Instrumentation

Siemens MAGNETOM Vida 3T MRI

  • Human and large animal imaging
  • First MRI scanner with BioMatrix Technology, allowing for consistent, high-quality personalized exams with less scan failure.
  • GPU-accelerated inline compressed sensing for cardiac cine imaging
  • Free-breathing dynamic liver exams powered by compressed sensing GRASP-VIBE
  • Reliable and distortion-free whole-body DWI scans enabled by novel SliceAdjust and CoilShim technologies
  • Simultaneous Multi-Slice (SMS) significantly reduces acquisition time for brain and abdominal diffusion imaging
  • MR elastography and LiverLab package for quantitative liver assessment
  • Brain functional MRI with task presentation systems
  • Diffusion imaging: ADC mapping, fiber tracking
  • Angiography: non-contrast or contrast-enhanced
  • Vascular imaging: angiography, vessel wall imaging
  • Cardiac imaging: perfusion, diffusion, function, late-enhancement, T1/T2 mapping
  • Body imaging: spine, cancer characterization, respiratory motion characterization
  • Molecular imaging: cell tracking, targeted enhancement

Siemens Biograph mMR MR-PET

  • Human and large animal imaging
  • True simultaneous MR and PET whole body acquisition resulting in improved co-registration of PET and MRI images, shorter overall imaging times and ability to observe rapidly changing physiological processes simultaneously
  • Available for research and clinical (standard-of-care) use
  • 3T MRI similar to Verio system (see above)
  • Functional MRI task presentation system
  • Multinuclear MR spectroscopy available

Bruker BioSpin 9.4T micro-MRI

  • Small animal imaging
  • 1H, 15N, 13C and X nuclei imaging and spectroscopy for in vivo and molecular MRI applications
  • Proton spectroscopy, single voxel, 2D and 3D capabilities
  • Metabolic composition and fat analysis
  • Diffusion imaging with fiber tracking capability
  • Angiography
  • Relaxation time measurements and analysis (T1 and T2)
  • Stroke detection, e.g., cerebral blood flow, diffusion tensor imaging
  • Cardiac imaging and function measurement
  • Tumor imaging
  • Longitudinal size analysis

Scanco vivaCT40 micro-CT

  • Small animal in vivo and specimens
  • Outstanding high resolution CT (10 µm)
  • Respiratory gating
  • 3D morphology of cartilage and bone
  • Analysis of visceral and subcutaneous adiposity
  • Imaging of tissue engineering scaffold
  • Hierarchical micro imaging for multi-scale analysis of large vascular networks
  • 3D evaluation of the trabecular and cortical structure
  • Bone volume measurement
  • Quantitative imaging of lung tumors

IVIS® Spectrum Optical Imaging System

  • Whole-body in vivo for small animals
  • High resolution fluorescence and bioluminescence
  • Multiple labels
  • Relative quantitative analysis
  • Full spectral tunability
  • Epi-illumination
  • Trans-illumination
  • Longitudinal analysis and quantification
  • Absolute calibration
  • Multimodal co-registration (PET, CT, MRI)
  • Spectral unmixing
  • Optimal applications: Oncology imaging, stem cell tracking and analysis, drug delivery, cardiovascular diseases, angiogenesis, infection disease, inflammation, pulmonary

IVIS® Lumina XR Optical Imaging System

  • Whole-body in vivo for small animals
  • High resolution fluorescence and bioluminescence with precise x-ray overlay option
  • Multiple labels
  • Relative quantitative analysis
  • Full spectral tunability
  • Epi-illumination
  • Trans-illumination
  • Longitudinal analysis and quantification
  • Absolute calibration
  • Multimodal co-registration (PET, CT, MRI)
  • Spectral unmixing
  • Optimal applications: Oncology imaging, stem cell tracking and analysis, drug delivery, cardiovascular diseases, angiogenesis, infection disease, inflammation, pulmonary

CRi Maestro Fluorescence

  • High resolution fluorescence
  • Multiple labels
  • Relative quantitative analysis
  • Applications: Fluorescent tumor models, antibody based assays, molecular targeting agents, fluorescent drug pharmacokinetics, angiogenesis markers

Precision X-Ray X-RAD SmART

  • A small animal image guided irradiation system with a fully integrated bioluminescence imaging platflorm
  • Image guided targeting precision up to 0.1mm
  • Fully automated registration with CT
  • Precise tumor localization for non-palpable tumors
  • Combines Monte Carlo calculation algorithms to rapidly devise treatment plans
  • Gold standard accuracy for static beams, arcs, and non-coplanar treatments across single and multiple isocenters
  • Measure tumor viability

Notting Hill Devices Preclinical Scanner (4Dx)

  • A small animal preclinical scanner
  • Four-dimensional CT scanner designed for measuring respiratory function and health
  • High levels of sensitivity
  • Offers extremely high-resolution and high-sensitivity scanning
  • Can be used as an X-ray device, 3D CT scanner and a 4D CT scanner
  • Raw data is analyzed with pioneering 4Dx lung imaging software
Contact the Imaging Core

8700 Beverly Blvd. 
Davis Building, G-140
Los Angeles, CA 90048

Fax: 310-967-0639