Lupus Clinical Repository

Condition: Systemic lupus erythematosus


Key Inclusion Criteria

  • Lupus-affected:
    • 12 years old or older at time of consent
    • Diagnosis that satisfies the 1982 American College of Rheumatology's criteria for the classification systemic lupus erythematosus as revised in 1997
  • Family members of lupus-affected:
    • A non-affected or affected first-degree relative or an affected second-degree relative 
    • At least 12 years old at time of consent 
  • Healthy participants:
    • Healthy volunteers, including non-affected relatives who are not first-degree relatives of participants
    • Adults who are at least 18 years old

Key Exclusion Criteria

  • Inability to provide consent
  • Inability to cooperate with the study

Full Study Name

Lupus Clinical Repository (IRB no. 19627)


The purpose of this study is to increase knowledge about lupus and its causes, and to improve treatment and care. The study will collect blood samples, which will be used in future studies to understand biomarkers and genetic and immune pathways that are important in lupus. The blood samples will also help enable the development of new drugs or tests for lupus patients. Clinical data, DNA and RNA will also be collected.

The Clinical Repository makes possible ongoing research in lupus and other rheumatological disorders, such as rheumatoid arthritis and ankylosing spondylitis, at Cedars-Sinai.

Principal Investigator

Caroline Jefferies, PhD

Bryan Gonzalez