Faculty Publications Sept. 15-20

This week’s edition of Faculty Publications includes Cedars-Sinai studies that were published Sept. 15-20. If you have a published paper from this period that does not appear on this list, please contact Sue Marone. Studies published later in the week will be included in the next issue of Faculty Publications.

Cedars-Sinai in the News

71-Year-Old Is Thankful for Cedars-Sinai HIV-Positive Organ Transplant Program | CBS Los Angeles
Irene Kim, MD

Misplaced Glasses, Forgotten Names. How To Know When To Worry, and How To Thrive | Los Angeles Times
Zaldy Tan, MD, MPH 

Smoke From Wildfires Is a Growing Health Threat to Both People and Birds | Audubon Magazine
Susan Cheng, MD, MPH

We Asked 3 Cardiologists What They Eat Every Day for Better Heart Health | Verywell Health
Eli Friedman, MD

Map of Brain ‘Microproteins’ Could Offer New Clues to Alzheimer’s Disease | Nature
Bahareh Ajami, PhD 

4 Endocrinologists Share the Fruits They Eat Regularly for Better Blood Sugar | Verywell Health
Ruchi Mathur, MD 

ASTRO Issues Its First Clinical Guideline on Radiation Therapy for Bladder Cancer | The ASCO Post
Leslie Ballas, MD 

Extensively Drug-Resistant Shigella Emerges in US, Mostly Among Men | Healio Infectious Disease News
Ali Rezaie, MD

We Asked a Doctor When You Should Get Your First Bone Density Scan | Verywell Health
Natasha Trentacosta, MD 

Plant-Based Diet Linked to Lower Risk of Prostate Cancer Progression on Active Surveillance | The ASCO Post
Adam Weiner, MD 

What Low Vaccination Rates Could Mean for Flu Season 2026 | The San Fernando Valley Sun
Michael Ben-Aderet, MD

Faculty Publications

Biomedical Sciences

Artificial Intelligence-Derived Splenic Response in Cardiac Positron Emission Tomography Is Associated With Major Adverse Cardiovascular Events: A Multi-Site Study. Ramirez, Giselle, Naga L. Dharmavaram, Aakash Shanbhag, Robert J. H. Miller, Paul B. Kavanagh, Jirong Yi, Mark Lemley, Valerie Builoff, Anna Marcinkiewicz, Damini Dey, Jon Hainer, Samuel Wopperer, Stacey Knight, Viet T. Le, Steve Mason, Erick Alexanderson, Isabel Carvajal-Juarez, René R. S. Packard, Thomas L. Rosamond, Mouaz H. Al-Mallah, Leandro Slipczuk, Mark I. Travin, Wanda Acampa, Andrew J. Einstein, Panithaya Chareonthaitawee, Daniel S. Berman, Marcelo F. Di Carli, and Piotr J. Slomka. Cardiovascular Research, September, cvag184.

Beyond the Field of View: Radiomics and Artificial Intelligence for Organ-Specific and Systemic Disease Prediction From Localized Medical Imaging. Wang, Lixia, Yu Shi, Zengtian Deng, Yufeng Wang, Dante Rigo De Righi, Sehrish Javed, Touseef Ahmad Qureshi, Ju Dong Yang, Yibin Xie, Stephen J. Pandol, and Debiao Li. Artificial Intelligence in Medicine 182 (September): 103535.

Cardiac Surgery

Combination of Genetic eNOS Deficiency and High-Fat Diet Induces Reproducible Cardiometabolic HFpEF. Elbatreek, Mahmoud H., Vinayak Khodade, Darshan Amin, Miguel Huerta, Timothy D. Allerton, David J. Polhemus, Sanjiv J. Shah, Thomas M. Vondriska, Traci T. Goodchild, and David J. Lefer. Redox Biology 97 (September): 104394.

Plasma Angiotensin Levels and Postoperative Hypotension in Patients With and Without Chronic Heart Failure Undergoing Cardiac Surgery. DiChiacchio, Laura, Rana Hamouche, Eleni Maneta, Forest Riekhof, Stavros G. Drakos, Craig H. Selzman, and Thomas C. Hanff. ASAIO Journal, September.

Towards Individual Risk Stratification in ECMO-Bridged Heart Transplantation. Nammalwar, Shruthi, Robert Schultz, and Laura DiChiacchio. The Annals of Thoracic Surgery, September, S0003-4975(26)00930-6.

