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02
September
2022
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Faculty Publications: Aug. 25-Sept. 1

A Comprehensive Digest of Research Publications From Cedars-Sinai Investigators

This week’s edition of Faculty Publications includes Cedars-Sinai studies that were published Aug. 25-Sept. 1. If you have a published paper from this period that does not appear on this list, please contact Sue Marone, who will add it to next week’s collection.

Biomedical Sciences 

KLF5 Governs Sphingolipid Metabolism and Barrier Function of the Skin. Lyu, Ying, Yinglu Guan, Lisa Deliu, Ericka Humphrey, Joanna K. Frontera, Youn Joo Yang, Daniel Zamler, Kun Hee Kim, Vakul Mohanty, Kevin Jin, Vakul Mohanty, Virginia Liu, Jinzhuang Dou, Lucas J. Veillon, Shwetha V. Kumar, Philip L. Lorenzi, Yang Chen, Kathleen M. McAndrews, Sergei Grivennikov, Xingzhi Song, Jianhua Zhang, Yuanxin Xi, Jing Wang, Ken Chen, Priyadharsini Nagarajan, and Yejing Ge. Genes & Development, August.

Production of MHCII-Expressing Classical Monocytes Increases During Aging in Mice and Humans. Barman, Pijus K., Juliana E. Shin, Sloan A. Lewis, Seokjo Kang, Di Wu, Yizhou Wang, Xiaoming Yang, Prakash S. Nagarkatti, Mitzi Nagarkatti, Ilhem Messaoudi, Bérénice A. Benayoun, and Helen S. Goodridge. Aging Cell, August, e13701.

Cancer

Targeted Long-Read Bisulfite Sequencing Identifies Differences in the TERT Promoter Methylation Profiles Between TERT Wild-Type and TERT Mutant Cancer Cells. Lee, Seungjae, Ti-Cheng Chang, Patrick Schreiner, Yiping Fan, Neeraj Agarwal, Charles Owens, Reinhard Dummer, John M. Kirkwood, Raymond L. Barnhill, Dan Theodorescu, Gang Wu, and Armita Bahrami. Cancers 14 (16): 4018.

Coffee Consumption and Risk of Endometrial Cancer: A Pooled Analysis of Individual Participant Data in the Epidemiology of Endometrial Cancer Consortium (E2C2). Crous-Bou, Marta, Mengmeng Du, Marc J. Gunter, Veronica W. Setiawan, Leo J. Schouten, Xiao-Ou Shu, Nicolas Wentzensen, Kimberly A. Bertrand, Linda S. Cook, Christine M. Friedenreich, Susan M. Gapstur, Marc T. Goodman, Torukiri I. Ibiebele, Carlo La Vecchia, Fabio Levi, Linda M. Liao, Eva Negri, Susan E. McCann, Kelly O’Connell, Julie R. Palmer, Alpa V. Patel, Jeanette Ponte, Peggy Reynolds, Carlotta Sacerdote, Rashmi Sinha, Amanda B. Spurdle, Britton Trabert, Piet A. van den Brandt, Penelope M. Webb, Stacey Petruzella, Sara H. Olson, Immaculata De Vivo, and Epidemiology of Endometrial Cancer Consortium (E2C2). The American Journal of Clinical Nutrition, August, nqac229.

Nature Versus Nurture Contribution to Prostate Cancer Risk. Freedland, Stephen J., and Nadine Adriana Friedrich. Nature Reviews. Urology, August.

Cardiac Surgery 

Editor’s Choice: The Most Cited Journal in Our Specialty. Chikwe, Joanna. The Annals of Thoracic Surgery 114 (3): 613–17.

Cardiology

Mitral Annular Disjunction: A Case Series and Review of the Literature. Wu, Stephanie, and Robert J. Siegel. Frontiers in Cardiovascular Medicine 9: 976066.

Sex Differences in Acute Coronary Syndromes: A Global Perspective. Cader, F. Aaysha, Shrilla Banerjee, and Martha Gulati. Journal of Cardiovascular Development and Disease 9 (8): 239.

Attitudes & Practices Surrounding Pregnancy Post Heart Transplant Among Pediatric Providers. Collins, Megan M., Zhining Ou, Morgan M. Millar, Michelle M. Kittleson, Lindsay J. May, Michelle S. Ploutz, Kimberly M. Molina, Katherine G. Hayes, and Ashwin K. Lal. The Journal of Heart and Lung Transplantation, July, S1053-2498(22)02062-9.

