Faculty Publications: Aug. 18-25

This week’s edition of Faculty Publications includes Cedars-Sinai studies that were published Aug. 18-25. If you have a published paper from this period that does not appear on this list, please contact Sue Marone, who will add it to next week’s collection.

Biomedical Sciences 

Early-Life Reflections of Grimod de La Reyniere, Founder of French Gastronomic Writing: Excerpts of Reflexions Philosophique Sur Le Plaisir (1783) and Lorgnette Philosophique (1785). Fine, Leon G. International Journal of Gastronomy and Food Science 29 (September): 100580.

Cancer

Methylated Septin9 (MSEPT9): A Promising Blood-Based Biomarker for the Detection and Screening of Early-Onset Colorectal Cancer. Loomans-Kropp, Holli A., Yurong Song, Manish Gala, Aparna R. Parikh, Emily E. Van Seventer, Rocio Alvarez, Megan P. Hitchins, Robert H. Shoemaker, and Asad Umar. Cancer Research Communications 2 (2): 90–98.

Phenotypic Plasticity - Alternate Transcriptional Programs Driving Treatment Resistant Prostate Cancer. Nanda, Jagpreet Singh, Praveen Koganti, Graziela Perri, and Leigh Ellis. Critical Reviews in Oncogenesis 27 (1): 45–60.

The Deleterious Effects of Smoking on the Development and Progression of Chronic Pancreatitis. Han, Samuel Y., Darwin L. Conwell, Philip T. Diaz, Amy Ferketich, Christie Y. Jeon, Dhiraj Yadav, and Phil A. Hart. Pancreatology, August, S1424-3903(22)00474-4.

Are Higher Pre-Diagnosis Follicle Stimulating Hormone Levels Associated With Long-Term Prostate Cancer Risk? Dymanus, Kyle, Lauren E. Howard, Taofik Oyekunle, Amanda M. De Hoedt, Artak Labadzhyan, Thomas Polascik, Stephen J. Freedland, and Zachary Klaassen. The Prostate, August.

Neuropilin-2 Promotes Lineage Plasticity and Progression to Neuroendocrine Prostate Cancer. Wang, Jing, Jingjing Li, Lijuan Yin, Tianjie Pu, Jing Wei, Varsha Karthikeyan, Tzu-Ping Lin, Allen C. Gao, and Boyang Jason Wu. Oncogene, August.

A Validation of Models for Prediction of Pathogenic Variants in Mismatch Repair Genes. Shyr, Cathy, Amanda L. Blackford, Theodore Huang, Jianfeng Ke, Nofal Ouardaoui, Lorenzo Trippa, Sapna Syngal, Chinedu Ukaegbu, Hajime Uno, Khedoudja Nafa, Zsofia K. Stadler, Kenneth Offit, Christopher I. Amos, Patrick M. Lynch, Sining Chen, Francis M. Giardiello, Daniel D. Buchanan, John L. Hopper, Mark A. Jenkins, Melissa C. Southey, Aung Ko Win, Jane C. Figueiredo, Danielle Braun, and Giovanni Parmigiani. Genetics in Medicine, August, S1098-3600(22)00841-3.

Disparities in Curative Treatments and Outcomes for Early Stage Intrahepatic Cholangiocarcinoma in the United States. Lee, Yi-Te, Amit G. Singal, Marie Lauzon, Vatche G. Agopian, Michael Luu, Mazen Noureddin, Tsuyoshi Todo, Irene K. Kim, Marc L. Friedman, Kambiz Kosari, Nicholas N. Nissen, Lewis R. Roberts, Julie K. Heimbach, Gregory J. Gores, and Ju Dong Yang. Cancer, August.

Cardiac Surgery 

Characteristics, Outcomes, and Predictors of de Novo Malignancy After Heart Transplantation. Youn, Jong-Chan, Darae Kim, In-Cheol Kim, Hye Sun Lee, Jin-Oh Choi, Eun-Seok Jeon, Keith Nishihara, Evan P. Kransdorf, David H. Chang, Michelle M. Kittleson, Jignesh K. Patel, Danny Ramzy, Fardad Esmailian, and Jon A. Kobashigawa. Frontiers in Cardiovascular Medicine 9: 939275.