Cardiology

Author Response to ‘Persistent Proteomic Signatures in Takotsubo Syndrome: Methodological Considerations Regarding Reference Cohort Selection and Confounding.’ Marano, Paul, Jennifer E. Van Eyk, and C. Noel Bairey Merz. Journal of Cardiovascular Translational Research 19 (1): 117.

Avoid It or Reach It? The Cardiac Conduction Axis as a Common yet Divergent Determinant of Patient Outcomes in Transcatheter Aortic Valve Replacement and Conduction-System Pacing. Jilaihawi, Hasan, Kenneth A. Ellenbogen, Pugazhendhi Vijayaraman, and Raj R. Makkar. Heart Rhythm, September, S1547-5271(26)02774-8.

Deep Learning-Enabled Screening of Chronic Kidney Disease From Echocardiography. Yuan, Victoria, Hirotaka Ieki, Alexander Sandhu, Long H. Nguyen, Paul P. Cheng, Stephanie T. Chang, Andrew P. Ambrosy, Alan C. Kwan, Alan S. Go, Susan Cheng, and David Ouyang. Med, September, 101296.

Influence of Chronic Kidney Disease on Outcomes After Paclitaxel-Coated Balloon Angioplasty for Coronary In-Stent Restenosis. Tehrani, Behnam N., Ilan Vavilin, Richard Shlofmitz, Jeffrey Moses, William Bachinsky, Suhail Dohad, Steven Rudick, Robert Stoler, Brian K. Jefferson, William Nicholson, John Altman, Cinthia Bateman, Jennifer A. Tremmel, J. Dawn Abbott, Wayne Batchelor, Rafael Cavalcante, Robert W. Yeh, and Ajay J. Kirtane. Circulation. Cardiovascular Interventions, September, e016978.

Left Atrial Appendage Closure or Anticoagulation for Atrial Fibrillation. Reply. Doshi, Shephal K., and Saibal Kar. The New England Journal of Medicine 395 (11): 1140.

Lost in CLARIFY-Cation: The Sex Gap That Refuses to Close. Gulati, Martha, and C. Noel Bairey-Merz. European Journal of Preventive Cardiology, September, zwag488.

Mitral Valve Lithotripsy With SmartCrack Balloon for Severe Calcified Mitral Stenosis: First-in-Human Experience. So, Kent Chak-Yu, Kevin Ka-Ho Kam, Ling Na Geri Wong, Wang Hei Anselm Hui, Ching-Wei Lee, Tawai Ngernsritrakul, Leo Kar Lok Lai, Simon Chow, Shing Fung Chui, Michael Lee, Albert K. M. Chan, Randolph Wong, Thomas Modine, Hasan Jilaihawi, Yat-Yin Lam, Dee Dee Wang, Bryan Yan, and Alex Pui-Wai Lee. Journal of the American Heart Association, September, e050755.

Prognostic Implications of Functional Significance, High-Risk Plaque and Vessel Characteristics in Patients With Diabetes Mellitus. Song, Jin-Eun, Seokhun Yang, Masahiro Hoshino, Taishi Yonetsu, Jinlong Zhang, Eun-Seok Shin, Joon-Hyung Doh, Chang-Wook Nam, Jianan Wang, Shaoliang Chen, Nobuhiro Tanaka, Hitoshi Matsuo, Takashi Kubo, Hyuk-Jae Chang, Tsunekazu Kakuta, and Bon-Kwon Koo. The Korean Journal of Internal Medicine 41 (5): 873–83.

Computational Biomedicine

A FAIR Gold-Standard Benchmark for Geographic Entity Recognition in Cancer Genomics Literature for Biomedical NLP. Kann, Maricel G., Karen O’Connor, Petra Tembei, Samuel Rosner, and Graciela Gonzalez Hernandez. Bioinformatics Advances 6 (1): vbag225.

Ambient Air Pollutant Mixtures in Relation to Sonographic Endometrial Receptivity Parameters During the Peri-Implantation Window: A Clinic-Based Observational Study. Xu, Heze, Zhijiao Wang, Huixin Zhan, Yijia Liu, Shanwei Xing, Zekai Bai, Jingshuang Zhou, Hang Zhen, Jiapo Li, and Chong Qiao. Environmental Research, September, 125682.