A Practical Approach to Invasive Testing in Ischemia With No Obstructive Coronary Arteries (INOCA). Bastiany, Alexandra, Christine Pacheco, Tara Sedlak, Jaqueline Saw, Steven E. S. Miner, Shuangbo Liu, Andrea Lavoie, Daniel H. Kim, Martha Gulati, and Michelle M. Graham. CJC Open 4 (8): 709–20.

Nationwide Study of Sex Differences in Incident Heart Failure in Newly Diagnosed Nonvalvular Atrial Fibrillation. Yogasundaram, Haran, Sunjidatul Islam, Douglas C. Dover, Nathaniel M. Hawkins, Justin Ezekowitz, Padma Kaul, and Roopinder K. Sandhu. CJC Open 4 (8): 701–8.

The State of Heart Failure Care in Canada: Minimal Improvement in Readmissions Over Time Despite an Increased Number of Evidence-Based Therapies. Poon, Stephanie, Benjamin Leis, Laurie Lambert, Kendra MacFarlane, Kim Anderson, Claudia Blais, Catherine Demers, Justin A. Ezekowitz, Nathaniel M. Hawkins, Douglas S. Lee, Gordon Moe, Roopinder K. Sandhu, Sean A. Virani, Stephen Wilton, Shelley Zieroth, and Robert McKelvie. CJC Open 4 (8): 667–75.

Coronary Artery Disease and Revascularization Associated With Immune Checkpoint Blocker Myocarditis: Report From an International Registry. Nowatzke, Joseph, Paul Guedeney, Nicholas Palaskas, Lorenz Lehmann, Stephane Ederhy, Han Zhu, Jennifer Cautela, Sanjeev Francis, Pierre-Yves Courand, Anita Deswal, Steven M. Ewer, Mandar Aras, Dimitri Arangalage, Kambiz Ghafourian, Charlotte Fenioux, Daniel Finke, Giovanni Peretto, Vlad Zaha, Osnat Itzhaki Ben Zadok, Kazuko Tajiri, Nausheen Akhter, Joshua Levenson, Lauren Baldassarre, John Power, Shi Huang, Jean-Philippe Collet, Javid Moslehi, Joe-Elie Salem, and International ICI-myocarditis registry contributors. European Journal of Cancer (Oxford, England: 1990), August, S0959-8049(22)00443-9.

Harnessing Passion and Real-World Data to Transform Post-Market Surveillance of Cardiac Implanted Electronic Leads. Piccini, Jonathan P., Andrea M. Russo, and Charles Swerdlow. Journal of Interventional Cardiac Electrophysiology: An International Journal of Arrhythmias and Pacing, August.

C. Richard Conti and Chinese Cardiology 1989-2022. Harold, John Gordon. Clinical Cardiology, August.

Polygenic Risk Score Predicts Sudden Death in Patients With Coronary Disease and Preserved Systolic Function. Sandhu, Roopinder K., Jacqueline S. Dron, Yunxian Liu, M. Vinayaga Moorthy, Neal A. Chatterjee, Patrick T. Ellinor, Daniel I. Chasman, Nancy R. Cook, Amit V. Khera, and Christine M. Albert. Journal of the American College of Cardiology 80 (9): 873–83.

Two-Year Clinical Outcomes after Successful Transcatheter Aortic Valve Implantation With Balloon-Expandable Versus Self-Expanding Valves: A Subanalysis of the GALILEO Trial. Okuno, Taishi, George D. Dangas, Christian Hengstenberg, Samantha Sartori, Howard C. Herrmann, Robert de Winter, Martine Gilard, Didier Tchétché, Helge Möllmann, Raj R. Makkar, Stephan Baldus, Ole De Backer, Bjørn Bendz, Annapoorna Kini, Dirk von Lewinski, Michael Mack, Raúl Moreno, Ulrich Schäfer, Jochen Wöhrle, Julia Seeger, Clayton Snyder, Johny Nicolas, Jan G. P. Tijssen, Robert C. Welsh, Pascal Vranckx, Marco Valgimigli, Roxana Mehran, Samir Kapadia, Lars Sondergaard, and Stephan Windecker. Catheterization and Cardiovascular Interventions, August.

Sex Differences in Atrial Fibrillation Risk: The VITAL Rhythm Study. Siddiqi, Hasan K., Manickavasagar Vinayagamoorthy, Baris Gencer, Chee Ng, Julie Pester, Nancy R. Cook, I.-Min Lee, Julie Buring, JoAnn E. Manson, and Christine M. Albert. JAMA Cardiology, August.