Does a Boot Camp Expand Skills Rapidly? McKee Wiggins, Luke, M. Mujeeb Zubair, Dominic Emerson, and Richard W. Kim. JTCVS Open 10 (June): 293–95.

Cardiology

Association of Birth Year of Pregnant Individuals With Trends in Hypertensive Disorders of Pregnancy in the United States, 1995-2019. Cameron, Natalie A., Lucia C. Petito, Nilay S. Shah, Amanda M. Perak, Janet M. Catov, Natalie A. Bello, Simon Capewell, Martin O’Flaherty, Donald M. Lloyd-Jones, Philip Greenland, William A. Grobman, and Sadiya S. Khan. JAMA Network Open 5 (8): e2228093.

Alterations in the Kallikrein-Kinin System Predict Death After Heart Transplant. Giangreco, Nicholas P., Guillaume Lebreton, Susan Restaino, Maryjane Farr, Emmanuel Zorn, Paolo C. Colombo, Jignesh Patel, Rajesh Kumar Soni, Pascal Leprince, Jon Kobashigawa, Nicholas P. Tatonetti, and Barry M. Fine. Scientific Reports 12 (1): 14167.

Sympathetic Toggled Sinus Rate Acceleration as a Mechanism of Sustained Sinus Tachycardia in Chronic Orthostatic Intolerance Syndrome. Hwang, Daerin, Xiao Liu, Carine Rosenberg, Andrew Lee, Sanjana Borle, Joselyn Q. Ricafrente, Janet Wei, Chrisandra Shufelt, Lan S. Chen, Xiaochun Li, Joshua I. Goldhaber, C. Noel Bairey Merz, and Peng-Sheng Chen. Heart Rhythm, August, S1547-5271(22)02311-6.

Self-Expanding Transcatheter vs Surgical Aortic Valve Replacement in Intermediate-Risk Patients: 5-Year Outcomes of the SURTAVI Randomized Clinical Trial. Van Mieghem, Nicolas M., G. Michael Deeb, Lars Søndergaard, Eberhard Grube, Stephan Windecker, Hemal Gada, Mubashir Mumtaz, Peter S. Olsen, John C. Heiser, William Merhi, Neal S. Kleiman, Stanley J. Chetcuti, Thomas G. Gleason, Joon Sup Lee, Wen Cheng, Raj R. Makkar, Juan Crestanello, Barry George, Isaac George, Susheel Kodali, Steven J. Yakubov, Patrick W. Serruys, Rüdiger Lange, Nicolo Piazza, Mathew R. Williams, Jae K. Oh, David H. Adams, Shuzhen Li, Michael J. Reardon, and SURTAVI Trial Investigators. JAMA Cardiology, August.

Computational Biomedicine 

Predictive Value of Common Genetic Variants in Idiopathic Pulmonary Fibrosis Survival. Mota, Patrícia Caetano, Miguel Luz Soares, Carlos Daniel Vasconcelos, António Carlos Ferreira, Bruno A. Lima, Elisabetta Manduchi, Jason H. Moore, Natália Melo, Hélder Novais-Bastos, José Miguel Pereira, Susana Guimarães, Conceição Souto Moura, José Agostinho Marques, and António Morais. Journal of Molecular Medicine (Berlin, Germany) 100 (9): 1341–53.

Imaging

Pericoronary Adipose Tissue Attenuation, Low-Attenuation Plaque Burden, and 5-Year Risk of Myocardial Infarction. Tzolos, Evangelos, Michelle C. Williams, Priscilla McElhinney, Andrew Lin, Kajetan Grodecki, Guadalupe Flores Tomasino, Sebastien Cadet, Jacek Kwiecinski, Mhairi Doris, Philip D. Adamson, Alastair J. Moss, Shirjel Alam, Amanda Hunter, Anoop S. V. Shah, Nicholas L. Mills, Tania Pawade, Chengjia Wang, Jonathan R. Weir-McCall, Giles Roditi, Edwin J. R. van Beek, Leslee J. Shaw, Edward D. Nicol, Daniel S. Berman, Piotr J. Slomka, Marc R. Dweck, David E. Newby, and Damini Dey. JACC. Cardiovascular Imaging15 (6): 1078–88.