Type 1 Interferon Perturbates Clonal Competition by Reshaping Human Blood Development. Lama, Chhiring, Danielle Isakov, Shira Rosenberg, Miguel Quijada-Álamo, Mirca S. Saurty-Seerunghen, Sara Moein, Mathis Nozais, Tsega-Ab Abera, Olivia Sakaguchi, Mansi Totwani, Grace Freed, Leila Zaydon, Chi-Lam Poon, Neelang Parghi, Andrea Kubas-Meyer, Amy X. Xie, Mohamed Omar, Daniel Choi, Franco Castillo-Tokumori, Ghaith Abu-Zeinah, Alicia Dillard, Saravanan Ganesan, Nathaniel D. Omans, Neville Dusaj, Paulina Chamely, Eleni Mimitou, Peter Smibert, Heidi E. Kosiorek, Amylou C. Dueck, Rona Weinberg, Ronan Chaligne, Bridget Marcellino, Luigi Marchionni, Sanjay Patel, Paul Simonson, Dan A. Landau, Elvin Wagenblast, Ronald Hoffman, and Anna S. Nam. Nature Genetics, September.

Medicine

Balancing Lipid Synthesis and Oxidation Promotes B Cell Response to Vaccination During Immunosuppression. Thompson, Elizabeth A., Alexis Figueroa, Katerina Roznik, Nicole E. Skinner, Santosh Dhakal, Shuai Li, Luca Biavati, Laura A. Sena, Laila Stoddart, Karli Redinger, Samuel B. Warner, Sabra L. Klein, Nadine Rouphael, Joel N. Blankson, Yolanda Eby, Robert D. Leone, Peter S. Heeger, Mark A. Robien, Christian P. Larsen, Erika L. Pearce, Edward J. Pearce, Hongkai Ji, Andrew H. Karaba, Dorry L. Segev, Aaron Ar Tobian, William A. Werbel, Andrea L. Cox, and Justin R. Bailey. The Journal of Clinical Investigation, September, e205170.

Clinical Scenarios of Suboptimal Response to Rituximab in Relapsing ANCA-Associated Vasculitis. Prieto-González, Sergio, Ellen Romich, Peter A. Merkel, David R. W. Jayne, Rona M. Smith, RITAZAREM investigators, and RITAZAREM investigators. Frontiers in Medicine 13: 1874867.

Global Disparities in Access to Randomized Controlled Trials for Pulmonary Arterial Hypertension. Khan, Dilawar, and Yuri Matusov. Respiratory Medicine, September, 109165.

Proportional Limb Strengths Signal an Adaptive Shift in Arboreality in Early Human Evolution. Carlson, Kristian J., Christopher B. Ruff, M. Loring Burgess, Adam D. Sylvester, Tea Jashashvili, Jason L. Heaton, Travis R. Pickering, Lauren Sarringhaus, Timothy M. Ryan, Amélie Beaudet, Robin H. Crompton, A. J. Heile, Dominic Stratford, Kathleen Kuman, David Lordkipanidze, and Ronald J. Clarke. Science Advances 12 (38): eaeh1752.

Specific Targeting of Cancer Cell Mitochondria With a Malaria Drug Improves Pancreatic Cancer Outcome. Ou, Yan, Adrian Lim, Ruoxiang Wang, Nora Mir, Vinicius F. Calsavara, Qiang Wang, Yi Zhang, Stephen J. Pandol, and Mouad Edderkaoui. Scientific Reports 16 (1): 28708.

Taking a Spiritual History in the Oral Oncology Setting. Santos-Silva, Alan Roger, Marco Magalhaes, Camila Barcellos Calderipe, Marcio Ajudarte Lopes, Eric V. Ávila-Pires, and Joel B. Epstein. Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer 34 (10): 989.

Neurology

Kit-Based Remote Collection and Isolation of Human Reprogrammable Somatic Cells for Generation of Induced Pluripotent Stem Cells and Cerebral Organoids. Cheng, Iris Q., Juan F. Ruiz, Evan K. Casalino, Ce Zhang, and Angeliki Louvi. Nature Protocols, September.

