
Clive N. Svendsen, PhD
- The doctor practices in an office or specialty that we currently do not survey.
- The doctor has not yet received the minimum number of patient satisfaction surveys (30) to be eligible for display.

- The doctor practices in an office or specialty that we currently do not survey.
- The doctor has not yet received the minimum number of patient satisfaction surveys (30) to be eligible for display.
Clive N. Svendsen, PhD
- The doctor practices in an office or specialty that we currently do not survey.
- The doctor has not yet received the minimum number of patient satisfaction surveys (30) to be eligible for display.

Clive N. Svendsen, PhD
Languages
- English,
Gender
Male
Experience
31 Years
Experience
Specialties
Area in which a healthcare provider is highly trained and often board certified.
1
- Research
Programs
Cedars-Sinai clinical programs this provider is part of:
1
Research Areas
Dr. Clive Svendsen did his predoctoral training at Harvard University. He received his PhD from the University of Cambridge in England, where he subsequently became a Welcome Fellow and established a laboratory focusing on stem cell research. He then moved to the University of Wisconsin in 2000 as Professor of Neurology and Anatomy and founded their Stem Cell and Regenerative Medicine Center. In 2010, he moved to Los Angeles and founded the Cedars-Sinai Board of Governors Regenerative Medicine Institute (RMI), which currently has 23 faculty members and over 120 staff. A main focus of the Institute is to both model and treat various human diseases with the use of induced pluripotent stem cells (or iPSCs), which are adult human cells taken back in time to a young stem cell state capable of making any tissue of the human body. At the heart of the RMI is the Cedars-Sinai Biomanufacturing Center which manufactures iPSCs and other cell types for research purposes and clinical trials. Additionally, Dr. Svendsen maintains a large lab that focuses on modeling neurodegenerative diseases including Spinal Muscular Atrophy and Amyotrophic Lateral Sclerosis (ALS), as well as Huntington’s, Parkinson’s and Alzheimer’s Disease. Using “organ on chip” technology that combines stem cells and engineering, Dr. Svendsen is creating multicellular human systems for research and drug development. He has received many recognitions for this work, including a recent feature on the front cover of National Geographic as “The Future of Medicine”. The other focus of his lab involves cutting-edge clinical trials using combinations of stem cells and growth factors. He spearheaded one of the first clinical trials to deliver a growth factor (GDNF) to patients with Parkinson’s Disease, and is currently working closely with neurosurgeons, neurologists and other scientists to develop novel ways of using stem cells modified to release GDNF for Parkinson’s patients. He is also finding ways to use stem cells for other neurological diseases such as Huntington’s and Alzheimer’s Disease, and is leading a new clinical trial using stem cells to treat an incurable eye disease Retinitis Pigmentosa. Finally, Dr. Svendsen has a long-standing interest in ALS and he was the Sponsor of the first-ever clinical trial delivering stem cells and GDNF to patients that was recently completed at Cedars-Sinai.
Titles
- Professor, Biomedical Sciences
- Director, Board of Governors Regenerative Medicine Institute
- Kerry and Simone Vickar Family Foundation Distinguished Chair in Regenerative Medicine
- Executive Director, Board of Governors Regenerative Medicine Institute
- Professor, Medicine
Education & Training
-
Jesus College, Cambridge
Degrees - Completed 1991
-
King's College London
Degrees - Completed 1983
Achievements
-
6
Awards and Honors
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4
Publications
Awards and Honors
- Board, Emulate Incorporated, Organ on a Chip Company
- Huntington Disease Trailblazer Award, Huntington’s Disease Society of America
- Kerry and Simone Vickar Family Foundation Distinguished Chair in Regenerative Medicine
- Shelia Essey Award, American Academy of Neurology
- Bernard Sanberg Memorial Award for Brain Repair
- Statuette Award, International Academy for Child Brain Development
Publications
A full list of this provider’s research publications can be found on their research profile or PubMed.
- Thomsen GM, Gowing, Latter J, Chen M, Vit JP, Staggenborg K, Avalos P, Alkaslasi M, Ferraiuolo L, Likhite S, Kaspar BK, Svendsen CN. Delayed disease onset and extended survival in the SOD1G93A rat model of amyotrophic lateral sclerosis after suppression of mutant SOD1 in the motor cortex. J Neurosci. 2014;34:15587-600.
- Lu XH, Mattis VB, Wang N, Al-Ramahi I, van den Berg N, Fratantoni SA, Waldvogel H, Greiner E, Osmand A, Elzein K, Xiao J, Dijkstra S, de Pril R, Vinters HV, Faull R, Signer E, Kwak S, Marugan JJ, Botas J, Fischer DF, Svendsen CN, et al. Targeting ATM ameliorates mutant Huntington toxicity in cell and animal models of Huntington’s disease. Sci Transl Med. 2014;6(268):268ra178.
- Lu B, Lin Y, Tsai Y, Girmans S, Adamus G, Jones MK, Shelley B, Svendsen C, Wang S. A Subsequent Human Neural Progenitor Transplant in to the Degenerate Retina Does Not Compromise Initial Graft Survival or Therapeutic Efficacy. PLoS One. 2015;4(1):7.
- Kong SY, Park MH, Lee M, Kim JO, Lee HR, Han BW, Svendsen CN, Sung SH, Kim HJ. Kuwanon v inhibits proliferation, promotes cell survival and increases neurogenesis of neural stem cells. PLoS One. 2015;10(2):e0118188.