Los Angeles,
10
June
2022
|
13:00 PM
America/Los_Angeles

Faculty Publications: June 1-9

A Comprehensive Digest of Research Publications From Cedars-Sinai Investigators

This week’s edition of Faculty Publications includes Cedars-Sinai studies that were published between June 1-9. If you have a published paper from this period that does not appear on this list, please contact Sue Marone, who will add it to next week’s collection.

Anesthesiology 

Addressing Comorbidities in the Perioperative Setting and Optimizing Perioperative Medicine Education. Krishnan, Sindhu, Janet O. Adeola, and Richard D. Urman. Current Opinion in Anesthesiology 35 (3): 376–79.

It’s Not Just the Prices: Time-Driven Activity-Based Costing for Initiation of Veno-Venous Extracorporeal Membrane Oxygenation at Three International Sites-A Case Review. Nurok, Michael, Vin Pellegrino, Marc Pineton de Chambrun, Jonathan Warsh, Meredith Young, Erik Dong, Neil Parrish, Syed Shehab, Alain Combes, and Robert S. Kaplan. Anesthesia and Analgesia, June.

Cancer 

A Lung Cancer Screening Education Program Impacts Both Referral Rates and Provider and Medical Assistant Knowledge at Two Federally Qualified Health Centers. Akhtar, Aamna, Ernesto Sosa, Samuel Castro, Melissa Sur, Vanessa Lozano, Gail D’Souza, Sophia Yeung, et al. Clinical Lung Cancer 23 (4): 356–63.

Cost-Effectiveness of Hyperthermic Intraperitoneal Chemotherapy at Primary Cytoreduction of Epithelial Ovarian Cancer Based on Residual Disease Status. Penn, Courtney A., Erica V. Carballo, Christine S. Walsh, Oliver Zivanovic, and Kenneth H. Kim. Gynecologic Oncology Reports 41 (June): 101009.

Detecting the ‘Undetectable’ Alterations: Use of NGS to Uncover High-Risk Alterations. Halprin, Chelsea, Sumire Kitahara, Eric Vail, and Celeste C. Eno. Cancer Genetics 264–265 (June): 5–7.

Endoscopic Assessment of Radiological Stage IVA Cervical Cancer: A Bivariate Meta-Analysis Supporting an Evidence-Based Staging Algorithm Proposal. Sapienza, Lucas G., Justin J. Thomas, Timothy N. Showalter, Alfredo E. Echeverria, Michelle S. Ludwig, Albert C. Chen, Eunji Jo, et al. Gynecologic Oncology 165 (3): 642–49.

High Neutrophil-Lymphocyte Ratio and Delta Neutrophil-Lymphocyte Ratio Are Associated With Increased Mortality in Patients With Hepatocellular Cancer. Rich, Nicole E., Aarthi Parvathaneni, Ahana Sen, Mobolaji Odewole, Ana Arroyo, Arjmand R. Mufti, Thomas A. Kerr, et al. Digestive Diseases and Sciences 67 (6): 2666–76.

Variation in Molecularly Defined Prostate Tumor Subtypes by Self-Identified Race. Kensler, Kevin H., Shivanshu Awasthi, Mohamed Alshalalfa, Bruce J. Trock, Stephen J. Freedland, Michael R. Freeman, Sungyong You, et al. European Urology Open Science 40 (June): 19–26.

Emerging Drugs for the Treatment of Hepatocellular Carcinoma. Ayoub, Walid S., Patricia D. Jones, Ju Dong Yang, and Paul Martin. Expert Opinion on Emerging Drugs, June.

Extended Human Papillomavirus Genotyping to Predict Progression to High-Grade Cervical Precancer: A Prospective Cohort Study in the Southeastern United States. Bukowski, Alexandra, Cathrine Hoyo, Michael G. Hudgens, Wendy R. Brewster, Fidel Valea, Rex C. Bentley, Adriana C. Vidal, et al. Cancer Epidemiology, Biomarkers & Prevention June, cebp.0054.2022-1-15 10:41:07.593.

Extracorporeal Membrane Oxygenation as a Bridge to Durable Mechanical Circulatory Support or Heart Transplantation. Hansen, Breanna, Tahli Singer Englar, Robert Cole, Pedro Catarino, David Chang, Lawrence Czer, Dominic Emerson, et al. The International Journal of Artificial Organs, June, 3913988221103284.

Phase II Randomized Study of Ramucirumab and Pembrolizumab Versus Standard of Care in Advanced Non-Small-Cell Lung Cancer Previously Treated With Immunotherapy-Lung-MAP S1800A.Reckamp, Karen L., Mary W. Redman, Konstantin H. Dragnev, Katherine Minichiello, Liza C. Villaruz, Bryan Faller, Tareq Al Baghdadi, et al. Journal of Clinical Oncology June, JCO2200912.

