Neuronal Correlates of Behavior During DBS

Condition: Movement disorders


Key Inclusion Criteria

  • Patients with movement disorder undergoing surgical implantation of DBS electrodes for treatment of a movement disorder
  • At least 18 years old
  • Ability to comprehend and perform simple behavioral tasks by pressing buttons on a laptop computer in response to questions

Key Exclusion Criteria

  • Children
  • Pregnant women

Full Study Name

Neuronal Correlates of Behavior in Deep Brain Nuclei During Deep Brain Stimulation (DBS) (IRB no. 30163)


This study focuses on individuals who have a movement disorder and are undergoing surgical insertion of electrodes into the brain to treat their movement disorder. The purpose of the study is to measure the activity of individual nerve cells (neurons) and collections of nerve cells (local field potentials) in the brain during simple learning, memory, decision-making or problem-solving tasks, as well as before and during voluntary movement.

Measuring the activity of these brain areas in response to such tasks may improve understanding of the mechanisms by which the brain processes, stores, consolidates and recalls a variety of memories and problem-solving strategies. Participation in the study is expected to last for the time period that the patient is undergoing surgical implantation of deep brain stimulation (DBS) electrodes.

Principal Investigator

Adam Mamelak, MD