Long-Term Survival Benefit From Revascularization Compared With Medical Therapy in Patients With or Without Diabetes Undergoing Myocardial Perfusion Single Photon Emission Computed Tomography. Kuronuma, Keiichiro, Donghee Han, Robert J. H. Miller, Alan Rozanski, Heidi Gransar, Damini Dey, Sean W. Hayes, John D. Friedman, Louise Thomson, Piotr J. Slomka, and Daniel S. Berman. Diabetes Care, August, dc220454.

Decreased Hospital Length of Stay for ICH and PE After Adoption of an Artificial Intelligence-Augmented Radiological Worklist Triage System. Petry, Michael, Charlotte Lansky, Yosef Chodakiewitz, Marcel Maya, and Barry Pressman. Radiology Research and Practice 2022 (August): e2141839.

Early-Stage COVID-19 Pandemic Observations on Pulmonary Embolism Using Nationwide Multi-Institutional Data Harvesting. Wismüller, Axel, Adora M. DSouza, Anas Z. Abidin, M. Ali Vosoughi, Christopher Gange, Isabel O. Cortopassi, Gracijela Bozovic, Alexander A. Bankier, Kiran Batra, Yosef Chodakiewitz, Yin Xi, Christopher T. Whitlow, Janardhana Ponnatapura, Gary J. Wendt, Eric P. Weinberg, Larry Stockmaster, David A. Shrier, Min Chul Shin, Roshan Modi, Hao Steven Lo, Seth Kligerman, Aws Hamid, Lewis D. Hahn, Glenn M. Garcia, Jonathan H. Chung, Talissa Altes, Suhny Abbara, and Anna S. Bader. NPJ Digital Medicine 5 (1): 120.

Medicine

HER2 Drives Lung Fibrosis by Activating a Metastatic Cancer Signature in Invasive Lung Fibroblasts.Liu, Xue, Yan Geng, Jiurong Liang, Ana Lucia Coelho, Changfu Yao, Nan Deng, Yizhou Wang, Kristy Dai, Guanling Huang, Ting Xie, Ningshan Liu, Simon C. Rowan, Forough Taghavifar, Vrishika Kulur, Zhenqiu Liu, Barry R. Stripp, Cory M. Hogaboam, Dianhua Jiang, and Paul W. Noble. The Journal of Experimental Medicine219 (10): e20220126.

Hypertension Is Prevalent in Non-Alcoholic Fatty Liver Disease and Increases All-Cause and Cardiovascular Mortality. Ng, Cheng Han, Zhen Yu Wong, Nicholas W. S. Chew, Kai En Chan, Jieling Xiao, Nilofer Sayed, Wen Hui Lim, Darren Jun Hao Tan, Ryan Wai Keong Loke, Phoebe Wen Lin Tay, Jie Ning Yong, Gywneth Kong, Daniel Q. Huang, Jiong-Wei Wang, Mark Chan, Mayank Dalakoti, Nobuharu Tamaki, Mazen Noureddin, Mohammad Shadab Siddiqui, Arun J. Sanyal, and Mark Muthiah. Frontiers in Cardiovascular Medicine 9: 942753.

Severe Nonspecific Interstitial Pneumonia (NSIP) in an Adolescent. Cerro Chiang, Giuliana, Christopher Lee, Alberto Marchevsky, and Michael I. Lewis. Case Reports in Pulmonology 2022: 7757776.

Impact of the COVID-19 Pandemic on Liver Disease-Related Mortality Rates in the United States. Gao, Xu, Fan Lv, Xinyuan He, Yunyu Zhao, Yi Liu, Jian Zu, Linda Henry, Jinhai Wang, Yee Hui Yeo, Fanpu Ji, and Mindie H. Nguyen. Journal of Hepatology, August, S0168-8278(22)02994-4.

Satisfaction With Telehealth Among Patients With Irritable Bowel Syndrome During COVID-19: Cross-Sectional Survey Findings. Yu, Christine, Stephanie Tovar, Jiaxiao Shi, Ariadna Padilla, Dana Pounds, Welmoed K. van Deen, Christopher V. Almario, and Bechien U. Wu. Clinical and Translational Gastroenterology, August.

