Biobanking

The Biobank and Translational Research Core collects, stores, manages and distributes biospecimens collected under Institutional Review Board (IRB)-approved protocols.

The Core currently houses more than 60,000 specimens. Specimen types in routine collections include:

  • Tissue
    • Frozen     
    • Fresh for cell isolation
    • Cryopreserved for cell culture and xenografts
    • Formalin-fixed and paraffin-embedded (FFPE)
    • Tissue microarray
  • Blood
    • Plasma
    • Serum
    • Buffy coat
    • Peripheral blood mononuclear cells (PBMCs)
  • Body Fluids
    • Cerebrospinal fluid
    • Urine
    • Others

Custom Biospecimen Collection or Processing Requests


The Biobank and Translational Core can implement your IRB-approved biospecimen collection and/or processing protocol based on your specifications

Request Examples
  • Custom biospecimen collection
    • Tissue collected from the tumor site, proximal and distal to the tumor
  • Custom biospecimen processing
    • Peripheral blood mononuclear cell isolation
    • Bone marrow mononuclear cell isolation
    • Sputum cell deposition, immobilization and fixation

Prospective Collection of Remnant Tissue and Blood/Body Fluids


Clinical Annotation with Biospecimens


Researchers can request:

  • Data related to tissue collection, storage and distribution
  • Pathology report information
  • Clinical follow-up, disease progression 
  • Clinical follow-up, treatment data

Tissue from Pathology Archive


Research pathologists can search for cases in the pathology department archive to provide FFPE tissue block slide recuts and/or tissue cores, as well as pathology report data.

General Information

Storage


The Biobank and Translational Core houses 30 large LN₂ tanks (with 26 racks each, 13 boxes per rack, 81 samples per box) that are filled automatically, and 25 −80°C freezers (24 racks each, 20 boxes per rack, 81 samples per box). All units are monitored with wireless probes that generate automated notifications when status changes occur.

Rapid Autopsy Program


The Rapid Autopsy Program is a new service of the Biobank and Translational Research Core that is initially being implemented for the brain and spinal cord from amyotrophic lateral sclerosis patients. This service will be expanded soon to include brains from Alzheimer's disease patients, as well as for various organs and tissues from control patients with no major pathology or disease. In the future, we plan to expand this service to cancer patients.

Quick Links

We use the iLab Solutions Online Core Management System to process all service requests.

Have Questions or Need Help?

Contact us if you have questions or would like to learn more about the Biobank and Translational Research Core at Cedars-Sinai.

Spielberg, Room 110
8723 W. Alden Drive
Los Angeles, CA 90048

Histology Lab
Biospecimens