study by investigators from the Smidt Heart Institute at Cedars-Sinai. Once adapted to …

An artificial intelligence (AI) program can identify chronic liver disease from videos taken during a common heart test known as an echocardiogram, Cedars-Sinai investigators report.  “Incorporating AI into echocardiograms, which capture images …

A multidisciplinary team of Cedars-Sinai investigators has used a novel single-cell proteomics approach to better understand the differences between naturally occurring adult heart cells and heart cells derived from induced pluripotent stem cells. …

Catherine Jayasuriya thought it was strange her then-6-year-old son, Dusty Brandom, seemed to fall down more often than other children and couldn’t keep up with his siblings. That year, 1998, Jayasuriya took Dusty to several doctors, one of …

A unique protein designed by Cedars-Sinai Cancer investigators can cross the protective blood-brain barrier safely and deliver therapy directly into cancerous tumor cells, a preclinical study shows. The findings, which could help clinicians target …