Current Research
The primary vision of the Center for Bioinformatics and Functional Genomics (CBFG) is to establish a research nexus that integrates leading-edge developments in computational sciences, next-generation genomics and epigenomics and functional biology to improve our understanding of disease etiology applied to personalized medicine. We utilize next-generation sequencing technologies, evolving computational methodologies, and functional assays to understand the underlying biological mechanisms driving cancer and other diseases, and apply these in the clinical setting to advance personalized health.
Bioinformatics
Genomics
Functional Genomics
Emphasis on Collaborative Approach
- Cross-departmental working groups established within the CBFG:
- GWAS functional follow-up team
- Computational pipeline team
- Genetic epidemiology team
- Genomic-epigenomic tumor profiling team
- Single cell team
- Functional screening team
- IP-seq team
- Collaborative environment utilizing expertise to train collaborator laboratory staff on technologies and use of leading-edge technologies.
Driven by Technology Adoption and Development
- Separated pre- and post-PCR laboratories
- Virus production and downstream cell culture facilities
- NGS library QC suite
- Bioinformatics suite
- Genome-wide CRISPR and shRNA screening libraries
- Illumina miniseq
- Agilent bioanalyzer
- Olympic florescent microscope
- 10x genomics single cell controller
- MERFISH
Education, Training and Outreach
- Weekly Omics seminar
- Monthly technology workshops
- Single cell RNAseq
- ChIP sequencing/epigenomic profiling
- Whole genome sequencing
- Whole genome bisulfite sequencing
- Proteomics
- Genome editing
- PhD student rotations
- Interdisciplinary mentorship of trainees
Have Questions or Need Help?
Contact us if you have questions, or wish to learn more about bioinformatics and functional genomics research at Cedars-Sinai.
Spielberg
8723 Alden Drive, Suite 100
Los Angeles, CA 90048