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Stripp Lab
The goals of the Stripp Laboratory are to understand mechanisms of normal tissue maintenance and defects associated with acute and chronic lung disease. The Stripp Lab integrates basic mechanistic studies in the research laboratory with studies that use patient-derived clinical samples to define novel therapeutic targets with potential to promote lung regeneration and ameliorate or reverse lung disease. Areas of disease focus include acute lung injury resulting from viral infection and chronic lung diseases including idiopathic pulmonary fibrosis, chronic obstructive lung disease and lung cancer.
The Stripp Laboratory is affiliated with the Cedars-Sinai Lung Institute, Board of Governors Regenerative Medicine Institute, Cancer Institute and Department of Medicine.
Overarching interests of the Stripp Laboratory are to define epithelial stem and progenitor cells that maintain the human lung, and to define mechanisms that regulate quiescence versus activation of these reparative cells and renewal versus differentiation in the setting of normal tissue maintenance and lung disease. Studies in the Stripp Lab benefit from the participation of patients receiving clinical care for lung disease who generously provide access to clinical samples that are used to identify candidate cellular and molecular targets for initiation and progression of chronic lung disease.
Collaborations
Internal
- Board of Governors Regenerative Medicine Institute
- Cancer Institute
- Department of Medicine
- Lung Institute
External
- John Belperio, MD, David Geffen School of Medicine at UCLA
- Zea Borok, MD, Keck School of Medicine of University of Southern California
- Scott Randell, PhD, University of North Carolina School of Medicine
- Brigid Hogan, PhD, Duke University School of Medicine
- Darrell Kotton, MD, Center for Regenerative Medicine of Boston University
- Jeffrey Whitsett, MD, Cincinnati Children’s Hospital
- Carla Kim, PhD, Harvard Medical School
Meet Our Team
Learn more about the scientists, faculty members, investigators and other healthcare professionals of the Stripp Laboratory, whose dedicated efforts lead to groundbreaking discoveries.
Yao C, Carraro G, Konda B, Guan X, Mizuno T, Chiba N, Kostelny M, Kurkciyan A, David G, McQualter JL, Stripp BR.
Development. 2017 Jul 15;144(14):2618-2628.
Carraro G, Stripp BR.
Am J Respir Cell Mol Biol. 2017 Jun;56(6):685-686
Xu Y, Mizuno T, Sridharan A, Du Y, Guo M, Tang J, Wikenheiser-Brokamp KA, Perl AT, Funari VA, Gokey JJ, Stripp BR, Whitsett JA.
JCI Insight. 2016 Dec 8;1(20):e90558.
Contact the Stripp Lab
127 S. San Vicente Blvd.
Pavilion, Room A8600
Los Angeles, CA 90048