Research in the Noble Laboratory focuses on cellular and molecular mechanisms of lung inflammation and fibrosis, the role of lung stem cells in pulmonary fibrosis and the role of host defense in lung inflammation and fibrosis. We have clinical expertise in interstitial lung disease and are conducting clinical trials in idiopathic pulmonary fibrosis, bronchiolitis and pulmonary disease related to connective tissue disease. The Noble Laboratory is generously supported by the National Heart, Lung and Blood Institute at the National Institutes of Health.
The Noble Laboratory is affiliated with the Department of Medicine, Pulmonary Division and Women's Guild Lung Institute.
Learn more about the scientists, faculty members, investigators and other healthcare professionals of the Noble Laboratory, whose dedicated efforts lead to groundbreaking discoveries.
Xie T, Liang J, Liu N, Huan C, Zhang Y, Liu W, Kumar M, Xiao R, D'Armiento J, Metzger D, Chambon P, Papaioannou VE, Stripp BR, Jiang D, Noble PW.
J Clin Invest. 2016 Aug 1;126(8):3063-3079.
Li Y, Liang J, Yang T, Monterrosa Mena J, Huan C, Xie T, Kurkciyan A, Liu N, Jiang D, Noble PW.
Matrix Biol. 2016 Mar 15. pii: S0945-053X(16)30029-4.
Lancaster L, Albera C, Bradford WZ, Costabel U, du Bois RM, Fagan EA, Fishman RS, Glaspole I, Glassberg MK, King TE Jr, Lederer DJ, Lin Z, Nathan SD, Pereira CA, Swigris JJ, Valeyre D, Noble PW.
BMJ Open Respir Res. 2016 Jan 12;3(1):e000105.