Retrospective Analysis of Real-World Management of EGFR-Mutated Advanced NSCLC, After First-Line EGFR-TKI Treatment: US Treatment Patterns, Attrition, and Survival Data. Nieva, Jorge, Karen L. Reckamp, Danielle Potter, Aliki Taylor, and Ping Sun. Drugs - Real World Outcomes, June.

Identifying Colorectal Cancer Caused by Biallelic MUTYH Pathogenic Variants Using Tumor Mutational Signatures. Georgeson, Peter, Tabitha A. Harrison, Bernard J. Pope, Syed H. Zaidi, Conghui Qu, Robert S. Steinfelder, Yi Lin, et al. Nature Communications 13 (1): 3254.

Pre-Surgery Adhesion Molecules and Angiogenesis Biomarkers Are Differently Associated With Outcomes in Colon and Rectal Cancer: Results from the ColoCare Study. Ose, Jennifer, Biljana Gigic, Sheetal Hardikar, Tengda Lin, Caroline Himbert, Christy A. Warby, Anita R. Peoples, et al. Cancer Epidemiology, Biomarkers & Prevention June, cebp.EPI-22-0092-A.2022-1-26 16:00:24.177.

Validation of the Prostate Cancer Comorbidity Index in Predicting Cause-Specific Mortality in Men Undergoing Radical Prostatectomy. Chen, Michelle S., Lauren E. Howard, Shannon Stock, Anna Dolgner, Stephen J. Freedland, William Aronson, Martha Terris, et al. Prostate Cancer and Prostatic Diseases, June.

Single-Cell Spatial Analysis of Tumor Immune Architecture in Diffuse Large B-Cell Lymphoma. Colombo, Anthony, Monirath Hav, Mohan Singh, Alexander Xu, Alicia Gamboa, Tucker Lemos, Erik Gerdtsson, et al. Blood Advances, June, bloodadvances.2022007493.

The Associations of Multivitamin- and Antioxidant-Use With Mortality among Women and Men Diagnosed With Colorectal Cancer. Figueiredo, Jane C., Mark A. Guinter, Christina C. Newton, Marjorie L. McCullough, Caroline Y. Um, Alpa V. Patel, and Peter T. Campbell. JNCI Cancer Spectrum, June, pkac041.

Prostate Cancer Therapy Personalization via Multi-Modal Deep Learning on Randomized Phase III Clinical Trials.  Esteva, Andre, Jean Feng, Douwe van der Wal, Shih-Cheng Huang, Jeffry P. Simko, Sandy DeVries, Emmalyn Chen, et al. NPJ Digital Medicine 5 (1): 71.

Association of Sugar Intake with Inflammation- and Angiogenesis-Related Biomarkers in Newly Diagnosed Colorectal Cancer Patients. Stewart, Kelly L., Biljana Gigic, Caroline Himbert, Christy A. Warby, Jennifer Ose, Tengda Lin, Petra Schrotz-King, et al. Nutrition & Cancer 74 (5): 1636–43.

Cardiac Surgery 

Editor’s Choice: Strengths, Challenges, and Opportunities. Chikwe, Joanna. The Annals of Thoracic Surgery 113 (6): 1761–66.

Directed Hypercapnia for Weaning from ECMO to Mechanical Ventilation - Progress or Just a Process?Megna, Dominick, Asishana Osho, and Pedro Catarino. The Annals of Thoracic Surgery, June, S0003-4975(22)00795-0.

Cardiology 

Are We Any WISER yet? Progress and Contemporary Need for Smart Trials to Include Women in Coronary Artery Disease Trials. Iribarren, Ana, Márcio Augusto Diniz, C. Noel Bairey Merz, Chrisandra Shufelt, and Janet Wei. Contemporary Clinical Trials 117 (June): 106762.

Associations between Adherence to the Dietary Approaches to Stop Hypertension (DASH) Diet and Six Glucose Homeostasis Traits in the Microbiome and Insulin Longitudinal Evaluation Study (MILES). Ramesh, Gautam, Alexis C. Wood, Matthew A. Allison, Stephen S. Rich, Elizabeth T. Jensen, Yii-Der I. Chen, Jerome I. Rotter, Alain G. Bertoni, and Mark O. Goodarzi. Nutrition, Metabolism, and Cardiovascular Diseases: NMCD 32 (6): 1418–26.

Differences of Inflammatory Cytokine Profile in Patients With Vulnerable Plaque: A Coronary CTA Study. Roesner, Caroline, Markus Goeller, Dorette Raaz-Schrauder, Damini Dey, Tobias Kilian, Stephan Achenbach, Mohamed Marwan, and Daniel O. Bittner. Atherosclerosis 350 (June): 25–32.

Heart Rhythm Society Atrial Fibrillation Centers of Excellence Study: A Survey Analysis of Stakeholder Practices, Needs, and Barriers. Sandhu, Roopinder K., Amber Seiler, Colleen J. Johnson, T. Jared Bunch, Thomas F. Deering, Thomas Deneke, Paulus Kirchhof, et al. Heart Rhythm 19 (6): 1039–48.