Orthopaedics and Sports Medicine

Advancements in Managing Bone Defects With Limb Length Discrepancies With a Motorized Intramedullary Combined Transport and Lengthening Nail. Collins, Angela C., and Geoffrey S. Marecek. Journal of Orthopaedic Trauma 40 (10S): S7–12.

Clinical Outcomes and Complications of the Posterior Dynamic Distraction Device in Adolescent Idiopathic Scoliosis: A Systematic Review and Meta-Analysis. Lam, Chuck H., Alma Sato, Halil Ibrahim Bulut, Jonathan Gibson, Conor T. Boylan, Jwalant S. Mehta, and Morgan Jones. European Spine Journal: Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, September.

History, Physical Examination, and Terminology of Osteochondral Lesions of the Talus: Proceedings of the International Congress on Cartilage Repair of the Ankle. Tham, Alexander, James J. Butler, Jared Rubin, Christiaan J. A. van Bergen, Onno L. Baur, Christopher D. Murawski, Pietro Spennacchio, Dominic Carreira, Stephen R. Kearns, Adam W. Mitchell, Helder Pereira, Christopher Pearce, Members of International Consensus Group on Cartilage Repair of the Ankle 2017*, et al. Foot & Ankle Specialist, September, 19386400261485355.

Scheuermann’s Kyphosis Carries Higher Perioperative Risk Than Idiopathic Scoliosis in Adolescent Patients Undergoing Posterior Spinal Fusion. Chan, Vivien, Justin L. Reyes, Monerah Annaim, Mehdi Elfilali, Michael G. Vitale, David L. Skaggs, and Zeeshan M. Sardar. Spine Deformity, September.

Pathology and Laboratory Medicine

Advancing Digital Health in Low-Middle-Income Countries: Experiences From Armenia’s Health System Digital Transformations. Sargsyan, Tsaghkanush, Anna Artsruni, Sergey Sargsyan, Ruzanna MoVsesyan, Arpine Muradyan, Avet Manukyan, and Karine Sargsyan. Frontiers in Public Health 14: 1827775.

Pediatrics

Circulating Tumor DNA Profiling Defines Risk Classification in Patients With Ewing Sarcoma: A Report From the Children’s Oncology Group and the LEOPARD Study. Shulman, David S., Kelly Klega, Nan Chen, Allen Buxton, Elliot Gohn, Sarah Sexton, Catherine Clinton, Mohammad Tanhaemami, Carrie Cibulskis, Edwin Choy, Thomas Cash, Kris Ann P. Schultz, Leo Mascarenhas, Rochelle Bagatell, Christopher Kuo, Brian K. Turpin, Bhuvana A. Setty, Bradley D. DeNardo, Douglas S. Hawkins, Michael W. Bishop, Avanthi Tayi Shah, Luke D. Maese, Julia L. Glade Bender, Damon Reed, Mark D. Krailo, Natalie DelRocco, Wendy B. London, Katherine A. Janeway, Steven G. DuBois, and Brian D. Crompton. Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology, September, JCO2600285.

Development of CRISPR_SCD001, an Autologous Hematopoietic Stem Cell Gene Therapy for Sickle Cell Disease After CRISPR-Cas9 Mediated Correction. DeWitt, Mark, Beatriz Campo-Fernandez, Sohini Roy, Alissa L. W. Kleinhenz, Alejandra Davila, Mallory Lennon, Jonnathan T. Vu, Netravathi Krishnappa, Suzanne Said, Chin-Hong Tseng, So Hyun Park, Gang Bao, Wendy Magis, David I. K. Martin, Dario Boffelli, Stacia K. Wyman, Donald B. Kohn, Mark C. Walters, and Zulema Romero. Molecular Therapy: The Journal of the American Society of Gene Therapy, September, S1525-0016(26)00790-2.

Diagnosis Through Whole Genome Sequencing and Care Utilization in Children With Severe Illness. Dias, Joao M. L., Ravi P. More, Duncan Butler, Julian Brown, Courtney E. French, Helen Dolling, F. Lucy Raymond, David H. Rowitch, and Catherine E. Aiken. JAMA Network Open 9 (9): e2634372.

Use of Purified Cannabidiol in Treatment-Resistant Pediatric Epilepsy: Beyond Lennox-Gastaut Syndrome, Dravet Syndrome, and Tuberous Sclerosis Complex. Kahan, Madeline D., Tiffany Lin, Sucheta M. Joshi, Elizabeth Hagopian, My H. Vu, Michele Van Hirtum-Das, Latanya D. Agurs, and Deborah L. Holder. Pediatric Neurology 184 (August): 101–5.