TBK1 and GABARAP Family Members Suppress Coxsackievirus B Infection by Limiting Viral Production and Promoting Autophagic Degradation of Viral Extracellular Vesicles. Sawaged, Savannah, Thomas Mota, Honit Piplani, Reetu Thakur, Deepti Lall, Elizabeth McCabe, Soojung Seo, Fayyaz S. Sutterwala, Ralph Feuer, Roberta A. Gottlieb, and Jon Sin. PLoS Pathogens 18 (8): e1010350. 

Parallelization With Dual-Trap Single-Column Configuration Maximizes Throughput of Proteomic Analysis. Kreimer, Simion, Ali Haghani, Aleksandra Binek, Alisse Hauspurg, Saeed Seyedmohammad, Alejandro Rivas, Amanda Momenzadeh, Jesse G. Meyer, Koen Raedschelders, and Jennifer E. Van Eyk. Analytical Chemistry, August.

Computational Biomedicine 

SurvMaximin: Robust Federated Approach to Transporting Survival Risk Prediction Models. Wang, Xuan, Harrison G. Zhang, Xin Xiong, Chuan Hong, Griffin M. Weber, Gabriel A. Brat, Clara-Lea Bonzel, Yuan Luo, Rui Duan, Nathan P. Palmer, Meghan R. Hutch, Alba Gutiérrez-Sacristán, Jason H. Moore, Consortium for Clinical Characterization of COVID-19 by EHR 4CE, et al. Journal of Biomedical Informatics, August, 104176.

Imaging

Framed and Reframed! The Art of Using Cognitive Behavioral Techniques to Combat Burnout. Catanzano, Tara, Shahrzad Azizaddini, M. Jane Clayton, Theresa Pham, Sosamma T. Methratta, Michael D. C. Fishman, Franklin G. Moser, and N. Reed Dunnick. Current Problems in Diagnostic Radiology, July, S0363-0188(22)00109-8.

Medicine

Diversity, Equity, and Inclusion in Gastroenterology and Hepatology: A Survey of Where We Stand. Rahal, Harman K., James H. Tabibian, Rachel B. Issaka, Sandra Quezada, Darrell M. Gray, Sophie Balzora, Liu Yang, Jayraan Badiee, and Folasade P. May. The American Journal of Gastroenterology, August.

Through-the-Scope Suturing Is Feasible and Safe to Perform With Duodenoscopes. Ghaith, Jenan, Kenneth H. Park, and Simon K. Lo. Gastrointestinal Endoscopy, August, S0016-5107(22)01935-6.

Potential Mechanisms for Lung Fibrosis Associated With COVID-19 Infection. Parimon, Tanyalak, Milena Espindola, Alberto Marchevsky, Reinaldo Rampolla, Peter Chen, and Cory M. Hogaboam. QJM: Monthly Journal of the Association of Physicians, August, hcac206.

Chondral Delamination of the Knee and Its Management: A Case Report and Review Article. Mansour, Marah, Yazan Abboud, Mhd Alaa Aldin Alhaffar, Ola Souliman, Massa Haffar, Younes Mustafa, Tamim Alsuliman, and Michel Samaan. BMC Surgery 22 (1): 325.

Large-Scale Sequencing Identifies Multiple Genes and Rare Variants Associated With Crohn’s Disease Susceptibility. Sazonovs, Aleksejs, Christine R. Stevens, Guhan R. Venkataraman, Kai Yuan, Brandon Avila, Maria T. Abreu, Tariq Ahmad, Matthieu Allez, Ashwin N. Ananthakrishnan, Gil Atzmon, Aris Baras, Jeffrey C. Barrett, Mark J. Daly, et al. Nature Genetics, August.

Quantitative MRI of Chronic Pancreatitis: Results From a Multi-Institutional Prospective Study, Magnetic Resonance Imaging as a Non-Invasive Method for Assessment of Pancreatic Fibrosis (MINIMAP). Tirkes, Temel, Dhiraj Yadav, Darwin L. Conwell, Paul R. Territo, Xuandong Zhao, Scott A. Persohn, Anil K. Dasyam, Zarine K. Shah, Sudhakar K. Venkatesh, Naoki Takahashi, Ashley Wachsman, Liang Li, Yan Li, Stephen J. Pandol, Walter G. Park, Santhi S. Vege, Phil A. Hart, Mark Topazian, Dana K. Andersen, Evan L. Fogel, and Consortium for the Study of Chronic Pancreatitis, Diabetes, Pancreatic Cancer (CPDPC). Abdominal Radiology (New York), August.