Internal Medicine Resident Education Improves Cardiac Rehabilitation Knowledge, Attitudes, and Referral Rates: A Pilot Study. Wang, Maggie, Nare Torosyan, C. Noel Bairey-Merz, Janet Wei, and Chrisandra L. Shufelt. American Journal of Preventive Cardiology 10 (June): 100349.

Out-of-Hospital Cardiac Arrest With Onset Witnessed by Emergency Medical Services: Implications for Improvement in Overall Survival. Holmström, Lauri, Kyndaron Reinier, Lorrel Toft, Henry Halperin, Angelo Salvucci, Jonathan Jui, and Sumeet S. Chugh. Resuscitation 175 (June): 19–27.

Predominant Posterior Annular Dilatation Is Associated With Vena Contracta Morphology in Atrial Functional Tricuspid Regurgitation. Utsunomiya, Hiroto, Jun Yoshida, Kanako Izumi, Hajime Takemoto, Yusuke Ueda, Yukiko Nakano, and Takahiro Shiota. Journal of the American Society of Echocardiography 35 (6): 588–99.

Renal Artery Variations in Patients With Mild-to-Moderate Hypertension From the RADIANCE-HTN SOLO Trial. Sanghvi, Kintur, Yale Wang, Joost Daemen, Anthony Mathur, Ajay Jain, Suhail Dohad, Marc Sapoval, et al. Cardiovascular Revascularization Medicine: Including Molecular Interventions 39 (June): 58–65.

Sex Differences and Temporal Trends in Revascularization and Outcomes of ST-Elevation Myocardial Infarction in Older Adults in the United States. Ye, Guojie, Varun K. Pattisapu, Peiwen Wang, Lu Cheng, Siyang Yao, and Hua Hao. Archives of Medical Research 53 (4): 441–50.

Sudden Cardiac Arrest in Patients With Schizophrenia: A Population-Based Study of Resuscitation Outcomes and Pre-Existing Cardiovascular Disease. Edwards, Gabriel G., Audrey Uy-Evanado, Eric C. Stecker, Angelo Salvucci, Jonathan Jui, Sumeet S. Chugh, and Kyndaron Reinier. International Journal of Cardiology. Heart & Vasculature 40 (June): 101027.

Deep Learning Preoperative Risk Stratification. Ouyang, David, William Hiesinger, and Curt Langlotz. The Annals of Thoracic Surgery, June, S0003-4975(22)00796-2.

Long-Term Preservation of Functional Capacity and Quality of Life in Advanced Heart Failure Patients With Bridge to Transplant Therapy: A Report from Japanese Nationwide Multicenter Registry. Sato, Takuma, Yuta Kobayashi, Toshiyuki Nagai, Takeshi Nakatani, Jon Kobashigawa, Yoshikatsu Saiki, Minoru Ono, Satoru Wakasa, and Toshihisa Anzai. International Journal of Cardiology 356 (June): 66–72.

Sex Differences in Blood Pressure-A Measured Relook at Measures. Bello, Natalie A., and Susan Cheng. JAMA Network Open 5 (6): e2215521.

Hypoattenuated Leaflet Thickening (HALT) and Reduced Leaflet Motion (RELM) of Aortic Bioprostheses: An Imaging Finding or a Complication? Ahmad, Yousif, Raj Makkar, and Lars Sondergaard. Progress in Cardiovascular Diseases, June, S0033-0620(22)00058-5.

Biological Substrate Modification Suppresses Ventricular Arrhythmias in a Porcine Model of Chronic Ischaemic Cardiomyopathy. Dawkins, James F., Ashkan Ehdaie, Russell Rogers, Daniel Soetkamp, Jackelyn Valle, Kevin Holm, Lizbeth Sanchez, et al. European Heart Journal 43 (22): 2139–56.

Longitudinal Quantitative Assessment of Coronary Atherosclerosis Related to Normal Systolic Blood Pressure Maintenance in the Absence of Established Cardiovascular Disease. Won, Ki-Bum, Hyung-Bok Park, Ran Heo, Byoung Kwon Lee, Fay Y. Lin, Martin Hadamitzky, Yong-Jin Kim, et al. Clinical Cardiology, June.

Association between Aspirin Use During Pregnancy and Cardiovascular Risk Factors 2-7 Years after Delivery: The NuMoM2b Heart Health Study. Theilen, Lauren H., Philip Greenland, Jasmina Varagic, Janet Catov, Anthony Shanks, Vanessa Thorsten, Corette B. Parker, et al. Pregnancy Hypertension 28 (June): 28–34.

Sodium-Glucose Cotransporter 2 Inhibitors in Patients With Heart Failure: A Systematic Review and Meta-Analysis of Randomized Trials. Ahmad, Yousif, Mahesh V. Madhavan, Gregg W. Stone, Darrel P. Francis, Raj Makkar, Deepak L. Bhatt, and James P. Howard. European Heart Journal. Quality of Care & Clinical Outcomes 8 (4): 383–90.

