Joshua Goldhaber, MD, leads the National Institutes of Health-supported Goldhaber Laboratory that studies the basic science of heart muscle contraction with a special emphasis on understanding how the strength of heart muscle is regulated at the cellular and molecular levels (excitation-contraction coupling). The overarching goal is to find ways to help diseased heart muscle perform beyond expectations.
Collaborations & Resources
Reagents and Resources
- Leica SP5 laser scanning confocal microscope specially outfitted with patch clamp and bridge clamp setups as well as custom-designed perfusion and laser synchronization systems
- Two additional patch clamp setups outfitted with epifluorescence photometry
- Broad array of molecular biology and biochemistry equipment
- Incubators for cell and tissue culture
- High-performance computers for image analysis
- Scimedia Wide Field Optical Mapping System
- IONOPTIX Calcium and Contractility System
Meet Our Team
Learn more about the scientists, faculty members, investigators and other healthcare professionals of the Goldhaber Laboratory, whose dedicated efforts lead to groundbreaking discoveries.
Yue X, Hazan A, Lotteau S, Zhang R, Torrente AG, Philipson KD, Ottolia M, Goldhaber JI.
Cell Calcium. 2020 Jan 30;87:102167. doi: 10.1016/j.ceca.2020.102167. [Epub ahead of print] PubMed PMID: 32028091; NIHMSID:NIHMS1556245.
Cho JH, Kilfoil PJ, Zhang R, Solymani RE, Bresee C, Kang EM, Luther K, Rogers RG, de Couto G, Goldhaber JI, et al.
JCI. Insight. 2018 Oct 4;3(19). pii: 121123.
Torrente AG, Zhang R, Zaini A, Giani JF, Kang J, Lamp ST, Philipson KD, Goldhaber JI.
Proc Natl Acad Sci U S A. 2015 Aug 4;112(31):9769-74. doi: 10.1073/pnas.1505670112. Epub 2015 Jul 20. PubMed PMID: 26195795; PubMed Central PMCID: PMC4534240.