
Caroline Jefferies, PhD
No patient rating & comments.
Why?
- The doctor practices in an office or specialty that we currently do not survey.
- The doctor has not yet received the minimum number of patient satisfaction surveys (30) to be eligible for display.

No patient rating & comments.
Why?
- The doctor practices in an office or specialty that we currently do not survey.
- The doctor has not yet received the minimum number of patient satisfaction surveys (30) to be eligible for display.
Caroline Jefferies, PhD
No patient rating & comments.
Why?
- The doctor practices in an office or specialty that we currently do not survey.
- The doctor has not yet received the minimum number of patient satisfaction surveys (30) to be eligible for display.

Caroline Jefferies, PhD
Languages
- English,
Gender
Female
Experience
25 Years
Experience
Research Areas
Education & Training
-
Trinity College
Degrees - Completed 1997
-
Trinity College
Degrees - Completed 1993
Achievements
-
7
Awards and Honors
-
5
Publications
Awards and Honors
- Senior Editor: American Journal of Clinical and Experimental Immunology
- Science Foundation Ireland Principal Investigator Award
- International Cytokine Society Outstanding Scholar Award
- Enterprise Ireland Fellowship
- Science Foundation Ireland Principal Investigator Career Advancement Award
- Editor: Clinical Immunology
- International Cytokine Society Sheldon Wolff Prize In Cytokine Research Award
Publications
- Higgs R, Ní Gabhann J, Ben Larbi N, Breen EP, Fitzgerald KA, Jefferies CA. The E3 ubiquitin ligase Ro52 negatively regulates IFN-beta production post-pathogen recognition by polyubiquitin-mediated degradation of IRF3. J Immunol. 2008;181(3):1780-1876.
- Smith S, Gabhann JN, Higgs R, Stacey K, Wahren-Herlenius M, Espinosa A, Totaro MG, Sica A, Ball E, Bell A, Johnston J, Browne P, O'Neill L, Kearns G, Jefferies CA. Enhanced interferon regulatoryfactor 3 binding to the IL-23p19 promoter correlates with enhanced IL-23 expression in systemic lupus erythematosus. Arthritis Rheum. 2012;64(5):1601-1609.
- Byrne JC, Ní Gabhann J, Stacey KB, Coffey BM, McCarthy E, Jefferies CA. Btk is required for apoptotic cell uptake via regulating the phosphorylation and localisation of Calreticulin. J Immunol. 2013;190(10):5207-5215.
- Jefferies C, Wynne C, Higgs R. Antiviral TRIMs: friend or foe in autoimmune and autoinflammatory disease? Nat Rev Immunol. 2011;11(9):617-625.
- Smith S, Ní Gabhann J, McCarthy E, Coffey B, Mahony R, Byrne JC, Stacey K, Ball E, Bell A, Cunnane G, Doran MF, Molloy ES, Lee RZ, Harvey B, Kearns G, Jefferies CA. Estrogen receptor α regulates tripartite motif-containing protein 21 expression, contributing to dysregulated cytokine production in systemic lupus erythematosus. Arthritis Rheumatol. 2014;66 (1):163-172.