Whom to Treat for Primary Prevention of Atherosclerotic Cardiovascular Disease: The Aspirin Dilemma. Mora, Samia, Chrisandra L. Shufelt, and JoAnn E. Manson. JAMA Internal Medicine 182 (6): 587–89.

Advanced Heart Failure: State of the Art and Future Directions. Masarone, Daniele, Michelle Kittleson, Andrea Petraio, and Giuseppe Pacileo. Reviews in Cardiovascular Medicine 23 (2): 1–14.

Biology or Disparity? Untangling Racial Differences in Val122Ile Transthyretin Cardiac Amyloidosis. Kittleson, Michelle M. Journal of Cardiac Failure 28 (6): 960–62.

Renal Artery Variations in Patients With Mild-to-Moderate Hypertension From the RADIANCE-HTN SOLO Trial. Sanghvi, Kintur, Yale Wang, Joost Daemen, Anthony Mathur, Ajay Jain, Suhail Dohad, Marc Sapoval, et al. Cardiovascular Revascularization Medicine 39 (June): 58–65.

The Impact of Anxiety Level on Decision to Seek Medical Care of Non-COVID Cardiac Patients During the Pandemic Outbreak--Single-Center Experience in Israel. Koren, Ofir, Saleem Abu Rajab, Mohammad Barbour, Moriah Shachar, Amit Shahar, Khaled Zubidat, Wasim Slim, et al. Reviews in Cardiovascular Medicine 23 (2): 1–11.

Imaging 

The Imperative to Assess Physical Function among All Patients Undergoing Stress Myocardial Perfusion Imaging. Rozanski, Alan, Daniel S. Berman, and Ami E. Iskandrian. Journal of Nuclear Cardiology29 (3): 946–51.

Quantifying Microcalcification Activity in the Thoracic Aorta. Fletcher, Alexander J., Maria Lembo, Jacek Kwiecinski, Maaz B. J. Syed, Jennifer Nash, Evangelos Tzolos, Rong Bing, et al. Journal of Nuclear Cardiology 29 (3): 1372–85.

Prognostic Value of Early Left Ventricular Ejection Fraction Reserve During Regadenoson Stress Solid-State SPECT-MPI. Otaki, Yuka, Mathews B. Fish, Robert J. H. Miller, Mark Lemley, and Piotr J. Slomka. Journal of Nuclear Cardiology 29 (3): 1219–30.

Assessment of Left and Right Ventricular Functional Parameters Using Dynamic Dual-Tracer [13N]NH3 and [18F]FDG PET/MRI. Rasul, Sazan, Dietrich Beitzke, Tim Wollenweber, Ivo Rausch, Martin Lyngby Lassen, Marie Elisabeth Stelzmüller, Markus Mitterhauser, et al. Journal of Nuclear Cardiology 29 (3): 1003–17.

Evidence for the Normalization Effects of Medication for Opioid Use Disorder on Functional Connectivity in Neonates With Prenatal Opioid Exposure. Liu, Janelle, Karen Grewen, and Wei Gao. The Journal of Neuroscience 42 (22): 4555–66.

OSCILLATE: A Low-Rank Approach for Accelerated Magnetic Resonance Elastography. McIlvain, Grace, Alexander M. Cerjanic, Anthony G. Christodoulou, Matthew D. J. McGarry, and Curtis L. Johnson. Magnetic Resonance in Medicine, June.

Vascular Biomechanics and Molecular Disease Activity in the Thoracic Aorta: A Novel Imaging Method.  Minderhoud, Savine C. S., Alexander J. Fletcher, Gillian MacNaught, Sebastien Cadet, Suze-Anne Korteland, Isabella Kardys, Dimitris Rizopoulos, et al. European Heart Journal. Cardiovascular Imaging, June, jeac090.

18F-NaF PET/MRI for Detection of Carotid Atheroma in Acute Neurovascular Syndrome. Kaczynski, Jakub, Stephanie Sellers, Michael A. Seidman, Maaz Syed, Martin Dennis, Gillian Mcnaught, Maurits Jansen, et al. Radiology, June, 212283.

Machine Learning to Predict Abnormal Myocardial Perfusion from Pre-Test Features. Miller, Robert J. H., M. Timothy Hauser, Tali Sharir, Andrew J. Einstein, Mathews B. Fish, Terrence D. Ruddy, Philipp A. Kaufmann, et al. Journal of Nuclear Cardiology, June.

Quantifying Sodium [18F]Fluoride Uptake in Abdominal Aortic Aneurysms. Debono, Samuel, Jennifer Nash, Alexander J. Fletcher, Maaz B. J. Syed, Scott I. Semple, Edwin J. R. van Beek, Alison Fletcher, et al. EJNMMI Research 12 (1): 33.

