Hong Lab

The Hong Laboratory in the Smidt Heart Institute focuses on understanding the regulation and remodeling of membrane microdomains of cardiomyocytes during heart failure progression. Researchers in the Hong Lab include scientists and medical students with a broad spectrum of backgrounds. Lab members study how cardiomyocyte surface microdomains are organized to concentrate ion channels and signaling proteins for proper function and regulation in normal and failing hearts. The goal of our research is to identify, at the bench, new molecular and cellular targets that can be translated to develop prognostic biomarkers and therapeutic tools for clinical management of heart failure.

The Hong Laboratory is affiliated with the Smidt Heart Institute and Department of Medicine.

  • Function of BIN1-Induced T-Tubule Microdomains
  • Turnover of Membrane Microdomains and Release of Biomarkers
Meet Our Team

Learn more about the scientists, faculty members, investigators and other healthcare professionals of the Hong Laboratory, whose dedicated efforts lead to groundbreaking discoveries.

Xie Y, Hitzeman TC, Zadikany RH, Nikolova AP, Baum R, Xu B, Agvanian S, Melmed GY, McGovern DT, Geft DR, Chang DH, Moriguchi JD, Hage A, Azarbal B, Czer LS, Kittleson MM, Patel JK, Wu AHB, Kobashigawa JA, Hamilton M, Hong TT, Shaw RM.

Online January 7, 2018. https://www.preprints.org/manuscript/201801.0040/v1.

Xu B, Fu Y, Liu Y, Agvanian S, Wirka RC, Baum R, Zhou K, Shaw RM, Hong T.

PLoS Biol. 2017 Aug 14; 15(8):e2002354.

Fu Y, Shaw SA, Naami R, Vuong CL, Basheer WA, Guo X, Hong T.

Circulation. 2016;133(4):388-397.

Contact the Hong Lab

8700 Beverly Blvd.
Davis Building, Room 1026
Los Angeles, CA 90048