Publications
See a complete PubMed list of publications by Kate Lawrenson, PhD.
Selected Key Publications
- Haro M, Lawrenson K. Dissecting endometriosis by single-cell transcriptomic and genomic analysis. Nat Genet 55. 168–169 (2023). doi.org/10.1038/s41588-022-01255-0
- Fonseca MAS*, Haro M*, Wright KN*, Lin X*, Abbasi F, Sun J, Hernandez L, Orr NL, Lawrenson K, Choi-Kuaea Y, et al. Single-cell transcriptomic analysis of endometriosis. Nat Genet. 2023 Feb;55(2):255-267. doi:10.1038/s41588-022-01254-1. Epub 2023 Jan 9.
- Nameki R, Shetty A, Dareng E, Tyrer J, Lin X; Ovarian Cancer Association Consortium; Pharoah P, Corona RI, Kar S, Lawrenson K. chromMAGMA: regulatory element-centric interrogation of risk variants. Life Sci Alliance. 2022 Jul 1;5(10):e202201446. doi:10.26508/lsa.202201446. Print 2022 Oct. PMID: 35777959
- Gusev A*, Lawrenson K*, Lin X, Lyra PC, Kar S, Vavra KC, Segato F, Fonseca MAS, Lee JM, Pejovic T, Ovarian Cancer Association Consortium, et al. Multi-tissue transcriptome-wide association study identifies 26 novel candidate susceptibility genes for high grade serous epithelial ovarian cancer [published online ahead of print May 25, 2018].
- Prendergast EN, de Souza Fonseca MA, Dezem FS, Lester J, Karlan BY, Noushmehr H, Lin X, Lawrenson K. Optimizing exosomal RNA isolation for RNA-Seq analyses of archival sera specimens. PLOS One. 2018 May 8;13(5):e0196913.
- Phelan CM, Kuchenbaecker KB, Tyrer JP, Kar SP, Lawrenson K, Winham SJ, Dennis J, Pirie A, Riggan MJ, Chornokur G, et al. Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer. Nat Genet. 2017 May;49(5):680-691.
- Kar SP, Adler E, Tyrer J, Hazelett D, Anton-Culver H, Bandera EV, Beckmann MW, Berchuck A, Bogdanova N, Lawrenson K, et al. Enrichment of putative PAX8 target genes at serous epithelial ovarian cancer susceptibility loci. Br J Cancer. 2017 Feb 14;116(4):524-535.
- Keleman LE, Lawrenson K, Tyrer J, Li Q, Lee JM, Seo JH, Phelan CM, Beesley J, Chen X, Spindler TJ, et al. Genome-wide significant risk associations for mucinous ovarian carcinoma. Nat Genet. 2015;47(8):888-897.
- Lawrenson K, Li Q, Kar S, Seo JH, Tyrer J, Spindler TJ, Lee J, Chen Y, Karst A, Drapkin R, et al. Cis-eQTL analysis and functional validation of candidate susceptibility genes for high-grade serous ovarian cancer. Nat Commun. 2015 Sep 22;6:8234
- Lawrenson K, Lee N, Torres HA, Lee JM, Brueggmann D, Rao PN, Noushmehr H, Gayther SA. Src as a novel therapeutic target for endometriosis. Gynecol Oncol. 2014;135(1):100-107.
Contact the Lawrenson Lab
8700 Beverly Blvd.
Davis Building, Third Floor
Los Angeles, CA 90048