Laser Fluorescence for Tissue Identification

Condition: Brain tumors


Key Inclusion Criteria

  • Adult and pediatric patients are eligible
  • Patients with a suspected or pathology-proven brain, breast, head, neck, or skin tumor who are undergoing a tumor resection; or
  • Patients who are undergoing temporal lobectomy as standard of care for epilepsy

Key Exclusion Criteria

  • Patients with medical conditions that prevent them from being a candidate for standard-of-care tumor resection or temporal lobectomy as applicable
  • Patients undergoing burr hole biopsy only of brain tumors; or
  • Patients undergoing needle biopsy only of other solid tumors

Full Study Name

Intraoperative Assessment of Tissue with Time-Resolved Fluorescence Spectroscopy (IRB no. 3444)


The purpose of this study is to evaluate the investigational use of laser-induced fluorescence spectroscopy (LIFS) to detect brain tumors at the time of surgery. LIFS is a technique that utilizes a beam of light (laser) to differentiate tumor tissue from normal brain tissue.

During surgery, a low-intensity light beam will be focused on the surface of the brain. The fluorescence emitted from the brain tissue will then be analyzed by a computer in the operating room to locate tumor tissue.

Financial disclosure

Cedars-Sinai has a financial interest in this study as follows:

  • Cedars-Sinai owns the patent rights related to the device being tested in this study.

Principal Investigator

Chirag Patil, MD