Medicine 

Filgotinib or lanraplenib in moderate to severe cutaneous lupus erythematosus: a phase 2, randomized, double-blind, placebo-controlled study. Werth VP, Fleischmann R, Robern M, Touma Z, Tiamiyu I, Gurtovaya O, Pechonkina A, Mozaffarian A, Downie B, Matzkies F, Wallace D. Rheumatology (Oxford). 2022 May 30;61(6):2413-2423. 

Plant Green Pigment of Chlorophyllin Attenuates Inflammatory Bowel Diseases (IBD) by Suppressing Autophagy Activation in Mice. Zhang, Tianci, Ruofei Zhang, Guangfu Zhao, Wei Liu, Liwei Pan, Ying Tong, Mingshan Jiang, et al. American Journal of Physiology. Gastrointestinal and Liver Physiology, May.

Analysis of Relapse by Inflammatory Rasch-Built Overall Disability Scale Status in the PATH Study of Subcutaneous Immunoglobulin in Chronic Inflammatory Demyelinating Polyneuropathy. Merkies, Ingemar S. J., Ivo N. van Schaik, Vera Bril, Hans-Peter Hartung, Richard A. Lewis, Gen Sobue, John-Philip Lawo, Orell Mielke, David R. Cornblath, and PATH study group. Journal of the Peripheral Nervous System: JPNS 27 (2): 159–65.

A Yellow Highlighter. Le, Tammy M. Journal of the American Geriatrics Society 70 (6): 1863–64.

Contributions of the Regional Emerging Special Pathogen Treatment Centers to the US COVID-19 Pandemic Response. Grein, Jonathan D., Jennifer A. Garland, Christa Arguinchona, Maria G. Frank, Brian T. Garibaldi, Amanda Grindle, Angela Hewlett, et al. Health Security 20 (S1): S4–12.

Fecal Immunochemical Test (FIT) versus Colonoscopy: Does Knowing That a Positive FIT Requires a Follow-up Colonoscopy Affect Initial Decision Making in the US? Shergill, Jaspreet, Katherine E. Makaroff, Marie Lauzon, Brennan M. R. Spiegel, and Christopher V. Almario. Preventive Medicine Reports 27 (June): 101825.

Hepatocyte TGF-β Signaling Inhibiting WAT Browning to Promote NAFLD and Obesity Is Associated With Let-7b-5p. Zhao, Jinfang, Lilin Hu, Wenfang Gui, Li Xiao, Weijun Wang, Jing Xia, Huiqian Fan, et al. Hepatology Communications 6 (6): 1301–21.

Osilodrostat for the Treatment of Cushing’s Disease: Efficacy, Stability, and Persistence - Authors’ Reply. Fleseriu, Maria, Frederic Castinetti, Mônica Gadelha, Andrea Giustina, André Lacroix, Shlomo Melmed, John Newell-Price, et al. The Lancet. Diabetes & Endocrinology 10 (6): 385–87.

Quantification of Glomerular Structural Lesions: Associations With Clinical Outcomes and Transcriptomic Profiles in Nephrotic Syndrome. Hodgin, Jeffrey B., Laura H. Mariani, Jarcy Zee, Qian Liu, Abigail R. Smith, Sean Eddy, John Hartman, et al. American Journal of Kidney Diseases 79 (6): 807-819.e1.

Risk Factors for Posttransplantation Mortality in Recipients With Grade 3 Acute-on-Chronic Liver Failure: Analysis of a North American Consortium. Sundaram, Vinay, Sarvanand Patel, Kirti Shetty, Christina C. Lindenmeyer, Robert S. Rahimi, Gianina Flocco, Atef Al-Attar, et al. Liver Transplantation 28 (6): 1078–89.

Site of Death Among Individuals With and Without Dementia in 2016-2018. Gotanda, Hiroshi, Jessica J. Zhang, Haiyong Xu, and Yusuke Tsugawa. Journal of the American Geriatrics Society 70 (6): 1865–67.

The NETting of Pituitary Adenoma: A Gland Illusion. Ho, Ken K. Y., Mônica Gadelha, Ursula B. Kaiser, Martin Reincke, and Shlomo Melmed. Pituitary 25 (3): 349–51.

DOC2b Enhances β-Cell Function via a Novel Tyrosine Phosphorylation-Dependent Mechanism. Chatterjee Bhowmick, Diti, Arianne Aslamy, Supriyo Bhattacharya, Eunjin Oh, Miwon Ahn, and Debbie C. Thurmond. Diabetes 71 (6): 1246–60.

Long-Term Risk of Herpes Zoster Infection in Patients With Ulcerative Colitis Receiving Tofacitinib. Winthrop, Kevin L., Séverine Vermeire, Millie D. Long, Julian Panés, Siew C. Ng, Nicole Kulisek, Rajiv Mundayat, et al. Inflammatory Bowel Diseases, June, izac063.

