Sleep Smart

Condition: Stroke


Key Inclusion Criteria

  • At least 18 years old
  • Transient ischemic attack with ABCD2≥4 or ischemic stroke within the past 14 days

Key Exclusion Criteria

  • Pre-event inability to perform basic activities of daily living
  • Incarcerated
  • Pregnant

Full Study Name

Sleep for Stroke Management and Recovery Trial (IRB no. 57211)


This study focuses on individuals who have had a recent stroke or transient ischemic attack (TIA, often called a "mini-stroke") and who are still in the hospital (initial hospitalization or rehabilitation stay). The purpose of the study is to determine whether treatment for sleep apnea in patients who have had a stroke or TIA improves recovery from stroke and helps prevent future stroke, heart problems, and death. Sleep apnea is a disorder in which breathing stops or nearly stops repeatedly during sleep. This condition affects most (about 75 out of 100) stroke and TIA patients.

The treatment being tested is called continuous positive airway pressure (CPAP); the U.S. Food and Drug Administration has approved CPAP for the treatment of obstructive sleep apnea. The CPAP is a device that continually adjusts the air pressure needed to keep the airway open. The amount of pressure an individual needs can change depending on body position, sleep stage, nose congestion, medications and other factors.

Principal Investigator

Oana Dumitrascu, MD