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Merchant Lab
The Merchant Laboratory is studying how tumor cells interact with their microenvironment and how this interaction contributes to the development and maintenance of cancer. In particular, the Merchant Lab is interested in signaling pathways that confer resistance to chemotherapy or other stem-cell-like properties to cancer cells. Another area of interest is how immune cells are trafficked into the tumor space and how immune cells can be harnessed to treat cancer.
The Merchant Laboratory is affiliated with the Cedars-Sinai Cancer Institute, Regenerative Medicine Institute and Medicine Department.
SoCal Mass Cytometry user group meeting - Cedars-Sinai Nov 1, 2019
Personal Statement
The goal of our lab is to enable high impact clinical research that is guided by leading-edge basic science. The central focus of our research is to understand how changes in the tumor immune microenvironment and stem cell niche regulate the development of cancer, cancer stem cells and normal hematopoietic tissues."
- Multiplex imaging of the tumor microenvironment
- Immune Monitoring
- Hedgehog signaling
- Bioinformatics
Collaborations
External
Meet Our Team
Learn more about the scientists, faculty members, investigators and other healthcare professionals of the Merchant Laboratory, whose dedicated efforts lead to groundbreaking discoveries.
Job Openings
The Merchant Laboratory has several open positions. To look for and apply to an open position with the Merchant Lab, click the link below.
Chaudhry P, Singh M, Triche TJ, Guzman M, Merchant A.
Blood. 2017 Jun;129(26):3465-3475.
Merchant A, Jorapur A, McManus A, Liu R, Krasnoperov V, Chaudhry P, Singh M, Harton L, Agajanian M, Kim M, et al.
Blood Adv. 2017 Aug 28;1(120):1635-1644.
Merchant A, Joseph G, Wang Q, Brennan S, Matsui W.
Blood. 2010 Mar 25;115(12):2391-2396.
Merchant A, Singh A, Matsui W, Biswal S.
Blood. 2011 Dec 15;118(25):6572-6579
Contact the Merchant Lab
127 S. San Vicente Blvd.
Pavilion, A8700
Los Angeles, CA 90048