The Pisarska Laboratory is a reproductive biology laboratory with two major areas of focus:
We are conducting research to determine how the ovary functions and why some women experience premature oocyte and follicle depletion leading to premature ovarian failure. We have focused on a gene known as forkhead L2 (FOXL2) that, when mutated, leads to premature ovarian failure. We are also conducting research on how certain tumors of the ovary, specifically granulosa cell tumors, develop. Different types of FOXL2 mutations lead to granulosa cell tumor formation; we are trying to understand how different FOXL2 mutations alter granulosa cell function leading to tumor formation and follicle depletion.
Learn more about the scientists, faculty members, investigators and other healthcare professionals of the Pisarska Laboratory, whose dedicated efforts lead to groundbreaking discoveries.
Practice Committee of the American Society for Reproductive Medicine.
Fertil Steril. 2016 May 25. pii: S0015-0282(16)61281-5.
Wang ET, Ozimek JA, Greene N, Ramos L, Vyas N, Kilpatrick SJ, Pisarska MD.
Fertil Steril. 2016 Aug;106(2):423-426
Kroener L, Wang ET, Pisarska MD.
Semin Reprod Med. 2016 Jan;34(1):27-35.
Contact the Pisarska Lab
8635 West Third Street
Los Angeles, CA 90048