Pickle Juice Intervention for Cirrhotic Cramps Reduction: The PICCLES Randomized Controlled Trial. Tapper, Elliot B., Najat Salim, Jad Baki, Zhe Zhao, Vinay Sundaram, Vilas Patwardhan, and Samantha J. Nikirk. The American Journal of Gastroenterology 117 (6): 895–901.

The ZIP8/SIRT1 Axis Regulates Alveolar Progenitor Cell Renewal in Aging and Idiopathic Pulmonary Fibrosis. Liang, Jiurong, Guanling Huang, Xue Liu, Forough Taghavifar, Ningshan Liu, Yizhou Wang, Nan Deng, et al. The Journal of Clinical Investigation 132 (11): e157338.

Hyaluronan Synthase 2, a Target of MiR-200c, Promotes Carbon Tetrachloride-Induced Acute and Chronic Liver Inflammation via Regulation of CCL3 and CCL4. Kim, Sun Myoung, Ga Yeon Song, Aeri Shim, Jee Hyung Lee, Cheol Bin Eom, Cheng Liu, Yoon Mee Yang, and Ekihiro Seki. Experimental & Molecular Medicine, June.

For Better or for Worse. Sandesara, Anand. Journal of Pain and Symptom Management 63 (6): e773–74.

Measures of Glucose Homeostasis During and After Duodenal Exclusion Using a Duodenal-Jejunal Bypass Liner in a Normoglycemic, Nonobese Canine Model. Paszkiewicz, Rebecca L., Miguel A. Burch, Isaac Asare Bediako, Hasmik Mkrtchyan, Francesca Piccinini, Marilyn Ader, Catherine Bresee, and Richard N. Bergman. Surgery for Obesity and Related Diseases 18 (6): 694–702.

Multiple Modes of Action Mediate the Therapeutic Effect of Intravenous IgG in Experimental Epidermolysis Bullosa Acquisita. Pipi, Elena, Anika Kasprick, Hiroaki Iwata, Stephanie Goletz, Jennifer E. Hundt, Hengameh Sadeghi, Leon F. Schmidt-Jiménez, et al. The Journal of Investigative Dermatology 142 (6): 1552-1564.e8.

One Patient, No Good Options: The Real Roots of Ambivalence in Medical Decision Making. Kondrat, Andy. The American Journal of Bioethics: AJOB 22 (6): 48–50.

Perception of Interdisciplinary Collaboration between ICU Nurses and Resident Physicians During the COVID-19 Pandemic. Matusov, Yuri, Aliza Matthews, Melissa Rue, Lorraine Sheffield, and Isabel F. Pedraza. Journal of Interprofessional Education & Practice 27 (June): 100501.

Quantitative Image Analysis at Chronic Lung Allograft Dysfunction Onset Predicts Mortality. Weigt, S. Samuel, Grace-Hyun J. Kim, Heather D. Jones, Allison L. Ramsey, Olawale Amubieya, Fereidoun Abtin, Lila Pourzand, et al. Transplantation 106 (6): 1253–61.

Incidence of Contrast-Associated Acute Kidney Injury in Renal-Competent COVID-19 Patients Undergoing Computed Chest Angiography. Sedaghat, Farzad, Harshna V. Vadvala, Alan Shan, Michael T. McMahon, and Rakhee S. Gawande. Journal of Computer Assisted Tomography, June.

Retention of Functional Mitochondria in Mature Red Blood Cells from Patients With Sickle Cell Disease. Moriconi, Chiara, Monika Dzieciatkowska, Micaela Roy, Angelo D’Alessandro, Philippe Roingeard, June Young Lee, David R. Gibb, et al. British Journal of Hematology, June.

Immunization Using ApoB-100 Peptide-Linked Nanoparticles Reduces Atherosclerosis. Chyu, Kuang-Yuh, Xiaoning Zhao, Jianchang Zhou, Paul C. Dimayuga, Nicole Wm Lio, Bojan Cercek, Noah T. Trac, Eun Ji Chung, and Prediman K. Shah. JCI Insight 7 (11): e149741.

Improvement of Asymmetric Thyroid Eye Disease With Teprotumumab. Ugradar, Shoaib, Yao Wang, Tunde Mester, George J. Kahaly, and Raymond Douglas. The British Journal of Ophthalmology 106 (6): 755–59.

Fgfr2b Signaling Is Essential for the Maintenance of the Alveolar Epithelial Type 2 Lineage During Lung Homeostasis in Mice. Ahmadvand, Negah, Arun Lingampally, Farhad Khosravi, Ivonne Vazquez-Armendariz, Stefano Rivetti, Jochen Wilhelm, Susanne Herold, et al. Cellular and Molecular Life Sciences 79 (6): 302.

When You Think Something Is Wrong – Something IS Wrong: Timely Diagnosis of Anastomotic Leak. Yao, Lucille, and Karen Zaghiyan. Seminars in Colon & Rectal Surgery 33 (2): N.PAG-N.PAG.