Nontargeted and Targeted Metabolomic Profiling Reveals Novel Metabolite Biomarkers of Incident Diabetes in African Americans. Chen, Zsu-Zsu, Julian Avila Pacheco, Yan Gao, Shuliang Deng, Bennet Peterson, Xu Shi, Shuning Zheng, Usman A. Tahir, Daniel H. Katz, Daniel E. Cruz, Debby Ngo, Mark D. Benson, Jeremy M. Robbins, Xiuqing Guo, Magdalena Del Rocio Sevilla Gonzalez, Alisa Manning, Adolfo Correa, James B. Meigs, Kent D. Taylor, Stephen S. Rich, Mark O. Goodarzi, Jerome I. Rotter, James G. Wilson, Clary B. Clish, and Robert E. Gerszten. Diabetes, August, db220033.

Postvaccination Symptoms After a Third Dose of MRNA SARS-CoV-2 Vaccination in Patients With Inflammatory Bowel Disease: Results From CORALE-IBD. Li, Dalin, Philip Debbas, Angela Mujukian, Susan Cheng, Jonathan Braun, Dermot P. B. McGovern, Gil Y. Melmed, and CORALE-IBD Study Group. Inflammatory Bowel Diseases, August, izac174.

Eliciting Patients’ Healthcare Goals and Concerns: Do Questions Influence Responses? Scalia, Peter, Welmoed K. van Deen, Jaclyn A. Engel, Gabrielle Stevens, Aricca D. Van Citters, Megan M. Holthoff, Lisa C. Johnson, Alice M. Kennedy, Swathi B. Reddy, Eugene C. Nelson, and Glyn Elwyn. Chronic Illness 18 (3): 708–16.

Treatment Persistence and Adherence in People With Type 2 Diabetes Switching to IGlarLixi vs Free-Dose Combinations of Basal Insulin and Glucagon-like Peptide 1 Receptor Agonist. Edelman, Steven, Doreen Cassarino, David Kayne, Terry Dex, Xuan Li, and Francisco J. Pasquel. Journal of Managed Care & Specialty Pharmacy 28 (9): 958–68.

Neurology

CRISPR/Cas9 Screen in Human IPSC-Derived Cortical Neurons Identifies NEK6 as a Novel Disease Modifier of C9orf72 Poly(PR) Toxicity. Guo, Wenting, Haibo Wang, Arun Kumar Tharkeshwar, Julien Couthouis, Elke Braems, Pegah Masrori, Evelien Van Schoor, Yannan Fan, Karan Ahuja, Matthieu Moisse, Maarten Jacquemyn, Rodrigo Furtado Madeiro da Costa, Madhavsai Gajjar, Sriram Balusu, Tine Tricot, Laura Fumagalli, Nicole Hersmus, Rekin’s Janky, Francis Impens, Pieter Vanden Berghe, Ritchie Ho, Dietmar Rudolf Thal, Rik Vandenberghe, Muralidhar L. Hegde, Siddharthan Chandran, Bart De Strooper, Dirk Daelemans, Philip Van Damme, Ludo Van Den Bosch, and Catherine Verfaillie. Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association, August.

Treatment of Chronic Inflammatory Demyelinating Polyneuropathy. Allen, Jeffrey A., and Richard A. Lewis. Muscle & Nerve, August.

COVID-19 Exposures, Vaccines, and Acute Ischemic Stroke Risk: On Balance and In Balance. Simpkins, Alexis N., and Susan Cheng. Neurology, August, 10.1212/WNL.0000000000201109.

Orthopaedics

The Impact of COVID-19 Restrictions on Participant Enrollment in the PREPARE Trial. Pogorzelski, David, Paula McKay, Michael J. Weaver, Todd Jaeblon, Robert A. Hymes, Greg E. Gaski, Joanne Fraifogl, James S. Ahn, Sofia Bzovsky, Gerard Slobogean, Sheila Sprague, PREP-IT Investigators, Executive Committee, Gerard P. Slobogean, Sheila Sprague, Jeffrey Wells, Mohit Bhandari, Steering Committee, Adjudication Committee:, Data and Safety Monitoring Committee:, Research Methodology Core:, Patient Centred Outcomes Core:, Orthopaedic Surgery Core:, Operating Room Core:, Infectious Disease Core:, Military Core:, PREP-IT Clinical Sites, Lead Clinical SiteAqueous-PREP and PREPARE:, Robert V. O’Toole, Jean-Claude D’Alleyrand, Andrew Eglseder, Aaron Johnson, Christopher Langhammer, Christopher Lebrun, Jason Nascone, Raymond Pensy, Andrew Pollak, Marcus Sciadini, Gerard P. Slobogean, Yasmin Degani, Haley K. Demyanovich, Andrea Howe, Nathan N. O’Hara, Heather Phipps, Eric Hempen, Aqueous-PREP and PREPARE:, Aqueous-PREP:, and PREPARE: Contemporary Clinical Trials Communications, August, 100973.

