Gonsky R, Fleshner P, Deem RL, Biener-Ramanujan E, Li D, Potdar AA, Bilsborough J, Yang S, McGovern DPB, Targan SR. Association of ribonuclease T2 gene polymorphisms with decreased expression and clinical characteristics of severity in Crohn’s disease. Gastroenterology. 2017 Jul;153(1):219-232. http://www.gastrojournal.org/article/S0016-5085(17)35412-4/fulltext.
Zhang H, Zheng L, McGovern DP, Hamill AM, Ichikawa R, Kanazawa Y, Luu J, Kumagai K, Cilluffo M, Fukata M, Targan SR, et al. Myeloid ATG16L1 facilitates host-bacteria interactions in maintaining intestinal homeostasis. J Immunol. 2017 Mar 1;198(5):2133-2146. http://www.jimmunol.org/content/198/5/2133.
Thomas LS, Targan SR, Tsuda M, Yu QT, Salumbides BC, Haritunians T, Mengesha E, McGovern DP, Michelsen KS. The TNF family member TL1A induces IL-22 secretion in committed human T(h)17 cells via IL-9 induction. J Leukoc Biol. 2017 Mar;101(3):727-737. https://www.ncbi.nlm.nih.gov/pubmed/27733581.
Tschurtschenthaler M, Adolph TE, Ashcroft JW, Niederreiter L, Bharti R, Saveljeva S, Bhattacharyya J, Flak MB, Shih DQ, Fuhler GM, Parkes M, Kohno K, Iwawaki T, Janneke van der Woude C, Harding HP, Smith AM, Peppelenbosch MP, Targan SR, et al. Defective ATG16L1-mediated removal of IRE1α drives Crohn’s disease-like ileitis. J Exp Med. 2017 Feb;214(2):401-422. http://jem.rupress.org/content/214/2/401.
Feagan BG, Sandborn WJ, Gasink C, Jacobstein D, Lang Y, Friedman JR, Blank MA, Johanns J, Gao LL, Miao Y, Adedokun OJ, Sands BE, Hanauer SB, Vermeire S, Targan S, et al. Ustekinumab as induction and maintenance therapy for Crohn’s disease. N Engl J Med. 2016 Nov 17;375(20):1946-1960. http://www.nejm.org/doi/full/10.1056/NEJMoa1602773.
Chu H, Khosravi A, Kusumawardhani IP, Kwon AH, Vasconcelos AC, Cunha LD, Mayer AE, Shen Y, Wu WL, Kambal A, Targan SR, et al. Gene-microbiota interactions contribute to the pathogenesis of inflammatory bowel disease. Science. 2016 May 27;352(6289):1116-1120. http://science.sciencemag.org/content/352/6289/1116.
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This Web page converts English to other languages â â using an automated tool called Microsoft Translatorâ ¢. Translations may include errors or change the intended meaning of the text. Please consult your doctor about any medical information.
Translations may not be available for some articles, including PDF documents, maps, video legends and text that appears in the photos. Also, some of the features on the website may not work in the translated versions.