Will Apple Devices’ Passive Atrial Fibrillation Detection Prevent Strokes? Estimating the Proportion of High-Risk Actionable Patients with Real-World User Data. Feldman, Keith, Ray G Duncan, An Nguyen, Galen Cook-Wiens, Yaron Elad, Teryl Nuckols, and Joshua M Pevnick. Journal of the American Medical Informatics Association 29 (6): 1040–49.

Neurology 

Brain-on-a-Chip: Recent Advances in Design and Techniques for Microfluidic Models of the Brain in Health and Disease. Amirifar, Leyla, Amir Shamloo, Rohollah Nasiri, Natan Roberto de Barros, Ze Zhong Wang, Bige Deniz Unluturk, Alberto Libanori, et al. Biomaterials 285 (June): 121531.

The Dawn of Disease Modification for Alzheimer’s Disease: Hope and Peril. Tan, Zaldy S. Journal of the American Geriatrics Society 70 (6): 1661–63.

Lesion Size and Shape in Central Vein Sign Assessment for Multiple Sclerosis Diagnosis: An in Vivo and Postmortem MRI Study. Al-Louzi, Omar, Sargis Manukyan, Maxime Donadieu, Martina Absinta, Vijay Letchuman, Brent Calabresi, Parth Desai, et al. Multiple Sclerosis (Houndmills, Basingstoke, England), June, 13524585221097560.

Electrodiagnostic Testing Variability: We Can and Must Do Better. Lewis, Richard A. Clinical Neurophysiology 138 (June): 195–96.

Molecular Profiling of Enteric Nervous System Cell Lineages. Obata, Yuuki, Álvaro Castaño, Todd L. Fallesen, Ana Carina Bon-Frauches, Stefan Boeing, Almaz Huseynova, Sarah McCallum, Reena Lasrado, Tiffany A. Heanue, and Vassilis Pachnis. Nature Protocols, June.

Neurosurgery 

Interhemispheric Connectivity Supports Load-Dependent Working Memory Maintenance for Complex Visual Stimuli. Plaska, Chelsea Reichert, Jefferson Ortega, Bernard A. Gomes, and Timothy M. Ellmore. Brain Connectivity, June.

OBGYN

Role of Robotic Surgery in Benign Gynecology. Truong, Mireille D., and Lauren N. Tholemeier. Obstetrics and Gynecology Clinics of North America 49 (2): 273–86.

Care Levels for Fetal Therapy Centers. Baschat, Ahmet A., Sean B. Blackwell, Debnath Chatterjee, James J. Cummings, Stephen P. Emery, Shinjiro Hirose, Lisa M. Hollier, et al. Obstetrics and Gynecology 139 (6): 1027–42.

Pregnancy Anxiety, Placental Corticotropin-Releasing Hormone and Length of Gestation. Ramos, Isabel F., Kharah M. Ross, Gabrielle R. Rinne, Jennifer A. Somers, Roberta A. Mancuso, Calvin J. Hobel, Mary Coussons-Read, and Christine Dunkel Schetter. Biological Psychology, June, 108376.

Reply to Comment on Migraine and Adverse Pregnancy Outcomes: The NuMoM2b Study. Miller, Eliza C., Ronald Wapner, and Natalie Bello. American Journal of Obstetrics and Gynecology, June, S0002-9378(22)00447-1.

Defining Properly Collected Urine: Thresholds to Improve the Accuracy of Urinalysis for Microscopic Hematuria Evaluation in Women. Chen, Andrew, Ashley Caron, Nicholas J. Jackson, Falisha Kanji, Paige Kuhlmann, Christina H. Le, Karyn S. Eilber, Jennifer T. Anger, and A. Lenore Ackerman. Obstetrical & Gynecological Survey 77 (6): 342–43.

Orthopaedics 

Factors Influencing Surgical Management of Proximal Humerus Fractures: Do Shoulder and Trauma Surgeons Differ? Hao, Kevin A., David A. Patch, Logan A. Reed, Clay A. Spitler, John G. Horneff, Jaimo Ahn, Jason A. Strelzow, et al. Journal of Shoulder and Elbow Surgery 31 (6): e259–69.

Is There Clinical Improvement Associated With Intradiscal Therapies? A Comparison Across Randomized Controlled Studies. Ju, Derek G., Linda E. Kanim, and Hyun W. Bae. Global Spine Journal 12 (5): 756–64.

All-Inside Meniscus Repair. Golz, A. G., B. Mandelbaum, and J. L. Pace. Current Reviews in Musculoskeletal Medicine, June.

Impact of Renal Disease on Elective Shoulder Arthroplasty Outcomes for Glenohumeral Osteoarthritis. Hsiue, Peter P., Troy Sekimura, Alfonso Ocampo, Clark J. Chen, Thomas E. Olson, Benjamin V. Kelley, Christos Photopoulos, and Alexandra I. Stavrakis. Seminars in Arthroplasty: JSES 32 (2): 297–304.