Management of Severe Adult Spinal Deformity With Circumferential Minimally Invasive Surgical Strategies Without Posterior Column Osteotomies: A 13-Year Experience. Anand, Neel, Alisa Alayan, Christopher Kong, Sheila Kahwaty, Babak Khandehroo, David Gendelberg, and Andrew Chung. Spine Deformity 10 (5): 1157–68.

Pathology

Overexpressed Angiotensin Converting Enzyme in Neutrophils Suppresses Glomerular Damage in Crescentic Glomerulonephritis. Saito, Suguru, Narihito Tatsumoto, Duo-Yao Cao, Nobuyuki Nosaka, Hiroshi Nishi, Daniel N. Leal, Ellen A. Bernstein, Kenichi Shimada, Moshe Arditi, Kenneth E. Bernstein, and Michifumi Yamashita. American Journal of Physiology. Renal Physiology, August.

Solitary Fibrous Tumor of the Adrenal Gland. Jha, Shilpy, Sambit K. Mohanty, Nakul Y. Sampat, Subhasini Naik, Manas R. Baisakh, Niharika Pattnaik, Anandi Lobo, Sudhasmita Rauta, Shivani Sharma, Gauri Munjal, Deepika Jain, Samriti Arora, Vipra Malik, Ekta Jain, Biswajit Sahoo, Mohit Bhardwaj, Saurav K. Mishra, Sunil Jaiswal, Lalit M. Barik, Bonnie L. Balzer, Indranil Chakrabarti, and Anil V. Parwani. American Journal of Clinical Pathology, August, aqac088.

Surgery

YouTube as a Source for Information on Newborn Male Circumcision: Is YouTube a Reliable Patient Resource? Zaliznyak, Michael, John M. Masterson, and Barry Duel. Journal of Pediatric Urology, July, S1477-5131(22)00315-1.

Autologous Fat Grafting in the Upper Extremity: Defining New Indications. Deptula, Peter, Tennyson Block, Kylie Tanabe, and David Kulber. Plastic and Reconstructive Surgery. Global Open 10 (8): e4469.

A Better Way: Training for Direct Observations in Healthcare. Alfred, Myrtede, John Del Gaizo, Falisha Kanji, Samuel Lawton, Ashley Caron, Lynne S. Nemeth, A. V. Alekseyenko, Daniel Shouhed, Stephen Savage, Jennifer T. Anger, Ken Catchpole, and Tara Cohen. BMJ Quality & Safety, August, bmjqs-2021-014171.

Blunt Thoracic Aortic Injury: A Western Trauma Association Critical Decisions Algorithm. Brown, Carlos V. R., Marc de Moya, Karen J. Brasel, Jennifer L. Hartwell, Kenji Inaba, Eric J. Ley, Ernest E. Moore, Kimberly A. Peck, Anne G. Rizzo, Nelson G. Rosen, Jason L. Sperry, Jordan A. Weinberg, Alexis M. Moren, Joseph J. DuBose, Raul S. Coimbra, and Matthew J. Martin. The Journal of Trauma and Acute Care Surgery, August.

Food Sensitivities in a Diverse Nationwide Cohort of Veterans With Interstitial Cystitis/Bladder Pain Syndrome. Jarman, Aubrey, Jessica L. Janes, Barbara Shorter, Robert Moldwin, Amanda M. De Hoedt, Kamil E. Barbour, Jayoung Kim, Stephen J. Freedland, and Jennifer T. Anger. The Journal of Urology, August, 101097JU0000000000002938.