The PROVIDE Study

Condition: Preeclampsia and Perinatal Mood and Anxiety Disorders

Eligibility

Key Inclusion Criteria

  • At least 18 years old
  • Women who experience gestational hypertension or preeclampsia with or without severe features

Key Exclusion Criteria

  • Current substance abuse or psychosis

Full Study Name

Preeclampsia Research on Vitamin D, Inflammation and Depression (IRB no. 44664)

Summary

This study focuses on patients who are pregnant and in their third trimester of pregnancy. The purpose of the study is to evaluate the anti-inflammatory role of vitamin D in reproductive-aged women and its association with gestational hypertension, preeclampsia and depression. Researchers aim to provide new information implicated in the development of preeclampsia (a condition that may include hypertension, tissue swelling and kidney stress) and postpartum depression.

Additionally, the study is designed to understand how early mental health screening and evaluation can help pregnant women reduce their risk of developing postpartum depression. Evaluating the effectiveness of this mental health screening, education and referral program at Cedars-Sinai will provide valuable patient-centered data that may be used in future services planning. Data will be collected from medical records, and participants will be asked to complete questionnaires, among other research procedures.


Principal Investigator

Eynav Accortt, PhD

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