Pathology 

NLRP3 Licenses NLRP11 for Inflammasome Activation in Human Macrophages. Gangopadhyay, Anu, Savita Devi, Shivendra Tenguria, Jessica Carriere, Huyen Nguyen, Elisabeth Jäger, Hemisha Khatri, et al. Nature Immunology 23 (6): 892–903.

Well-Differentiated Neuroendocrine Tumour Arising from Diffuse Ganglioneuromatosis: First Reported Case. Cox, Brian K., Bonnie Balzer, Maha Guindi, Alexandra Gangi, and Brent K. Larson. Pathology 54 (4): 488–90.

Efficient Automatic 3D Segmentation of Cell Nuclei for High-Content Screening. Marzec, Mariusz, Adam Piórkowski, and Arkadiusz Gertych. BMC Bioinformatics 23 (1): 203.

Manufacturer Signal-to-Cutoff Threshold Underestimates Cumulative Incidence of SARS-CoV-2 Infection: Evidence from the Los Angeles Firefighters Study. Toubat, Omar, Anders H. Berg, Kimia Sobhani, Karen Mulligan, Acacia M. Hori, Jay Bhattacharya, and Neeraj Sood. The Journal of Applied Laboratory Medicine, June, jfac034.

Pediatrics 

Use of a Donor-Derived Cell-Free DNA Assay to Monitor Treatment Response in Pediatric Renal Transplant Recipients With Allograft Rejection. Steggerda, Justin A., Helen Pizzo, Jonathan Garrison, Xiaohai Zhang, Mark Haas, Irene K. Kim, Stanley C. Jordan, and Dechu P. Puliyanda. Pediatric Transplantation 26 (4): e14258.

Long Term Tolerability and Clinical Outcomes Associated With Tocilizumab in the Treatment of Refractory Antibody Mediated Rejection (AMR) in Pediatric Renal Transplant Recipients. Pearl, Meghan, Patricia L. Weng, Lucia Chen, Aditi Dokras, Helen Pizzo, Jonathan Garrison, Carrie Butler, et al. Clinical Transplantation, June, e14734.

Psychiatry 

Psychosocial Interventions for Patients With Heart Failure and Their Impact on Depression, Anxiety, Quality of Life, Morbidity, and Mortality: A Systematic Review and Meta-Analysis. Chernoff, Robert Alan, Gabrielle Messineo, Sungjin Kim, Demetria Pizano, Samuel Korouri, Itai Danovitch, and Waguih William IsHak. Psychosomatic Medicine 84 (5): 560–80.

Radiation Oncology 

A Comparison of Patient- and Clinician-Reported Acute Toxicity During Radiotherapy for Primary Breast Cancer. Lapen, Kaitlyn, Caroline King, Lior Z. Braunstein, Atif J. Khan, Mitchell R. Kamrava, Erin F. Gillespie, and Kiri A. Cook. International Journal of Radiation Oncology, Biology, Physics, June, S0360-3016(22)00548-X.

The Influence of the Pretreatment Immune State on Response to Radiation Therapy in High Risk Prostate Cancer: A Validation Study from NRG/RTOG 0521. Hall, William A., Theodore G. Karrison, Seth A. Rosenthal, Mahul B. Amin, Leonard G. Gomella, James A. Purdy, A. Oliver Sartor, et al. International Journal of Radiation Oncology, Biology, Physics, June, S0360-3016(22)00555-7.

Surgery

A Proposed Inventory to Assess Changes in Orgasm Function of Transgender Patients Following Gender Affirming Treatments: Pilot Study. Zaliznyak, Michael, Marie Lauzon, Jenna Stelmar, Nance Yuan, Shannon M. Smith, and Maurice M. Garcia. Sexual Medicine 10 (3): 100510.

The Application of Human Factors Engineering to Reduce Operating Room Turnover in Robotic Surgery. Cohen, Tara N., Jennifer T. Anger, Kevin Shamash, Kenneth R. Catchpole, Raymund Avenido, Eric J. Ley, Bruce L. Gewertz, and Daniel Shouhed. World Journal of Surgery 46 (6): 1300–1307.

Surgical Treatment of Granulomatous Breast Deformities Caused by Injection of Foreign Substances in Transgender Women: A Case Series and Algorithm. Cordero, Daniella M., Dhivya Srinivasa, Laura L. Barnes, Edward Ray, and Michael J. Terry. Plastic and Reconstructive Surgery 149 (6): 1312–16.

Practical Approach to Clinical Controversies in Glycemic Control for Hospitalized Surgical Patients. Ware, Lydia R., James F. Gilmore, and Paul M. Szumita. Nutrition in Clinical Practice 37 (3): 521–35.

Low-Intensity Extracorporeal Shockwave Therapy for Diabetic Men With Erectile Dysfunction: A Systematic Scoping Review. Mason, Matthew M., Raghav K. Pai, John M. Masterson, Soum D. Lokeshwar, Kevin Y. Chu, and Ranjith Ramasamy. Andrology, June.