Cryobanking of Human Distal Lung Epithelial Cells for Preservation of Their Phenotypic and Functional Characteristics. Konda, Bindu, Apoorva Mulay, Changfu Yao, Edo Israely, Stephen Beil, Carissa A. Huynh, Warren G. Tourtellotte, Reinaldo Rampolla, Peter Chen, Gianni Carraro, and Barry R. Stripp. American Journal of Respiratory Cell and Molecular Biology, August.

Neurology

Acute Kidney Injury-Associated Delirium: A Review of Clinical and Pathophysiological Mechanisms. Pang, Haoming, Sanjeev Kumar, E. Wesley Ely, Michael M. Gezalian, and Shouri Lahiri. Critical Care (London, England) 26 (1): 258.

Nursing

Dyslipidemia in Midlife Women: Approach and Considerations During the Menopausal Transition. Torosyan, Nare, Parth Visrodia, Tina Torbati, Margo B. Minissian, and Chrisandra L. Shufelt. Maturitas 166 (August): 14–20.

Clinical Application of Risk Assessment in PAH: Expert Center APRN Recommendations. Wilson, Melisa, Jennifer Keeley, Martha Kingman, Susanne McDevitt, Jacqueline Brewer, Frances Rogers, Wendy Hill, Zachary Rideman, and Meredith Broderick. Pulmonary Circulation 12 (3): e12106.

Characterizing the Relationship Between Coronavirus Disease 2019 (COVID-19) and Central-Line-Associated Bloodstream Infection (CLABSI) and Assessing the Impact of a Nursing-Focused CLABSI Reduction Intervention During the COVID-19 Pandemic. Ben-Aderet, Michael A., Meghan S. Madhusudhan, Pishoy Haroun, Matthew J. P. Almario, Ryan Raypon, Sharon Fawcett, Julie Johnson, Anita Girard, Todd Griner, Lorraine Sheffield, and Jonathan D. Grein. Infection Control and Hospital Epidemiology, August, 1–8.

OBGYN

Race/Ethnicity Differences in Response to Acute Antihypertensive Treatment of Peripartum Severe Hypertension. Greene, Naomi H., Fay F. Pon, and Sarah J. Kilpatrick. The Journal of Maternal-Fetal & Neonatal Medicine, August, 1–7.

Orthopaedics

Suture Tape Augmentation Increases the Time-Zero Stiffness and Strength of Anterior Cruciate Ligament Grafts: A Cadaveric Study. Torres, Stephen J., Trevor J. Nelson, Nathalie Pham, William Uffmann, Orr Limpisvasti, and Melodie F. Metzger. Arthroscopy, Sports Medicine, and Rehabilitation 4 (4): e1253–59.

Pediatrics

Technological Imbalance: Seeking a Small-Caliber Duodenoscope. Lin, Tom K., Bradley Barth, Douglas S. Fishman, Victor L. Fox, Matthew J. Giefer, Roberto Gugig, Robert E. Kramer, Quin Y. Liu, Petar Mamula, Mark E. McOmber, David S. Vitale, Michael J. Wilsey, and David M. Troendle. Gastrointestinal Endoscopy, August, S0016-5107(22)01933-2.

Surgery

Tbx18 Orchestrates Cytostructural Transdifferentiation of Cardiomyocytes to Pacemaker Cells by Recruiting the Epithelial-Mesenchymal Transition Program. Foster, D. Brian, Jin-Mo Gu, Elizabeth H. Kim, David W. Wolfson, Robert O’Meally, Robert N. Cole, and Hee Cheol Cho. Journal of Proteome Research, August.

Tracheal Rupture After Tracheostomy Tube Exchange in a Patient With Recurrent Oral Cavity Spindle Cell Carcinoma. Raskin, Jonathan, Michela Borrelli, Tasha Nasrollahi, and Chase Heaton. Ear, Nose, & Throat Journal, August, 1455613221123854.

Rhinoplasty Complication Requiring Multiple Revisions. Raskin, Jonathan, Michela Borrelli, Tasha Nasrollahi, and Henry Chen. Ear, Nose, & Throat Journal, August, 1455613221123826.