Primary Sjogrens Syndrome
Primary Sjogren's Syndrome (PSS) is a prototype autoimmune condition with marked organ specificity, multiple autoantibodies and lymphocyte dysregulation, as well as tissue/organ damage that is poorly understood. In conjunction with a consortium of PSS researchers centered at the Oklahoma Medical Research Foundation, we are assembling a cohort to study the susceptibility as well as severity and genetic risk for this uncommon yet quite severe clinical syndrome. These patients will be contributing serum and plasma biomarkers, tissue samples and clinical information into a large national consortium. In another effort, in collaboration with David Wong, DDS, of the UCLA School of Dentistry, we have begun to collect saliva specimens to identify biomarker predictors of not only PSS but possibly those PSS patients who evolve into lymphoma.
Program Interactions in Sjogren's syndrome
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