Radiation Oncology

Radiation Therapy for Bladder Cancer: An ASTRO Clinical Practice Guideline. Ballas, Leslie K., Abhishek A. Solanki, Brian C. Baumann, Piet Dirix, Comron Hassanzadeh, Nicholas G. Zaorsky, Andrea B. Apolo, Ananya Choudhury, Peter W. Chung, Jeffrey M. Holzbeierlein, Monika Joshi, Michele M. Kim, Cheryl T. Lee, William Moroney, Chad R. Ritch, Hina Saeed, Rituraj Upadhyay, Antoine G. van der Heijden, Lisa Bradfield, Amanda R. Helms, and Jason A. Efstathiou. Practical Radiation Oncology, September, S1879-8500(26)00273-0.

Surgery

Acute Cholecystitis in High-Risk Patients: A Systematic Review, Meta-Analysis, and Practice Management Guideline From the Eastern Association for the Surgery of Trauma (EAST). Ratnasekera, Asanthi, Rishi Rattan, Bishwajit Bhattacharya, Zugui Zhang, Madison Harris, Sirivan S. Seng, Connor Magura, Christopher A. Butts, Judy Rabinowitz, Jordan Michael Kirsch, Ida Molavi, Haytham Kaafarani, Tejal S. Brahmbhatt, Michael W. Cripps, Nikolay Bugaev, and John J. Como. Trauma Surgery & Acute Care Open 11 (3): e002191.

Beyond the First Cancer: Secondary Malignancies Associated With Soft Tissue Sarcomas. Nguyen-Thai, Allison, Farin Amersi, Alexandra Gangi, and Allan W. Silberman. The American Surgeon, September, 31348261472869.

Dual Acellular Subnormothermic Machine Perfusion for Enhanced Uterus Preservation in a Swine Model. Cabanel, Lucile, Haïzam Oubari, Bradley W. Ellis, Ludivine Dion, Vincent Lavoué, Carla Sousa, Loïc Van Dieren, Olivier Morel, Mark A. Randolph, Curtis L. Cetrulo, Korkut Uygun, Alexandre G. Lellouch, Yanis Berkane, and Basak E. Uygun. Acta Obstetricia Et Gynecologica Scandinavica, September.

Is There a Difference in the Outcomes of Long-Term Seton Placement for Complex Anal Fistula in Patients With and Without Crohn’s Disease? Aviran, Eyal, Dan Assaf, Karen Zaghiyan, and Phillip Fleshner. American Journal of Surgery 262 (September): 117248.

Long-Term Surveillance After EVAR and TEVAR: Are Patients Truly Lost to Follow-Up? Schwieger, Lara, Steven Scarlett, Mohyee Ayouty, Marvin Lu, Donna Bahroloomi, Cassra Arbabi, Navyash Gupta, Donald Baril, Ali Azizzadeh, and Elizabeth L. Chou. Annals of Vascular Surgery, September, S0890-5096(26)00654-0.

Resource Utilization and Outcomes of Inpatient Eyelid Reconstruction in Facial Palsy Patients: A 20-Year HCUP-NIS Study. Hoch, Cosima C., Tobias Niederegger, Emre Karakas, Douglas Henderson, Thomas Schaschinger, Dilan Gucuk, Christian Festbaum, Jakob Fenske, Alexandre G. Lellouch, Leonard Knoedler, and Andreas Kehrer. JPRAS Open 52 (November): 415–24.

Urology

ATP-Dependent Chromatin Remodelers in Prostate Cancer Progression and Therapeutic Resistance. Torres, Lillian M., Clayton Yates, Charlotte L. Bevan, Michael R. Freeman, and Moray J. Campbell. Endocrinology, September, bqag103.

Is Gleason Pattern 3 Cancer? Molecular Features Do Not Distinguish Pattern 3 From Benign Tissue. Leni, Riccardo, Scott E. Eggener, Matthew R. Cooperberg, Simpa S. Salami, Adam B. Weiner, Ming Zhou, Hasan Al-Sattar, Alastair D. Lamb, and Andrew J. Vickers. BJU International, September.

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