Joshua Goldhaber, MD, leads the National Institutes of Health-supported Goldhaber Laboratory that studies the basic science of heart muscle contraction with a special emphasis on understanding how the strength of heart muscle is regulated at the cellular and molecular levels (excitation-contraction coupling). The overarching goal is to find ways to help diseased heart muscle perform beyond expectations.
Collaborations & Resources
Reagents and Resources
- Leica SP5 laser scanning confocal microscope specially outfitted with patch clamp and bridge clamp setups as well as custom-designed perfusion and laser synchronization systems
- Two additional patch clamp setups outfitted with epifluorescence photometry
- One giant patch setup for oocytes
- Broad array of molecular biology and biochemistry equipment
- Incubators for cell and tissue culture
- High-performance computers for image analysis
Meet Our Team
Learn more about the scientists, faculty members, investigators and other healthcare professionals of the Goldhaber Laboratory, whose dedicated efforts lead to groundbreaking discoveries.
Cho JH, Kilfoil PJ, Zhang R, Solymani RE, Bresee C, Kang EM, Luther K, Rogers RG, de Couto G, Goldhaber JI, et al.
JCI. Insight. 2018 Oct 4;3(19). pii: 121123.
Bögeholz N, Pauls P, Dechering DG, Frommeyer G, Goldhaber JI, Pott C, Eckardt L, Müller FU, Schulte JS.
Front Pharmacol. 2018 Aug 21;9:933.
Cho JH, Zhang R, Aynaszyan S, Holm K, Goldhaber JI, Marbán E, Cingolani E.
Circ Arrhythm Electrophysiol. 2018 Aug;11(8):e006452.